Proyecto de remodelación urbanística de la calle Sagarra del municipio de Santa Coloma de Gramenet

El Ayuntamiento de Santa Coloma de Gramenet, tiene en proyecto promover el barrio del Centro asignando una zona de comercio y ocio a los alrededores de la calle Sagarra, incluyendo ésta misma. Por ello, se está llevando a término una campaña de remodelación urbanística y mejora de viales con la voluntad de favorecer la circulación de peatones respecto a la de vehículos. Dada esta voluntad, este proyecto modificará la sección actual del vial, ensanchando las aceras, eliminando en su mayoría toda zona de estacionamiento (exceptuando los alrededores de la plaza donde se habilitará zona de carga y descarga), y se pretende suprimir todo tipo de barrera arquitectónica.Los principales objetivos son: · Dar protagonismo a los peatones creando zonas de prioridad de éstos sobre los vehículos, procurando la continuidad de los flujos ya existentes, y limitando la velocidad de los vehículos en la zona. · Ofrecer una urbanización diferenciada y que sea coherente, teniendo en cuenta los usos existentes y futuros; y mejorar estéticamente las zonas maltrechas. · Mejorar la red de servicios urbanísticos. · Utilizar materiales de bajo impacto ambiental, que sea fácil de mantener y reponer; y minimizar la contaminación lumínica siguiendo unos criterios de sostenibilidad

Flow Disruptions as a Result of Personal Electronic Devices in Orthopedic Surgery

The operating room (OR) is a complex environment in which highly trained individuals perform cognitively demanding tasks. Distractions in this environment may lead to deleterious effects, as a loss of situational awareness can interfere with surgical procedures. The present study aims to quantify the frequency and nature of distracting events associated with personal electronic devices (PEDs) during twenty elective orthopedic surgery cases. PED use was coded using a real-time, custom data collection tool beginning in the pre-operative area and terminating at the time of handoff with the post-anesthesia care team. PED use accounted for 242 flow disruptions in the OR. The vendor showed the highest frequency of flow disruptions (73), followed by the circulating nurse (52) and the certified registered nurse anesthetist (CRNA) (52). Thus, taking a proactive safety approach to account for intraoperative distractions associated with PEDs among OR team members will be critical to ensure high-quality patient care

Supramolecular Isomerism in Cobalt(II) Coordination Polymers Built from 3,5-Bis(trifluoromethyl)benzoate and 4,4'-Bipyridine

Acord transformatiu CRUE-CSICThe reaction of [Co2(H2O)(TFMBz)4(py)4] (1) (TFMBz: 3,5-bis(trifluoromethyl)benzoate; py: pyridine) with 4,4'-bipyridine (bpy) in different solvents yields four coordination polymers with unlikely structures but with the same stoichiometry. Three of them contain similar ladder chains consisting of binuclear nodes "Co2(TFMBz)4", in which two of the TFMBz ligands show bidentate bridge coordination, double linked to each adjacent node by bpy but packed in different fashions. The different packing affects the compound porosity; thus, [Co2(TFMBz)4(bpy)2]n (2), precipitated using low-polarity solvents such as supercritical CO2 (scCO2), n-butyl acetate, or heptane and also in acetonitrile, is microporous, with a surface area of 330 m2 g-1, showing the N2 adsorption/desorption isotherm at 77 K with a gate-opening effect at low relative pressures (P/P0 = 0.05). The isomer [Co2(TFMBz)4(bpy)2]n (3), synthesized in ethoxyethanol, presents a surface area of 230 m2 g-1. A third chain packing isomer, [Co2(TFMBz)4(bpy)2]n (4), is obtained in acetone and has only non-interconnected voids. Finally, precursor 1 is combined with bpy in a highly polar solvent such as water to give [Co(TFMBz)2(bpy)]n (5). In this isomer, all the carboxylate units act as bidentate bridging ligands, generating chains that are interlinked by bpy, leading to a 2D network, which after packing yields a non-porous structure. The resolution of structures 2-5 is only possible with the recently developed 3D electron diffraction method based on the collection of diffraction patterns on sub-micron-sized single crystals. The variation of magnetic susceptibility as a function of temperature is also measured. Overall, our work provides insightful information on the complex landscape of metal-organic framework solids that are formed by crystallization using different solvent media

Arabidopsis Squalene Epoxidase 3 (SQE3) Complements SQE1 and Is Important for Embryo Development and Bulk Squalene Epoxidase Activity

The existence of multigenic families in the mevalonate pathway suggests divergent functional roles for pathway components involved in the biosynthesis of plant sterols. Squalene epoxidases (SQEs) are key components of this pathway, and Squalene Epoxidase 1 (SQE1) has been identified as a fundamental enzyme in this biosynthetic step. In the present work, we extended the characterization of the remaining SQE family members, phylogenetically resolving between true SQEs and a subfamily of SQE-like proteins that is exclusive to Brassicaceae. Functional characterization of true SQE family members, Squalene Epoxidase 2 (SQE2) and Squalene Epoxidase 3 (SQE3), indicates that SQE3, but not SQE2, contributes to the bulk SQE activity in Arabidopsis, with sqe3-1 mutants accumulating squalene and displaying sensitivity to terbinafine. We genetically demonstrated that SQE3 seems to play a particularly significant role in embryo development. Also, SQE1 and SQE3 both localize in the endoplasmic reticulum, and SQE3 can functionally complement SQE1. Thus, SQE1 and SQE3 seem to be two functionally unequal redundant genes in the promotion of plant SQE activity in Arabidopsis.This work was supported by Ministerio de Ciencia e Innovación, co-financed by the European Regional Development Fund (BIO2011-23859 to M.A.B.). This work was also supported by Fundação para a Ciência e Tecnologia (SFRH/BD/29778/2006 to S.L.). H.A. was supported by the Genomics and Evolutionary Biology project, co-financed by North Portugal Regional Operational Programme 2007/2013 (ON.2 – O Novo Norte), under the National Strategic Reference Framework (NSRF), through the European Regional Development Fund (ERDF). A.R. was supported by the NSERC Discovery Grant (RGPIN-2014-06468) and funds from the Canada Research Chair

Facile, fast and green synthesis of a highly porous calcium-syringate bioMOF with intriguing triple bioactivity

A facile, fast and green strategy based on ethanol is utilized to prepare a new bioMOF, namely, CaSyr-1, with particular characteristics of full biocompatibility given by using just calcium and syringic acid, the latter being a phenolic natural product found in fruits and vegetables, permanent porosity with an outstanding surface area >1000 m2 g−1, and a micropore diameter of 1.4 nm close to mesopore values. Collectively, these data establish CaSyr-1 as one of the most porous bioMOFs reported to date, with high molecular adsorption capacity. The CaSyr-1 adsorptive behavior is revised here through the reversible adsorption of CO2 and the encapsulation of bioactive ingredients in the structure. Remarkably, CaSyr-1 enables the development of triple therapeutic entities, involving bioactive Ca2+, syringic acid and an impregnated drug

The GeV to TeV connection in the environment of SNR IC 443

We have recently interpreted the source MAGIC J0616+225 as a result of delayed TeV emission of cosmic-rays diffusing from IC 443 and interacting with a cloud in the foreground of the remnant. This model was used to make predictions for future observations, especially those to be made with the Fermi satellite. Just recently, AGILE, Fermi, and VERITAS have released new results of their observations of IC 443. In this work, we compare them with the predictions of our model, exploring the GeV to TeV connection in this region of space. We use Fermi data to consider the possibility of constraining the cosmic-ray diffusion features of the environment. We analyze the cosmic-ray distributions, their interactions, and a possible detection of the SNR environment in the neutrino channel.Comment: Accepted for publication in MNRAS. 20 pages, 10 figures, 1 tabl

Cavity of Molecular Gas Associated with Supernova Remnant 3C 397

3C 397 is a radio and X-ray bright Galactic supernova remnant (SNR) with an unusual rectangular morphology. Our CO observation obtained with the Purple Mountain Observatory at Delingha reveals that the remnant is well confined in a cavity of molecular gas, and embedded at the edge of a molecular cloud (MC) at the local standard of rest systemic velocity of ~32 km/s. The cloud has a column density gradient increasing from southeast to northwest, perpendicular to the Galactic plane, in agreement with the elongation direction of the remnant. This systemic velocity places the cloud and SNR 3C 397 at a kinematic distance of ~10.3 kpc. The derived mean molecular density (~10-30 cm^-3) explains the high volume emission measure of the X-ray emitting gas. A 12CO line broadening of the ~32 km/s component is detected at the westmost boundary of the remnant, which provides direct evidence of the SNR-MC interaction and suggests multi-component gas there with dense (~10^4 cm^-3) molecular clumps. We confirm the previous detection of a MC at ~38 km/s to the west and south of the SNR and argue, based on HI self-absorption, that the cloud is located in the foreground of the remnant. A list of Galactic SNRs presently known and suggested to be in physical contact with environmental MCs is appended in this paper.Comment: ApJ in press, 11 pages, 8 figures and 2 tables. A list of Galactic SNRs in physical contact with molecular clouds is included; it is updated in Ver.

Lecciones básicas de Derecho e instituciones de la Unión Europea

Los materiales docentes que aquí se presentan pretenden ser un texto de ayuda y consulta para aquellos que se acercan al Derecho de la Unión Europea; en ellos no sólo se contienen los conceptos básicos de la materia, sino que se han añadido a éstos, una serie de actividades didácticas y formativas específicamente orientadas al estudiante, y que le han de servir como instrumento para poder asentar sus conocimientos mediante la realización de prácticas y autoevaluaciones.The teaching materials presented here are intended as a help text and consultation for those who come to the European Union law; they not only contain the basic concepts of matter, but that have been added to these, a series of educational activities and training specifically geared toward the student, and that you have to serve as the instrument to be able to hone their knowledge through practical work and self-evaluations

Cellular Senescence in Livers from Children with End Stage Liver Disease

Senescent cells occur in adults with cirrhotic livers independent of the etiology. Aim: Investigate the presence rate of cellular senescence and expression of cell cycle check points in livers from children with end stage disease. staining occurred in the areas of ductular transformation and in the interlobular bile ducts.Cellular senescence in livers of children with end stage disease is associated with damage rather than corresponding to an age dependent phenomenon. Further studies are needed to support the hypothesis that these senescence markers correlate with disease progression

Follow-up study on lead exposure in children living in a smelter community in northern Mexico

<p>Abstract</p> <p>Background</p> <p>To study the changes of children lead exposure in the city of Torreon during the last five years, after environmental and public health interventions, using the timeline of lead in blood concentration as the biomarker of exposure and its relation to lead in soil concentrations.</p> <p>Methods</p> <p>This follow-up study started in 2001 and consisted of 232 children living in nine neighborhoods in Torreon. Children were tested at 0, 6, 12 and 60 months. Lead in blood concentrations, Hemoglobin, Zinc-Protoporphyrin, anthropometric measures and socioeconomic status questionnaire was supplied to the parents.</p> <p>Results</p> <p>Median and range of lead in blood concentrations obtained at 0, 6, 12, 60 months were: 10.12 μg/dl (1.9 - 43.8), 8.75 μg/dl (1.85 - 41.45), 8.4 μg/dl (1.7 - 35.8) and 4.4 μg/dl (1.3 - 30.3), respectively. The decrease of lead in blood levels was significantly related to ages 0, 6, 12 and 60 months of the follow-up study. The timeline of B-Pb was associated with the timeline of lead in soil concentrations.</p> <p>Conclusions</p> <p>B-Pb levels have significantly decreased in the group of children studied. This could be explained by a) environmental interventions by authorities and the smelter companies, b) normal changes in hygienic habits as children age and c) lead redistribution from blood to hard tissues.</p