Osgood Bradbury

An article that appeared in the Lewiston Daily Sun on Maine author Osgood Bradbury

Extending Functional kriging to a multivariate context

Environmental data usually have a spatio-temporal structure; pollutant concentrations, for example, are recorded along time and space. Generalized Additive Models (GAMs) represent a suitable tool to model spatial and/or temporal trends of this kind of data, that can be treated as functional, although they are collected as discrete observations. Frequently, the attention is focused on the prediction of a single pollutant at an unmonitored site and, at this aim, we extend kriging for functional data to a multivariate context by exploiting the correlation with the other pollutants. In particular, we propose two procedures: the first one (FKED) combines the regression of a variable (pollutant), of primary interest on the other variables, with functional kriging of the regression residuals; the second one (FCK) is based on linear unbiased prediction of spatially correlated multivariate random processes. The performance of the two proposed procedures is assessed by cross validation; data recorded during a year (2011) from the monitoring network of the state of California (USA) are considered

Osgood Bradbury: A Biobibliographical Study

The writer became interested in the lack of information relating to the little-known Maine author of the nineteenth century, Osgood Bradbury. This biobibliographical study carries out a review of his life and work. Bradbury is almost completely unknown in Maine literary circles in spite of having written nearly sixty novels. Many aspects of his life are as nebulous as many of the characters in his own stories. Even his birthdate is suspect, although there is some evidence to indicate that he was born in 1795, in New Gloucester, Maine. The writer found no evidence of his whereabouts from his birthdate to 1823, until she discovered a letter in his own hand in the Chandler Family records. Other evidence indicates that Bradbury lived in and around New Gloucester during these years until 1844, when he is found listed in the Boston City Directory as a counsellor. In 1845, at the age of fifty, Bradbury married a much younger woman in Vermont, but no evidence was found to place him anywhere but in Boston. There is evidence, however, that he returned to Maine in 1862, this time to Portland where he became the associate editor and later editor of the Portland Advertiser. In 1874, Bradbury is found making a speech at the centennial celebration of New Gloucester. This speech revealed some interesting facets of his life and was helpful to the biographical phase of this study. The United States Census of 1880 listed him as living in New Gloucester and indicated that he was a lawyer. And, finally, in 1886, a meager light-line obituary in the Boston Evening Transcript carried the news of his death at age ninety-one in New Gloucester. Osgood Bradbury left no children, but he did leave a large family of novels. Although these novels have not been recognized by literary critics or historians, they do provide an insight into the character and personality of the man and his involvement in the social and political scene of his time. In his literary work very little has been known about him as many of his works were either unsigned or identified only as by a member of the Suffolk Bar, for example. In many of his novels the reader is aware of his personal crusade for temperance. He made his temperance novels vehicles for teaching. In other stories, he seemed obsessed with the brothels of the day and prostitution in general. Illegitimacy is also a recurring theme along with other social ills such as the plight of widows and orphans, the infidelity of husbands, and even murder. These also show the evidence of his Christian character and his interest in women\u27s rights. Each of the novels is studied and the annotations recount the plot and attempt to relate elements in each story to the experiences, character, and personality of Osgood Bradbury as a man and member of the society in which he found himself. Much information about Bradbury has been discovered but there still remains much about him that is unknown. Includes photoprints of covers from five of Osgood Bradbury\u27s novels: Mattalak, the Lone Indian of the Magalloway; Alice Marvin, or, The Fisherman\u27s Daughter; Francis Abbott, or, The Hermit of Niagara; Larooka, The Belle of the Belle of the Penobscots; Isabelle, or, The Emigrant\u27s Daughter

A quasi quarant’anni dalla strage di Ustica: la memoria della prospettiva giudiziaria

L’analisi, a distanza di quasi quarant’anni dalla strage di Ustica, di alcune parti della sentenza-ordinanza del giudice istruttore Priore e di alcune delle pronunce rese in sede civile consente almeno tre tipi di riflessioni. La prima interessa, nel momento di passaggio dal codice di rito del 1930 a quello attuale, le forme dell’attività dell’allora giudice inquirente, secondo quella che può essere definita una “investigazione partecipata” lunga vent’anni. La seconda concerne la storia della ricerca delle tracce per la ricostruzione del fatto, sin dall’inizio soppresse o alterate. La terza, infine, riguarda i diritti dei parenti delle vittime, “soddisfatti” solo da un punto di vista patrimoniale

GAMs and functional kriging for air quality data

Data having spatio-temporal structure are often observed in environmental sciences. They may be considered as discrete observations from curves along time and/or space and treated as functional. Generalized Additive Models (GAMs) represent a useful tool for modelling, for example, as pollutant concentrations describing their spatial and/or temporal trends.Usually, the prediction of a curve at an unmonitored site is necessary and, with this aim, we extend kriging for functional data to a multivariate context. Moreover, even if we are interested only in predicting a single pollutant, such as PM10, the estimation can be improved exploiting its correlation with the other pollutants. Cross validation is used to test the performance of the proposed procedure

Towards a Digital Ecosystem of Trust: Ethical, Legal and Societal Implications

The European vision of a digital ecosystem of trust rests on innovation, powerful technological solutions, a comprehensive regulatory framework and respect for the core values and principles of ethics. Innovation in the digital domain strongly relies on data, as has become obvious during the current pandemic. Successful data science, especially where health data are concerned, necessitates establishing a framework where data subjects can feel safe to share their data. In this paper, methods for facilitating data sharing, privacy-preserving technologies, decentralization, data altruism, as well as the interplay between the Data Governance Act and the GDPR, are presented and discussed by reference to use cases from the largest pan-European social science data research project, SoBigData++. In doing so, we argue that innovation can be turned into responsible innovation and Europe can make its ethics work in digital practice

Building new business model from multiple case study research in the Internet of Me

The digital revolution has greatly changed the approach to culture, work, leisure time, the way we interact and communicate with people: the digitization of information has taken root and has become essential in all areas of social life as a phenomenon that guides and monitors the transformation of society in all its various forms, bringing great changes in almost all areas and especially in the world of work and industry. Industry 4.0 refers to a fourth industrial revolution (following water/steam power, mass production and automation through IT and robotics) and introduces the concept of "cyber-physical systems" to differentiate this new evolutionary phase from the electronic automation that has gone before. The term Industry 4.0 refers to the next phase in the digitization of the manufacturing sector, driven by four disruptions: 1) the astonishing rise in data volumes, computational power, and connectivity, especially new low-power wide-area networks; 2) the emergence of analytics and business-intelligence capabilities; 3) new forms of human-machine interaction such as touch interfaces and augmented-reality systems; 4) improvements in transferring digital instructions to the physical world, such as advanced robotics and 3-D printing. One of the core elements of the fourth industrial revolution is the systematic application of IoT technologies (Internet of Things) and IoM (Internet of Me) to production processes on a global scale. The aim of the paper is primarily an analysis of what are the possible future benefits of IoT and IoM, trying to understand the effort and their opportunities for a consumer oriented business. Then to analyze the competitive advantage that companies are pursuing when they implement a business which is IoT / IoM oriented. The project research question relates to the possible extrapolation of a standardized behavioural pattern, in order to draw guidelines for companies who want to start a similar strategic management, through the direct experiences of an Italian start-up first mover group in the sectors involved in IoT and IoM revolution, defining risks, opportunities and threats. Theresearch presents two phases methodologically joinedbetween them: from a theoretical point of view it is defined the change from the Business Model towards the “ecosystem” of Business Model in the strategy IoT/IoM oriented,and from a empirical point of view the business development of some start-up companies using IoT and IoM technologies is studied, through the direct interview qualitative tool

paving the path for invasion the polyedric role of lasp1 in cancer

Although usually referred to as a structural actin-binding protein, LIM and SH3 domain-containing protein may actually be dynamically involved in the control of a wide spectrum of cellular processes, by virtue of its interaction with several molecular partners. Alongside being ubiquitously expressed in physiological conditions, LIM and SH3 domain-containing protein is overexpressed in a growing number of human cancers, in which it may actively contribute to their aggressiveness by promoting cell proliferation and migration. In view of the recent findings, implicating the protein in cancer progression, we discuss here the most relevant discoveries highlighting the role of this versatile protein in various human tumors. The correlation between LIM and SH3 domain-containing protein expression levels in cancer and the poor outcome and metastatic behavior of tumors denotes the clinical significance of this protein and hints its potential value as a new cancer prognostic or even diagnostic biomarker. This may be decisive not only to optimize existing pharmacological regimes but also to delineate novel, more efficacious therapeutic and/or preventive approaches