40 research outputs found
PercepciĂłn de la educaciĂłn personalizada en una instituciĂłn educativa privada de Lima Metropolitana, 2019
El objetivo general del trabajo de investigaciĂłn fue conocer las percepciones de la educaciĂłn
personalizada en los estudiantes, padres de familia y docentes, para lo cual estĂĄ basado en
enfoque cualitativo, diseño narrativo, utilizåndose como muestra de seis estudiantes, seis
padres de familias y seis docentes de la ciudad de Lima, PerĂș, con la finalidad de conocer
los resultados y alcances de la aplicaciĂłn de la educaciĂłn personalizada como metodologĂa
de enseñanza. En el presente trabajo de investigación se utilizó instrumentos como la
entrevista y cuestionarios, con el resultado general que la educaciĂłn personalizada interviene
en el desarrollo personal del alumno de manera positiva, a través de educación integral en
valores que es realizada mediante un acompañamiento de la preceptora, a través del trabajo
en equipo con los padres de familia; la conclusiĂłn general del trabajo de investigaciĂłn fue
que la educaciĂłn personalizada es una educaciĂłn integral centrada en las particularidades de
cada estudiante y se evidencia a travĂ©s de la preceptorĂa comentada por los padres de
familias, estudiantes y docentes; ademĂĄs se recomienda realizar mĂĄs investigaciones con
enfoque cuantitativo o cualitativo sobre la aplicaciĂłn de la educaciĂłn personalizada y sus
efectos en el aprendizaje de los estudiantes, ya que actualmente existen escazas
investigaciones, libros, revistas o entrevistas actualizadas respecto al presente tema
Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2
The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality
Detailed stratified GWAS analysis for severe COVID-19 in four European populations
Given the highly variable clinical phenotype of Coronavirus disease 2019 (COVID-19), a deeper analysis of the host genetic contribution to severe COVID-19 is important to improve our understanding of underlying disease mechanisms. Here, we describe an extended genome-wide association meta-analysis of a well-characterized cohort of 3255 COVID-19 patients with respiratory failure and 12â488 population controls from Italy, Spain, Norway and Germany/Austria, including stratified analyses based on age, sex and disease severity, as well as targeted analyses of chromosome Y haplotypes, the human leukocyte antigen region and the SARS-CoV-2 peptidome. By inversion imputation, we traced a reported association at 17q21.31 to a ~0.9-Mb inversion polymorphism that creates two highly differentiated haplotypes and characterized the potential effects of the inversion in detail. Our data, together with the 5th release of summary statistics from the COVID-19 Host Genetics Initiative including non-Caucasian individuals, also identified a new locus at 19q13.33, including NAPSA, a gene which is expressed primarily in alveolar cells responsible for gas exchange in the lung.S.E.H. and C.A.S. partially supported genotyping through a philanthropic donation. A.F. and D.E. were supported by a grant from the German Federal Ministry of Education and COVID-19 grant Research (BMBF; ID:01KI20197); A.F., D.E. and F.D. were supported by the Deutsche Forschungsgemeinschaft Cluster of Excellence âPrecision Medicine in Chronic Inflammationâ (EXC2167). D.E. was supported by the German Federal Ministry of Education and Research (BMBF) within the framework of the Computational Life Sciences funding concept (CompLS grant 031L0165). D.E., K.B. and S.B. acknowledge the Novo Nordisk Foundation (NNF14CC0001 and NNF17OC0027594). T.L.L., A.T. and O.Ă. were funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), project numbers 279645989; 433116033; 437857095. M.W. and H.E. are supported by the German Research Foundation (DFG) through the Research Training Group 1743, âGenes, Environment and Inflammationâ. L.V. received funding from: Ricerca Finalizzata Ministero della Salute (RF-2016-02364358), Italian Ministry of Health âCV PREVITALââstrategie di prevenzione primaria cardiovascolare primaria nella popolazione italiana; The European Union (EU) Programme Horizon 2020 (under grant agreement No. 777377) for the project LITMUS- and for the project âREVEALâ; Fondazione IRCCS Caâ Granda âRicerca correnteâ, Fondazione Sviluppo Caâ Granda âLiver-BIBLEâ (PR-0391), Fondazione IRCCS Caâ Granda â5permilleâ âCOVID-19 Biobankâ (RC100017A). A.B. was supported by a grant from Fondazione Cariplo to Fondazione Tettamanti: âBio-banking of Covid-19 patient samples to support national and international research (Covid-Bank). This research was partly funded by an MIUR grant to the Department of Medical Sciences, under the program âDipartimenti di Eccellenza 2018â2022â. This study makes use of data generated by the GCAT-Genomes for Life. Cohort study of the Genomes of Catalonia, FundaciĂł IGTP (The Institute for Health Science Research Germans Trias i Pujol) IGTP is part of the CERCA Program/Generalitat de Catalunya. GCAT is supported by AcciĂłn de DinamizaciĂłn del ISCIII-MINECO and the Ministry of Health of the Generalitat of Catalunya (ADE 10/00026); the AgĂšncia de GestiĂł dâAjuts Universitaris i de Recerca (AGAUR) (2017-SGR 529). M.M. received research funding from grant PI19/00335 AcciĂłn EstratĂ©gica en Salud, integrated in the Spanish National RDI Plan and financed by ISCIII-SubdirecciĂłn General de EvaluaciĂłn and the Fondo Europeo de Desarrollo Regional (European Regional Development Fund (FEDER)-Una manera de hacer Europaâ). B.C. is supported by national grants PI18/01512. X.F. is supported by the VEIS project (001-P-001647) (co-funded by the European Regional Development Fund (ERDF), âA way to build Europeâ). Additional data included in this study were obtained in part by the COVICAT Study Group (Cohort Covid de Catalunya) supported by IsGlobal and IGTP, European Institute of Innovation & Technology (EIT), a body of the European Union, COVID-19 Rapid Response activity 73A and SR20-01024 La Caixa Foundation. A.J. and S.M. were supported by the Spanish Ministry of Economy and Competitiveness (grant numbers: PSE-010000-2006-6 and IPT-010000-2010-36). A.J. was also supported by national grant PI17/00019 from the AcciĂłn EstratĂ©gica en Salud (ISCIII) and the European Regional Development Fund (FEDER). The Basque Biobank, a hospital-related platform that also involves all Osakidetza health centres, the Basque governmentâs Department of Health and Onkologikoa, is operated by the Basque Foundation for Health Innovation and Research-BIOEF. M.C. received Grants BFU2016-77244-R and PID2019-107836RB-I00 funded by the Agencia Estatal de InvestigaciĂłn (AEI, Spain) and the European Regional Development Fund (FEDER, EU). M.R.G., J.A.H., R.G.D. and D.M.M. are supported by the âSpanish Ministry of Economy, Innovation and Competition, the Instituto de Salud Carlos IIIâ (PI19/01404, PI16/01842, PI19/00589, PI17/00535 and GLD19/00100) and by the Andalussian government (Proyectos EstratĂ©gicos-Fondos Feder PE-0451-2018, COVID-Premed, COVID GWAs). The position held by Itziar de Rojas Salarich is funded by grant FI20/00215, PFIS Contratos Predoctorales de FormaciĂłn en InvestigaciĂłn en Salud. Enrique CalderĂłnâs team is supported by CIBER of Epidemiology and Public Health (CIBERESP), âInstituto de Salud Carlos IIIâ. J.C.H. reports grants from Research Council of Norway grant no 312780 during the conduct of the study. E.S. reports grants from Research Council of Norway grant no. 312769. The BioMaterialBank Nord is supported by the German Center for Lung Research (DZL), Airway Research Center North (ARCN). The BioMaterialBank Nord is member of popgen 2.0 network (P2N). P.K. Bergisch Gladbach, Germany and the Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, Cologne, Germany. He is supported by the German Federal Ministry of Education and Research (BMBF). O.A.C. is supported by the German Federal Ministry of Research and Education and is funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germanyâs Excellence StrategyâCECAD, EXC 2030â390661388. The COMRI cohort is funded by Technical University of Munich, Munich, Germany. This work was supported by grants of the Rolf M. Schwiete Stiftung, the Saarland University, BMBF and The States of Saarland and Lower Saxony. K.U.L. is supported by the German Research Foundation (DFG, LU-1944/3-1). Genotyping for the BoSCO study is funded by the Institute of Human Genetics, University Hospital Bonn. F.H. was supported by the Bavarian State Ministry for Science and Arts. Part of the genotyping was supported by a grant to A.R. from the German Federal Ministry of Education and Research (BMBF, grant: 01ED1619A, European Alzheimer DNA BioBank, EADB) within the context of the EU Joint ProgrammeâNeurodegenerative Disease Research (JPND). Additional funding was derived from the German Research Foundation (DFG) grant: RA 1971/6-1 to A.R. P.R. is supported by the DFG (CCGA Sequencing Centre and DFG ExC2167 PMI and by SH state funds for COVID19 research). F.T. is supported by the Clinician Scientist Program of the Deutsche Forschungsgemeinschaft Cluster of Excellence âPrecision Medicine in Chronic Inflammationâ (EXC2167). C.L. and J.H. are supported by the German Center for Infection Research (DZIF). T.B., M.M.B., O.W. und A.H. are supported by the Stiftung UniversitĂ€tsmedizin Essen. M.A.-H. was supported by Juan de la Cierva Incorporacion program, grant IJC2018-035131-I funded by MCIN/AEI/10.13039/501100011033. E.C.S. is supported by the Deutsche Forschungsgemeinschaft (DFG; SCHU 2419/2-1).Peer reviewe
Detailed stratified GWAS analysis for severe COVID-19 in four European populations
Given the highly variable clinical phenotype of Coronavirus disease 2019 (COVID-19), a deeper analysis of the host genetic contribution to severe COVID-19 is important to improve our understanding of underlying disease mechanisms. Here, we describe an extended GWAS meta-analysis of a well-characterized cohort of 3,260 COVID-19 patients with respiratory failure and 12,483 population controls from Italy, Spain, Norway and Germany/Austria, including stratified analyses based on age, sex and disease severity, as well as targeted analyses of chromosome Y haplotypes, the human leukocyte antigen (HLA) region and the SARS-CoV-2 peptidome. By inversion imputation, we traced a reported association at 17q21.31 to a highly pleiotropic âŒ0.9-Mb inversion polymorphism and characterized the potential effects of the inversion in detail. Our data, together with the 5th release of summary statistics from the COVID-19 Host Genetics Initiative, also identified a new locus at 19q13.33, including NAPSA, a gene which is expressed primarily in alveolar cells responsible for gas exchange in the lung.Andre Franke and David Ellinghaus were supported by a grant from the German
Federal Ministry of Education and Research (01KI20197), Andre Franke, David
Ellinghaus and Frauke Degenhardt were supported by the Deutsche
Forschungsgemeinschaft Cluster of Excellence âPrecision Medicine in Chronic
Inflammationâ (EXC2167). David Ellinghaus was supported by the German Federal
Ministry of Education and Research (BMBF) within the framework of the
Computational Life Sciences funding concept (CompLS grant 031L0165). David
Ellinghaus, Karina Banasik and SĂžren Brunak acknowledge the Novo Nordisk
Foundation (grant NNF14CC0001 and NNF17OC0027594). Tobias L. Lenz, Ana
Teles and Onur Ăzer were funded by the Deutsche Forschungsgemeinschaft (DFG,
German Research Foundation), project numbers 279645989; 433116033; 437857095. Mareike Wendorff and Hesham ElAbd are supported by the German
Research Foundation (DFG) through the Research Training Group 1743, "Genes,
Environment and Inflammation". This project was supported by a Covid-19 grant from
the German Federal Ministry of Education and Research (BMBF; ID: 01KI20197).
Luca Valenti received funding from: Ricerca Finalizzata Ministero della Salute RF2016-02364358, Italian Ministry of Health ""CV PREVITAL â strategie di prevenzione
primaria cardiovascolare primaria nella popolazione italiana; The European Union
(EU) Programme Horizon 2020 (under grant agreement No. 777377) for the project
LITMUS- and for the project ""REVEAL""; Fondazione IRCCS Ca' Granda ""Ricerca
corrente"", Fondazione Sviluppo Ca' Granda ""Liver-BIBLE"" (PR-0391), Fondazione
IRCCS Ca' Granda ""5permille"" ""COVID-19 Biobank"" (RC100017A). Andrea Biondi
was supported by the grant from Fondazione Cariplo to Fondazione Tettamanti: "Biobanking of Covid-19 patient samples to support national and international research
(Covid-Bank). This research was partly funded by a MIUR grant to the Department of
Medical Sciences, under the program "Dipartimenti di Eccellenza 2018â2022". This
study makes use of data generated by the GCAT-Genomes for Life. Cohort study of
the Genomes of Catalonia, FundaciĂł IGTP. IGTP is part of the CERCA Program /
Generalitat de Catalunya. GCAT is supported by AcciĂłn de DinamizaciĂłn del ISCIIIMINECO and the Ministry of Health of the Generalitat of Catalunya (ADE 10/00026);
the AgĂšncia de GestiĂł dâAjuts Universitaris i de Recerca (AGAUR) (2017-SGR 529).
Marta Marquié received research funding from ant PI19/00335 Acción Estratégica en
Salud, integrated in the Spanish National RDI Plan and financed by ISCIIISubdirecciĂłn General de EvaluaciĂłn and the Fondo Europeo de Desarrollo Regional
(FEDER-Una manera de hacer Europa").Beatriz Cortes is supported by national
grants PI18/01512. Xavier Farre is supported by VEIS project (001-P-001647) (cofunded by European Regional Development Fund (ERDF), âA way to build Europeâ).
Additional data included in this study was obtained in part by the COVICAT Study
Group (Cohort Covid de Catalunya) supported by IsGlobal and IGTP, EIT COVID-19
Rapid Response activity 73A and SR20-01024 La Caixa Foundation. Antonio JuliĂ
and Sara Marsal were supported by the Spanish Ministry of Economy and
Competitiveness (grant numbers: PSE-010000-2006-6 and IPT-010000-2010-36).
Antonio JuliĂ was also supported the by national grant PI17/00019 from the AcciĂłn
Estratégica en Salud (ISCIII) and the FEDER. The Basque Biobank is a hospitalrelated platform that also involves all Osakidetza health centres, the Basque government's Department of Health and Onkologikoa, is operated by the Basque
Foundation for Health Innovation and Research-BIOEF. Mario CĂĄceres received
Grants BFU2016-77244-R and PID2019-107836RB-I00 funded by the Agencia Estatal
de InvestigaciĂłn (AEI, Spain) and the European Regional Development Fund
(FEDER, EU). Manuel Romero GĂłmez, Javier Ampuero Herrojo, RocĂo Gallego DurĂĄn
and Douglas Maya Miles are supported by the âSpanish Ministry of Economy,
Innovation and Competition, the Instituto de Salud Carlos IIIâ (PI19/01404,
PI16/01842, PI19/00589, PI17/00535 and GLD19/00100), and by the Andalussian
government (Proyectos Estratégicos-Fondos Feder PE-0451-2018, COVID-Premed,
COVID GWAs). The position held by Itziar de Rojas Salarich is funded by grant
FI20/00215, PFIS Contratos Predoctorales de FormaciĂłn en InvestigaciĂłn en Salud.
Enrique CalderĂłn's team is supported by CIBER of Epidemiology and Public Health
(CIBERESP), "Instituto de Salud Carlos III". Jan Cato Holter reports grants from
Research Council of Norway grant no 312780 during the conduct of the study. Dr.
SolligÄrd: reports grants from Research Council of Norway grant no 312769. The
BioMaterialBank Nord is supported by the German Center for Lung Research (DZL),
Airway Research Center North (ARCN). The BioMaterialBank Nord is member of
popgen 2.0 network (P2N). Philipp Koehler has received non-financial scientific grants
from Miltenyi Biotec GmbH, Bergisch Gladbach, Germany, and the Cologne
Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases,
University of Cologne, Cologne, Germany. He is supported by the German Federal
Ministry of Education and Research (BMBF).Oliver A. Cornely is supported by the
German Federal Ministry of Research and Education and is funded by the Deutsche
Forschungsgemeinschaft (DFG, German Research Foundation) under Germany's
Excellence Strategy â CECAD, EXC 2030 â 390661388. The COMRI cohort is funded
by Technical University of Munich, Munich, Germany. Genotyping was performed by
the Genotyping laboratory of Institute for Molecular Medicine Finland FIMM
Technology Centre, University of Helsinki. This work was supported by grants of the
Rolf M. Schwiete Stiftung, the Saarland University, BMBF and The States of Saarland
and Lower Saxony. Kerstin U. Ludwig is supported by the German Research
Foundation (DFG, LU-1944/3-1). Genotyping for the BoSCO study is funded by the
Institute of Human Genetics, University Hospital Bonn. Frank Hanses was supported
by the Bavarian State Ministry for Science and Arts. Part of the genotyping was
supported by a grant to Alfredo Ramirez from the German Federal Ministry of Education and Research (BMBF, grant: 01ED1619A, European Alzheimer DNA
BioBank, EADB) within the context of the EU Joint Programme â Neurodegenerative
Disease Research (JPND). Additional funding was derived from the German Research
Foundation (DFG) grant: RA 1971/6-1 to Alfredo Ramirez. Philip Rosenstiel is
supported by the DFG (CCGA Sequencing Centre and DFG ExC2167 PMI and by SH
state funds for COVID19 research). Florian Tran is supported by the Clinician Scientist
Program of the Deutsche Forschungsgemeinschaft Cluster of Excellence âPrecision
Medicine in Chronic Inflammationâ (EXC2167). Christoph Lange and Jan Heyckendorf
are supported by the German Center for Infection Research (DZIF). Thorsen Brenner,
Marc M Berger, Oliver Witzke und Anke Hinney are supported by the Stiftung
UniversitÀtsmedizin Essen. Marialbert Acosta-Herrera was supported by Juan de la
Cierva Incorporacion program, grant IJC2018-035131-I funded by
MCIN/AEI/10.13039/501100011033. Eva C Schulte is supported by the Deutsche
Forschungsgemeinschaft (DFG; SCHU 2419/2-1).N
PercepciĂłn de la educaciĂłn personalizada en una instituciĂłn educativa privada de Lima Metropolitana, 2019
TesisLima NorteEscuela Académico Profesional de Educación PrimariaAtención Integral del infante, niño y adolescenteEl objetivo general del trabajo de investigación fue conocer las percepciones de la educación
personalizada en los estudiantes, padres de familia y docentes, para lo cual estĂĄ basado en
enfoque cualitativo, diseño narrativo, utilizåndose como muestra de seis estudiantes, seis
padres de familias y seis docentes de la ciudad de Lima, PerĂș, con la finalidad de conocer
los resultados y alcances de la aplicaciĂłn de la educaciĂłn personalizada como metodologĂa
de enseñanza. En el presente trabajo de investigación se utilizó instrumentos como la
entrevista y cuestionarios, con el resultado general que la educaciĂłn personalizada interviene
en el desarrollo personal del alumno de manera positiva, a través de educación integral en
valores que es realizada mediante un acompañamiento de la preceptora, a través del trabajo
en equipo con los padres de familia; la conclusiĂłn general del trabajo de investigaciĂłn fue
que la educaciĂłn personalizada es una educaciĂłn integral centrada en las particularidades de
cada estudiante y se evidencia a travĂ©s de la preceptorĂa comentada por los padres de
familias, estudiantes y docentes; ademĂĄs se recomienda realizar mĂĄs investigaciones con
enfoque cuantitativo o cualitativo sobre la aplicaciĂłn de la educaciĂłn personalizada y sus
efectos en el aprendizaje de los estudiantes, ya que actualmente existen escazas
investigaciones, libros, revistas o entrevistas actualizadas respecto al presente tema
Novel genes and sex differences in COVID-19 severity.
Here we describe the results of a genome-wide study conducted in 11â939 COVID-19 positive cases with an extensive clinical information that were recruited from 34 hospitals across Spain (SCOURGE consortium). In sex-disaggregated genome-wide association studies for COVID-19 hospitalization, genome-wide significance (pâ<â5x10-8) was crossed for variants in 3p21.31 and 21q22.11 loci only among males (pâ=Â 1.3x10-22 and pâ=Â 8.1x10-12, respectively), and for variants in 9q21.32 near TLE1 only among females (pâ=Â 4.4x10-8). In a second phase, results were combined with an independent Spanish cohort (1598 COVID-19 cases and 1068 population controls), revealing in the overall analysis two novel risk loci in 9p13.3 and 19q13.12, with fine-mapping prioritized variants functionally associated with AQP3 (pâ=Â 2.7x10-8) and ARHGAP33 (pâ=Â 1.3x10-8), respectively. The meta-analysis of both phases with four European studies stratified by sex from the Host Genetics Initiative confirmed the association of the 3p21.31 and 21q22.11 loci predominantly in males and replicated a recently reported variant in 11p13 (ELF5, pâ=â4.1x10-8). Six of the COVID-19 HGI discovered loci were replicated and an HGI-based genetic risk score predicted the severity strata in SCOURGE. We also found more SNP-heritability and larger heritability differences by age (<60 orââ„â60Â years) among males than among females. Parallel genome-wide screening of inbreeding depression in SCOURGE also showed an effect of homozygosity in COVID-19 hospitalization and severity and this effect was stronger among older males. In summary, new candidate genes for COVID-19 severity and evidence supporting genetic disparities among sexes are provided
Charged-particle multiplicity fluctuations in PbâPb collisions at âsNN = 2.76 TeV
Measurements of event-by-event fluctuations of charged-particle multiplicities in PbâPb collisions at sNNââââ = 2.76 TeV using the ALICE detector at the CERN Large Hadron Collider (LHC) are presented in the pseudorapidity range |η|<0.8 and transverse momentum 0.2<pT<2.0 GeV/c. The amplitude of the fluctuations is expressed in terms of the variance normalized by the mean of the multiplicity distribution. The η and pT dependences of the fluctuations and their evolution with respect to collision centrality are investigated. The multiplicity fluctuations tend to decrease from peripheral to central collisions. The results are compared to those obtained from HIJING and AMPT Monte Carlo event generators as well as to experimental data at lower collision energies. Additionally, the measured multiplicity fluctuations are discussed in the context of the isothermal compressibility of the high-density strongly-interacting system formed in central PbâPb collisions
Measurement of dielectron production in central PbâPb collisions at âsNN = 2.76 TeV
The first measurement of dielectron (e+eâ) production in central (0â10%) Pb-Pb collisions at sNNââââ = 2.76 TeV at the LHC is presented. The dielectron invariant-mass spectrum is compared to the expected contributions from hadron decays in the invariant-mass range 0<mee<3.5 GeV/c2. The ratio of data and the cocktail of hadronic contributions without vacuum Ï0 is measured in the invariant-mass range 0.15<mee<0.7 GeV/c2, where an excess of dielectrons is observed in other experiments, and its value is 1.40±0.28 (stat.)±0.08 (syst.)±0.27 (cocktail). The dielectron spectrum measured in the invariant mass range 0<mee<1 GeV/c2 is consistent with the predictions from two theoretical model calculations that include thermal dielectron production from both partonic and hadronic phases with in-medium broadened Ï0 meson. The fraction of direct virtual photons over inclusive virtual photons is extracted for dielectron pairs with invariant mass 0.1<mee<0.3 GeV/c2, and in the transverse-momentum intervals 1<pT,ee<2 GeV/c and 2<pT,ee<4 GeV/c. The measured fraction of virtual direct photons is consistent with the measurement of real direct photons by ALICE and with the expectations from previous dielectron measurements at RHIC within the experimental uncertainties
Î+c production in pp collisions at âs = 7 TeV and in pâPb collisions at âsNN = 5.02 TeV
The pT-differential production cross section of prompt Î+c charmed baryons was measured with the ALICE detector at the Large Hadron Collider (LHC) in pp collisions at sâ=7 TeV and in p-Pb collisions at sNNââââ=5.02 TeV at midrapidity. The Î+c and ÎÂŻÂŻÂŻÂŻâc were reconstructed in the hadronic decay modes Î+câpKâÏ+, Î+câpK0S and in the semileptonic channel Î+câe+ÎœeÎ (and charge conjugates). The measured values of the Î+c/D0 ratio, which is sensitive to the c-quark hadronisation mechanism, and in particular to the production of baryons, are presented and are larger than those measured previously in different colliding systems, centre-of-mass energies, rapidity and pT intervals, where the Î+c production process may differ. The results are compared with the expectations obtained from perturbative Quantum Chromodynamics calculations and Monte Carlo event generators. Neither perturbative QCD calculations nor Monte Carlo models reproduce the data, indicating that the fragmentation of heavy-flavour baryons is not well understood. The first measurement at the LHC of the Î+c nuclear modification factor, RpPb, is also presented. The RpPb is found to be consistent with unity and with that of D mesons within the uncertainties, and consistent with a theoretical calculation that includes cold nuclear matter effects and a calculation that includes charm quark interactions with a deconfined medium
Neutral pion and η meson production at mid-rapidity in PbâPb collisions at âsNN = 2.76 TeV
Neutral pion and η meson production in the transverse momentum range 1 < pT < 20 GeV/c have been measured at mid-rapidity by the ALICE experiment at the Large Hadron Collider (LHC) in central and semi-central Pb-Pb collisions at sNNâââââ = 2.76 TeV. These results were obtained using the photon conversion method as well as the PHOS and EMCal detectors. The results extend the upper pT reach of the previous ALICE Ï0 measurements from 12 GeV/c to 20 GeV/c and present the first measurement of η meson production in heavy-ion collisions at the LHC. The η/Ï0 ratio is similar for the two centralities and reaches at high pT a plateau value of 0.457 ± 0.013stat ± 0.018syst. A suppression of similar magnitude for Ï0 and η meson production is observed in Pb-Pb collisions with respect to their production in pp collisions scaled by the number of binary nucleon-nucleon collisions. We discuss the results in terms of NLO pQCD predictions and hydrodynamic models. The measurements show a stronger suppression with respect to what was observed at lower center-of-mass energies in the pT range 6 < pT < 10 GeV/c. At pT < 3 GeV/c, hadronization models describe the Ï0 results while for the η some tension is observed