Architecture and engineering of a supramolecular functional material by manipulating the nano-structure of fiber network

Three-dimensional fiber networks were created from an organogel system consisting mainly of elongated fibrils by using a nonionic surfactant as an additive. The presence of the surfactant molecules manipulates the network structure by enhancing the mismatch nucleation on the growing fiber tips. Both the fiber network structure and the rheological properties of the material can be finely tuned by changing the surfactant concentration, which provides a robust approach to the engineering of supramolecular soft functional materials.<br /

Towards a rhizomatic understanding of the desistance journey

Although the ‘desistance as a (zigzag) journey’ metaphor has proved useful in terms of translating theory into practice, this article makes the case that it is insufficient for conveying the truly complex, social, unpredictable and ‘messy’ process of desistance from crime. The article uses what we know about the process of desistance to discuss the utility of Deleuze and Guattari’s (2013) rhizomatic theory in recasting the desistance journey metaphor. In doing so it is suggested that the desistance journey should be understood in terms of its endless and multiplicitous nature, a symbol of metamorphosis, and it argues that our focus should be on understanding the ‘desister as nomad’. This, the article concludes, holds important ramifications for the way in which we understand and implement desistance-focused practice in the criminal justice system

Starting to Stop: Young Offenders' Desistance from Crime

This paper explores the complexities of the interplay between structural and agentic changes in 21 young offenders' lives as they start to stop offending. The young people's ability to desist from crime was dependent upon their engagement with a 'hook for change', their development of prosocial relationships and 'knifing off' of elements of their offending past, the extent of their identity change, and their confidence about desistance. Desistance was less likely in the absence of a 'hook' and where offenders were running a 'condemnation script'. The study challenges previous research that argues that desistance from crime in adolescence is unlikely

Genetically determined height and coronary artery disease.

BACKGROUND: The nature and underlying mechanisms of an inverse association between adult height and the risk of coronary artery disease (CAD) are unclear. METHODS: We used a genetic approach to investigate the association between height and CAD, using 180 height-associated genetic variants. We tested the association between a change in genetically determined height of 1 SD (6.5 cm) with the risk of CAD in 65,066 cases and 128,383 controls. Using individual-level genotype data from 18,249 persons, we also examined the risk of CAD associated with the presence of various numbers of height-associated alleles. To identify putative mechanisms, we analyzed whether genetically determined height was associated with known cardiovascular risk factors and performed a pathway analysis of the height-associated genes. RESULTS: We observed a relative increase of 13.5% (95% confidence interval [CI], 5.4 to 22.1; P<0.001) in the risk of CAD per 1-SD decrease in genetically determined height. There was a graded relationship between the presence of an increased number of height-raising variants and a reduced risk of CAD (odds ratio for height quartile 4 versus quartile 1, 0.74; 95% CI, 0.68 to 0.84; P<0.001). Of the 12 risk factors that we studied, we observed significant associations only with levels of low-density lipoprotein cholesterol and triglycerides (accounting for approximately 30% of the association). We identified several overlapping pathways involving genes associated with both development and atherosclerosis. CONCLUSIONS: There is a primary association between a genetically determined shorter height and an increased risk of CAD, a link that is partly explained by the association between shorter height and an adverse lipid profile. Shared biologic processes that determine achieved height and the development of atherosclerosis may explain some of the association. (Funded by the British Heart Foundation and others.)

Probation, credibility and justice

This paper explores the difficulties that arise for probation agencies or those that deliver community sanctions in developing and maintaining their credibility in prevailing ‘late-modern’ social conditions. It begins by questioning the limits of the pursuit and promise of ‘public protection’ as a source of credibility, and then proceeds to examine the emergence of an alternative strategy – based principally on reparation and ‘payback’ – in Scotland, arguing that these Scottish developments have much to say to the emerging debates in England and Wales (and elsewhere) about the ‘rehabilitation revolution’ and the proper use of imprisonment. The paper provides a critical account of the development and meaning of the Scottish version of ‘payback’, linking it to some important philosophical and empirical studies that may help to steer the development of payback away from a ‘merely punitive’ drift. In the conclusion, I argue that probation agencies and services need to engage much more deeply and urgently with their roles as justice services, rather than as ‘mere’ crime reduction agencies

The bridge between social identity and community capital on the path to recovery and desistance

It has long been recognised that changes in social networks (and the underpinning changes in personal and social identity) are strong predictors of both desistance from crime and recovery from substance use. Building on existing work attempting to measure and shift social networks and transitions to prosocial groups, the current study provides pilot data from prisoners and family members about a visualisation technique widely used in specialist addiction treatment (node-link mapping) to map opportunities for linkage to prosocial groups and networks. The data presented in the paper are from a small-scale feasibility pilot. This suggests both bonding and bridging capital in prisoner populations due for release and the diversity of community capital opportunities that exists in this population. The implications of this work are significant for substance users and offenders pending return to the community, and has implications around resettlement and reintegration support for probation staff in prisons and in the community. The paper emphasises the importance of mapping connectedness as a key component of planning for reintegration back into the community for those working with offenders who are aspiring to achieve desistance and recovery

Exploring Alternative Terrain in the Rehabilitation and Treatment of Offenders: Findings from a Prison-based Music Project

The arts in prison settings have provided an alternative or complimentary component to rehabilitation. Despite increased interest, studies capturing the voice of offenders participating in projects and the long-term impact are limited. Data from semistructured interviews with 18 men who had taken part in a music-based project while incarcerated, including one group of five participants who were tracked for 18 months with supplemented data from correctional staff and official documentation, is presented. Participants of the art-based projects comment on changes they believe to have derived from participating in the project, particularly relating to emotions, self-esteem, self-confidence, communication and social skills. An exoffender sample of participants reported that participation in art projects provide experiences that promote beneficial skills that have been useful for post prison life

A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease

Existing knowledge of genetic variants affecting risk of coronary artery disease (CAD) is largely based on genome-wide association studies (GWAS) analysis of common SNPs. Leveraging phased haplotypes from the 1000 Genomes Project, we report a GWAS meta-analysis of 185 thousand CAD cases and controls, interrogating 6.7 million common (MAF>0.05) as well as 2.7 million low frequency (0.005<MAF<0.05) variants. In addition to confirmation of most known CAD loci, we identified 10 novel loci, eight additive and two recessive, that contain candidate genes that newly implicate biological processes in vessel walls. We observed intra-locus allelic heterogeneity but little evidence of low frequency variants with larger effects and no evidence of synthetic association. Our analysis provides a comprehensive survey of the fine genetic architecture of CAD showing that genetic susceptibility to this common disease is largely determined by common SNPs of small effect siz

The process of primary desistance from intimate partner violence

This study examined the interaction between structure and agency for individuals in the first or early phase of primary desistance (one year offending free) from intimate partner violence (IPV). Narrative accounts of perpetrators, survivors and IPV programme facilitators were analysed using Thematic Analysis. Changes in the self and the contexts, structures and conditions were necessary to promote desistance. Perpetrators made behavioural and cognitive changes taking on different identities (agentic role) by removing external stressors and instability within the confines of a supportive environment (structural role). Findings provide a theoretical framework of desistance from IPV that integrates social processes and subjective change