Criterios de implementación ISO 22000:2018 / ISO 9001:2015 Caso Estudio Sector Lácteo

Todos diagramas y tablas Elaboración PropiaLos inicios de la manufactura de quesos en Colombia se remontan a la época en que los españoles transmiten sus técnicas a los indígenas, mientras ellos conquistaban las diferentes regiones del país. El queso fresco fue el queso que se empezó a fabricar en esa época, puesto que no había que esperar mucho tiempo para su consumo. Este tipo de queso posee una vida útil muy corta. (Melendrez,2013) En Colombia el consumo de quesos frescos tiende a incrementarse, puesto que hoy en día hay mayor conocimiento en los diferentes tipos de quesos y los consumidores han abierto de forma favorable la curiosidad por aprender a degustarlos. A mediados de Febrero de 2019 el consumo de queso en Colombia alcanzó los 1.5 kilos por persona permitiendo de esta manera un desarrollo para la industria. (Portafolio, 2019). En esta ocasión nos centraremos en la producción y comercialización del queso Mozzarella, teniendo en cuenta las Buenas Prácticas de Manufactura (BPM) y la firme intención que tiene la empresa Quesadran en implementar el Sistema de Gestión en Inocuidad Alimentaria (SGIA) , con el fin de mejorar la calidad de sus procesos, para entregar un producto que cumpla con los estándares de calidad y comercialización. El queso mozzarella al ser un queso fresco, con una consistencia semiduro, posee una elasticidad lo cual lo hace muy apetecible en la cocina por su capacidad de gratinado para las diferentes recetas como en el caso de la pizza. Adicional a lo anterior es de resaltar su aporte nutricional como una excelente fuente de proteína, calcio y magnesio.The beginnings of the manufacture of cheeses in Colombia go back to the time when the Spanish transmitted their techniques to the natives, while they conquered the different regions of the country. The fresh cheese was the cheese that began to be manufactured at that time, since you did not have to wait long for its consumption. This type of cheese has a very short shelf life. (Melendrez, 2013) In Colombia the consumption of fresh cheeses tends to increase, since nowadays there is more knowledge about the different types of cheeses and consumers have favorably opened the curiosity to learn how to taste them. In mid-February 2019, cheese consumption in Colombia reached 1.5 kilos per person, thus allowing development for the industry. (Portfolio, 2019). On this occasion we will focus on the production and marketing of Mozzarella cheese, taking into account Good Manufacturing Practices (GMP) and the firm intention of the Quesadran company to implement the Food Safety Management System (SGIA), in order to to improve the quality of its processes, to deliver a product that meets quality and marketing standards. Mozzarella cheese, being a fresh cheese, with a semi-hard consistency, has an elasticity which makes it very palatable in the kitchen due to its gratin capacity for different recipes, such as pizza. In addition to the above, it is worth highlighting its nutritional contribution as an excellent source of protein, calcium and magnesium. (Licata, s.f

Enhancing employability skills of biology graduates through an Interdisciplinary Project-Based Service Learning experience with engineering and translation undergraduate students

We describe an interdisciplinary experience based on the application of the Project-Based Service Learning (PBSL) methodology for six learning outcomes directly related to employability skills. The objective was to assess students’ learning outcomes, the level of satisfaction of students and lecturers with the PBSL, and the advantages and disadvantages of the implementation of this learning methodology. Interdisciplinary teamwork of undergraduate science, engineering, and humanities students was required to design real-world projects to develop their transferable skills, through the process of learning by doing. Students perceived that PBSL favored employability skills such as knowledge acquisition, self-directed learning, problem-solving, critical thinking, communication, and teamwork skills. Students and lecturers showed high satisfaction with PBSL and outlined its advantages as an active and experiential learning methodology. In conclusion, the implementation of the collaborative and interdisciplinary PBSL methodology is decidedly recommended to enhance Biology, Engineering, and Translation graduates’ learning satisfaction and their future employability.Agencia Estatal de Investigación | Ref. EDU2017-82629-RUniversidade de Vigo | Ref. RED-I

Evaluation of a Planar Reconfigurable Phased Array Antenna Driven by a Multi-Channel Beamforming Module at Ka Band

© 2021 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other worksIn this paper, a planar active phased array antenna demonstration with linear polarization (LP) at Ka Band (28-30 GHz) is presented. The proof of concept is carried out to evaluate the possible problems that may arise, to analyze possible calibration stages and to assess the viability of the integration of an active system with a Multi-Channel Beamforming Module (MCBM). To fulfill this task an 8times 8-element planar array arranged in column subarrays of 1times 8 elements for 1D beam steering is proposed. The single element consists of a printed circular patch connected to a microstrip feeding line through metallic vias in a multilayered structure. Both the amplitude and phase distributions are performed by a commercial integrated circuit (IC) designed for transmission purposes, from the common port to each of the 8 output ports. Thus, an evaluation of the IC performance is also included within this work. Despite the inherent amplitude and phase feeding errors of the IC, the beam-steering accuracy of the system is reasonable. A nice correspondence between the simulated and measured 8times 8-element array beam steering directions is obtained, with errors below 1° in the steering of the beamThis work was supported in part by the Spanish Government, Ministry of Economy, National Program of Research, Development and Innovation through the Project FUTURE RADIO ’’Radio systems and technologies for high capacity terrestrial and satellite communications in an hyperconnected world’’ under Grant TEC2017-85529-C3-1-R, and in part by the Project JETSTREAM ’’Desarrollo de una antena banda KA embarcada para la prestación de servicios de acceso a Internet por satélite en aviación comercial’’ in collaboration with TELNET Redes Inteligentes S.A. under Grant RTC-2015-3495-

SHARDS: A global view of the star formation activity at z~0.84 and z~1.23

In this paper, we present a comprehensive analysis of star-forming galaxies (SFGs) at intermediate redshifts (z~1). We combine the ultra-deep optical spectro-photometric data from the Survey for High-z Absorption Red and Dead Sources (SHARDS) with deep UV-to-FIR observations in the GOODS-N field. Exploiting two of the 25 SHARDS medium-band filters, F687W17 and F823W17, we select [OII] emission line galaxies at z~0.84 and z~1.23 and characterize their physical properties. Their rest-frame equivalent widths (EW$_{\mathrm{rf}}$([OII])), line fluxes, luminosities, star formation rates (SFRs) and dust attenuation properties are investigated. The evolution of the EW$_{\mathrm{rf}}$([OII]) closely follows the SFR density evolution of the universe, with a trend of EW$_{\mathrm{rf}}$([OII])$\propto$(1+z)$^3$ up to redshift z~1, followed by a possible flattening. The SF properties of the galaxies selected on the basis of their [OII] emission are compared with complementary samples of SFGs selected by their MIR and FIR emission, and also with a general mass-selected sample of galaxies at the same redshifts. We demonstrate observationally that the UVJ diagram (or, similarly, a cut in the specific SFR) is only partially able to distinguish the quiescent galaxies from the SFGs. The SFR-M$_*$ relation is investigated for the different samples, yelding a logarithmic slope ~1, in good agreement with previous results. The dust attenuations derived from different SFR indicators (UV(1600), UV(2800), [OII], IR) are compared and show clear trends with respect to both the stellar mass and total SFR, with more massive and highly star-forming galaxies being affected by stronger dust attenuation.Comment: Replaced to match the accepted version (24 pages, 1 table, 17 figures). Published in ApJ, 812, 155 (2015): http://stacks.iop.org/0004-637X/812/15

Actualidad de las Plantas Medicinales en Terapéutica

RESUMENLas plantas medicinales han sido utilizadas por el hombre desde tiempo inmemorial para el alivio o curación de sus enfermedades. En la actualidad no solo se utilizan como punto de partida para la obtención de medicamentos industriales sino que mantienen plena vigencia para el tratamiento de numerosas dolencias. A pesar de su origen natural no están exentas de riesgos para la salud pues algunas provocan reacciones adversas e interacciones con otros fármacos que hay que tener en cuenta.En el presente trabajo se repasan las principales plantas medicinales, de gran utilidad terapéutica y amplio uso, clasificadas de acuerdo con los sistemas funcionales sobre los que actúan.Palabras claveFitoterapia, medicamentos, acción farmacológica, principios activos, interacciones medicamento-planta medicinal. ABSTRACTMedicinal plants have been used for the relief or cure of several diseases for centuries. Most of the medicines we used today are derived straight from plants and medicinal plants are used as a drug themselves, with great utility in therapeutics. Despite their natural origin, herbal drugs are not free of side effects or interactions with other drugs that must be taken into account.This study review the efficacy and safety of the most used medicinal plants classified according to the functional systems where they act.Key words:Phytotherapy, medicines, pharmacological action, active principles, interactions drug-medicinal plant

Actividad física, ejercicio y deporte en la lucha contra la obesidad infantil y juvenil

El propósito del presente documento es proponer desde el grupo de expertos en ejercicio físico y salud de EXERNET (Red Española de Investigación en Ejercicio Físico y Salud) una serie de recomendaciones sobre la práctica de la actividad física y deportiva que a nivel individual, familiar e institucional ayuden a prevenir y tratar la obesidad infantil y juvenil, basadas en la evidencia científi ca actual

The Raman Laser Spectrometer for the ExoMars Rover Mission to Mars

The Raman Laser Spectrometer (RLS) on board the ESA/Roscosmos ExoMars 2020 mission will provide precise identification of the mineral phases and the possibility to detect organics on the Red Planet. The RLS will work on the powdered samples prepared inside the Pasteur analytical suite and collected on the surface and subsurface by a drill system. Raman spectroscopy is a well-known analytical technique based on the inelastic scattering by matter of incident monochromatic light (the Raman effect) that has many applications in laboratory and industry, yet to be used in space applications. Raman spectrometers will be included in two Mars rovers scheduled to be launched in 2020. The Raman instrument for ExoMars 2020 consists of three main units: (1) a transmission spectrograph coupled to a CCD detector; (2) an electronics box, including the excitation laser that controls the instrument functions; and (3) an optical head with an autofocus mechanism illuminating and collecting the scattered light from the spot under investigation. The optical head is connected to the excitation laser and the spectrometer by optical fibers. The instrument also has two targets positioned inside the rover analytical laboratory for onboard Raman spectral calibration. The aim of this article was to present a detailed description of the RLS instrument, including its operation on Mars. To verify RLS operation before launch and to prepare science scenarios for the mission, a simulator of the sample analysis chain has been developed by the team. The results obtained are also discussed. Finally, the potential of the Raman instrument for use in field conditions is addressed. By using a ruggedized prototype, also developed by our team, a wide range of terrestrial analog sites across the world have been studied. These investigations allowed preparing a large collection of real, in situ spectra of samples from different geological processes and periods of Earth evolution. On this basis, we are working to develop models for interpreting analog processes on Mars during the mission. Key Words: Raman spectroscopy—ExoMars mission—Instruments and techniques—Planetary sciences—Mars mineralogy and geochemistry—Search for life on Mars. Astrobiology 17, 627–65

Experiencias en la tutorización de enseñanzas técnicas

El PAT en la Escuela Politécnica está abierto a todos aquellos tutores que deseen formar parte del plan y también a todos los alumnos, que, voluntariamente pueden marcar la opción de participar en el plan en la matrícula, y también a aquellos que, a pesar de no marcar la opción en la matrícula, finalmente han decidido seguir el plan de acción tutorial. Esta característica de participación e inscripción voluntaria permite que el trabajo se realice más satisfactoriamente tanto por parte de tutores como por parte de los alumnos, puesto que han decidido seguir el plan por ello mismos y no como una imposición. Con este trabajo nos proponemos presentar nuestras experiencias en el desarrollo de la tutorización de nuestros estudiantes así como la evolución en el desarrollo de la tutorización por pares

Coordinación del Plan de Acción Tutorial en la Escuela Politécnica Superior

Al igual que en cursos anteriores en la Escuela Politécnica se desarrolla, promovido por el Vicerrectorado de Estudios, Formación y Calidad, coordinado desde el Instituto de Ciencias de la Educación, el Plan de Acción Tutorial (PAT) el cual está abierto a todos aquellos tutores que deseen formar parte del plan y también a todos los estudiantes, que, voluntariamente pueden marcar la opción de participar en el plan en la matrícula, y también a aquellos que, a pesar de no marcar la opción en la matrícula, finalmente han decidido seguir el plan de acción tutorial. Esta característica de participación e inscripción voluntaria permite que el trabajo se realice más satisfactoriamente tanto por parte de tutores como por parte de los estudiantes, puesto que han decidido seguir el plan por ello mismos y no como una imposición. Con este resumen nos proponemos presentar nuestras experiencias en el desarrollo del PAT de nuestro centro

Expression of CD20 after viral reactivation renders HIV-reservoir cells susceptible to Rituximab

Rituximab; Viral reactivation; CD20Rituximab; Reactivació viral; CD20Rituximab; Reactivación viral; CD20The identification of exclusive markers to target HIV-reservoir cells will represent a significant advance in the search for therapies to cure HIV. Here, we identify the B lymphocyte antigen CD20 as a marker for HIV-infected cells in vitro and in vivo. The CD20 molecule is dimly expressed in a subpopulation of CD4-positive (CD4+) T lymphocytes from blood, with high levels of cell activation and heterogeneous memory phenotypes. In lymph node samples from infected patients, CD20 is present in productively HIV-infected cells, and ex vivo viral infection selectively upregulates the expression of CD20 during early infection. In samples from patients on antiretroviral therapy (ART) this subpopulation is significantly enriched in HIV transcripts, and the anti-CD20 monoclonal antibody Rituximab induces cell killing, which reduces the pool of HIV-expressing cells when combined with latency reversal agents. We provide a tool for targeting this active HIV-reservoir after viral reactivation in patients while on ART.This study was supported by the American National Institutes of Health (grant R21AI118411 to M.B.), the Spanish Secretariat of Science and Innovation and FEDER funds (grant SAF2015-67334-R [MINECO/FEDER]), the Spanish "Ministerio de Economia y Competitividad, Instituto de Salud Carlos III" (ISCIII, PI17/01470), GeSIDA and the Spanish AIDS network Red Tematica Cooperativa de Investigacion en SIDA (RD16/0025/0007). M.B. is supported by the Miguel Servet program funded by the Spanish Health Institute Carlos III (CP17/00179). M.G. is supported by the "Pla estrategic de recerca i innovacio en salut" (PERIS), from the Catalan Government