Uni-directional polymerization leading to homochirality in the RNA world

The differences between uni-directional and bi-directional polymerization are considered. The uni-directional case is discussed in the framework of the RNA world. Similar to earlier models of this type, where polymerization was assumed to proceed in a bi-directional fashion (presumed to be relevant to peptide nucleic acids), left-handed and right-handed monomers are produced via an autocatalysis from an achiral substrate. The details of the bifurcation from a racemic solution to a homochiral state of either handedness is shown to be remarkably independent of whether the polymerization in uni-directional or bi-directional. Slightly larger differences are seen when dissociation is allowed and the dissociation fragments are being recycled into the achiral substrate.Comment: 9 pages, 4 figures, submitted to Astrobiolog

Dust grain properties in atmospheres of AGB stars

We present self-consistent dynamical models for dust driven winds of carbon-rich AGB stars. The models are based on the coupled system of frequency-dependent radiation hydrodynamics and time-dependent dust formation. We investigate in detail how the wind properties of the models are influenced by the micro-physical properties of the dust grains that enter as parameters. The models are now at a level where it is necessary to be quantitatively consistent when choosing the dust properties that enters as input into the models. At our current level of sophistication the choice of dust parameters is significant for the derived outflow velocity, the degree of condensation and the estimated mass loss rates of the models. In the transition between models with and without mass-loss the choice ofmicro-physical parameters turns out to be very significant for whether a particular set of stellar parameters will give rise to a dust-driven mass loss or not.Comment: 10 pages, 3 figures. To appear in: Modelling of Stellar Atmospheres, N.E. Piskunov, W.W. Weiss, D.F. Gray (eds.), IAU Symposium Vol. xxx. Proceedings for the IAU Symposium 210, Uppsala, June 200

The influence of dust properties on the mass loss in pulsating AGB stars

We are currently studying carbon based dust types of relevance for carbon-rich AGB stars, to obtain a better understanding of the influence of the optical and chemical properties of the grains on the mass loss of the star. An investigation of the complex interplay between hydrodynamics,radiative transfer and chemistry has to be based on a better knowledge of the micro-physics of the relevant dust species.Comment: 4 pages, 2 figures. Proceedings for IAU Colloquium 185 "Radial and Nonradial Pulsations as Probes of Stellar Physics

Synthetic Line Profiles for Pulsating Red Giants

Pulsation influences atmospheric structures of variable AGB stars (Miras) considerably. Spectral lines of the CO dv=3 vibration-rotation bands (at 1.6mue) therefore have a very characteristic appearance in time series of high-resolution spectra. Coupled to the light cycle they can be observed blue- or red-shifted, for some phases even line doubling is found. This is being explained by radial pulsations and shock fronts emerging in the atmospheres. Based on dynamic model atmospheres synthetic CO line profiles were calculated consistently, reproducing this scenario qualitatively.Comment: 4 pages, 2 figures, to be published in: Proc. of ESO Workshop "High-resolution IR spectroscopy in Astronomy", ed. H.U. Kaeufl, R. Siebenmorgen, A. Moorwood, ESO Astrophysics Symposia, Springer, p.283 added/changed references corrected typ

Three-component modeling of C-rich AGB star winds. II. The effects of drift in long-period variables

We present three-component wind models for carbon rich pulsating AGB stars. In particular we study the effects of drift in models of long-period variables, meaning that the dust is allowed to move relative to the gas (drift models). In addition we investigate the importance of the degree of variability of the wind structures. The wind model contains separate conservation laws for each of the three components of gas, dust and the radiation field. We use two different representations for the gas opacity, resulting in models with different gas densities in the wind. The effects which we investigate here are important for the understanding of the wind mechanism and mass loss of AGB stars. This study is hereby a necessary step towards more reliable interpretations of observations. We find that the effects of drift generally are significant. They cannot be predicted from models calculated without drift. Moreover, the non-drift models showing the lowest mass loss rates, outflow velocities, and the smallest variability in the degree of condensation do not form drift model winds. The wind formation in drift models is, except for a few cases, generally less efficient and the mass loss consequently lower than in the corresponding non-drift models. The effects of drift are generally larger in the more realistic models using that representation of the gas opacity which results in lower densities. The outflow properties of these models are also -- for all cases we have studied -- sensitive to the period of the stellar pulsations. A check of the mass loss rates against a (recent) fit formula shows systematically lower values, in particular in the more realistic models with a low density. The fit is in its current form inapplicable to the new models presented here.Comment: 19 pages, 8 figures, accepted by A&

The Spitzer Spectroscopic Survey of S-type Stars

S-type AGB stars are thought to be in the transitional phase between M-type and C-type AGB stars. Because of their peculiar chemical composition, one may expect a strong influence of the stellar C/O ratio on the molecular chemistry and the mineralogy of the circumstellar dust. In this paper, we present a large sample of 87 intrinsic galactic S-type AGB stars, observed at infrared wavelengths with the Spitzer Space Telescope, and supplemented with ground-based optical data. On the one hand, we derive the stellar parameters from the optical spectroscopy and photometry, using a grid of model atmospheres. On the other, we decompose the infrared spectra to quantify the flux-contributions from the different dust species. Finally, we compare the independently determined stellar parameters and dust properties. For the stars without significant dust emission, we detect a strict relation between the presence of SiS absorption in the Spitzer spectra and the C/O ratio of the stellar atmosphere. These absorption bands can thus be used as an additional diagnostic for the C/O ratio. For stars with significant dust emission, we define three groups, based on the relative contribution of certain dust species to the infrared flux. We find a strong link between group-membership and C/O ratio. We show that these groups can be explained by assuming that the dust-condensation can be cut short before silicates are produced, while the remaining free atoms and molecules can then form the observed magnesium sulfides or the carriers of the unidentified 13 and 20 micron features. Finally, we present the detection of emission features attributed to molecules and dust characteristic to C-type stars, such as molecular SiS, hydrocarbons and magnesium sulfide grains. We show that we often detect magnesium sulfides together with molecular SiS and we propose that it is formed by a reaction of SiS molecules with Mg.Comment: Accepted for publication in A&

Myocardial Tissue Remodeling in Adolescent Obesity

Background: Childhood obesity is a significant risk factor for cardiovascular disease in adulthood. Although ventricular remodeling has been reported in obese youth, early tissue‐level markers within the myocardium that precede organ‐level alterations have not been described. Methods and Results: We studied 21 obese adolescents (mean age, 17.7±2.6 years; mean body mass index [BMI], 41.9±9.5 kg/m2, including 11 patients with type 2 diabetes [T2D]) and 12 healthy volunteers (age, 15.1±4.5 years; BMI, 20.1±3.5 kg/m2) using biomarkers of cardiometabolic risk and cardiac magnetic resonance imaging (CMR) to phenotype cardiac structure, function, and interstitial matrix remodeling by standard techniques. Although left ventricular ejection fraction and left atrial volumes were similar in healthy volunteers and obese patients (and within normal body size‐adjusted limits), interstitial matrix expansion by CMR extracellular volume fraction (ECV) was significantly different between healthy volunteers (median, 0.264; interquartile range [IQR], 0.253 to 0.271), obese adolescents without T2D (median, 0.328; IQR, 0.278 to 0.345), and obese adolescents with T2D (median, 0.376; IQR, 0.336 to 0.407; P=0.0001). ECV was associated with BMI for the entire population (r=0.58, P<0.001) and with high‐sensitivity C‐reactive protein (r=0.47, P<0.05), serum triglycerides (r=0.51, P<0.05), and hemoglobin A1c (r=0.76, P<0.0001) in the obese stratum. Conclusions: Obese adolescents (particularly those with T2D) have subclinical alterations in myocardial tissue architecture associated with inflammation and insulin resistance. These alterations precede significant left ventricular hypertrophy or decreased cardiac function