T35: a small automatic telescope for long-term observing campaigns

The T35 is a small telescope (14") equipped with a large format CCD camera installed in the Sierra Nevada Observatory (SNO) in Southern Spain. This telescope will be a useful tool for the detecting and studying pulsating stars, particularly, in open clusters. In this paper, we describe the automation process of the T35 and show also some images taken with the new instrumentation.Comment: 13 pages, 9 figures. Accepted for publication in the special issue "Robotic Astronomy" of Advances of Astronom

Smart Solar Micro-exchangers for Sustainable Mobility of University Camps

Publicado el resumen en: https://www.wmcaus.org/files/WMCAUS2020_Book.pdf. Pendiente de publicación de las contribuciones en IOP Conference Series: Materials Science and Engineering.A significant number of universities have several campuses located in urban or rural settings, or with scattered university buildings that require the use of means of transportation. This implies the mobility and potential displacement of a large community of students, professors and researchers. The use of electric bicycles (e-bikes) is an intermediate alternative between the bicycle and electric cars. It can be an important stimulus for the promotion of the decarbonisation of the University Campus, avoiding the traffic congestion and reducing space requirements for parking. This paper presents the smart solar micro-exchanger model managed through a sustainable mobility web platform, applied to the case study of the University of Malaga (Spain). It is a solar charging station for e-bike, whose design is based on the principles of solar architecture (providing great security to e-bike). It managed by a web platform and app that allows the user to make reservations and learn about the savings in CO2 emissions. The system allows performing an aerobic sports activity without sweating problems when you reach the job. The platform also incorporates a database of quiet and safe routes for e-bike users.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tec

Reseñas de libros

Carrasca Hortal, José y Millán Gómez, Antonio. La Estructura Gótica Catalana. Sobre los conceptos de media y espacio. El problema de la forma en la cubierta (Por Antonio Millán) pp. 4.-- Verd Herrero, Antonio. Dibujo del natural. Manual de texto docente universitario (Por Antonio Verd) pp.5-6.-- Caninva, Luigi. L'Architettura romana (Por Carlos de San Antonio Gómez) pp.6-7.-- Villalobos Alonso, Daniel. La mirada de Fisac (Por Alberto Grijalba Bengoetxea)pp.8.-- Jiménez Martín, Alfonso et al. La catedral gótica de Sevilla. Fundación y fábrica de la obra nueva (Por Enrique Rabasa Díaz) pp.8-9.-- García-Gutiérrez Mosteiro, Javier. Narciso Pascual y Colomer (1808-1870). Arquitecto del Madrid isabelino (Por Enrique Rabasa Díaz) pp.9-10.-- Valladolid. Bellido Blanco, Santiago. Cuaderno de apuntes (Por Fernando Lmares García) pp.10-11.-- Lopez-Peláez, José Manuel. Maestros cercanos de un arquitecto (Por Javier García-Gutiérrez Masteiro) pp.12.-- Garcia Bueno, Antonio. Dibujando la Alhambra (Por Joaquín Casado de Amezúa Vázquez) pp.13-14.-- Chías Navarro, Pilar y Abad Balboa, Tomás. Eduardo Torroja. Obras y proyectos (Por Jorge Llopis Verdú) pp.14-15.-- Gómez i Serrano, Josep y Font, Juan. La forma de la Villa de Madrid. Soporte gráfico para la información histórica de la ciudad (Por Jorge Llopis Verdú) pp.15-16.-- Nagore, Fernando. Geometría métrica y descriptiva para arquitectos (Por José Antonio Ruiz de le Rosa) pp.16-17.-- Rabasa Diaz, Enrique y el Centro de los Oficios de LeónGuía práctica de la estereotomía de la piedra (Por José CalvoLópez) pp.18-19.-- Hernández Iviartinez, Ascensión. La clonación arquitectónica (Por José Joaquín Parra 8añón) pp.20-21.-- Gentil Baldrich, José María y Yanguas Álvarez de Toledo, Ana. Fernando Barquín y Barón Joaquín Barquín y Barón Imágenes de su archivo en los fondos FIDAS (Por José Manuel Pala) pp.21-22.-- Escoda Pastor, Carmen. El magnetismo del lugar en la arquitectura pp.23.-- Herrero Vázquez, Eduardo Alejandro. Compases de mano, compases de ojo: la Geometrización de la Realidad según Laussedat (POr Adrien Javary) pp.24-25.-- Castaño Perea, Enrique. Arquitectura y música: Policoralidad en la Capilla Real del Alcázar de Madrid pp.25-26.-- Piquer Cases, Juan Carlos. Los modelos digitales en la arquitectura, desarrollo del proyecto e investigación patrimonial. Palacio Real de Valencia (1239-1810): análisis y reconstrucción virtual sobre la planta de Vicente Gascó de 1761 (Por Juan Carlos Piquer Cases) pp.26-28.-- Pérez Naya, Antonia. Arquitectura del silencio y la memoria. Análisis de los cementerios de la Costa da Morte gallega (Por JAfT) pp. 28-29.-- Falcón Meraz, José Manuel. La expresión de una línea museística singular (Por Juan Puebla) pp.29-30.-- 11Seminario Internacional "Color en el Diseño y la Arquitectura" pp.32.-- Taller de Pintura con Antonio López E.T.S. de Pamplona, septiembre de 2006 y 2007 (Por Inmacu/ada .liméne: Cabal/ero) pp.32-35.-- Arquitectura y autopsia: análisis gráficos de algunos restos de la inexistente Universidad laboral de Sevilla (Por José Joaquín Parra Bañón) pp.36-37Milán Gómez, A.; Verd Herrero, A.; De San Antonio Gomez, JC.; Grijalba Bengoetxea, A.; Rabasa Díaz, E.; Linares García, F.; García-Gutiérrez Mosteiro, J.... (2008). Reseñas de libros. EGA Expresión Gráfica Arquitectónica. 13(13):4-37. https://doi.org/10.4995/ega.2008.10266OJS437131

Reseñas de libros

Granero Martín, Francisco. Agua y ciudad, Análisis de estratégias y procesos de planificación. Quince a diecinueve (Por José Mª Gentil Baldrich), pp. 4-5.-- Parra Bañón, José Joaquín. Pensamiento arquitectónico na obra de José Saramago. Acerca da arquitectura da casa (Por José Mª Gentil Baldrich) pp. 5-6.-- Gentil Baldrich, ]osep María, Yanguas Álvarez de Toledo, Ana. Rito V Fiesta: Una aproximación a la arquitectura efímera sevillana (Por Javier García-Gutiérrez Mosteiro) pp. 7-8.-- Puebla Pons, Juan. La plástica del espacio (Por Josep Maria Montaner y Joan Fontbernat) pp. 8.-- Gómez-Blanco Pontes, Antonio J. Dibujar Granada. La Gran Vía de Colón Por Joaquín Casado de Amezúa) pp.9.-- Almagro Gorbea, Antonio. Levantamiento arquitectónico (Por Joaquín Casado de Amezúa) pp.9-10.-- Villalobos Alonso, Daniel. Hasta los pies del Himalaya. Cuaderno de dibujos de Viaje (Por Fernando Linares García) pp. 10-11.-- Fernández Martín,J.J., et. al. Las ruinas de Dios. Arquitectura olvidada en la provincia de Valladolid (Por Fernando Linares García) pp.11.12.-- Delgado Yanes, Magali y Redondo Domínguez, Ernest, Dibujo a mano alzada para arquitectos (Por Lluís Villanueva Bartrina) pp.13-14.-- Edición digital del libro de actas del IX Congreso EGA pp.14.-- Costa Buján, Pablo y Franco Taboada, José Antonio. Análisis gráfico y propuestas de intervención en puertos de Galicia pp.15.-- Franco Taboada, José Antonio, Tarrío Carrodeguas, Santiago. El conjunto catedralicio de Tuy.Documentación Gráfica pp.16.-- Solana Suárez, Enrique, et. al. Crisis del barrio tradicional: ruptura, mutación o continuidad (Por Luis Doreste Chirino) pp.17.-- Bellido Blanco, D. Santiago. El río Duero. Influencia del entorno natural en la conformación del paisaje humanizado pp.18-19.-- Higón Calvet, José Luis. Contribuciones al estudio del asoleo geométrico. Procedimientos para el cálculo del factor de obstrucción solar. Aplicaciones p.19-20.-- Linares Garcia, Fernando. La arquitectura de las Brañas de Somiedo -Asturias- pp.20-21.-- Martínez Ivars, Carlos Salvador. El dibujo arquitectónico en la construcción de la ciudad de Alicante: Del derribo de las murallas a los años treinta pp.21-22.-- Gutiérrez Labory, Eisa Ma. Le Corbusier, el control geométrico matemático de la forma pp22.-- Martín-González Armingol, Manuel. Mies van Der Rohe: Recursos expresivos y elementos arquitectónicos, a través de los archivos depositados en el Museo de Arte Moderno de New York pp.23-24.-- Mata Botella, Elena. El análisis gráfico de la casa pp.24-27.-- Los pabellones españoles en las exposiciones universales e internacionales a partir de 1937 pp.27.-- El ininterrumpido dibujar de Javier Seguí (Por Javier García-Gutiérrez Mosteiro) pp.28.29.-- X Congreso Internacional de Expresión Gráfica Arquitectónica (por Joaquín Casado de Amezúa, Antonio Gómez-Blanco Pontes) pp.29.-- IV Jornadas de Fotogrametría Arquitectónica (Por Jesús San José Alonso) pp.30.-- Dibujos del Alcázar de Sevilla (Por José A. Ruiz de la Rosa) pp.30-31.-- Miguel García Lisón (Por Juan Puebla Pons) pp.32.-- Cándido Orts Bayarri (Por Rafael Contel Comenge) pp.32.-- José Ignacio González Moreno (Por Carmen García Reig) pp.33.-- Julio Vidaurre Jofre (Por Enrique Rabasa Díaz) pp.33.-- Santiago Roqueta (Por Javier Monedero) pp.34Gentil Baldrich, JM.; García- Gutiérrez Mosteiro, J.; Montaner, JM.; Fontbernat, J.; Casado De Amezúa, J.; Linares García, F.; Villanueva Bartrina, L.... (2005). Reseñas de libros. EGA Expresión Gráfica Arquitectónica. 10(10):4-35. https://doi.org/10.4995/ega.2005.10327OJS435101

Novel deep targeted sequencing method for minimal residual disease monitoring in acute myeloid leukemia

A high proportion of patients with acute myeloid leukemia who achieve minimal residual disease (MRD) negative status ultimately relapse because a fraction of pathological clones remains undetected by standard methods. We designed and validated a high-throughput sequencing method for MRD assessment of cell clonotypes with mutations of NPM1, IDH1/2 and/or FLT3-SNVs. For clinical validation, 106 follow-up samples from 63 patients in complete remission were studied by NGS, evaluating the level of mutations detected at diagnosis. The predictive value of MRD status by NGS, multiparameter flow cytometry, or quantitative PCR was determined by survival analysis. The method achieved a sensitivity of 10-4 for SNV mutations and 10-5 for insertions/deletions and could be used in acute myeloid leukemia patients who carry any mutation (86% in our diagnosis data set). NGS-determined MRD positive status was associated with lower disease-free survival (hazard ratio [HR] 3.4, p=0.005) and lower overall survival (HR 4.2, p<0.001). Multivariate analysis showed that MRD positive status by NGS was an independent factor associated with risk of death (HR 4.54, p =0.005) and the only independent factor conferring risk of relapse (HR 3.76, p =0.012). This NGS based method simplifies and standardizes MRD evaluation, with high applicability in acute myeloid leukemia. It also improves upon flow cytometry and quantitative PCR to predict acute myeloid leukemia outcome and could be incorporated in clinical settings and clinical trials.This study was supported by the Subdirección General de Investigación Sanitaria (Instituto de Salud Carlos III, Spain) grants PI13/02387 and PI16/01530, and the CRIS against Cancer foundation grant 2014/0120. M.L. holds a postdoctoral fellowship of the Spanish Ministry of Economy and Competitiveness (FPDI-2013-16409). P.R.P. holds a postdoctoral fellowship of the Spanish of Instituto de Salud Carlos III: Contrato Predoctoral de Formación en Investigación en Salud i-PFIS (IFI 14/00008).S

Higher versus lower nut consumption and changes in cognitive performance over two years in a population at risk of cognitive decline: a cohort study

Background: Tree nuts and peanuts (henceforth, nuts) are nutrient-dense foods rich in neuroprotective components; thus, their consumption could benefit cognitive health. However, evidence to date is limited and inconsistent regarding the potential benefits of nuts for cognitive function. Objective: To prospectively evaluate the association between nut consumption and 2-y changes in cognitive performance in older adults at cognitive decline risk. Methods: A total of 6,630 participants aged 55 to 75 y (mean age 65.0±4.9 y, 48.4% women) with overweight/obesity and metabolic syndrome completed a validated semi-quantitative food frequency questionnaire and a comprehensive battery of neuropsychological tests at baseline and a 2-y follow-up. Composite cognitive scores were used to assess global, general, attention, and executive function domains. Nut consumption was categorized as Results: Nut consumption was positively associated with 2-y changes in general cognitive function (P-trend Conclusion: Frequent nut consumption was associated with a smaller decline in general cognitive performance over 2 y in older adults at risk of cognitive decline. Randomized clinical trials to verify our findings are warranted

Pro-vegetarian food patterns and cardiometabolic risk in the PREDIMED-Plus study: a cross-sectional baseline analysis

[Purpose]: We explored the cross-sectional association between the adherence to three different provegetarian (PVG) food patterns defined as general (gPVG), healthful (hPVG) and unhealthful (uPVG), and the cardiometabolic risk in adults with metabolic syndrome (MetS) of the PREDIMED-Plus randomized intervention study. [Methods]: We performed a cross-sectional analysis of baseline data from 6439 participants of the PREDIMED-Plus randomized intervention study. The gPVG food pattern was built by positively scoring plant foods (vegetables/fruits/legumes/grains/potatoes/nuts/olive oil) and negatively scoring, animal foods (meat and meat products/animal fats/eggs/fish and seafood/dairy products). The hPVG and uPVG were generated from the gPVG by adding four new food groups (tea and coffee/fruit juices/sugar-sweetened beverages/sweets and desserts), splitting grains and potatoes and scoring them differently. Multivariable-adjusted robust linear regression using MM-type estimator was used to assess the association between PVG food patterns and the standardized Metabolic Syndrome score (MetS z-score), a composed index that has been previously used to ascertain the cardiometabolic risk, adjusting for potential confounders. [Results]: A higher adherence to the gPVG and hPVG was associated with lower cardiometabolic risk in multivariable models. The regression coefficients for 5th vs. 1st quintile were − 0.16 (95% CI: − 0.33 to 0.01) for gPVG (p trend: 0.015), and − 0.23 (95% CI: − 0.41 to − 0.05) for hPVG (p trend: 0.016). In contrast, a higher adherence to the uPVG was associated with higher cardiometabolic risk, 0.21 (95% CI: 0.04 to 0.38) (p trend: 0.019). [Conclusion]: Higher adherence to gPVG and hPVG food patterns was generally associated with lower cardiovascular risk, whereas higher adherence to uPVG was associated to higher cardiovascular risk.This work was supported by the official Spanish Institutions for funding scientific biomedical research, CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN) and Instituto de Salud Carlos III (ISCIII), through the Fondo de Investigación para la Salud (FIS), which is co-funded by the European Regional Development Fund (six coordinated FIS projects leaded by JS-S and JVi, including the following projects: PI13/00673, PI13/00492, PI13/00272, PI13/01123, PI13/00462, PI13/00233, PI13/02184, PI13/00728, PI13/01090, PI13/01056, PI14/01722, PI14/00636, PI14/00618, PI14/00696, PI14/01206, PI14/01919, PI14/00853, PI14/01374, PI14/00972, PI14/00728, PI14/01471, PI16/00473, PI16/00662, PI16/01873, PI16/01094, PI16/00501, PI16/00533, PI16/00381, PI16/00366, PI16/01522, PI16/01120, PI17/00764, PI17/01183, PI17/00855, PI17/01347, PI17/00525, PI17/01827, PI17/00532, PI17/00215, PI17/01441, PI17/00508, PI17/01732, PI17/00926, PI19/00957, PI19/00386, PI19/00309, PI19/01032, PI19/00576, PI19/00017, PI19/01226, PI19/00781, PI19/01560, PI19/01332, PI20/01802, PI20/00138, PI20/01532, PI20/00456, PI20/00339, PI20/00557, PI20/00886, PI20/01158); the Especial Action Project entitled: Implementación y evaluación de una intervención intensiva sobre la actividad física Cohorte PREDIMED-Plus grant to JS-S; the European Research Council (Advanced Research Grant 2014–2019; agreement #340918) granted to MÁM-G.; the Recercaixa (number 2013ACUP00194) grant to JS-S; grants from the Consejería de Salud de la Junta de Andalucía (PI0458/2013, PS0358/2016, PI0137/2018); the PROMETEO/2017/017 grant from the Generalitat Valenciana; the SEMERGEN grant; None of the funding sources took part in the design, collection, analysis, interpretation of the data, or writing the report, or in the decision to submit the manuscript for publication

Obstetric outcomes of sars-cov-2 infection in asymptomatic pregnant women

Altres ajuts: Fondo Europeo de Desarrollo Regional (FEDER)Around two percent of asymptomatic women in labor test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Spain. Families and care providers face childbirth with uncertainty. We determined if SARS-CoV-2 infection at delivery among asymptomatic mothers had different obstetric outcomes compared to negative patients. This was a multicenter prospective study based on universal antenatal screening for SARS-CoV-2 infection. A total of 42 hospitals tested women admitted for delivery using polymerase chain reaction, from March to May 2020. We included positive mothers and a sample of negative mothers asymptomatic throughout the antenatal period, with 6-week postpartum follow-up. Association between SARS-CoV-2 and obstetric outcomes was evaluated by multivariate logistic regression analyses. In total, 174 asymptomatic SARS-CoV-2 positive pregnancies were compared with 430 asymptomatic negative pregnancies. No differences were observed between both groups in key maternal and neonatal outcomes at delivery and follow-up, with the exception of prelabor rupture of membranes at term (adjusted odds ratio 1.88, 95% confidence interval 1.13-3.11; p = 0.015). Asymptomatic SARS-CoV-2 positive mothers have higher odds of prelabor rupture of membranes at term, without an increase in perinatal complications, compared to negative mothers. Pregnant women testing positive for SARS-CoV-2 at admission for delivery should be reassured by their healthcare workers in the absence of symptoms

Estudios sobre violencia en la educación. Enfoques, textos y contextos

El concepto de la violencia ha estado sobre la palestra desde el principio de nuestras sociedades. No obstante, en la práctica sus facetas son múltiples y en diversos ámbitos, lo que ha dado lugar a especulaciones acerca de los medios y los fines. Esto mismo incita a reflexionar en lo axiológico, pues la violencia alberga en sí un elemento adicional de arbitrariedad y, por lo tanto, se relaciona con aspectos fundamentales del derecho o los derechos humanos. En los ámbitos educativos han aparecido nuevas formas de violencia personal, que se reflejan en el bullying y el mobbing. En el ámbito universitario, existe un malestar que no se palía con estímulos o clientelismos y que se refiere a un tipo de violencia particular soterrada por las políticas públicas y el intervencionismo del Estado, los cuales han provocado tensiones entre las comunidades académicas; éstas tienen que ver con la defensa de los principios de libertad y autonomía de cátedra e investigación. En algunos casos, dichas voces han formulado críticas a los programas impuestos, ya que éstos se establecen sin reflexionar en los costos sociales que provocan en el trabajo académico y científico. De esas formas de violencia se quiere dar cuenta en esta obra, la cual fue desarrollada por la Red de Cuerpos Académicos en Política, Educación y Universidad

Circulating carotenoids are associated with favorable lipid and fatty acid profiles in an older population at high cardiovascular risk

Carotenoid intake has been reported to be associated with improved cardiovascular health, but there is little information on actual plasma concentrations of these compounds as biomarkers of cardiometabolic risk. The objective was to investigate the association between circulating plasma carotenoids and different cardiometabolic risk factors and the plasma fatty acid profile. This is a cross-sectional evaluation of baseline data conducted in a subcohort (106 women and 124 men) of an ongoing multi-factorial lifestyle trial for primary cardiovascular prevention. Plasma concentrations of carotenoids were quantified by liquid chromatography coupled to mass spectrometry. The associations between carotenoid concentrations and cardiometabolic risk factors were assessed using regression models adapted for interval-censored variables. Carotenoid concentrations were cross-sectionally inversely associated with serum triglyceride concentrations [-2.79 mg/dl (95% CI: -4.25, -1.34) and -5.15 mg/dl (95% CI: -7.38, -2.93), p-values = 0.0002 and <0.00001 in women and men, respectively], lower levels of plasma saturated fatty acids [-0.09% (95% CI: -0.14, -0.03) and -0.15 % (95% CI: -0.23, -0.08), p-values = 0.001 and 0.0001 in women and men, respectively], and higher levels of plasma polyunsaturated fatty acids [(0.12 % (95% CI: -0.01, 0.25) and 0.39 % (95% CI: 0.19, 0.59), p-values = 0.065 and 0.0001 in women and men, respectively] in the whole population. Plasma carotenoid concentrations were also associated with higher plasma HDL-cholesterol in women [0.47 mg/dl (95% CI: 0.23, 0.72), p-value: 0.0002], and lower fasting plasma glucose in men [-1.35 mg/dl (95% CI: -2.12, -0.59), p-value: 0.001]. Keywords: Mediterranean diet; PREDIMED-plus study; cardiovascular health; liquid chromatography; mass spectrometry; plasma carotenoids