2,136 research outputs found

    Concert recording 2017-01-25

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    [Track 1]. Passaggio rotto from Book 2 of Ayres for the violin / Nicola Matteis -- [Tracks 2-4]. Partia #4 in E minor for 2 violins and basso from Muscalsche ergotzung / Johann Pachelbel -- [Track 5]. Partia #5 in G minor from Artifiosus concentur pro camera / Johann Vilsmayr -- [Track 6]. Sonata #4 / Heinrich Biber -- [Tracks 7-9].Sonata for violin and piano, K. 454 / W.A. Mozart -- [Track 10]. The dream, Op. 38 #5 / Serge Rachmaninoff -- [Tracks 11-13]. Sonata for violin and piano #3 in C minor / Edvard Grieg

    Microscopic Current Dynamics in Nanoscale Junctions

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    So far transport properties of nanoscale contacts have been mostly studied within the static scattering approach. The electron dynamics and the transient behavior of current flow, however, remain poorly understood. We present a numerical study of microscopic current flow dynamics in nanoscale quantum point contacts. We employ an approach that combines a microcanonical picture of transport with time-dependent density-functional theory. We carry out atomic and jellium model calculations to show that the time evolution of the current flow exhibits several noteworthy features, such as nonlaminarity and edge flow. We attribute these features to the interaction of the electron fluid with the ionic lattice, to the existence of pressure gradients in the fluid, and to the transient dynamical formation of surface charges at the nanocontact-electrode interfaces. Our results suggest that quantum transport systems exhibit hydrodynamical characteristics which resemble those of a classical liquid.Comment: 8 pages, 5 figures; Accepted for publication in Phys. Rev.

    Investigating The Life Cycle Of Haplosporidium nelsoni (MSX)

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    Attempts to decipher the life cycle of Haplosporidium nelsoni began almost immediately after it was identified as the pathogen causing MSX disease in eastern oysters, Crassostrea virginica. But transmission experiments failed and the spore stage, characteristic of haplosporidans, was extremely rare. Researchers concluded that another host was involved: an intermediate host in which part of the life cycle was produced, or-if the oyster was an accidental host-an alternate host that produces infective elements. A later finding that spores were found more often in spat (\u3c 1 y old) than in adults revived the idea of direct transmission between oysters. The new findings and the availability of molecular diagnostics led us to revive life cycle investigations. Over several years, oyster spat were examined for spores and searched for H. nelsoni in potential non-oyster hosts using both histological and polymerase chain reaction (PCR) methodologies. Although spores occurred in a high proportion of spat with advanced infections, it was concluded that they were unlikely to be a principal source of infective elements because naive oysters used as sentinels to assess infection pressure became highly infected even after native oysters developed resistance, and infected spat could no longer be found. A histological survey of zooplankton and small bivalves in Delaware Bay found few recognizable parasites and nothing resembling a haplosporidan. A subsequent PCR study of water, sediment, and macro-invertebrates from Chesapeake, Delaware, and Oyster bays resulted in many positive samples, but in situ hybridization failed to identify any recognizable structures. PCR analysis of potential intermediate hosts for other molluscan pathogens has also resulted in many species yielding positive results but required in situ hybridization to verify infections. It is suggested that any future search for a nonoyster host of H. nelsoni be conducted in a relatively confined system and/or target specific phyla, strategies that have been successful in other life cycle studies. It is noted that candidate phyla could include those known to host haplosporidans and species whose abundance or distribution may have changed in concert with outbreaks of MSX disease in the northeastern United States in recent years

    Multifluorescence High‐Resolution Episcopic Microscopy for 3D Imaging of Adult Murine Organs

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    3D microscopy of large biological samples (>0.5 cm^{3})is transforming biological research. Many existing techniques require trade-offs between image resolution, sample size, and method complexity. A simple robust instrument with the potential to conduct large-volume 3D imaging currently exists in the form of the optical high-resolution episcopic microscopy (HREM). However, the development of the instrument to date is limited to single-fluorescent wavelength imaging with nonspecific eosin staining. Herein, developments to realize the potential of the HREM to become multifluorescent high-resolution episcopic microscopy (MF-HREM) are presented. MF-HREM is a serial-sectioning and block-facing wide-field fluorescence imaging technique, which does not require tissue clearing or optical sectioning. Multiple developments are detailed in sample preparation and image postprocessing to enable multiple specific stains in large samples and show how these enable segmentation and quantification of the data. The application of MF-HREM is demonstrated in a variety of biological contexts: 3D imaging of whole tumor vascular networks and tumor cell invasion in xenograft tumors up to 7.5 mm^{3} at resolutions of 2.75 Όm, quantification of glomeruli volume in the adult mouse kidney, and quantification of vascular networks and white-matter track orientation in adult mouse brain

    Photodynamic Therapy Treatment for Eyes with Drusenoid Pigment Epithelium Detachment

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    We report the clinical course of photodynamic therapy (PDT) in a patient with drusenoid pigment epithelium detachment (PED). A patient with drusenoid PED underwent PDT follow-up was carried out at one week, one month, three months, six months and one year after treatment. Fundus exam, optical coherence tomography (OCT) and fluorescein angiography were performed. After the PDT, drusen and PED were gradually diminished over one year. However, pure serous PED eventually developed at the same location of the drusenoid PED. The results of the PDT, on drusenoid PED, were initially effective, but not completely successful. Therefore, PDT may be considered as an alternative treatment option for drusenoid PED

    Creating Awareness of Sleep-Wake Hours by Gamification

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    This book constitutes the refereed proceedings of the 11th International Conference on Persuasive Technology, PERSUASIVE 2016, held in Salzburg, Austria, in April 2016

    A content analysis of airline mission statements: Changing trends and contemporary components

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    Mission statements have an important bearing on business and in the airline industry such statements inform and connect international and heterogeneous stakeholders. While research was conducted on airline mission statements over a decade ago, the industry has since been transformed with the rise of new global carriers and changing consumer trends. The purpose of this study is to examine current airline mission statements to update findings from previous studies. The analysis evaluates the content of mission statements from 79 passenger airlines from around the world. The outcomes reveal products/services, customers, and location/markets as the three most prevalent components. Additionally, it appears mentions of safety in mission statements are increasingly apparent as airlines seek to ensure trust and confidence among consumers. The results and conclusions build on a framework of ten mission statement components and make comparisons between airlines and regions of the world

    Multilevel surgery for children with cerebral palsy: A meta-analysis

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    Funding to conduct this review was received from RCSI’s Research Summer School programme

    Segregation of Mn, Si, Al, and oxygen during the friction stir welding of DH36 steel

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    This work investigates the role of welding speed in elemental segregation of Mn, Si, Al, and oxygen during friction stir welding (FSW) in DH36 steel. The experimental work undertaken showed that when the speed of the FSW process exceeds 500 RPM with a traverse speed of 400 mm/min, then elemental segregation of Mn, Si, Al, and O occurred. The mechanism of this segregation is not fully understood; additionally, the presence of oxygen within these segregated elements needs investigation. This work examines the elemental segregation within DH36 steel by conducting heat treatment experiments on unwelded samples incrementally in the range of 1200–1500 °C and at cooling rates similar to that in FSW process. The results of heat treatments were compared with samples welded under two extremes of weld tool speeds, namely W1 low tool speeds (200 RPM with traverse speed of 100 mm/min) and W2 high tool speeds (550 RPM with traverse speed of 400 mm/min). The results from the heat treatment trials showed that segregation commences when the temperature exceeds 1400 °C and Mn, Si, Al, and oxygen segregation progress occurs at 1450 °C and at a cooling rate associated with acicular ferrite formation. It was also found that high rotational speeds exceeding 500 RPM caused localized melting at the advancing-trailing side of the friction stir-welded samples. The study aims to estimate peak temperature limits at which elemental segregation does not occur and hence prevent their occurrence in practice by applying the findings to the tool’s rotational and traverse speed that correspond to the defined temperature

    Establishing non-thermal regimes in pump-probe electron-relaxation dynamics

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    Time- and angle-resolved photoemission spectroscopy (TR-ARPES) accesses the electronic structure of solids under optical excitation, and is a powerful technique for studying the coupling between electrons and collective modes. One approach to infer electron-boson coupling is through the relaxation dynamics of optically-excited electrons, and the characteristic timescales of energy redistribution. A common description of electron relaxation dynamics is through the effective electronic temperature. Such a description requires that thermodynamic quantities are well-defined, an assumption that is generally violated at early delays. Additionally, precise estimation of the non-thermal window -- within which effective temperature models may not be applied -- is challenging. We perform TR-ARPES on graphite and show that Boltzmann rate equations can be used to calculate the time-dependent electronic occupation function, and reproduce experimental features given by non-thermal electron occupation. Using this model, we define a quantitative measure of non-thermal electron occupation and use it to define distinct phases of electron relaxation in the fluence-delay phase space. More generally, this approach can be used to inform the non-thermal-to-thermal crossover in pump-probe experiments.Comment: 18 pages, 10 figure
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