Onset of dissipation in ballistic atomic wires

Electronic transport at finite voltages in free-standing gold atomic chains of up to 7 atoms in length is studied at low temperatures using a scanning tunneling microscope (STM). The conductance vs voltage curves show that transport in these single-mode ballistic atomic wires is non-dissipative up to a finite voltage threshold of the order of several mV. The onset of dissipation and resistance within the wire corresponds to the excitation of the atomic vibrations by the electrons traversing the wire and is very sensitive to strain.Comment: Revtex4, 4 pages, 3 fig

Working the approach to nature of children in Early Childhood Education Degree. Crucial in today's society

Los niños y niñas de la sociedad actual se encuentran alejados de entornos naturales y están necesitados de contacto con la naturaleza, lo que puede ser el motivo de distintos síntomas como estrés o ansiedad. Existen investigaciones que muestran que el contacto con la naturaleza es beneficioso para el desarrollo de los infantes además de fomentar una actitud más pro-ambiental. En este trabajo se pretende concienciar al alumnado del Grado de Educación Infantil de dichos beneficios mediante la ejecución de una serie de actividades centradas en el uso de los parques urbanos como recurso para el acercamiento a la naturaleza de los niños y las niñas de la etapa de infantil. Es necesario que tanto universidad, escuela y familia fomenten el uso y disfrute de estos espacios.Children in today's society are far from natural environments and in need of contact with nature, which may be why various symptoms such as stress or anxiety. There is research showing that contact with nature is beneficial to the development of infants in addition to encouraging a more pro-environmental attitude. This paper aims to educate the students of the Degree in Early Childhood Education of those benefits by implementing a series of activities focused on the use of urban parks as a resource for the approach to the nature of children. It is necessary that university, school and family encourage the use and enjoyment of these spaces

Insights on biodiversity drivers to predict species richness in tropical forests at the local scale

Disentangling the relative importance of different biodiversity drivers (i.e., climate, edaphic, historical factors, or human impact) to predict plant species richness at the local scale is one of the most important challenges in ecology. Biodiversity modelling is a key tool for the integration of these drivers and the predictions generated are essential, for example, for climate change forecast and conservation planning. However, the reliability of biodiversity models at the local scale remains poorly understood, especially in tropical species-rich areas, where they are required. We inventoried all woody plants with stems ≥ 2.5 cm in 397 plots across the Andes-Amazon gradient. We generated and mapped 19 uncorrelated biodiversity drivers at 90 m resolution, grouped into four categories: microclimatic, microtopographic, anthropic, and edaphic. In order to evaluate the importance of the different categories, we grouped biodiversity drivers into four different clusters by categories. For each of the four clusters of biodiversity drivers, we modelled the observed species richness using two statistical techniques (random forest and Bayesian inference) and two modelling procedures (including or excluding a spatial component). All the biodiversity models produced were evaluated by cross-validation. Species richness was accurately predicted by random forest (Spearman correlation up to 0.85 and explained variance up to 67%). The results suggest that precipitation and temperature are important driving forces of species richness in the region. Nonetheless, a spatial component should be considered to properly predict biodiversity. This could reflect macroevolutionary underlying forces not considered here, such as colonization time, dispersal capacities, or speciation rates. However, the proposed biodiversity modelling approach can predict accurately species richness at the local scale and detailed resolution (90 m) in tropical areas, something that previous works had found extremely challenging. The innovative methodology presented here could be employed in other areas with conservation needsWe thank the Consejería de Educacion (Comunidad de Madrid, Spain), National Geographic Society (8047-06, 7754-04), National Science Foundation (DEB#0101775, DEB#0743457, DEB#1557094), Spanish Ministry of Economy and Competitiveness (CGL2016-75414-P), Centro de Estudios de América Latina (Universidad Autonoma de Madrid – Banco Santander), Consejería de Educacion, Cultura y Deportes (Junta de Comunidades de Castilla-La Mancha, SBPLY/21/180501/000241), Spanish Ministry of Economy and Competitiveness (PID2019-106341GB-I00) for funding our research. The full dataset can be requested from the Madidi Project (https://madidiproject.weebly.com/

The Role of Emotional Regulation and Affective Balance on Health Perception in Cardiovascular Disease Patients According to Sex Differences

One of the challenges of aging is the increase of people with chronic diseases, such as cardiovascular disease (CVD). Men and women experience the disease differently. Therefore, it has an impact on how CVD is treated and its outcomes. This research analyzed the relationship between psychosocial variables and health promotion among cardiovascular patients, paying special attention to sex differences. A longitudinal study with cardiovascular patients (747 in phase 1 (122 women) and 586 in phase 2 (83 women)) was carried out. Participants were evaluated based on their sociodemographic characteristics, affective balance, regulatory negative affect self-efficacy, stress and anxiety regulation strategies, and perceived global health. Results showed that men presented significantly higher scores in positive affect, affective balance, and self-efficacy to regulate negative emotions, while women presented significantly higher scores in negative affect and the use of passive strategies to cope with stressful situations. Regression analyses showed that all psychological variables studied in phase 1 were significant predictors of health perception in phase 2. According to the results, it is necessary to include strategies to improve cardiovascular health through education and emotional regulation, with a gender focus.Ministerio de Economía y Competitividad PSI2014–58609-RMinisterio de Ciencia, Innovación y Universidades PDI2019-107304RB-I0

A Brief mHealth-Based Psychological Intervention in Emotion Regulation to Promote Positive Subjective Well-Being in Cardiovascular Disease Patients: A Non-Randomized Controlled Trial.

The emotional impact that a cardiovascular disease may have on a person's life can affect the prognosis and comorbidity of the disease. Therefore, emotion regulation is most important for the management of the disease. The aim of this study was to analyze the effectiveness of a brief mHealth psychological intervention in emotion regulation to promote positive subjective well-being in cardiovascular disease patients. The study sample (N = 69, 63.7 ± 11.5 years) was allocated to either the experimental group (n = 34) or control group (n = 35). The intervention consisted of a psychoeducational session in emotion regulation and an mHealth-based intervention for 2 weeks. Positive subjective well-being as a primary outcome and self-efficacy to manage the disease as a secondary outcome were assessed at five time points evaluated over a period of 6 weeks. The experimental group showed higher improvement in positive subjective well-being and self-efficacy for managing the disease compared to the control group over time. The experimental group also improved after the intervention on all outcome measures. Brief mHealth interventions in emotion regulation might be effective for improving positive subjective well-being and self-efficacy to manage the disease in cardiovascular patients

Genome-Wide Analysis of Factors Affecting Transcription Elongation and DNA Repair: A New Role for PAF and Ccr4-Not in Transcription-Coupled Repair

RNA polymerases frequently deal with a number of obstacles during transcription elongation that need to be removed for transcription resumption. One important type of hindrance consists of DNA lesions, which are removed by transcription-coupled repair (TC-NER), a specific sub-pathway of nucleotide excision repair. To improve our knowledge of transcription elongation and its coupling to TC-NER, we used the yeast library of non-essential knock-out mutations to screen for genes conferring resistance to the transcription-elongation inhibitor mycophenolic acid and the DNA-damaging agent 4-nitroquinoline-N-oxide. Our data provide evidence that subunits of the SAGA and Ccr4-Not complexes, Mediator, Bre1, Bur2, and Fun12 affect transcription elongation to different extents. Given the dependency of TC-NER on RNA Polymerase II transcription and the fact that the few proteins known to be involved in TC-NER are related to transcription, we performed an in-depth TC-NER analysis of a selection of mutants. We found that mutants of the PAF and Ccr4-Not complexes are impaired in TC-NER. This study provides evidence that PAF and Ccr4-Not are required for efficient TC-NER in yeast, unraveling a novel function for these transcription complexes and opening new perspectives for the understanding of TC-NER and its functional interconnection with transcription elongation

Impact of interstitial lung disease on the survival of systemic sclerosis with pulmonary arterial hypertension

To assess severity markers and outcomes of patients with systemic sclerosis (SSc) with or without pulmonary arterial hypertension (PAH-SSc/non-PAH-SSc), and the impact of interstitial lung disease (ILD) on PAH-SSc. Non-PAH-SSc patients from the Spanish SSc registry and PAH-SSc patients from the Spanish PAH registry were included. A total of 364 PAH-SSc and 1589 non-PAH-SSc patients were included. PAH-SSc patients had worse NYHA-functional class (NYHA-FC), worse forced vital capacity (FVC) (81.2 +/- 20.6% vs 93.6 +/- 20.6%, P < 0.001), worse tricuspid annular plane systolic excursion (TAPSE) (17.4 +/- 5.2 mm vs 19.9 +/- 6.7 mm, P < 0.001), higher incidence of pericardial effusion (30% vs 5.2%, P < 0.001) and similar prevalence of ILD (41.8% vs. 44.9%). In individuals with PAH-SSc, ILD was associated with worse hemodynamics and pulmonary function tests (PFT). Up-front combination therapy was used in 59.8% and 61.7% of patients with and without ILD, respectively. Five-year transplant-free survival rate was 41.1% in PAH-SSc patients and 93.9% in non-PAH-SSc patients (P < 0.001). Global survival of PAH-SSc patients was not affected by ILD regardless its severity. The multivariate survival analysis in PAH-SSc patients confirmed age at diagnosis, worse NYHA-FC, increased PVR, reduced DLCO, and lower management with up-front combination therapy as major risk factors. In conclusion, in PAH-SSc cohort risk of death was greatly increased by clinical, PFT, and hemodynamic factors, whereas it was decreased by up-front combination therapy. Concomitant ILD worsened hemodynamics and PFT in PAH-SSc but not survival regardless of FVC impairment

Impact of interstitial lung disease on the survival of systemic sclerosis with pulmonary arterial hypertension

To assess severity markers and outcomes of patients with systemic sclerosis (SSc) with or without pulmonary arterial hypertension (PAH-SSc/non-PAH-SSc), and the impact of interstitial lung disease (ILD) on PAH-SSc. Non-PAH-SSc patients from the Spanish SSc registry and PAH-SSc patients from the Spanish PAH registry were included. A total of 364 PAH-SSc and 1589 non-PAH-SSc patients were included. PAH-SSc patients had worse NYHA-functional class (NYHA-FC), worse forced vital capacity (FVC) (81.2 ± 20.6% vs 93.6 ± 20.6%, P &lt; 0.001), worse tricuspid annular plane systolic excursion (TAPSE) (17.4 ± 5.2 mm vs 19.9 ± 6.7 mm, P &lt; 0.001), higher incidence of pericardial effusion (30% vs 5.2%, P &lt; 0.001) and similar prevalence of ILD (41.8% vs. 44.9%). In individuals with PAH-SSc, ILD was associated with worse hemodynamics and pulmonary function tests (PFT). Up-front combination therapy was used in 59.8% and 61.7% of patients with and without ILD, respectively. Five-year transplant-free survival rate was 41.1% in PAH-SSc patients and 93.9% in non-PAH-SSc patients (P &lt; 0.001). Global survival of PAH-SSc patients was not affected by ILD regardless its severity. The multivariate survival analysis in PAH-SSc patients confirmed age at diagnosis, worse NYHA-FC, increased PVR, reduced DLCO, and lower management with up-front combination therapy as major risk factors. In conclusion, in PAH-SSc cohort risk of death was greatly increased by clinical, PFT, and hemodynamic factors, whereas it was decreased by up-front combination therapy. Concomitant ILD worsened hemodynamics and PFT in PAH-SSc but not survival regardless of FVC impairment

Sistema de evaluación institucional en enseñanza obligatoria en Iberoamérica

La presente aportación se focaliza, en este contexto, en la evaluación institucional externa (vinculada o no a la autoevaluación interna) y, por tanto, considera prioritariamente la manera como se evalúan los centros educativos como totalidad y no tanto alguno de sus aspectos (evaluación de la dirección, de los profesores, de los programas, etc.), que también pueden estar considerados. El énfasis también está en conocer la organización y desarrollo del sistema de evaluación. Recoge la visión de 43 especialistas de trece países iberoamericanos sobre las formas de entender y promover la evaluación institucional en sus centros educativos. Sus aportaciones, que deben contextualizarse en las particularidades educativas de sus países (ya presentadas en anteriores informes de la RedAGE), presentan los aspectos generales y normativos de la evaluación, las formas cómo se organiza, los efectos institucionales que tienen y algunas reflexiones, retos y propuestas para la mejora. Su orientación es claramente práctica y se vincula al encuentro anual que la RedAGE realizado los días 16 y 17 de mayo de 2016 en la ciudad de Leiria (Portugal). Allí, los representantes de las organizaciones miembro seleccionaron la temática por su interés actual (con clara vinculación a la mejora de los sistemas educativos y la acreditación institucional), consensuaron la estructura de las aportaciones y realizaron un intercambio de posibles ideas sobre la temática. Se cubre así y como en ocasiones anteriores el propósito fundamental de la RedAGE, como es el de fomentar el intercambio de experiencias, la promoción del conocimiento sobre administración y gestión educativa y la reflexión sobre la práctica de la gestión. La finalidad última sigue siendo la de mejorar el funcionamiento de los centros educativos (y, a través de ellos, de los sistemas educativos), procurando sean de calidad y un instrumento para el cambio profesional y social