Analytical and experimental study of electrical conductivity in the lithium tantalate nonstoichiometric structure

We have been interested to experimental and analytical studies of ionic conductivity of nonstoichiometric LiTaO3 solid solutions. Theoretical approach combined with lithium and tantalate vacancy models has been performed. A comparative study between the calculated and measured values is presented taking into account the temperature and composition effects on the conductivity.We have been interested to experimental and analytical studies of ionic conductivity of nonstoichiometric LiTaO3 solid solutions. Theoretical approach combined with lithium and tantalate vacancy models has been performed. A comparative study between the calculated and measured values is presented taking into account the temperature and composition effects on the conductivity

Analyse fractale par morceaux de radiographies osseuses

- L'objectif de cette étude est de proposer, à partir du mouvement brownien fractionnaire (fBm) de paramètre H, un modèle plus général qui puisse englober des phénomènes présentant un caractère fractal par morceaux lors d'une analyse en fréquence. Ce nouveau modèle est appelé pfBm de paramètres Ho en basse fréquence, Hi en haute fréquence, ces deux régimes étant séparés par une fréquence de coupure γ. Pour Ho=Hi=H, le pfBm se réduit au fBm, lui même étant le mouvement brownien pour H=0.5. Nous pensons que le pfBm fournit ainsi un outil plus flexible que le fBm pour l'expérimentateur. Nous avons montré que ce processus a des incréments stationnaires et qu'il est autosimilaire de paramètre Ho pour les basses fréquences et de paramètre Hi pour les hautes fréquences. Nous avons alors étudié des radiographies trabéculaires osseuses qui présentent ce caractère bifractal. Les résultats montrent que l'analyse fractale par morceaux est plus efficace que l'analyse fractale standard pour diagnostiquer les modifications de la micro-architecture osseuse liées à l'ostéoporose

Caractérisation de milieux poreux par étude de leur géométrie 3D : Application à l'os trabéculaire

Cette communication présente le développement d'un ensemble d'outils permettant de caractériser un milieu poreux tel que l'os trabéculaire. Ce travail est basé sur une nouvelle technique permettant de localiser et d'individualiser les arches du milieu poreux. Nous nous intéressons principalement à la mesure d'anisotropie en 3 dimensions et au calcul d'indices d'orientation et de courbure pour chaque travée. Les différentes techniques mises en place sont comparées sur 2 populations différentes composées d'échantillons osseux ostéoporotiques et coxarthriques. Nous montrons que seuls les indices de courbure des travées permettent de discriminer de manière significative les 2 populations étudiées

Polya's inequalities, global uniform integrability and the size of plurisubharmonic lemniscates

First we prove a new inequality comparing uniformly the relative volume of a Borel subset with respect to any given complex euclidean ball \B \sub \C^n with its relative logarithmic capacity in \C^n with respect to the same ball \B. An analoguous comparison inequality for Borel subsets of euclidean balls of any generic real subspace of \C^n is also proved. Then we give several interesting applications of these inequalities. First we obtain sharp uniform estimates on the relative size of \psh lemniscates associated to the Lelong class of \psh functions of logarithmic singularities at infinity on \C^n as well as the Cegrell class of \psh functions of bounded Monge-Amp\`ere mass on a hyperconvex domain \W \Sub \C^n. Then we also deduce new results on the global behaviour of both the Lelong class and the Cegrell class of \psh functions.Comment: 25 page

Relation entre la régularité de fractals 3D et celle de leurs projections 2D. Application à l'os trabéculaire

Deux des auteurs ont récemment établi que la régularité Rn d'un fractal continu isotrope de dimension n (nD) est égale à celle sa projection Rn-1 dans un espace (n-1)D diminuée de 0.5, ou plus clairement, Rn = Rn-1 - 0.5. Dans un premier temps, l'objectif de cette étude est d'expliquer brièvement ce résultat et de l'illustrer sur des volumes fractals synthétiques, continus et binaires, et leurs projections. Pour les fractals continus, les résultats sont proches de eux qu'il convient de trouver pour H faible. Pour H élevé, il apparaît des difficultés liées essentiellement aux défauts de la méthode de synthèse retenue. Pour les fractals binaires, l'écart de 0.5 qu'il est possible de trouver entre la régularité du volume et celle de sa projection n'est pas clairement établie. Dans un deuxième temps, nous avons expérimentalement étudié si cette relation est valide pour l'os trabéculaire et sa projection. Nous avons analysé 22 échantillons de tête de fémur imagés par micro-scanner. Nous trouvons une différence entre la régularité 2D et celle en 3D de 0.53 ± 0.046. Ceci indique que le la relation qui lie la régularité 3D d'un volume fractal à celle de sa projection s'applique pour cet objet binaire. Une simple mesure 2D permettrait alors de quantifier la structure trabéculaire 3D et pourrait se révéler d'une grande force pour le diagnostic précoce de l'ostéoporose

mRNA accumulation in the Cajal bodies of the diplotene larch microsporocyte

In microsporocytes of the European larch, we demonstrated the presence of several mRNAs in spherical nuclear bodies. In the nuclei of microsporocytes, we observed up to 12 bodies, ranging from 0.5 to 6 μm in diameter, during the prophase of the first meiotic division. Our previous studies revealed the presence of polyadenylated RNA (poly(A) RNA) in these bodies, but did not confirm the presence of nascent transcripts or splicing factors of the SR family. The lack of these molecules precludes the bodies from being the sites of synthesis and early maturation of primary transcripts (Kołowerzo et al., Protoplasma 236:13–19, 2009). However, the bodies serve as sites for the accumulation of splicing machinery, including the Sm proteins and small nuclear RNAs. Characteristic ultrastructures and the molecular composition of the nuclear bodies, which contain poly(A) RNA, are indicative of Cajal bodies (CBs). Here, we demonstrated the presence of several housekeeping gene transcripts—α-tubulin, pectin methylesterase, peroxidase and catalase, ATPase, and inositol-3-phosphate synthase—in CBs. Additionally, we observed transcripts of the RNA polymerase II subunits RPB2 and RPB10 RNA pol II and the core spliceosome proteins mRNA SmD1, SmD2, and SmE. The co-localization of nascent transcripts and mRNAs indicates that mRNA accumulation/storage, particularly in CBs, occurs in the nucleus of microsporocytes

Gonadectomy in conditions affecting sex development: a registry-based cohort study

Objectives To determine trends in clinical practice for individuals with DSD requiring gonadectomy. Design Retrospective cohort study. Methods Information regarding age at gonadectomy according to diagnosis; reported sex; time of presentation to specialist centre; and location of centre from cases reported to the International DSD Registry and who were over 16 years old in January 2019. Results Data regarding gonadectomy were available in 668 (88%) individuals from 44 centres. Of these, 248 (37%) (median age (range) 24 (17, 75) years) were male and 420 (63%) (median age (range) 26 (16, 86) years) were female. Gonadectomy was reported from 36 centres in 351/668 cases (53%). Females were more likely to undergo gonadectomy (n = 311, P < 0.0001). The indication for gonadectomy was reported in 268 (76%). The most common indication was mitigation of tumour risk in 172 (64%). Variations in the practice of gonadectomy were observed; of the 351 cases from 36 centres, 17 (5%) at 9 centres had undergone gonadectomy before their first presentation to the specialist centre. Median age at gonadectomy of cases from high-income countries and low-/middle-income countries (LMIC) was 13.0 years (0.1, 68) years and 16.5 years (1, 28), respectively (P < 0.0001) with the likelihood of long-term retention of gonads being higher in LMIC countries. Conclusions The likelihood of gonadectomy depends on the underlying diagnosis, sex of rearing and the geographical setting. Clinical benchmarks, which can be studied across all forms of DSD will allow a better understanding of the variation in the practice of gonadectomy

Bing and Neel Syndrome

Introduction. We report the case of a Bing and Neel syndrome revealed by an isolated left ptosis. Case Report. a 57-year-old man was followed up since October 2003 for a typical Waldenström’s macroglobulinemia. A first complete remission was obtained with chlorambucil. In August 2004, he relapsed. A second complete remission was obtained with RFC chemotherapy regimen (rituximab, fludarabine, and cyclophosphamide). In October 2009, the patient presented with an isolated left ptosis revealing a Bing and Neel syndrome. The diagnosis was suspected on MRI and confirmed by the detection in the CSF of a monoclonal IgM similar to the one found in the plasma. A quite good partial remission has been obtained after one course of RDHAP (rituximab, dexamethasone, cytarabine, and cisplatin) and 3 courses of RDHOx (rituximab, dexamethasone, cytarabine, and oxaliplatin), in addition to ten intrahectal chemotherapy injections. The treatment was followed by intensification and autologous stem cell transplantation. At D58, the patient died due to a septic shock. Conclusion. BNS is a rare and potentially treatable complication of WM. It should be considered in patients with neurologic symptoms and a history of WM

Analytical and experimental study of electrical conductivity in the lithium tantalate nonstoichiometric structure

We have been interested to experimental and analytical studies of ionic conductivity of nonstoichiometric LiTaO 3 solid solutions. Theoretical approach combined with lithium and tantalate vacancy models has been performed. A comparative study between the calculated and measured values is presented taking into account the temperature and composition effects on the conductivity. I