18 research outputs found

    La enseñanza de la lengua de signos en el Espacio Europeo de Educación Superior: Adaptaciones al Marco Común Europeo de Referencia para las Lenguas

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    La red de investigación que, desde la Universidad de Alicante, analiza la enseñanza de la lengua de signos española (LSE) en el marco del Espacio Europeo de Educación Superior (EEES), se ha articulado en torno a tres ejes: la propia enseñanza de la lengua y la cultura de la Comunidad Sorda española en el ámbito universitario y, más concretamente, en la Universidad de Alicante; el aprendizaje por parte del alumnado que ha cursado esta materia, y el papel de las intérpretes de lengua de signos que desarrollan su labor en este contexto. En los tres casos, presentamos la investigación que hemos llevado a cabo desde la red gracias a la colaboración de profesorado, alumnado e intérpretes, y que supone una completa panorámica de la situación actual de la LSE en el EEES. Una de las principales conclusiones es la necesidad de armonizar su enseñanza bajo las directrices europeas de enseñanza de idiomas que dicta el Marco Común Europeo de Referencia para las Lenguas (MCER, 2001), lo cual presupone una estandarización lingüística de la LSE que aún está en vías de desarrollo

    Post-mortem findings in Spanish patients with COVID-19; a special focus on superinfections

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    IntroductionWhole-body autopsies may be crucial to understand coronavirus disease 2019 (COVID-19) pathophysiology. We aimed to analyze pathological findings in a large series of full-body autopsies, with a special focus on superinfections. MethodsThis was a prospective multicenter study that included 70 COVID-19 autopsies performed between April 2020 and February 2021. Epidemiological, clinical and pathological information was collected using a standardized case report form. ResultsMedian (IQR) age was 70 (range 63.75-74.25) years and 76% of cases were males. Most patients (90%,) had at least one comorbidity prior to COVID-19 diagnosis, with vascular risk factors being the most frequent. Infectious complications were developed by 65.71% of the patients during their follow-up. Mechanical ventilation was required in most patients (75.71%) and was mainly invasive. In multivariate analyses, length of hospital stay and invasive mechanical ventilation were significantly associated with infections (p = 0.036 and p = 0.013, respectively). Necropsy findings revealed diffuse alveolar damage in the lungs, left ventricular hypertrophy in the heart, liver steatosis and pre-infection arteriosclerosis in the heart and kidneys. ConclusionOur study confirms the main necropsy histopathological findings attributed to COVID-19 in a large patient series, while underlining the importance of both comorbid conditions and superinfections in the pathology

    Lack of associations of microRNAs with severe NAFLD in people living with HIV: discovery case-control study

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    Background & objectiveNonalcoholic fatty liver disease (NAFLD) is highly prevalent in people living with HIV (PLWH) and the expression of some microRNAs could be useful as biomarkers for the diagnosis of NAFLD. The aim of this study was to identify patterns of differential expression of microRNAs in PLWH and assess their diagnostic value for NALFD.MethodsA discovery case-control study with PLWH was carried out. The expression of miRNAs was determined using HTG EdgeSeq technology. Cases were defined as patients with severe NAFLD and controls as patients without NAFLD, characterized using the controlled attenuation parameter (CAP). Cases and controls were matched 1:1 for age, sex, BMI, CD4+ lymphocyte count, active HCV infection, and ART regimen.ResultsSerum 2,083 simultaneous microRNA transcripts were analyzed using HTG technology and compared between cases and controls. Forty-five patients, 23 cases, and 22 controls were included in the study. In the analysis of the expression pattern of the 2,083 microRNAs, no differential expression patterns were found between both groups of patients included in the study.ConclusionAnalysis of the microRNA transcriptome profile of nonobese PLWH with severe NAFLD did not appear to differ from that of patients without NAFLD. Thus, microRNA might not serve as a proper biomarker for predicting severe NALFD in this population

    Variables psicológicas implicadas en la actitud e iniciativa emprendedora (II): personalidad, cognición y emoción

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    El proyecto titulado: Variables implicadas en la actitud e iniciativa emprendedora (II): personalidad, cognición y emoción, es la continuidad de otro presentado en la convocatoria anterior (2016-2017) cuyo objetivo era evaluar variables psicológicas en la actitud emprendedora de los estudiantes universitarios de la Universidad Complutense de Madrid (UCM). Este segundo proyecto ha tenido por objetivo principal ampliar la evaluación a otras facultades y áreas de conocimiento de nuestra universidad a fin de obtener el mapa y perfil de la iniciativa emprendedora del universitario UCM

    Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

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    Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

    Post-mortem findings in Spanish patients with COVID-19; a special focus on superinfections

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    Introduction: Whole-body autopsies may be crucial to understand coronavirus disease 2019 (COVID-19) pathophysiology. We aimed to analyze pathological findings in a large series of full-body autopsies, with a special focus on superinfections. Methods: This was a prospective multicenter study that included 70 COVID-19 autopsies performed between April 2020 and February 2021. Epidemiological, clinical and pathological information was collected using a standardized case report form. Results: Median (IQR) age was 70 (range 63.75-74.25) years and 76% of cases were males. Most patients (90%,) had at least one comorbidity prior to COVID-19 diagnosis, with vascular risk factors being the most frequent. Infectious complications were developed by 65.71% of the patients during their follow-up. Mechanical ventilation was required in most patients (75.71%) and was mainly invasive. In multivariate analyses, length of hospital stay and invasive mechanical ventilation were significantly associated with infections (p = 0.036 and p = 0.013, respectively). Necropsy findings revealed diffuse alveolar damage in the lungs, left ventricular hypertrophy in the heart, liver steatosis and pre-infection arteriosclerosis in the heart and kidneys. Conclusion: Our study confirms the main necropsy histopathological findings attributed to COVID-19 in a large patient series, while underlining the importance of both comorbid conditions and superinfections in the pathology.Ministerio de Sanidad (España)Comisión EuropeaMinisterio de Ciencia, Innovación y UniversidadesInstituto de Salud Carlos IIIDepto. de MedicinaFac. de MedicinaTRUEpu

    Returning to the gaybourhood: Expectations of resilience and recovery of Chueca (Madrid) after the COVID-19 pandemic

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    Chueca, in Madrid, is Spain’s most well-known gaybourhood, a significant space for both local and national LGBTQ individuals and activist movements, as well as for the Spanish and European LGBTQ tourist circuits. The COVID- 19 pandemic hit hard in a neighbourhood already heavily disputed among arguments of touristification and tourist accommodation, as tourist-oriented businesses began closing and other, more resident-oriented ones transformed themselves to survive the year 2020. Drawing from ethnographic research undertaken from 2019 to early 2021, this article analyses different experiences and expectations of recovery among local professionals, mostly business- owners from Chueca itself. The opposition between a return to business-as-usual and a revolution towards a more humane or sustainable tourism, on the one hand, and an already conflicted debate over the nature of the neighbourhood, on the other one, interacts with the wider situation of urban tourist destinations in Western Europe and with the practices of discourses unveiled in Chueca. The article argues for the pandemic’s role as a catalyst for pre-existing conflicts, as local and global processes intertwine.Depto. de Antropología Social y Psicología SocialFac. de Ciencias Políticas y SociologíaTRUEpu

    La enseñanza de la lengua de signos en el Espacio Europeo de Educación Superior: Adaptaciones al Marco Común Europeo de Referencia para las Lenguas

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    La red de investigación que, desde la Universidad de Alicante, analiza la enseñanza de la lengua de signos española (LSE) en el marco del Espacio Europeo de Educación Superior (EEES), se ha articulado en torno a tres ejes: la propia enseñanza de la lengua y la cultura de la Comunidad Sorda española en el ámbito universitario y, más concretamente, en la Universidad de Alicante; el aprendizaje por parte del alumnado que ha cursado esta materia, y el papel de las intérpretes de lengua de signos que desarrollan su labor en este contexto. En los tres casos, presentamos la investigación que hemos llevado a cabo desde la red gracias a la colaboración de profesorado, alumnado e intérpretes, y que supone una completa panorámica de la situación actual de la LSE en el EEES. Una de las principales conclusiones es la necesidad de armonizar su enseñanza bajo las directrices europeas de enseñanza de idiomas que dicta el Marco Común Europeo de Referencia para las Lenguas (MCER, 2001), lo cual presupone una estandarización lingüística de la LSE que aún está en vías de desarrollo

    PARTIC : Memoria 2003-04

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    El trabajo no ha sido publicado. Resumen basado en ficha elaborada por los autores. La memoria (electrónica) adjunta está en distinto formato a la impresa (diapositivas del Power Point), pero el contenido es el mismo.El trabajo se realiza en el CEIP Pintor Aguastín Riancho, centro al que pertenecen los 17 profesores que han sido partícipes del proyecto. Los objetivos que se pretenden alcanzar son: posibilitar a los alumnos el uso de las TIC; formar alumnos capaces de utilizar las nuevas tecnologías como una herramienta mas de acceso a la información y al conocimiento; normalizar el uso de las nuevas tecnologías en el colegio; disponer de los avances científicos proporcionados por las nuevas tecnologías; generar juicios críticos (posicionales) sobre la informática. Estos objetivos, se intentan conseguir por medio de la integración del ordenador como recurso de afianzamiento y complemento de los contenidos curriculares de cada área, realizando fichas de evaluación de los programas software por ciclos, y con la formación de la utilización de Internet, direcciones Web, etc. La evaluación de los profesores considera que el proyecto favorece el aprendizaje y disminuye el fracaso escolar, así como fomenta el trabajo en equipo.Consejería de Educación y Juventud de CantabriaCantabriaES

    Table_1_Lack of associations of microRNAs with severe NAFLD in people living with HIV: discovery case-control study.xlsx

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    Background & objectiveNonalcoholic fatty liver disease (NAFLD) is highly prevalent in people living with HIV (PLWH) and the expression of some microRNAs could be useful as biomarkers for the diagnosis of NAFLD. The aim of this study was to identify patterns of differential expression of microRNAs in PLWH and assess their diagnostic value for NALFD.MethodsA discovery case-control study with PLWH was carried out. The expression of miRNAs was determined using HTG EdgeSeq technology. Cases were defined as patients with severe NAFLD and controls as patients without NAFLD, characterized using the controlled attenuation parameter (CAP). Cases and controls were matched 1:1 for age, sex, BMI, CD4+ lymphocyte count, active HCV infection, and ART regimen.ResultsSerum 2,083 simultaneous microRNA transcripts were analyzed using HTG technology and compared between cases and controls. Forty-five patients, 23 cases, and 22 controls were included in the study. In the analysis of the expression pattern of the 2,083 microRNAs, no differential expression patterns were found between both groups of patients included in the study.ConclusionAnalysis of the microRNA transcriptome profile of nonobese PLWH with severe NAFLD did not appear to differ from that of patients without NAFLD. Thus, microRNA might not serve as a proper biomarker for predicting severe NALFD in this population.</p
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