Hydrotherapie in der Psychiatrie des 19. Jahrhunderts

Im 19. Jahrhundert ändern sich die Forschungsansätze in der Physiologie, einer der Leitwissenschaften der Medizin. Diese Änderung hat Folgen für die Erkenntnisgewinnung der gesamten akademische Lehrmedizin. Disziplinen die teilhaben wollten an der Anerkennung der offiziellen Lehrmedizin, mussten sich der Herausforderung einer "physikalisierten" Erkenntnisgewinnung stellen. Die sich im 19. Jahrhuinder etablierende Psychiatrie und die seit der Antike bekannte Wasserheilkunde bilden hier keine Ausnahme. Die Psychiatrie des 19. Jahrhunderts bedient sich dabei ausgiebig der Behandlungsmöglichkeiten die die Wasserheilkunde bietet. Die Untersuchung des Konnexes beider Fachrichtungen vor dem Hintegurnd der wissenschaftsimmanenten Veränderungen in der Medizin des 19. Jahrhunderts, ist das Ziel der vorliegenden Arbeit

The missourische Gnadenwahllehre und ihre Befenntniswidrigfeit

The Missouri Synod\u27s grace and election doctrine statement.https://scholar.csl.edu/digitized_pamphlets/1010/thumbnail.jp

Computing a rectilinear shortest path amid splinegons in plane

We reduce the problem of computing a rectilinear shortest path between two given points s and t in the splinegonal domain \calS to the problem of computing a rectilinear shortest path between two points in the polygonal domain. As part of this, we define a polygonal domain \calP from \calS and transform a rectilinear shortest path computed in \calP to a path between s and t amid splinegon obstacles in \calS. When \calS comprises of h pairwise disjoint splinegons with a total of n vertices, excluding the time to compute a rectilinear shortest path amid polygons in \calP, our reduction algorithm takes O(n + h \lg{n}) time. For the special case of \calS comprising of concave-in splinegons, we have devised another algorithm in which the reduction procedure does not rely on the structures used in the algorithm to compute a rectilinear shortest path in polygonal domain. As part of these, we have characterized few of the properties of rectilinear shortest paths amid splinegons which could be of independent interest

Evidence of effectiveness of herbal medicinal products in the treatment of arthritis

Herbal medicinal products (HMPs) that interact with the mediators of inflammation are used in the treatment of rheumatoid arthritis (RA). The aim of this study was to update a previous systematic review published in 2000. We searched electronic databases (MEDLINE, EMBASE, CISCOM, AMED, CINAHL, Cochrane registers) to June 2007, unrestricted by date or language, and included randomized controlled trials that compared HMPs with inert (placebo) or active controls in patients with rheumatoid arthritis. Five reviewers contributed to data extraction. Disagreements were discussed and resolved by consensus with reference to Cochrane guidelines and advice from the Cochrane Collaboration. Twenty studies (10 identified for this review update, and 10 of the 11 studies of the original review) investigating 14 HMPs were included. Meta-analysis was restricted to data from previous seven studies with oils from borage, blackcurrant and evening primrose containing gamma linolenic acid (GLA). GLA doses equal or higher than 1400 mg/day showed benefit in the alleviation of rheumatic complaints whereas lower doses (∼500 mg) were ineffective. Three studies compared products from Tripterygium wilfordii (thunder god vine) to placebos and returned favorable results but data could not be pooled because the interventions and measures differed. Serious adverse effects occurred in one study. In a follow-up study all side effects were mild to moderate and resolved after the intervention ceased, but time to resolution was variable. Two studies comparing Phytodolor N R to placebo were of limited use because some measures were poorly defined. The remaining studies, each considering differing HMPs, were assessed individually. For most HMPs used in the treatment of RA, the evidence of effectiveness was insufficient to either recommend or discourage their use. Interventions with HMPs containing GLA or Tripterygium wilfordii extract appear to produce therapeutic effects but further investigations are warranted to prove their effectiveness and safety. Copyright © 2009 John Wiley & Sons, Ltd.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/64567/1/3006_ftp.pd

Glial cell type-specific changes in spinal dipeptidyl peptidase 4 expression and effects of its inhibitors in inflammatory and neuropatic pain

Altered pain sensations such as hyperalgesia and allodynia are characteristic features of various pain states, and remain difficult to treat. We have shown previously that spinal application of dipeptidyl peptidase 4 (DPP4) inhibitors induces strong antihyperalgesic effect during inflammatory pain. In this study we observed low level of DPP4 mRNA in the rat spinal dorsal horn in physiological conditions, which did not change significantly either in carrageenan-induced inflammatory or partial nerve ligation-generated neuropathic states. In naive animals, microglia and astrocytes expressed DPP4 protein with one and two orders of magnitude higher than neurons, respectively. DPP4 significantly increased in astrocytes during inflammation and in microglia in neuropathy. Intrathecal application of two DPP4 inhibitors tripeptide isoleucin-prolin-isoleucin (IPI) and the antidiabetic drug vildagliptin resulted in robust opioid-dependent antihyperalgesic effect during inflammation, and milder but significant opioid-independent antihyperalgesic action in the neuropathic model. The opioid-mediated antihyperalgesic effect of IPI was exclusively related to mu-opioid receptors, while vildagliptin affected mainly delta-receptor activity, although mu- and kappa-receptors were also involved. None of the inhibitors influenced allodynia. Our results suggest pathology and glia-type specific changes of DPP4 activity in the spinal cord, which contribute to the development and maintenance of hyperalgesia and interact with endogenous opioid systems

Die lutherische Zionsgemeinde Steinbach-Hallenberg : ihre Gründung und ihr erstes Lebensjahr, in kurzen Zügen dargestellt

Layoutgetreues Digitalisat der Ausg.: Gotha : Selbstverl., 1875 Standort: Universität Marburg, Zentralbibliothek (000) Signatur: VIII C 946 na Bemerkungen: In Fraktur (Hassiaca

Die lutherische Zions-Gemeinde Steinbach-Hallenberg : ihre Vorgeschichte und Gründung, ihre Leiden und Freuden bis zu ihrem 25jährigen Jubiläum ; auf Grund vorhandener Akten und eigener Erfahrung berichtet

Layoutgetreues Digitalisat der Ausg.: Steinbach-Hallenberg : Saft., 1903 Standort: Universität Marburg, Zentralbibliothek (000) Signatur: VIII C 946 nb Bemerkungen: In Fraktur (Hassiaca

Contract seed list for fall delivery 1905 /

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