Inoculação de genótipos de feijão carioca com bactérias diazotróficas.

O objetivo deste trabalho foi avaliar o comportamento de linhagens e cultivares de feijoeiro comum, tipo carioca, inoculadas com estirpes de Rizhobium tropici.CONAFE

Blau syndrome : cross-sectional data from a multicentre study of clinical, radiological and functional outcomes

OBJECTIVE: To report baseline articular, functional and ocular findings of the first international prospective cohort study of Blau syndrome (BS). METHODS: Three-year, multicentre, observational study on articular, functional (HAQ, Childhood HAQ and VAS global and pain), ophthalmological, therapeutic and radiological data in BS patients. RESULTS: Baseline data on the first 31 recruited patients (12 females and 19 males) from 18 centres in 11 countries are presented. Of the 31 patients, 11 carried the p.R334W NOD2 mutation, 9 the p.R334Q and 11 various other NOD2 missense mutations; 20 patients were sporadic and 11 from five BS pedigrees. Median disease duration was 12.8 years (1.1-57). Arthritis, documented in all but one patient, was oligoarticular in 7, polyarticular in 23. The median active joint count was 21. Functional capacity was normal in 41%, mildly impaired in 31% and moderate-severe in 28% of patients. The most frequently involved joints at presentation were wrists, ankles, knees and PIPs. On radiographs, a symmetrical non-erosive arthropathy was shown. Previously unknown dysplastic bony changes were found in two-thirds of patients. Ocular disease was documented in 25 of 31 patients, with vitreous inflammation in 64% and moderate-severe visual loss in 33%. Expanded manifestations (visceral, vascular) beyond the classic clinical triad were seen in 52%. CONCLUSION: BS is associated with severe ocular and articular morbidity. Visceral involvement is common and may be life-threatening. Bone dysplastic changes may show diagnostic value and suggest a previously unknown role of NOD2 in bone morphogenesis. BS is resistant to current drugs, suggesting the need for novel targeted therapies

Blau Syndrome-Associated Uveitis: Preliminary Results From an International Prospective Interventional Case Series

PURPOSE: Provide baseline and preliminary follow-up results in a 5-year longitudinal study of Blau syndrome. DESIGN: Multicenter, prospective interventional case series. METHODS: Baseline data from 50 patients from 25 centers worldwide, and follow-up data for patients followed 1, 2, or 3 years at the end of study enrollment. Ophthalmic data were collected at baseline and yearly visits by means of a standardized collection form. RESULTS: Median age at onset of eye disease was 60 months and duration of eye disease at baseline 145 months. At baseline 38 patients (78%) had uveitis, which was bilateral in 37 (97%). Eight patients (21%) had moderate to severe visual impairment. Panuveitis was found in 38 eyes (51%), with characteristic multifocal choroidal infiltrates in 29 eyes (39%). Optic disc pallor in 9 eyes (12%) and peripapillary nodules in 9 eyes (12%) were the commonest signs of optic nerve involvement. Active anterior chamber inflammation was noted in 30 eyes (40%) at baseline and in 16 (34%), 17 (57%), and 11 (61%) eyes at 1, 2, and 3 years, respectively. Panuveitis was associated with longer disease duration. At baseline, 56 eyes (75%) were on topical corticosteroids. Twenty-six patients (68%) received a combination of systemic corticosteroids and immunomodulatory therapy. CONCLUSIONS: Blau uveitis is characterized by progressive panuveitis with multifocal choroiditis, resulting in severe ocular morbidity despite continuous systemic and local immunomodulatory therapy. The frequency and severity of Blau uveitis highlight the need for close ophthalmologic surveillance as well as a search for more effective therapies

Health related quality of life measure in systemic pediatric rheumatic diseases and its translation to different languages: an international collaboration

Background: Rheumatic diseases in children are associated with significant morbidity and poor health-related quality of life (HRQOL). There is no health-related quality of life (HRQOL) scale available specifically for children with less common rheumatic diseases. These diseases share several features with systemic lupus erythematosus (SLE) such as their chronic episodic nature, multi-systemic involvement, and the need for immunosuppressive medications. HRQOL scale developed for pediatric SLE will likely be applicable to children with systemic inflammatory diseases.Findings: We adapted Simple Measure of Impact of Lupus Erythematosus in Youngsters (SMILEY (c)) to Simple Measure of Impact of Illness in Youngsters (SMILY (c)-Illness) and had it reviewed by pediatric rheumatologists for its appropriateness and cultural suitability. We tested SMILY (c)-Illness in patients with inflammatory rheumatic diseases and then translated it into 28 languages. Nineteen children (79% female, n= 15) and 17 parents participated. the mean age was 12 +/- 4 years, with median disease duration of 21 months (1-172 months). We translated SMILY (c)-Illness into the following 28 languages: Danish, Dutch, French (France), English (UK), German (Germany), German (Austria), German (Switzerland), Hebrew, Italian, Portuguese (Brazil), Slovene, Spanish (USA and Puerto Rico), Spanish (Spain), Spanish (Argentina), Spanish (Mexico), Spanish (Venezuela), Turkish, Afrikaans, Arabic (Saudi Arabia), Arabic (Egypt), Czech, Greek, Hindi, Hungarian, Japanese, Romanian, Serbian and Xhosa.Conclusion: SMILY (c)-Illness is a brief, easy to administer and score HRQOL scale for children with systemic rheumatic diseases. It is suitable for use across different age groups and literacy levels. SMILY (c)-Illness with its available translations may be used as useful adjuncts to clinical practice and research.Rutgers State Univ, Robert Wood Johnson Med Sch, New Brunswick, NJ 08903 USARutgers State Univ, Child Hlth Inst New Jersey, New Brunswick, NJ 08901 USAHosp Special Surg, New York, NY 10021 USAUniv Michigan, Ann Arbor, MI 48109 USARed Cross War Mem Childrens Hosp, Cape Town, South AfricaAin Shams Univ, Pediat Allergy Immunol & Rheumatol Unit, Cairo, EgyptAin Shams Univ, Pediat Rheumatol Pediat Allergy Immunol & Rheum, Cairo, EgyptKing Faisal Specialist Hosp & Res Ctr, Riyadh 11211, Saudi ArabiaCharles Univ Prague, Prague, Czech RepublicGen Univ Hosp, Prague, Czech RepublicUniv Hosp Motol, Dept Pediat, Prague, Czech RepublicAarhus Univ, Hosp Skejby, Aarhus, DenmarkRigshosp, Juliane Marie Ctr, DK-2100 Copenhagen, DenmarkUniv Med Ctr, Dept Pediat Immunol, Utrecht, NetherlandsWilhelmina Childrens Hosp, Utrecht, NetherlandsGreat Ormond St Hosp Sick Children, Children NHS Fdn Trust, Renal Unit, London, EnglandLyon Univ, Hosp Civils Lyon, Rheumatol & Dermatol Dept, Lyon, FranceMed Univ Innsbruck, A-6020 Innsbruck, AustriaPrim Univ Doz, Bregenz, AustriaHamburg Ctr Pediat & Adolescence Rheumatol, Hamburg, GermanyAsklepios Clin Sankt, Augustin, GermanyUniv Zurich, Childrens Hosp, Zurich, SwitzerlandAristotle Univ Thessaloniki, Pediat Immunol & Rheumatol Referral Ctr, GR-54006 Thessaloniki, GreeceIsrael Meir Hosp, Kefar Sava, IsraelSanjay Gandhi Postgrad Inst Med Sci, Lucknow, Uttar Pradesh, IndiaSemmelweis Univ, H-1085 Budapest, HungaryAnna Meyer Hosp, Florence, ItalyUniv Siena, Res Ctr System Autoimmune & Autoinflammatory Dis, I-53100 Siena, ItalyUniv Florence, Florence, ItalyOsped Pediat Bambino Gesu, IRCCS, Pediat Rheumatol Unit, Rome, ItalyUniv Genoa Pediat II Reumatol, Ist G Gaslini EULAR, Ctr Excellence Rheumatol, Genoa, ItalyUniv Cattolica Sacro Cuore, Inst Pediat, Rome, ItalyUniv Padua, Dept Pediat, Pediat Rheumatol Unit, Padua, ItalyYokohama City Univ, Sch Med, Yokohama, Kanagawa 232, JapanUniv Estadual Paulista, UNESP, Botucatu, SP, BrazilUniversidade Federal de São Paulo, Dept Pediat, São Paulo, BrazilUniv Estadual Campinas, Dept Med, Campinas, SP, BrazilUniv Fed Rio de Janeiro, Dept Pediat, Rio de Janeiro, BrazilUniv Estado do, Adolescent Hlth Care Unit, Div Pediat Rheumatol, Rio de Janeiro, BrazilUniv São Paulo, Fac Med, Childrens Inst, Dept Pediat,Pediat Rheumatol Unit, São Paulo, BrazilChildrens Inst, Pediat Rheumatol Unit, São Paulo, BrazilClin Pediat I, Cluj Napoca, RomaniaInst Rheumatol, Belgrade, SerbiaUniv Childrens Hosp, Univ Med Ctr Ljubljana, Ljubljana, SloveniaHead Rheumatol Hosp Pedro Elizalde, Buenos Aires, DF, ArgentinaHosp Gen Mexico City, Mexico City, DF, MexicoHosp Infantil Mexico Fed Gomez, Mexico City, DF, MexicoHosp San Juan Dios, Barcelona, SpainHosp Univ Valle Hebron, Barcelona, SpainMt Sinai Med Ctr, New York, NY 10029 USAMt Sinai Med Ctr, Miami Beach, FL 33140 USAComplejo Hosp Univ Ruiz & Paez, Bolivar, VenezuelaHacettepe Univ, Dept Pediat, Ankara, TurkeyIstanbul Univ, Cerrahpasa Med Sch, Istanbul, TurkeyFMF Arthrit Vasculitis & Orphan Dis Res Ctr, Inst Hlth Sci, Ankara, TurkeyUniv Calgary, Dept Pediat, Alberta Childrens Hosp, Res Inst, Calgary, AB T2N 1N4, CanadaUniversidade Federal de São Paulo, Dept Pediat, São Paulo, BrazilWeb of Scienc

BRS FC414: cultivar de feijoeiro-comum com alta produtividade e qualidade comercial indicada para cultivo sob pivô central.

BRS FC414 se destaca pela excelente qualidade comercial dos grãos, possuindo arquitetura ereta e moderada resistência à murcha de Fusarium e a podridões radiculares, possibilitando a utilização em áreas de cultivo sob pivô central. 2) De acordo com o desempenho, BRS FC414 é recomendada para as épocas das águas e da seca na região II (Mato Grosso do Sul, Paraná, Santa Catarina, São Paulo e Rio Grande do Sul); das águas, da seca e de inverno na região I (Goiás, Mato Grosso, Tocantins, Maranhão, Bahia, Espírito Santo, Rio de Janeiro e o Distrito Federal); e para a época das águas na região III (Sergipe, Alagoas, Pernambuco, Rio Grande do Norte, Piauí, Ceará e Paraíba)

BRS FC415: cultivar de feijoeiro-comum carioca com alta produtividade, qualidade comercial, escurecimento lento dos grãos e resistência a patógenos de solo.

Nos últimos anos o mercado brasileiro se tornou cada vez mais exigente quanto às características de qualidade comercial dos grãos, como o rendimento de peneira, a massa de 100 grãos e a coloração dos grãos. Durante o período entre a colheita e a comercialização dos grãos tipo carioca ocorre o escurecimento da tonalidade bege do tegumento, reduzindo o valor de mercado, porque a coloração mais escura tem menor remuneração, o que pressiona o agricultor para a comercialização rápida, independentemente do preço de mercado

American College of Rheumatology Provisional Criteria for Clinically Relevant Improvement in Children and Adolescents With Childhood-Onset Systemic Lupus Erythematosus

10.1002/acr.23834ARTHRITIS CARE & RESEARCH715579-59

A peregrinação das gestantes no Município do Rio de Janeiro: perfil de óbitos e nascimentos La peregrinación de las gestantes en lo municipio del rio de janeiro: perfil de obitos y nacimiento The peregrination of the pregnants in rio de janeiro city: deaths and births profile

Trata-se de um estudo ecológico. Objetivou-se analisar as trajetórias dos nascimentos no município do Rio de Janeiro e identificar a relação entre oferta de serviços de saúde e fluxo de gestantes entre local de residência e a maternidade. Foram utilizados dados dos Sistemas de Informação sobre Mortalidade (SIM) e Nascidos Vivos (SINASC) de 2004. O processamento e mapeamento dos dados foram feitos através do programa TabWin. O SINASC processou 99.042 declarações de nascidos vivos e o SIM processou 1.318 declarações de óbitos em menores de um ano no Município do Rio de Janeiro. Concluiu-se que a possibilidade de intervenção no perfil da mortalidade infantil e materna desloca-se cada vez mais para a esfera dos serviços de saúde, e o acesso à assistência de qualidade tem papel fundamental na determinação da mortalidade. Deve-se investigar a existência de desigualdades no acesso a tais serviços.<br>Tratase de un estudio ecológico que tiene como objetivo analizar las trayectorias de los nacimientos en lo Municipio del Rio de Janeiro y identificar la relación entre oferta de servicios de la salud y del flujo de gestantes entre el lugar de la residencia y la maternidad. Fueron utilizados los datos de los Sistemas de la Información sobre Mortalidad (SIM) y Nacidos Vivos (SINASC) de 2004. El proceso y el mapeamento de los datos fueron hechos a través del programa TabWin. El SINASC procesó 99.042 declaraciones de nacidos vivos y el SIM procesó 1.318 declaraciones de óbitos en menores de un año en lo Municipio del Rio de Janeiro. Concluyese que la posibilidad de intervención en el perfil de la mortalidad infantil y materna dislocase cada vez más para la esfera de los servicios de la salud, y el acceso a la asistencia de calidad tiene papel fundamental en la determinación de la mortalidad, débese, investigar la existencia de desigualdades en el acceso a tales servicios.<br>This ecological study presented analyze of the birth pathways in the Rio de Janeiro City and identification of the relationship between the health services offer and pregnant flow between their households and the maternity. It was used the data available in the Mortality Information System (MIS) and Live Birth Information System (LBIS) in 2004. The TabWin program processed the data and drew the maps. The LBIS processed 99,042 declarations of live birth and MIS processed 1,318 declarations of deaths in less than one year old in the Rio Janeiro City. The conclusion was that the possibility of intervention in the infantile and maternal mortality profile has happened at the health services, and the access to the quality assistance has fundamental hole in the mortality determination. The existence of access inequalities to the services must be investigated