National Autism Indicators Report: Vocational Rehabilitation 2016

Employment is about more than simply earning a paycheck - it influences quality of life, independence, and wellness. Historically, employment outcomes for adults with autism are poor. The U.S. Vocational Rehabilitation system (VR) is designed to provide support to states for implementation of services to assist people with disabilities to prepare for, find, and keep employment. VR data allow us to examine some outcomes for those with autism compared to their peers.To make a difference, research must reach those who need it. The National Autism Indicators Report series presents our research findings in a clearly communicated, open-access, online format to speed the delivery of information to decision-makers while maintaining very high standards of scientific credibility

National Autism Indicators Report: Transition into Young Adulthood

There is very little research published concerning how people with autism do in the adult portion of their lifespans. We analyzed data from "The National Longitudinal Transition Study-2" and "The Survey of Pathways to Diagnosis and Services" to examine the service needs and life outcomes of adolescents and young adults on the autism spectrum. This report describes the prevalence of a wide variety of indicators related to transition planning, services access, unmet needs, employment, postsecondary education, living arrangements, social participation, and safety and risk

Using the National Early Warning Score (NEWS) outside acute hospital settings: A qualitative study of staff experiences in the West of England

© 2018 Author(s) (or their employer(s)). Objectives Early warning scores were developed to improve recognition of clinical deterioration in acute hospital settings. In England, the National Early Warning Score (NEWS) is increasingly being recommended at a national level for use outside such settings. In 2015, the West of England Academic Health Science Network supported the roll-out of NEWS across a range of non-acute-hospital healthcare sectors. Research on the use of NEWS outside acute hospitals is limited. The objective of this study was to explore staff experiences of using NEWS in these new settings. Design Thematic analysis of qualitative semi-structured interviews with purposefully sampled healthcare staff. Setting West of England healthcare settings where NEWS was being used outside acute hospitals - primary care, ambulance, referral management, community and mental health services. Participants Twenty-five healthcare staff interviewed from primary care (9), ambulance (3), referral management/acute interface (5), community (4) and mental health services (3), and service commissioning (1). Results Participants reported that NEWS could support clinical decision-making around escalation of care, and provide a clear means of communicating clinical acuity between clinicians and across different healthcare organisations. Challenges with implementing NEWS varied - in primary care, clinicians had to select patients for NEWS and adopt different methods of clinical assessment, whereas for paramedics it fitted well with usual clinical practice and was used for all patients. In community services and mental health, modifications were 'needed' to make the tool relevant to some patient populations. Conclusions This study demonstrated that while NEWS can work for staff outside acute hospital settings, the potential for routine clinical practice to accommodate NEWS in such settings varied. A tailored approach to implementation in different settings, incorporating guidance supported by further research on the use of NEWS with specific patient groups in community settings, may be beneficial, and enhance staff confidence in the tool

From Individual to Collective Pinning: Effect of Long-range Elastic Interactions

We study the effect of long-range elastic interactions in the dynamical behavior of an elastic chain driven quasi-statically in a quenched random pinning potential and in the strong pinning limit. This is a generic situation occuring in solid friction, crack propagation, wetting front motion, ... Tuning the exponent of the algebraic decay of the elastic interaction with the distance is shown to give rise to three regimes: a Mean-Field (MF) regime, a Laplacian (L) regime and an intermediate regime where the critical exponents interpolate continuously between the MF and L limit cases. The effect of the driving mode on the avalanche statistics is also analyzed.Comment: 28 pages in RevTex, 17 figure

Services for Adults with an Autism Spectrum Disorder

Objective: The need for useful evidence about services is increasing as larger numbers of children identified with an autism spectrum disorder age toward adulthood. The objective of this review was to characterize the topical and methodological aspects of research on services for supporting success in work, education, and social participation among adults with an autism spectrum disorder and to propose recommendations for moving this area of research forward. Method: Review of literature published in English from 2000 to 2010.Results: We found that the evidence base about services for adults with an ASD is underdeveloped and can be considered a field of inquiry that is relatively unformed. Extant research does not reflect the demographic or impairment heterogeneity of the population, the range of services that adults with autism require in order to function with purposeful lives in the community, and the need for coordination across service systems and sectors. Conclusions: Future studies must examine issues related to cost and efficiency given the broader sociopolitical and economic context of service provision. Furthermore, future research needs to consider how demographic and impairment heterogeneity have implications for building an evidence base that will have greater external validity

Postsecondary Employment Experiences among Young Adults with an Autism Spectrum Disorder

Objective: We examined postsecondary employment experiences of young adults with an autism spectrum disorder (ASD) and compared these outcomes with those of young adults with different disabilities. Method: Data were from Wave 5 of the National Longitudinal Transition Study 2 (NLTS2), a nationally representative survey of young adults who had received special education services during high school. We examined the prevalence of ever having had—and currently having—a paid job at 21–25 years of age. We analyzed rates of full employment, wages earned, number of jobs held since high school, and job types. Results: About half (53.4%) of young adults with an ASD had ever worked for pay outside the home since leaving high school, the lowest rate among disability groups. Young adults with an ASD earned an average of $8.10 per hour, significantly lower than average wages for young adults in the comparison groups, and held jobs that clustered within fewer occupational types. Odds of ever having had a paid job were higher for those who were older, from higher-income households, and with better conversational abilities or functional skills. Conclusions: Findings of worse employment outcomes for young adults with an ASD suggest this population is experiencing particular difficulty in successfully transitioning into employment. Research is needed to determine strategies for improving outcomes as these young adults transition into adulthood

Species-energy relationships of indigenous and invasive species may arise in different ways - a demonstration using springtails

Although the relationship between species richness and available energy is well established for a range of spatial scales, exploration of the plausible underlying explanations for this relationship is less common. Speciation, extinction, dispersal and environmental flters all play a role. Here we make use of replicated elevational transects and the insights ofered by comparing indigenous and invasive species to test four proximal mechanisms that have been ofered to explain relationships between energy availability, abundance and species richness: the sampling mechanism (a null expectation), and the more individuals, dynamic equilibrium and range limitation mechanisms. We also briefy consider the time for speciation mechanism. We do so for springtails on sub-Antarctic Marion Island. Relationships between energy availability and species richness are stronger for invasive than indigenous species, with geometric constraints and area variation playing minor roles. We reject the sampling and more individuals mechanisms, but show that dynamic equilibrium and range limitation are plausible mechanisms underlying these gradients, especially for invasive species. Time for speciation cannot be ruled out as contributing to richness variation in the indigenous species. Diferences between the indigenous and invasive species highlight the ways in which deconstruction of richness gradients may usefully inform investigations of the mechanisms underlying them. They also point to the importance of population size-related mechanisms in accounting for such variation. In the context of the subAntarctic our fndings suggest that warming climates may favour invasive over indigenous species in the context of changes to elevational distributions, a situation found for vascular plants, and predicted for springtails on the basis of smaller-scale manipulative feld experiments.South African National Research Foundationhttp://www.nature.com/sreppm2020Plant Production and Soil Scienc

The clinical Pseudomonas fluorescens MFN1032 strain exerts a cytotoxic effect on epithelial intestinal cells and induces Interleukin-8 via the AP-1 signaling pathway

International audienc

Fuzzy species limits in Mediterranean gorgonians (Cnidaria, Octocorallia): inferences on speciation processes

The study of the interplay between speciation and hybridization is of primary importance in evolutionary biology. Octocorals are ecologically important species whose shallow phylogenetic relationships often remain to be studied. In the Mediterranean Sea, three congeneric octocorals can be observed in sympatry: Eunicella verrucosa, Eunicella cavolini and Eunicella singularis. They display morphological differences and E.singularis hosts photosynthetic Symbiodinium, contrary to the two other species. Two nuclear sequence markers were used to study speciation and gene flow between these species, through network analysis and Approximate Bayesian Computation (ABC). Shared sequences indicated the possibility of hybridization or incomplete lineage sorting. According to ABC, a scenario of gene flow through secondary contact was the best model to explain these results. At the intraspecific level, neither geographical nor ecological isolation corresponded to distinct genetic lineages in E.cavolini. These results are discussed in the light of the potential role of ecology and genetic incompatibilities in the persistence of species limits.French National Research Agency (ANR) program Adacni (ANR) [ANR-12-ADAP-0016]CNRSHubert Curien 'Tassili' program [12MDU853]CCMAR Strategic Plan from Fundacao para a Ciencia e a Tecnologia-FCT [PEst-C/MAR/LA0015/2011,FEDERinfo:eu-repo/semantics/publishedVersio