50 research outputs found
Changing trends in cardiovascular risk factors among adults in southern Nigeria
- Publication venue
- Medip Academy
- Publication date
- 28/02/2024
- Field of study
Background: Globally, cardiovascular diseases (CVDs) cause 17.9 million deaths yearly. In nations like Nigeria, diabetes, hypertension, and obesity, coupled with modifiable behaviors such as physical inactivity, unhealthy diet, smoking, and alcohol use, are rising. This study focused on assessing the evolving prevalence and distribution of CVD risk factors among adults in southern Nigeria.
Methods: This cross-sectional study, conducted in Port Harcourt, Rivers state, was part of world heart day celebrations over three years (September 2019-September 2023). 309 adults participated, undergoing screening for blood pressure, fasting blood glucose, lipid profile, and body mass index calculated from weight and height measurements.
Results: Over three years, 309 subjects (mean age 46.63±12.03) were studied, with 53.40% females and 46.28% males. Most cardiovascular risk factors occurred in the 41-50 age group. Hypertension rose from 65.63% (2019) to 75.29% (2023), dipping to 64.79% (2022). Obesity decreased from 29.69% (2019) to 24.71% (2023), rising to 30.99% (2022). Diabetes increased from 23.44% (2019) to 27.59% (2023), decreasing to 19.71% (2022). Total cholesterol rose from 1.56% (2019) to 2.9% (2023). High LDL increased from 3.12% (2019) to 12.7% (2023). Low HDL and high TRIG decreased from 2019 to 2023.
Conclusions: From 2019 to 2023, cardiovascular risk factors like hypertension, obesity, diabetes, and dyslipidemia increased, with a slight fluctuation in 2022. Heightened awareness and preventive measures against adult CVD risk factors are imperative. National education on risk factors is vital for individuals to monitor their blood pressure, weight, cholesterol, and blood sugar levels
Merrill Lynch Finance Committee Meeting Minutes
- Author
- Publication venue
- EliScholar â A Digital Platform for Scholarly Publishing at Yale
- Publication date
- 22/07/2007
- Field of study
Recommended from our members
Safeguarding pollinators and their values to human well-being
- Author
- A Holzschuh
- A Pauw
- A SĂĄez
- A Tehel
- A Traveset
- A Van Geert
- AB Jull
- Adam J. Vanbergen
- AJ Vanbergen
- AM Jönsson
- AM Klein
- AV Lopes
- BA Woodcock
- BR Blaauw
- C Carvell
- C Hanna
- C Kremen
- C Padoch
- C Polce
- CE Aslan
- CL Morales
- CM Kennedy
- D Gabriel
- D Senapathi
- D Zizumbo-Villarreal
- DA Andow
- DA Bohan
- DA Stanley
- DC Cook
- DM Bauer
- E Arias-CĂłyotl
- E Collison
- E GĂłmez-Baggethun
- EA Frimpong
- G Ekström
- G Ekström
- GKS Andersson
- H Waddington
- HCJ Godfray
- HCJ Godfray
- Hien T. Ngo
- I Bartomeus
- I Burton
- I Dohzono
- I Koh
- I-C Chen
- J Ollerton
- J Scheper
- J Scheper
- J Settele
- Jacobus C. Biesmeijer
- JC Biesmeijer
- JD van der Ploeg
- JJ Lever
- JJG Quezada-EuĂĄn
- JL Hernandez
- Josef Settele
- JP van der Sluijs
- JT Kerr
- L Wilfert
- LA Burkle
- LA Garibaldi
- LA Garibaldi
- LA Garibaldi
- LA Morandin
- LC Ponisio
- LG Carvalheiro
- Lucas A. Garibaldi
- LW Pisa
- Lynn V. Dicks
- M Barzman
- M Baude
- M Marvier
- M Rundlöf
- MA Aizen
- MA Aizen
- MA Aizen
- MA Altieri
- MA FĂŒrst
- Marcelo A. Aizen
- MC Gavin
- MG Park
- MK Schneider
- ML Forister
- MR Smith
- MS Warren
- N Gallai
- N Hanley
- O Schweiger
- P Barfoot
- P Cross
- P Neumann
- PR Steward
- R Bommarco
- R Chaplin-Kramer
- RF Pywell
- RFA Moritz
- RJ Gill
- RJ Gill
- Rosemary Hill
- S Lautenbach
- SA Cameron
- SA Rehel
- SG Potts
- SG Potts
- Simon G. Potts
- SJ Hegland
- SL Tuck
- TC Giannini
- TD Breeze
- Thomas D. Breeze
- U Kormann
- V Mommaerts
- Vera Imperatriz-Fonseca
- W Hunter
- X Junge
- Y Lu
- Ă Berg
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Wild and managed pollinators provide a wide range of benefits to society in terms of contributions to food security, farmer
and beekeeper livelihoods, social and cultural values, as well as the maintenance of wider biodiversity and ecosystem
stability. Pollinators face numerous threats, including changes in land-use and management intensity, climate change,
pesticides and genetically modified crops, pollinator management and pathogens, and invasive alien species. There are
well-documented declines in some wild and managed pollinators in several regions of the world. However, many effective
policy and management responses can be implemented to safeguard pollinators and sustain pollination services
Genome sequence of the tsetse fly (Glossina morsitans):Vector of African trypanosomiasis
- Author
- Abila Patrick P
- Acosta-Serrano Alvaro
- Aksoy Serap
- Aksoy Serap
- Aksoy Serap
- Aksoy Serap
- Arensburger Peter
- Aslett Martin
- Attardo Geoffrey M
- Attardo Geoffrey M
- Attardo Geoffrey M
- Attardo Geoffrey M
- Attardo Geoffrey M
- Auma Joanna E
- Balyeidhusa Apollo SP
- Bateta Rosemary
- Baumann Aaron A
- Benkahla Alia
- Benoit Joshua B
- Benoit Joshua B
- Benoit Joshua B
- Benoit Joshua B
- Benoit Joshua B
- Benoit Joshua B
- Berriman Matthew
- Berriman Matthew
- Berriman Matthew
- Bourtzis Kostas
- Bourtzis Kostas
- Brelsfoard Corey L
- Caers Jelle
- Caljon Guy
- Christoffels Alan
- Christoffels Alan
- Cotton James A
- Darby Alistair C
- Dashti Zahra Jalali Sefid
- Denlinger David L
- Falchetto Marco
- Field Linda M
- Friedrich Markus
- Fu Shuhua
- Gaede Gerd
- Gaunt Michael W
- Geiser Dawn L
- Githinji George
- Gomulski Ludvik M
- Gregory Richard
- Haines Lee R
- Hall Neil
- Hall Neil
- Hansen Imma A
- Hansen Immo A
- Harkins Gordon
- Hattori Masahira
- Hattori Masahira
- Hertz-Fowler Christiane
- Hide Winston
- Hide Winston
- Hu Wanqi
- Hughes Daniel ST
- Imanishi Tadashi
- Inoue Noboru
- Jonas Mario
- Jonas Mario
- Jones Jeffery W
- Kawahara Yoshihiro
- Kibet Caleb K
- Kinyua Johnson K
- Koekemoer Jacobus JO
- Koekemoer Jacobus JO
- Koffi Mathurin
- Kruger Adele
- Larkin Denis M
- Lawson Daniel
- Lehane Michael J
- Lehane Michael J
- Lehane Michael J
- Lehane Michael J
- Lehane Stella
- Lehvaeslaiho Heikki
- Luiz Thiago
- Macdonald Sandy J
- Macharia Rosaline W
- Makgamathe Mmule
- Malacrida Anna R
- Malele Imna
- Manangwa Oliver
- Manga Lucien
- Marco Heather G
- Marucha Kevin K
- Masiga Daniel K
- Masiga Daniel K
- Masiga Daniel K
- Megy Karyn
- Megy Karyn
- Meuti Megan E
- Michalkova Veronika
- Mireji Paul O
- Mireji Paul O
- Mireji Paul O
- Mireji Paul O
- Mpondo Feziwe
- Mramba Furaha
- Msangi Atway
- Mulder Nicola
- Murilla Grace
- Mwangi Sarah
- Nyanjom Steven RG
- Nyanjom Steven RG
- Obiero George FO
- Obiero George FO
- Okedi Loyce
- Okoro Chinyere K
- Omedo Irene A
- Ommeh Sheila
- Ooi Cher-Pheng
- Ooi Cher-Pheng
- Osamor Victor C
- Ouma Johnson
- Panji Sumir
- Peyton Justin T
- Pham Daphne QD
- Price David P
- Quail Michael A
- Ramphul Urvashi N
- Ravel Sophie
- Rawlings Neil D
- Ribeiro Jose MC
- Riehle Michael A
- Rio Rita VM
- Rio Rita VM
- Robertson Hugh M
- Rose Clair
- Sakate Ryuichi
- Sanders Mandy J
- Schoofs Liliane
- Scolari Francesca
- Scott Maxwell J
- Sharma Vineet
- Sharma Vineet
- Sim Cheolho
- Siwo Geoffrey
- Snyder Anna K
- Solano Philippe
- Srivastava Tulika P
- Stanley Eleanor J
- Stephens Dawn
- Suzuki Yutaka
- Swain Martin T
- Sze Sing-Hoi
- Tarone Aaron M
- Taylor Todd D
- Taylor Todd D
- Telleria Erich L
- Thomas Gavin H
- Toure Yeya
- Toyoda Atsushi
- Tsiamis George
- Tu Zhijian
- Van Den Abbeele Jan
- Walshe Deirdre P
- Walshe Deirdre P
- Wamalwa Mark
- Wamalwa Mark
- Wamwiri Florence
- Wang Jingwen
- Warren Wesley
- Watanabe Junichi
- Watanabe Junichi
- Watanabe Junichi
- Weiss Brian
- Willis Judith
- Wilson Richard K
- Wincker Patrick
- Winzerling Joy J
- Zhang Qirui
- Zhou Jing-Jiang
- Publication venue
- Publication date
- 01/01/2014
- Field of study
Tsetse flies are the sole vectors of human African trypanosomiasis throughout sub-Saharan Africa.
Both sexes of adult tsetse feed exclusively on blood and contribute to disease transmission. Notable
differences between tsetse and other disease vectors include obligate microbial symbioses, viviparous
reproduction, and lactation. Here, we describe the sequence and annotation of the 366-megabase
Glossina morsitans morsitans genome. Analysis of the genome and the 12,308 predicted
protein-encoding genes led to multiple discoveries, including chromosomal integrations of bacterial
(Wolbachia) genome sequences, a family of lactation-specific proteins, reduced complement of
host pathogen recognition proteins, and reduced olfaction/chemosensory associated genes. These
genome data provide a foundation for research into trypanosomiasis prevention and yield important
insights with broad implications for multiple aspects of tsetse biology.IS
2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales.
- Author
- Adkins Scott
- Agwanda Bernard R
- Agwanda Bernard R.
- Al Kubrusli Rim
- Alkhovsky Sergey V
- Alkhovsky Sergey V.
- Amarasinghe Gaya K
- Amarasinghe Gaya K.
- AvĆĄiÄ-Ćœupanc Tatjana
- AyllĂłn MarĂa A
- AyllĂłn MarĂa A.
- Bahl Justin
- Balkema-Buschmann Anne
- Ballinger Matthew J
- Ballinger Matthew J.
- Basler Christopher F
- Basler Christopher F.
- Bavari Sina
- Beer Martin
- Bejerman Nicolas
- Bennett Andrew J
- Bennett Andrew J.
- Bente Dennis A
- Bente Dennis A.
- Bergeron Ăric
- Bird Brian H
- Bird Brian H.
- Blair Carol D
- Blair Carol D.
- Blasdell Kim R
- Blasdell Kim R.
- Blystad Dag-Ragnar
- Bojko Jamie
- Borth Wayne B
- Borth Wayne B.
- Bradfute Steven
- Breyta Rachel
- Briese Thomas
- Brown Judith K
- Brown Judith K.
- Brown Paul A
- Brown Paul A.
- Buchholz Ursula J
- Buchholz Ursula J.
- Buchmeier Michael J
- Buchmeier Michael J.
- Bukreyev Alexander
- Burt Felicity
- BĂŒttner Carmen
- Calisher Charles H
- Calisher Charles H.
- Cao Mengji
- Casas Inmaculada
- Chandran Kartik
- Charrel RĂ©mi N
- Charrel RĂ©mi N.
- Cheng Qi
- Chiaki Yuya
- Chiapello Marco
- Choi Il-Ryong
- Ciuffo Marina
- Clegg J Christopher S
- Clegg J. Christopher S.
- Crozier Ian
- Dal BĂł Elena
- de la Torre Juan Carlos
- de Lamballerie Xavier
- de Souza William Marciel
- de Swart Rik L
- de Swart Rik L.
- Debat Humberto
- Dheilly Nolwenn M
- Dheilly Nolwenn M.
- Di Cicco Emiliano
- Di Paola Nicholas
- Di Serio Francesco
- Dietzgen Ralf G
- Dietzgen Ralf G.
- Digiaro Michele
- Dolnik Olga
- Drebot Michael A
- Drebot Michael A.
- Drexler J Felix
- Drexler J. Felix
- Dundon William G
- Dundon William G.
- Duprex W Paul
- Duprex W. Paul
- Dye John M
- Dye John M.
- DĂŒrrwald Ralf
- Easton Andrew J
- Easton Andrew J.
- Ebihara Hideki
- Elbeaino Toufic
- ErgĂŒnay Koray
- Ferguson Hugh W
- Ferguson Hugh W.
- Fooks Anthony R
- Fooks Anthony R.
- Forgia Marco
- Formenty Pierre B H
- Formenty Pierre B. H.
- Freitas-AstĂșa Juliana
- FrĂĄnovĂĄ Jana
- Fu Jingjing
- FĂŒrl Stephanie
- Gago-Zachert Selma
- GarcĂa MarĂa Laura
- GarcĂa-Sastre Adolfo
- Garrison Aura R
- Garrison Aura R.
- Gaskin Thomas
- Goldberg Tony L
- Goldberg Tony L.
- Gonzalez Jean-Paul J
- Gonzalez Jean-Paul J.
- Griffiths Anthony
- Groschup Martin H
- Groschup Martin H.
- GĂŒnther Stephan
- GÄo George FĂș
- Hall Roy A
- Hall Roy A.
- Hammond John
- Han Tong
- Hepojoki Jussi
- Hewson Roger
- Hong Jiang
- Hong Ni
- Hongo Seiji
- Horie Masayuki
- Hu John S
- Hu John S.
- Hu Tao
- Hughes Holly R
- Hughes Holly R.
- Hyndman Timothy H
- Hyndman Timothy H.
- HĂŒttner Florian
- Ilyas M
- Ilyas M.
- Jalkanen Risto
- JiÄng DĂ ohĂłng
- Jonson Gilda B
- Jonson Gilda B.
- Junglen Sandra
- Kadono Fujio
- Kaukinen Karia H
- Kaukinen Karia H.
- Kawate Michael
- Klempa Boris
- Klingström Jonas
- Kobinger Gary
- Koloniuk Igor
- KondĆ Hideki
- Koonin Eugene V
- Koonin Eugene V.
- Krupovic Mart
- Kubota Kenji
- Kuhn Jens H
- Kuhn Jens H.
- Kurath Gael
- Laenen Lies
- Lambert Amy J
- Lambert Amy J.
- Langevin Stanley L
- Langevin Stanley L.
- Lee Benhur
- Lefkowitz Elliot J
- Lefkowitz Elliot J.
- Leroy Eric M
- Leroy Eric M.
- Li Longhui
- Li Shaorong
- Liu Huazhen
- Lukashevich Igor S
- Lukashevich Igor S.
- Luna Gabriel Robles
- LÇ JiĂ nrĂłng
- Maes Piet
- Marklewitz Marco
- Marshall Sergio H
- Marshall Sergio H.
- Marzano Shin-Yi L
- Marzano Shin-Yi L.
- Massart Sebastien
- McCauley John W
- McCauley John W.
- Melzer Michael
- Mielke-Ehret Nicole
- Miller Kristina M
- Miller Kristina M.
- Ming Tobi J
- Ming Tobi J.
- Mirazimi Ali
- Mordecai Gideon J
- Mordecai Gideon J.
- MĂŒhlbach Hans-Peter
- MĂŒhlberger Elke
- Naidu Rayapati
- Natsuaki Tomohide
- Navarro José A
- Navarro José A.
- Netesov Sergey V
- Netesov Sergey V.
- Neumann Gabriele
- Nowotny Norbert
- Nunes MĂĄrcio R T
- Nunes MĂĄrcio R. T.
- Olmedo-Velarde Alejandro
- Palacios Gustavo
- PallĂĄs Vicente
- Papa Anna
- Paraskevopoulou Sofia
- Park Adam C
- Park Adam C.
- Parrish Colin R
- Parrish Colin R.
- Patterson David A
- Patterson David A.
- Pauvolid-CorrĂȘa Alex
- PawÄska Janusz T
- PawÄska Janusz T.
- Payne Susan
- Peracchio Carlotta
- Postler Thomas S
- Postler Thomas S.
- PĂĄlyi Bernadett
- PĂ©rez Daniel R
- PĂ©rez Daniel R.
- Qi Liying
- Radoshitzky Sheli R
- Radoshitzky Sheli R.
- Resende Renato O
- Resende Renato O.
- Reyes Carina A
- Reyes Carina A.
- Rima Bertus K
- Rima Bertus K.
- Romanowski VĂctor
- Rota Paul
- Rubbenstroth Dennis
- Rubino Luisa
- Runstadler Jonathan A
- Runstadler Jonathan A.
- Sabanadzovic Sead
- Sall Amadou Alpha
- Salvato Maria S
- Salvato Maria S.
- Sang Rosemary
- Sasaya Takahide
- Schulze Angela D
- Schulze Angela D.
- Schwemmle Martin
- Shi Mang
- Shimomoto Yoshifumi
- Shirako Yukio
- ShĂ XiÇohĂłng
- ShĂ ZhĂšnglĂŹ
- Siddell Stuart G
- Siddell Stuart G.
- Simmonds Peter
- Sironi Manuela
- Smagghe Guy
- Smither Sophie
- Song Jin-Won
- Spann Kirsten
- Spengler Jessica R
- Spengler Jessica R.
- Stenglein Mark D
- Stenglein Mark D.
- Stone David M
- Stone David M.
- Sugano Jari
- Suttle Curtis A
- Suttle Curtis A.
- Tabata Amy
- Takada Ayato
- Takeuchi Shigeharu
- Tchouassi David P
- Tchouassi David P.
- Teffer Amy
- Tesh Robert B
- Tesh Robert B.
- Thornburg Natalie J
- Thornburg Natalie J.
- Tomitaka Yasuhiro
- Tomonaga KeizĆ
- Tordo Noël
- Torto Baldwyn
- Towner Jonathan S
- Towner Jonathan S.
- Tsuda Shinya
- Tu Changchun
- Turina Massimo
- Tzanetakis Ioannis E
- Tzanetakis Ioannis E.
- Uchida Janice
- Usugi Tomio
- Vaira Anna Maria
- Vallino Marta
- van den Hoogen Bernadette
- Varsani Arvind
- Vasilakis Nikos
- Verbeek Martin
- von Bargen Susanne
- Wada Jiro
- Wahl Victoria
- Walker Peter J
- Walker Peter J.
- Wang Guoping
- Wang Lin-Fa
- Wang Yanxiang
- Wang Yaqin
- Waqas Muhammad
- Wen Shaohua
- Whitfield Anna E
- Whitfield Anna E.
- Williams John V
- Williams John V.
- Wolf Yuri I
- Wolf Yuri I.
- Wu Jiangxiang
- WĂši TĂ iyĂșn
- Xu Lei
- Yanagisawa Hironobu
- Yang Caixia
- Yang Zuokun
- Zerbini F Murilo
- Zerbini F. Murilo
- Zhai Lifeng
- Zhang Jinguo
- Zhang Song
- Zhang Yong-Zhen
- Zhang Zhe
- Zhou Xueping
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/12/2021
- Field of study
Correction to: 2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales. Archives of Virology (2021) 166:3567â3579. https://doi.org/10.1007/s00705-021-05266-wIn March 2021, following the annual International Committee on Taxonomy of Viruses (ICTV) ratification vote on newly proposed taxa, the phylum Negarnaviricota was amended and emended. The phylum was expanded by four families (Aliusviridae, Crepuscuviridae, Myriaviridae, and Natareviridae), three subfamilies (Alpharhabdovirinae, Betarhabdovirinae, and Gammarhabdovirinae), 42 genera, and 200 species. Thirty-nine species were renamed and/or moved and seven species were abolished. This article presents the updated taxonomy of Negarnaviricota as now accepted by the ICTV.This work was supported in part through Laulima Government Solutions, LLC prime contract with the US National Institute of Allergy and Infectious Diseases (NIAID) under Contract No. HHSN272201800013C. J.H.K. performed this work as an employee of Tunnell Government Services (TGS), a subcontractor of Laulima Government Solutions, LLC under Contract No. HHSN272201800013C. This work was also supported in part with federal funds from the National Cancer Institute (NCI), National Institutes of Health (NIH), under Contract No. 75N91019D00024, Task Order No. 75N91019F00130 to I.C., who was supported by the Clinical Monitoring Research Program Directorate, Frederick National Lab for Cancer Research. This work was also funded in part by Contract No. HSHQDC-15-C-00064 awarded by DHS S&T for the management and operation of The National Biodefense Analysis and Countermeasures Center, a federally funded research and development center operated by the Battelle National Biodefense Institute (V.W.); and NIH contract HHSN272201000040I/HHSN27200004/D04 and grant R24AI120942 (N.V., R.B.T.). S.S. acknowledges partial support from the Special Research Initiative of Mississippi Agricultural and Forestry Experiment Station (MAFES), Mississippi State University, and the National Institute of Food and Agriculture, US Department of Agriculture, Hatch Project 1021494. Part of this work was supported by the Francis Crick Institute which receives its core funding from Cancer Research UK (FC001030), the UK Medical Research Council (FC001030), and the Wellcome Trust (FC001030).S
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
- Ahmadi Alireza
- Ahmed Shahana
- Aimable Matthew
- Ainscough Rachael
- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
- Allen Nicole R.
- Allen Susan
- Allen Thaddeus
- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
- Ambrose Karen
- Ambrose Kerrie
- Amemiya Chris
- Amico-Keller Gina
- Amin Amita G.
- Anderson Mechele
- Anderson Scott
- Anderson Scott
- Andora Janice
- Andredesz Carol
- Andrew Robert
- Andrews Dan
- Andrews Daniel
- Andrews Neil
- Andrews Stephanie
- Andriese Tim
- Anthouard VĂ©ronique
- Antonarakis Stylianos E.
- Anyalebechi Vivian
- Aoki Norie
- Apostolou Sinoula
- Apweiler Eva
- Arachchi Harindra
- Arai Rie
- Arbery Hazel
- Arcaina Marlon
- Arcaina Terisita
- Archer Beth
- Arellano Andre
- Arellano-Jones Perry
- Armbruster Jeff
- Armstrong Jon
- Arredondo Dilrukshi P.
- Arredondo Heather Hope
- Artiguenave François
- Asakawa Shuichi
- Asakawa Teruyo
- Ash Gareth
- Ashcroft Kevin
- Ashurst Jennifer
- Ashwell Robert
- Ashworth Linda K.
- Aslanidis Cara
- Asomugha Chinwe O.
- Asuncion Lawreen
- Atkin Deborah
- Atkinson Andrea
- Atkinson Barry
- Attix Cristina
- Attwood John
- Aubin Keith
- Auger Katherine
- Austin Shannon Michelle
- Avila Aaron
- Avis Terry
- Ayele Mulu
- Babayan Primo
- Babbage Anne
- Babbage Sarah
- Bach Phil
- Bachatsang Pasang
- Bacon Joanne
- Badri Hummy
- Baertsch Robert
- Bagguley Claire
- Bailey Jonathan
- Bajorek Eva
- Baker Andrew
- Baker Dan
- Baker M.
- Baker Richard
- Bakis Michele
- Baldwin Jennifer
- Banda Michael
- Banerjee Ruby
- Bao Jingyue
- Bao Qiyu
- Bao Weidong
- Bao Weidong
- Baptiste Pertrice
- Barbaria Joseph A.
- Barbe Valérie
- Bardill Simon
- Barker Daniel
- Barker Darren
- Barker Gary
- Barlow Karen
- Baron Laurent
- Barrett Anika
- Bartlett Rebecca
- Basham Victoria
- Bashman David
- Basu Suba
- Bateman Alex
- Bates Karen
- Battles John
- Batzer Mark
- Baumgart Cornelia
- Baumohl Jason
- Baynes Caroline
- Bayul Tashi
- Beall Keith
- Beard Lisa
- Beard Susan
- Beare David
- Beasley Alastair
- Beasley Helen
- Beasley Oliver
- Beaucham Leslie
- Beaudet Arthur
- Beck Alfred
- Beck Stephen
- Becker Michael
- Bell Emma
- Bell George I.
- Bellard Terell M.
- Bellerby Damian
- Bellerby Tristram
- Belter Edward A., Jr.
- Bemrose Richard
- Benard Michael Anthony
- BenKahla Alia
- Benke J
- Benner William
- Bennett James
- Bensasson Douda
- Bentley Andrew
- Bentley Dan
- Bentley David
- Berardinis VĂ©ronique de
- Bercovitz John
- Berghoff Amy
- Bergmann Anne
- Berkowicz Nicolas
- Berks Mary
- Berks Michael
- Bethel Graeme
- Beugelsdijk Tony J.
- Bhakta Rita
- Bhuchar Venita
- Bi Shihua
- Bian Xuemeng
- Bieri Tamberlyn
- Bimage Kesha E.
- Bird Christine
- Birditt Brian
- Birney Ewan
- Birney Ewan
- Birren Bruce
- Bissell Helen
- Biswalo Kaneza
- Bituin Aleksandr
- Black Stacey
- Blackburne-Maze Suzanne
- Blair Jessica Anne
- Blakey Sarah
- Blanks Tia
- Blasiar Darin
- Blazej Robert
- Blitshsteyn Berta
- Blomstrom David B.
- Bloom Scott
- Bloom Toby
- Blumer Heather
- Blye Jason
- Blyth Peter R.
- Blöcker Helmut
- Boatright Elizabeth
- Boehm John
- Boen Juanan
- Boguslavskiy Leonid
- Bolton Christel
- Bolund Lars
- Bondoc Marnel
- Bonfield James
- Bonnett Ralph
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- Brandriff Brigitte F.
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- MacLean Christine
- Madabhushi Ramki
- Madu Renita C.
- Maeda Hideto
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- Maheshwari Manjula
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- Maltbie Mary I.
- Mangum Brian
- Manning Jonathan
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- Marabella Dick
- Mardis Elaine R.
- Mareth David
- Mariano Marisa
- Marinelli Lisa
- Mark Graham A.
- Marquis-Homeyer Catherine
- Marr Thomas G.
- Marra Marco
- Marriott Neil
- Marrone Anne
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- Matthews Charles D.
- Matthews Lucy
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- Matthews Sterling D.
- Mauceli Evan
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- McLeod Michael P.
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- McMurray Amanda
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- Meidi Patrick
- Meier Elke
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- Mejima Mio
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- Yang Xiaonan
- Yang Xiaonan
- Yang Xiaoping
- Yang Yongkui
- Yano Candance
- Yao Zhijian
- Yao Zhijian
- Yaspo Marie-Laure
- Ye Chen
- Yeager Shane
- Yeh Mimi
- Yen Jennifer
- Yeshitela Rahel Retta
- Yoakum Martin
- Yokobata Kathy
- Yokoyama Jennifer
- Yonezawa Miho
- Yoon Lillienne
- Yoon Vivienne
- Yoshida Satoru
- You Bo
- Young Geneva
- Young Louise
- Young Shelia
- Younger Ruth
- Yu Bing
- Yu Charles
- Yu Fuli
- Yu Jun
- Yu Jun
- Yu Jun
- Yuan Kaiwen
- Yuan Ye
- Yuan Yida
- Yue Shujie
- Yumae Brian
- Yun Rui
- Zainoun Joanne
- Zembeck Lisa
- Zeng Yixin
- Zhai Dong
- Zhan Guoping
- Zhang Bo
- Zhang Caimin
- Zhang Fengmei
- Zhang Guangyu
- Zhang Guohua
- Zhang Guohua
- Zhang Haiqing
- Zhang Haiqing
- Zhang Haiqing
- Zhang Hongbo
- Zhang Hongbo
- Zhang Jingjing
- Zhang Jingjing
- Zhang Jingkun
- Zhang Jiuchun
- Zhang Jiuchun
- Zhang Lanzhi
- Zhang Li
- Zhang Li
- Zhang Meihua
- Zhang Meng
- Zhang Ming
- Zhang Qing
- Zhang Ruhua
- Zhang Shaojie
- Zhang Tiezhen
- Zhang Wei
- Zhang Wei
- Zhang Xianglin
- Zhang Xianglin
- Zhang Xiaoliang
- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers âŒ99% of the euchromatic genome and is accurate to an error rate of âŒ1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales.
- Author
- Adkins Scott
- Agwanda Bernard R
- Al Kubrusli Rim
- Alkhovskiy Sergey V
- Amarasinghe Gaya K
- Avsic-Zupanc Tatjana
- AyllĂłn MarĂa
- Bahl Justin
- Balkema-Buschmann Anne
- Ballinger Matthew J
- Basler Christopher F
- Bavari Sina
- Beer Martin
- Bejerman Nicolas
- Bennett Andrew J
- Bente Dennis A
- Bergeron Ăric
- Bird Brian H
- Blair Carol D
- Blasdell Kim R
- Blystad Dag-Ragnar
- Bojko Jamie
- Borth Wayne B
- Bradfute Steven
- Breyta Rachel
- Briese Thomas
- Brown Judith K
- Brown Paul A
- Buchholz Ursula J
- Buchmeier Michael J
- Bukreyev Alexander
- Burt Felicity
- Buttner Carmen
- Calisher Charles H
- Cao Mengji
- Casas Inmaculada
- Chandran Kartik
- Charrel RĂ©mi N
- Cheng Qi
- Chiaki Yuya
- Chiapello Marco
- Choi II-Ryong
- Cicco Emiliano Di
- Ciuffo Marina
- Clegg J. Christopher S
- Crozier Ian
- Dal BĂł Elena
- Debat Humberto
- Dheilly Nolwenn M
- Dietzgen Ralf G
- Digiaro Michele
- Dolnik Olga
- Drebot Michael A
- Drexler J. Felix
- Dundon William G
- Duprex W. Paul
- Durrwald Ralf
- Dye John M
- Easton Andrew J
- Ebihara Hideki
- Elbeaino Toufic
- Ergunay Koray
- Ferguson Hugh W
- Fooks Anthony R
- Forgia Marco
- Formenty Pierre B. H
- Freitas-AstĂșa Juliana
- FrĂĄnovĂĄ Jana
- Fu Jingjing
- Furl Stephanie
- Gago-Zachert Selma
- Garcia MarĂa Laura
- Garrison Aura R
- Gaskin Thomas
- Goldberg Tony L
- Gonzalez Jean-Paul J
- Griffiths Anthony
- Groschup Martin H
- Gunther Stephan
- GĂŁo George FĂș
- Hall Roy A
- Hammond John
- Han Tong
- Hepojoki Jussi
- Hewson Roger
- Hong Jiang
- Hong Ni
- Hongo Seiji
- Hoogen Bernadette Van den
- Horie Masayuki
- Hu John S
- Hu Tao
- Hughes Holly R
- Huttner Florian
- Hyndman Timothy H
- IIyas Muhammad
- Jalkanen Risto
- JiĂŁng DĂ ohĂłng
- Jonson Gilda B
- Junglen Sandra
- Kadono Fujio
- Kaukinen Karia H
- Kawate Michael
- Klempa Boris
- Klingstrom Jonas
- Kobinger Gary
- Koloniuk Igor
- KondĂ” Hideki
- Koonin Eugene V
- Krupovic Mart
- Kubota Kenji
- Kuhn Jens H
- Kurath Gael
- Laenen Lies
- Lamballerie Xavier de
- Lambert Amy J
- Langevin Stanley L
- Lee Benhur
- Lefkowitz Elliot J
- Leroy Eric M
- Li JiĂ nrĂłng
- Li Longhui
- Li Shaorong
- Liu Huazhen
- Lukashevich Igor S
- Luna Gabriel Robles
- Maes Piet
- Marklewitz Marco
- Marshall Sergio H
- Marzano Shin-Yi L
- Massart Sebastien
- McCauley John W
- Melzer Michael
- Mielke-Ehret Nicole
- Miller Kristina M
- Ming Tobi J
- Mirazimi Ali
- Mordecai Gideon J
- Muhlbach Hans-Peter
- Muhlberger Elke
- Naidu Rayapati
- Natsuaki Tomohide
- Navarro José A
- Netesov Sergey V
- Neumann Gabriele
- Nowotny Norbert
- Nunes MĂĄrcio Roberto Teixeira
- Olmedo-Velarde Alejandro
- Palacios Gustavo
- PallĂĄs Vicente
- Paola Nicholas Di
- Papa Anna
- Paraskevopoulou Sofia
- Park Adam C
- Parrish Colin R
- Patterson David A
- Pauvolid-CorrĂȘa Alex
- Paweska Janusz T
- Payne Susan
- Peracchio Carlotta
- Postler Thomas S
- PĂĄlyi Bernadett
- PĂ©rez Daniel R
- Qi Liying
- Radoshitzky Sheli R
- Resende Renato O
- Reyes Carina A
- Rima Bertus K
- Romanowski Victor
- Rota Paul
- Rubbenstroth Dennis
- Rubino Luisa
- Runstadler Jonathan A
- Sabanadzovic Sead
- Sall Amadou Alpha
- Salvato Maria S
- Sang Rosemary
- Sasaya Takahide
- Sastre Adolfo Garcia
- Schulze Angela
- Schwemmle Martin
- Serio Francesco Di
- Shi Mang
- Shimomoto Yoshifumi
- Shirako Yukio
- ShĂ XiĂŁohĂłng
- ShĂ ZhĂšnglĂŹ
- Siddell Stuart G
- Simmonds Peter
- Sironi Manuela
- Smagghe Guy
- Smither Sophie
- Song Jin-Won
- Souza William Marciel de
- Spann Kirsten
- Spengler Jessica R
- Stenglein Mark D
- Stone David M
- Sugano Jari
- Suttle Curtis A
- Swart Rik L. de
- Tabata Amy
- Takada Ayato
- Takeuchi Shigeharu
- Tchouassi David P
- Teffer Amy
- Tesh Robert B
- Thornburg Natalie J
- Tomitaka Yasuhiro
- Tomnaga KeizĂ”
- Tordo Baldwyn
- Tordo Noel
- Torre Juan Carlos de la
- Towner Jonathan S
- Tsuda Shinya
- Tu Changchun
- Turina Massimo
- Tzanetakis Ioannis E
- Uchida Janice
- Usugi Tomio
- Vaira Anna Maria
- Vallino Marta
- Varsani Arvind
- Vasilakis Nikos
- Verbeek Martin
- Von Bargen Susanne
- Wada Jiro
- Wahl Victoria
- Walker Peter J
- Wang Guoping
- Wang Lin-Fa
- Wang Yanxiang
- Wang Yanxiang
- Wang Yaqin
- Waqas Muhammad
- Wen Shaohua
- Whitfield Anna E
- Williams John V
- Wolf Yuri I
- Wu Jiangxiang
- WĂši TĂ iyĂșn
- Xu Lei
- Yanagisawa Hironobu
- Yang Caixia
- Yang Zuokun
- Zerbini F. Murilo
- Zhai Lifeng
- Zhang Jinguo
- Zhang Song
- Zhang Yong-Zhen
- Zhang Zhe
- Zhou Xueping
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/12/2020
- Field of study
In March 2021, following the annual International Committee on Taxonomy of Viruses (ICTV) ratification vote on newly proposed taxa, the phylum Negarnaviricota was amended and emended. The phylum was expanded by four families (Aliusviridae, Crepuscuviridae, Myriaviridae, and Natareviridae), three subfamilies (Alpharhabdovirinae, Betarhabdovirinae, and Gammarhabdovirinae), 42 genera, and 200 species. Thirty-nine species were renamed and/or moved and seven species were abolished. This article presents the updated taxonomy of Negarnaviricota as now accepted by the ICTV
Proceedings of the 3rd Biennial Conference of the Society for Implementation Research Collaboration (SIRC) 2015: advancing efficient methodologies through community partnerships and team science
- Author
- Aarons Gregory A
- Achtmeyer Carol E
- Alia Kassandra A
- Andrews Jack H
- Aranda Maria P
- Arch Joanna J
- Au Janelle R
- Barac Raluca
- Barg Frances
- Barnett Miya
- Barwick Melanie
- Baumann Ana
- Beidas Rinad S
- Bennett Ian M
- Berger Douglas
- Berliner Lucy
- Best Helen
- Bickel John A
- Bishop Asia S
- Blonigen Daniel M
- Borah Elisa V
- Bory Christopher
- Botanov Yevgeny
- Botsko Christopher
- Boyd Meredith
- Brikho Brigitte
- Brookman-Frazee Lauren
- Brown Jacquie
- Brown Kimbree
- Bruns Eric J
- Bunger Alicia C
- Calhoun Patrick
- Campbell Dayna
- Campbell Mark
- Carlson Kathleen F
- Carroll Grace
- Carvalho Michelle
- Cevasco Molly
- Chamberlain Patricia
- Chen Tianying
- Chi Benjamin
- Chinman Matthew J
- Choy-Brown Mimi
- Clapp John D
- Coldiron Jennifer S
- Colditz Graham
- Combs Sonia
- Comtois Katherine A
- Conte Kathleen P
- Cooper Brittany R
- Cottrell Erika K
- Craske Michelle
- Cristaudo Katharine
- Crotwell Shirley
- Damschroder Laura J
- Damush Teresa M
- Darnell Doyanne
- Davidson Marnie
- Dishion Thomas D
- Dishion Thomas J
- Ditty Matthew S
- Dizon Eleanor
- Dondanville Katherine
- Dorsey Caitlin
- Dorsey Shannon
- Doyle Andrea
- Drahota Amy
- Duarte Cristiane
- DuBose Anthony
- Dwyer Andrea
- Edmunds Sarah R
- Ehrhart Mark. G
- Epstein Elizabeth
- Evans Arthur C
- Ezeanolue Echezona
- Fernandes Maria J
- Fernandez Maria E
- Filiatrault Johanne
- Finn Natalie K
- Fizur Phil
- Fleming Jennifer L
- Fox Dan
- Frank Anissa
- Franks Robert P
- Funaiole Angie
- Gamarra Jennifer
- Garcia Antonio R
- Gerke Donald R
- Gildred Tory
- Gius Becky
- Gold Rachel
- Graham Benjamin C
- Green Amy E
- Guay Laura
- Gutner Cassidy A
- Hadley Trevor R
- Hagedorn Hildi J
- Halko Heather
- Hallgren Kevin
- Hamilton Alison
- Hannah Gordon
- Hansen Marissa C
- Hanson Rochelle F
- Harker Colleen
- Harker Colleen M
- Harlin Zandrea
- Hartzler Bryan
- Hausman Estee M
- Hawkins Eric J
- Hawley Kristin M
- Hendricks Karin
- Heredia Natalia I
- Hernandez Armando
- Higa-McMillan Charmaine K
- Hill Kaitlin A
- Hinde Jesse M
- Hook Alyssa N
- Hurford Matthew O
- Ibañez Lisa V
- Ivanoff André
- Izmirian Sonia
- Jacobson Nora
- Johnides Benjamin D
- Jordan Katelin
- Jungbluth Nathaniel
- Karp Elizabeth A
- Karp Zaher
- Karuntzos Georgia T
- Kegler Michelle
- Keir Scott
- Kellar-Guenther Yvonne
- Kerns Suzanne
- Kerns Suzanne E U
- Kikuta Beverly
- Kim B.K. E
- Kim Minseop
- Kirchner JoAnn E
- Kline Lydia
- Korathu-Larson Priya A
- Korslund Kathryn E
- Kotte Amelia
- Krawczyk Noa
- Kritski AfrĂąnio
- Ladd Benjamin
- Lamont Andrea
- Landes Sara J
- Landsverk John
- Landy Meredith S
- Lane Jeanine
- Lau Anna
- LeBuffe Paul A
- Lewis Cara
- Lewis Cara C
- Lewis Ericka M
- Liang Shuting L
- Linehan Marsha M
- Lischner David H
- Litz Brett T
- Liu Freda
- Liu Nancy
- Locke Jill
- Lockhart Mariko
- Lorthios-Guilledroit Agathe
- Lott Aline
- Lovejoy Travis L
- Lowery Julie C
- Lucenko Barbara
- Lucid Leah
- Lyon Aaron R
- Mah Albert C
- Malte Carol A
- Mandell David
- Manfredi Luisa
- Mao Johnny
- Mariano Anthony J
- Marriott Brigid
- Marriott Brigid R
- Martinez Jonathan I
- Mastlej Marta
- Matlin Samantha L
- Matthieu Monica J
- Matthieu Monica M
- Mauricio Anne M
- McCaughan Stacey Y
- McCrady Barbara
- McGee-Vincent Pearl
- McWilliam Jenna
- Melvin Abigail
- Meza Rosemary D
- Miech Edward J
- Mintz Jim
- Mitchell Jill L
- Molino Alma
- Monroe-DeVita Maria
- Monson Candice M
- Moreland Angela
- Murray Laura K
- Muñoz Rosa
- Nakamura Brad J
- Nathanson Lori
- Navarro-Haro Marivi
- Negrete Andrea
- Nelligan Caitlin
- Nevedal Andrea
- Olsen Anne
- Ono Sarah S
- OâNeil Maya E
- OâSullivan Patricia
- Padgett Deborah K
- Palinkas Lawrence A
- Pandhi Nancy
- Pavelle Bridget
- Peterson Alan L
- Pierce Jennifer D
- Pierson Andria
- Powell Byron
- Powers Diane
- Proctor Enola K
- Prusaczyk Beth
- Pullmann Michael D
- Puspitasari Ajeng
- Ramos Karina
- Ramsey Alex
- Rawson Richard
- Ray Marilyn L
- Regan Jennifer
- Resick Patricia A
- Resnick Heidi S
- Richard Lucie
- Ries Richard
- Risendal Betsy
- Robertson Hillary A
- Rodriguez Allison L
- Roesch Scott
- Rosen Craig S
- Rosenthal Joel
- Roy-Byrne Peter
- Rubin Ronnie M
- Ruderman Danielle E
- Rudo-Stern Jenna
- Runnals Jennifer
- Saldana Lisa
- Salim Laila
- Santos Edilson
- Satre Derek
- Satterfield Jason
- Saunders Benjamin E
- Saxon Andrew J
- Schaper Holle
- Schmidt Janet
- Schreiter Elizabeth Z
- Schroeder Jennifer
- Scott Kelli
- Sedlar Georganna
- Segell Eliza
- Serrano Neftali
- Shapiro Valerie B
- Shaw Daniel S
- Shaw R. K
- Shephard Fredric
- Shields Norman
- Shingledecker Travis
- Siberry George
- Simmons Dena
- Smith Bikki T
- Smith Brandy N
- Smith Jeffrey L
- Smith Justin D
- Snowden Lonnie
- Sommerfeld David H
- Stadnick Nicole
- Stahmer Aubyn C
- Stanick Cameo
- Steffen Julie
- Steinfeld Bradley
- Stewart Rebecca E
- Stirman Shannon W
- Stone Wendy L
- Stormshak Elizabeth A
- Sturke Rachel
- Suvak Michael
- Sweetland Annika C
- Thompson Kelly
- Thornton Nicole
- Tiderington Emmy
- Torrente Catalina
- Torres Elisa M
- Torres-Vigil Isabel
- Trent Lindsay R
- Trott Elise M
- Tucker Michelle
- Tueller Stephen J
- Unutzer Jurgen
- Uomoto Jacqueline A
- Van Dorn Richard A
- Varkovitzky Ruth L
- Velasquez Susan
- Vogt Dawne
- Volpe Lane
- Vredevoogd Mindy
- Wachen Jennifer S
- Wainberg Milton L
- Walker Sarah C
- Walser Robyn
- Waltz Thomas J
- Wamsley Maria
- Wandersman Abraham
- Weaver Shawna L
- Weiner Bryan J
- Wietfeldt Natalie
- Willging Cathleen E
- Williamson Anna
- Wilson Melvin N
- Wiltsey-Stirman Shannon
- Wolitzky-Taylor Kate
- Wolk Courtney B
- Woolf Nicholas H
- Yarvis Jeffrey S
- Young Vicki
- Yuan Patrick
- Zlotkin Stanley
- Zounlome Nelson
- Publication venue
- BioMed Central
- Publication date
- 23/06/2016
- Field of study
It is well documented that the majority of adults, children and families in need of evidence-based behavioral health interventionsi do not receive them [1, 2] and that few robust empirically supported methods for implementing evidence-based practices (EBPs) exist. The Society for Implementation Research Collaboration (SIRC) represents a burgeoning effort to advance the innovation and rigor of implementation research and is uniquely focused on bringing together researchers and stakeholders committed to evaluating the implementation of complex evidence-based behavioral health interventions. Through its diverse activities and membership, SIRC aims to foster the promise of implementation research to better serve the behavioral health needs of the population by identifying rigorous, relevant, and efficient strategies that successfully transfer scientific evidence to clinical knowledge for use in real world settings [3]. SIRC began as a National Institute of Mental Health (NIMH)-funded conference series in 2010 (previously titled the âSeattle Implementation Research Conferenceâ; $150,000 USD for 3 conferences in 2011, 2013, and 2015) with the recognition that there were multiple researchers and stakeholdersi working in parallel on innovative implementation science projects in behavioral health, but that formal channels for communicating and collaborating with one another were relatively unavailable. There was a significant need for a forum within which implementation researchers and stakeholders could learn from one another, refine approaches to science and practice, and develop an implementation research agenda using common measures, methods, and research principles to improve both the frequency and quality with which behavioral health treatment implementation is evaluated. SIRCâs membership growth is a testament to this identified need with more than 1000 members from 2011 to the present.ii SIRCâs primary objectives are to: (1) foster communication and collaboration across diverse groups, including implementation researchers, intermediariesi, as well as community stakeholders (SIRC uses the term âEBP championsâ for these groups) â and to do so across multiple career levels (e.g., students, early career faculty, established investigators); and (2) enhance and disseminate rigorous measures and methodologies for implementing EBPs and evaluating EBP implementation efforts. These objectives are well aligned with Glasgow and colleaguesâ [4] five core tenets deemed critical for advancing implementation science: collaboration, efficiency and speed, rigor and relevance, improved capacity, and cumulative knowledge. SIRC advances these objectives and tenets through in-person conferences, which bring together multidisciplinary implementation researchers and those implementing evidence-based behavioral health interventions in the community to share their work and create professional connections and collaborations
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
- Author
- Aanniz Tarek
- Abar Aden Elmi
- Abbad Anass
- Abdelfattah May
- Abdelhamid W.
- Abdella Saro
- Abdellah Faouzi
- Abdelmjid El Oualid
- Abdelmoula Fatma
- Abdelmoulah F.
- Abderrahmane Maaroufi
- Abderrazak Rfaki
- Abdillahi Idil Salah
- Abdissa Alemseged
- Abdo I.
- Abdoelraheem Mohamed Hassan
- Abe Haruka
- Abebe Markos
- Abechi Priscilla
- Abera Adugna
- Abi Rachid
- Abias Abe G.
- Abichu Getachew
- Abid N.
- Abid Nabil
- Abid Salma
- Abilio Nuro
- Abimbola Sharon
- Abo Shama Noura M
- Abosede O.
- Aboubaker Mohamed Houmed
- Abouelhoda Mohamed
- Abouelnaga S.
- Abualas Elamin
- Abubeker Ramalia Chabi
- Abuelenein Ehab Abdelkader
- Abuzaid Nadir
- Abworo Edward O.
- Ada Diosdado Odjama Nseng
- Addidle Michael
- Adegbola Richard
- Adegnika Akim A.
- Adegnika Ayola Akim
- Adel Abd Monaem
- Adeniji Johnson A.
- Adepetun Tomiwa
- Adesegun A.
- Adesuyi Omoare
- Adetifa Ifedayo M. O.
- Adewumi Olubusuyi M.
- Adewumi Oluwatimilehin
- Adewumi Praise
- Adeyemi Kayode T.
- Adhikari Bishwo N.
- Adil El Hamouchi
- Adjiratou Aissatou B. A.
- Adnew Bethlehem
- Adu Bright
- Adu Eric
- Adusei-Poku Mildred
- Agbenyo Seyram Bless
- Agbodzi B.
- Ageez A.M.
- Agoti Charles N.
- Aguenaou Hassan
- Agwa Sara Hassan
- Agweyu Ambrose
- Ahmed El Bara
- Ahmed Elhadi A.
- Ahmed Hatem
- Ahmed M.
- Ahmed O. S.
- Ahmed Rahma
- Ahmed Shymaa S.
- Ahmed Side Mohamed
- Ahmed Yahaya Ali
- Ahouidi Ambroise
- Ahuka-Mundeke Steve
- Ahumibe Anthony
- Ahyong Vida
- Aissam El Aliani
- Ajayi Nnennaya A.
- Ajibaye Solomon
- Ajili F.
- Ajogbasile F.V.
- Ajogbasile Fehintola V.
- Akanbi Olusola Anuoluwapo
- Akenji Blaise MBoringong
- Akhoud Youssef
- Akinola Monilade
- Akogbeto Petas
- Akoua-Koffi Chantal G.
- Akpede George O.
- Al Onifade Fattah
- Alain Etoundi Mballa
- Alaoui Afaf
- Alaoui-Amine Sanaa
- Alarif Ahlam
- Alaruusi A. M.
- Albert MĂ©lanie
- AlEmam Adba Alfatih
- Alemayehu Dawit Hailu
- Alemu Fekadu
- Algheriani Raiva
- Ali Abraham
- Ali M.A.
- Ali Mohamed Ahmed
- Ali Mushal
- Ali Wael
- Alkarim Mona O.A.
- Allam Loubna
- Allam Mushal
- Allam Mushal
- Altamura Settimia
- Amar Narjis
- Amenga-Etego Lucas N.
- Amer K. E.
- Amer Khaled
- Amira Souissi
- Amoako Daniel G.
- Amoo Olufemi Samuel
- Amoth Patrick
- Amougou Marie
- Ampofo William K.
- Amuri Adrienne A.
- Amuzu Dominic S. Y.
- Amzazi SaaĂŻd
- Anang Abraham Kwabena
- Anas Abbad
- Andeko Julia C.
- Andersen Kristian
- Andersson Hana Sofia
- Andika Brian
- Andres Moreira-Soto
- Andriam Soa Fy
- Andriamandimby Soa Fy
- Anga Latifa
- Ange Dossou
- Angelov Angel
- Anna-Lena Sander
- Annajr B.
- Anoh Etilé A.
- Anscombe Catherine
- Antwerpen Markus H.
- Anu Campbell
- Anyaneji Ugochukwu J.
- Anyika Chinyere
- Aouni M.
- Appiah Vincent
- Appiah-Kubi Joyce
- Arena Fabio
- Arjaquah Augustina
- Arjarquah A.
- Armand Edang-Minko
- Armanious Riad Mounir
- Armoo Samuel
- Arnaldo Paulo
- Arnold Catherine E.
- Arrouchi Housna
- Artesi Maria
- Aryeetey Sherihane
- Asamoah Jesse Addo
- Asante Ivy A.
- Asare K.M.
- Ashton Philip
- Ashton Phillip
- Asiedu Ernest
- Asiedu-Bekoe Franklyn Egbe
- Asiimwe Stephen
- Askander Omar
- Asmamaw Kominist
- Assane Hamadi
- Assoumou Samira Zoa
- Atiga N.
- Attiku Keren Okyerebea
- Audu Rosemary A.
- Auld A.
- Awandare Gordon A.
- Awinda George
- Awunyo Sena
- Ayansola Oyeronke
- Ayei James
- Ayekaba Mitoha Ondoâo
- Ayivor-Djanie Reuben
- Aymane Bouzidi
- Ayo-Ale B.
- Ayoade F.
- Ayoola Joy
- Ayouba Ahidjo
- Aziz Ramy Karam
- Aziza Amuri
- Azman Andrew
- Aïssi Melchior A. Joël
- Ba-Diallo Awa
- Babatunde Sunday
- Baboo S. B.
- Badjo Ange
- Badou Yvette
- Bagaya Bernard Ssentalo
- Bah Mamadou Saliou
- Bahadoor B. S.
- Bahnassy A.A.
- Bajjou Tahar
- Baker David
- Baker Noah
- Bakhash Shah Mohamed
- Bakry U.
- Balde Aladje
- Balde Aladje
- Balm Michelle
- Bamourou Diané
- Banda R.
- Bane S.
- Barasa Edwine
- Barbet Marion
- Bareng Ontlametse T.
- Barilar Ivan
- Barkat Amina
- Barnes Kayla
- Barreh Guedi Ali
- Bashein Abdulla
- BassĂšne Hubert
- Batchi-Bouyou Armel L.
- Batchi-Bouyou Armel L.
- Bates Matthew
- Batra Dhwani
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- Bbosa Nicholas
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- Umumararungu Esperance
- Umuringa Jeanne dâArc
- Upton Arlo
- Ushijima Yuri
- Ussher James
- Utpatel Christian
- Uwanibe Jessica N.
- Uwituze Arlene
- van der Eijk Annemiek
- van der Linden Anne
- van der Linden Antje
- van der Werf Sylvie
- Van Rooyen G.
- van Rooyen Gerhard
- van Wyk Stephanie
- van Zyl Gert U.
- Vanaerschot M.
- Vanmechelen Bert
- Vanpeene Maud
- Velavan Thirumalaisamy P.
- Venter Marietjie
- Vernet Marie-Astrid
- Viana R.
- Vickos U.
- Victoir Kathleen
- Vida Ahyong
- Vidal Nicole
- Viegas Sofia
- Vincent Grace
- Vinze Anika
- Voegtly Logan J.
- von Gottberg Anne
- Waberi Zeinab Ali
- Wadi Amira Suliaman
- Wadonda N.
- Wadula J.
- Wagner Philipp
- Wahab Kolawole Wasiu
- Waitumbi John
- Walter Mathias C.
- Wamala Joseph F.
- Wandera Dennis N.
- Wang Jing
- Wang Xiuhua
- Wani Gregory
- Wanjohi Dorcas W.
- Wanok Stephen
- Waruhiu C.N.
- Waruhiu Cecilia
- Wasfi Fares
- Watters Chaselynn M.
- Wawina-Bokalanga Tony
- Wayengera Misaki
- Wayoro Oby
- Webby R.
- Webby Richard
- Weldemariam A.G.
- Weldemariam Atsbeha G.
- Werno Anja
- Wiley Michael R.
- Wilkinson David
- Wilkinson Eduan
- Williamson Carolyn
- Wilson Shannon
- Woelfel R.
- Wohl Shirlee
- Wolh S.
- Wolter Nicole
- Wuduri Zara
- Wulf Ben
- Wurie I.
- Wurie Isatta
- Xavier Joicymara S.
- Xiang Zuzheng
- Xie Hong
- Yadouleton Anges
- Yadouleton Yahya
- Yakout Mostfa
- Yandoko Rivalyn Nakoune
- Yang Qi
- Yao Kouadio T.
- Yassine Kasmi
- Yassine Zouheir
- Yasuda Jiro
- Yatassaye Bouna
- Yeboah C.
- Yeboah Richmond
- Yeboah-Manu Dorothy
- Yemi Bright K.
- Yiaba Cyrus
- Yiaba Warren Cyrus
- Yu Popova A.
- Yusuf Nyam Itse
- Yusuf Yacob Mohamed
- Zablon J. Matoke D.
- Zablon J.O.
- Zaher Tarek Refaat Elnagdy Raafat
- Zahra El Ansari Fatima
- Zahran Manal Hamdy
- Zekri Abdel-Rahman N.
- Zhang J.
- Zhou Pei
- Zinyowera Sekesai
- Zong Minko O.
- Zongo ArsĂšne
- Zorgani A.
- Zouaki Amal
- Zulu P.
- Zumla Ali
- Zumla Alimuddin
- Zuze Boitumelo
- Publication venue
- 'American Association for the Advancement of Science (AAAS)'
- Publication date
- 07/10/2022
- Field of study
INTRODUCTION
Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic.
RATIONALE
We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs).
RESULTS
Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants.
CONCLUSION
Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century
Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19
- Author
- ?ivko Iris
- Abbass Hakam
- Abdeladim Lilia
- Abdelhady Hesham
- Abdelkharim Hussam
- Abdelrazik Marwa
- Abdi Zakee
- Abdukahil Sheryl Ann
- Abel Lynn
- Abraham Jacinta
- Abrahamson Gail
- Abusamra Yousuf
- Aceto Romina
- Adams Nick
- Adams Peter
- Adebambo Olumide
- Adhikari Neill
- Adhikari Sheetal
- Affleck Julia
- Agha Gloria
- Aghemo Alessio
- Agno Ronan
- Ahmad Norfaizan
- Ain Quratul
- Ainscough Kate
- Ainsworth James
- Aitken Lindianne
- Akamp Ceren
- Al Enezi Farhan
- Al-Bassam Wisam
- Al-Beidh Farah
- Albert Martin
- Albrett Jonathan
- Alderman Meera
- Aldo Bonizzoni Matteo
- Alegria Ana
- Alessandro CarĂ Gianmarco
- Alexander Brian
- Alexander Peter
- Alfonso Jordan
- Ali Maryam
- Ali Murtaza
- Allam Hayat
- Allen Barbara
- Allen Louise
- Allibone Suzanne
- Almeshhedani Hasham
- AlQahtani Samah
- Alswaidan Lolowa
- Altomy Mohammed
- Al Amri Ali
- Al Qasim Eman
- Amatya Sameena
- Ambrosino Richard
- Anderson Thomas
- Andreae Mark
- Aneman Anders
- Angus Derek C.
- Anjum Aisha
- Ankert Juliane
- Annane Djillali
- Anne-Laure Fedou
- Anstey Matthew
- Antcliffe David
- Anthony Alpha
- Antoine Marchalot
- Antoine Pierre
- Antoine Studer
- Anumakonda Vikram
- Aparicio Christelle
- Aquino Maia
- Arabi Yaseen M.
- Arachchige Malka
- Aravindan Latha
- Arbane Gill
- Archambault Patrick
- Archer Simon
- Aref Noah
- Arias Ana-Marie
- Arias Sonia
- Arishi Hatim
- Arnold Donald
- Arnold John
- Arnott Andrew
- Arora Anand
- Aryal Diptesh
- Asghar Adeeba
- Asif Namra
- Aspinwall Angelique
- Attokaran Antony
- Attwood Ben
- Au Carly
- Audry Mathilde
- Austin Karen
- Austin Pauline
- Auvet Adrien
- Avard Bronwyn
- Awan Sidra
- Ayee Robert
- Azaiz Amine
- Azzaui Harun
- Babu Suresh
- Bacon Gina
- Badalamenti Salvatore
- Badie Julio
- Bagavathy Kavitha
- Bagot Catherine
- Bagshaw Sean
- Baig Nadia
- Baikady Ravishankar
- Bailey Lucy
- Baillie Kenneth
- Bain William
- Baker Alice
- Baker Evelyn
- Baker Stuart
- Bakthavatsalam Dhanalakshmi
- Balaie Morteza
- Balls-Burgess Sam
- Bamford Amy
- Bamford Peter
- Banach Dorota
- Bannard-Smith Jonathan
- Barbash Ian
- Barber Russell
- Barbier François
- Barge Deborah
- Bariola Ryan
- Barker Gareth
- Barker Stephanie
- Barnes Nicky
- Baron Rebecca M.
- Barreau Amelie
- Barreau Amélie
- Bart Robert
- Bartholomew Jazz
- Bartley Shauna
- Barton David
- Barton Frances
- Bashyal Archana
- Basile Kim
- Bass Frances
- Bassford Christopher
- Bastos Joana Margarida Pereira Sousa
- Bates Michelle
- Bates Samantha
- Batista Teresa Margarida Oliveira
- Bauchmuller Kris
- Bayne Madeleine
- Bean Sarah
- Beane Abi
- Beane Abigail
- Beard Gregory
- Beasley Richard
- Beaudoin Rosalie
- Beavis Sarah
- Beddows Seonaid
- Bedford Caroline
- Beer Deborah
- Beer Sally
- Begin Phillipe
- Begum Salma
- Bell Gillian
- Bellemare David
- Belletti Allesandro
- Bendjemar Lynda
- Benettaib Fatna
- Bensen Nicole
- Bentley Andrew
- Benyon Sarah
- Benzekri Dalila
- Beqai Besa
- Berdaguer Fernando
- Beresford Stephanie
- Bergin Colin
- Berry Lindsay R.
- Berry Scott
- Berryman Emily
- Bertel Melanie
- Best-Lane Janis
- Besten Henny
- Bevan Emily
- Bewley Jeremy
- Beyerl Ashley
- Bhagani Sanjay
- Bhandal Khushpreet
- Bharaj Kiranjit
- Bhattarai Bina
- Bhattarai Binita
- Bhonagiri Deepak
- Biddie Simon
- Bigas Judit
- Bihari Shailesh
- Bin Hasan Mohd Shahnaz
- Bindels Manon
- Binnie Alexandra
- Biradar Vishwanath
- Birch Catherine
- Birch Janine
- Birch Sophie
- Birchall Kathrine
- Birkinshaw Isobel
- Black Ethel
- Blackledge Bethany
- Blakemore Hayley
- Blanck Wendy
- Bland Yvonne
- Blank Elisabeth
- Bleasdale John
- Bloomfield Jack
- Bloos Frank
- Board Jasmin
- Boardman Melanie
- Boari Gianluca
- Bocher Simon
- Bociek Aneta
- Boivin Anne-Helene
- Boivin Anne-HĂ©lĂšne
- Bojunga Jörg
- Bomken Charlotte
- Bonaccorso Allesandra
- Bongaerts Katherine
- Bonner Stephen
- Bonten Marc J. M.
- Borgatta Barbara
- Borislavova Borislava
- Borrill Zoe
- Boschert Catherine
- Bossard Isabelle
- Bothma Pieter
- Boudineau Michel
- Boulanger Marie-Claude
- Boumahni Dounia
- Bouman Angela
- Bounab Rania
- Bourgoin Charlotte
- Bourne Michelle
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- Bradbury Charlotte A.
- Bradley Paul
- Brady Kara
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- Brunkhorst Frank M.
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- de Groot Klaas
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- Depuydt Pieter
- Dequin Pierre-François
- Derde Lennie P. G.
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- Detry Michelle A.
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- de la Fuente Carmen
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- Ebenezer R
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- Higgins Alisa M.
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- Horvat Christopher M.
- Howcroft Clare
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- Hoxha Elvira
- Huang David T.
- Hughes Debbie
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- Kremling Julius
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- Krishnamoorthy S
- Krishnamurthy Vinodh
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- Le Basnier Elliot
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- McGuinness Shay P.
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- Xavier Kugan
- Yamagishi Yoshiaki
- Yamashita Chizuru
- Yang Yang
- Yarad Elizabeth
- Yates Bryan
- Yates David
- Yealy Donald
- Young Ian
- Young Meredith
- Young Paul
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- Yu Haili
- Yusuff Hakeem
- Zaharia Mihaela
- Zaidi Abbas
- Zaki Ahmed
- Zaman Mohsin
- Zarychanski Ryan
- Zdanavidiene Ausra
- Zhao Xiao
- Zinzoni Vanessa
- Zitter Letizia
- Zouita Louisa
- Publication venue
- 'American Medical Association (AMA)'
- Publication date
- 11/04/2023
- Field of study
IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19.
Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19.
DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 nonâcritically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022).
INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (nâ=â257), ARB (nâ=â248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; nâ=â10), or no RAS inhibitor (control; nâ=â264) for up to 10 days.
MAIN OUTCOMES AND MEASURES The primary outcome was organ supportâfree days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes.
RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ supportâfree days among critically ill patients was 10 (â1 to 16) in the ACE inhibitor group (nâ=â231), 8 (â1 to 17) in the ARB group (nâ=â217), and 12 (0 to 17) in the control group (nâ=â231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ supportâfree days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively).
CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes.
TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570