La relación del teletrabajo en la productividad de los colaboradores en una empresa retail de electrodomésticos

Integra Retail empresa que pertenece al rubro de venta al por mayor y menor de electrodomésticos, se encuentra con un problema de baja productividad y alta rotación del personal sobre todo en las áreas de Recursos Humanos y de Auditoría Interna. Ello, luego del cambio de labores de manera remota a regresar a la presencialidad, mediante el presente trabajo se busca identificar si existe una relación entre la productividad de los trabajadores con el “teletrabajo”. Se revisaron diversas investigaciones y teorías que nos aclaren el panorama de la problemática y de las cuales nos podríamos apoyar para brindar diversas soluciones. La primera alternativa es que se regrese a realizar teletrabajo 100%. La segunda alternativa es el trabajo mixto en donde el colaborador tiene la oportunidad de optimizar el tiempo al no tener que realizar desplazamientos hacia el lugar de trabajo, que solo generan fatiga y estrés, y tener un balance entre el trabajo y vida personal; teniendo una mayor efectividad en cada actividad que realiza. La última alternativa es la presencialidad y se contrate más personal para cubrir por completo los procesos; ya que hay actividades que se deben realizar en provincia. Se considera que la mejor alternativa de solución es la implementación del trabajo mixto, con el apoyo de la tecnología de comunicación tan avanzada que actualmente existe. Con ello, el colaborador se encontrará con mayor disposición a cumplir con sus tareas asignadas, tendrá disponibilidad de manejar sus propios horarios según sus responsabilidades y podrá realizarlo desde cualquier ubicación.Integra Retail company that belongs to the wholesale and retail sale of household appliances, is faced with a problem of low productivity and high staff turnover, especially in the areas of Human Resources and Internal Audit. This, after the change from working remotely to return to face-to-face work, this paper seeks to identify whether there is a relationship between the productivity of workers with the "teleworking". We reviewed various research and theories that clarify the picture of the problem and which we could support us to provide various solutions. The first alternative is to return to 100% teleworking. The second alternative is the mixed work where the employee has the opportunity to optimize time by not having to travel to the workplace, which only generate fatigue and stress, and have a balance between work and personal life; having greater effectiveness in each activity performed. The last alternative is to be on-site and hire more personnel to completely cover the processes, since there are activities that must be carried out in the province. It is considered that the best alternative solution is the implementation of mixed work, with the support of the advanced communication technology that currently exists. With this, the collaborator will be more willing to fulfill their assigned tasks, will be able to manage their own schedules according to their responsibilities, and will be able to do it from any location.Trabajo de Suficiencia Profesiona

Mathematical modeling of vertical movement of the upper shaft in cane mills

This study introduces a mathematical model to describe the floating effects of the top roll in sugarcane mills. The model is developed from experimental data measured during the operation of a sugarcane mill. The measured data is fitted using the top shaft rotation period of the mill and dividing on intervals to individually fit each interval obtaining a function defined by parts. The resulting model shows a correlation coefficient of R2 ≥ 0.97. This allow including the floating effect in the study and design of other elements of sugarcane mills

Characterization of oral leukoplakia. Justo Ortelio Pestana Lorenzo Provincial Teaching Stomatology Clinic. 2019

Introducción: la leucoplasia bucal es una lesión premaligna que se manifiestan como una mancha blanca, no suelen ser dolorosas y pueden pasar desapercibidas.Objetivo: caracterizar la leucoplasia bucal en pacientes de la Clínica Estomatológica Docente Provincial “Justo Ortelio Pestana Lorenzo” durante el año 2019Métodos: se realizó un estudio observacional descriptivo transversal de enero a diciembre de 2019 en la clínica estomatológica provincial “Dr. Justo Ortelio Pestana Lorenzo”. Se seleccionaron 21 pacientes portadores de leucoplasiabucal que cumplieron criterios de inclusión. Las variables estudiadas fueron edad, sexo, color de la piel, factores de riesgo y localización de la lesión.Resultados: el 57,1 % de los pacientes con leucoplasia tenían entre 45 y 59 años de edad, el 61,9 % pertenecía al sexo masculino y el 47,6 % de color de la piel blanco. La zona mayormente afectada fue la mucosa del carrillo en el 42,8 %. De los pacientes examinados, el 57,1 % fueron fumadores y el 28,8 % presentó prótesis desajustadas e higiene bucal deficiente.Conclusiones: predominaron los pacientes del grupo entre 45 y 59 años de edad, con sexo masculino y color de la piel blanca, la mayor localización en la mucosa del carrillo y los factores de riesgo hábito de fumar, la deficiente higiene bucal y las prótesis desajustadas.Introduction: oral leukoplakia is a premalignant lesion that usually manifests as a white spot, but it is not usually painful and can go unnoticed.Objective: to characterize oral leukoplakia in patients of the "Justo Ortelio Pestana Lorenzo" Provincial Teaching Stomatology Clinic during 2019.Methods: a cross-sectional descriptive observational study was conducted from January to December 2019 at the "Dr. Justo Ortelio Pestana Lorenzo" Provincial Stomatological Clinic. Twenty-one patients with oral leukoplakia who met inclusion criteria were selected. The variables studied were age, sex, skin color, risk factors and location of the lesion.Results: 57,1 % of the patients with leukoplakia were between 45 and 59 years of age, 61,9 % were male and 47,6 % were of white skin color. 42,8 % of the area most affected was the mucosa of the cheek. Of the patients examined, 57,1 % were smokers and 28,8 % presented maladjusted prosthesis and deficient oral hygiene.Conclusions: patients between 45 and 59 years of age were predominant, with male sex and white skin color, the greatest localization in the mucosa of the cheek and the risk factors were smoking, poor oral hygiene and maladjusted prostheses

Predictors of diabetes risk in urban and rural areas in Colombia

Background: Nutritional habits low in fruits and vegetables and sedentary lifestyle are associated with a higher risk of developing Type 2 Diabetes (T2D). However, it is important to assess differences between urban and rural areas. This study aimed to analyze the associations between the risk of developing T2D and setting in the Colombian north coast in 2017. Methods: This cross-sectional study included 1,005 subjects. Data was collected by interviewing self-identified members of an urban community and a rural-indigenous population. The interaction terms were evaluated as well as the confounders. Then, adjusted binary logistic regressions were used to estimate the odds ratio (OR) and 95% Confidence Intervals (CI). Results: subjects with a high risk of T2D are more likely to belong to the urban setting (OR = 1.908; 95%CI = 1.201-2.01) compared with those with lower T2D after adjusting for age, Body Mass Index (BMI), physical activity, history of high levels of glycemia, and diabetes in relatives. Conclusions: Urban communities are more likely to have T2D compared with rural-indigenous populations. These populations have differences from the cultural context, including personal, and lifestyle factors.Peer reviewe

The Influence of Perceived Parenting on Substance Initiation Among Mexican Children

Parents shape their children\u27s behaviors and impact their developmental trajectories. Despite this, few studies have examined the potential relationship between child reported parenting factors and lifetime substance use and use intentions. The current study examined the potential impact of parenting factors (i.e., positive parenting, supervision, parental illicit substance use, substance-specific communication) on early substance use and intentions among Latinx children. Data for the present study utilized a representative sample of Mexican children (n = 52,171; 5th and 6th grades) who participated in a national survey on substance use. Children reported their demographics, lifetime substance use/intentions, and perceived parenting characteristic and practices. Child reported parental (i.e., individual or both parents) illicit substance use was associated with the largest increases in risk for reporting lifetime use of all substances examined. Higher levels of positive parenting were consistently associated with reductions in risk for reporting intentions for and use of all substances examined. Parent-child substance specific communication was not significantly related to child reported lifetime use or use intentions, with the exception of a minor decrease in the odds of reporting lifetime inhalant use. Supervision was associated with small to modest increase in risk. Substance use prevention efforts targeting Latinx populations may benefit from promoting positive parenting and direct supervision during childhood. Targeted prevention efforts may be needed for Latinx children exposed to parental illicit substance use, as they may be especially at risk for early substance initiation

Conjunctival ultraviolet autofluorescence as a biomarker of outdoor exposure in myopia: a systematic review and meta-analysis

Outdoor exposure is considered the primary modifiable risk factor in preventing the development of myopia. This effect is thought to be attributed to the light-induced synthesis and release of dopamine in the retina. However, until recent years, there was no objective quantifiable method available to measure the association between time spent outdoors and myopia. It is only recently that the conjunctival ultraviolet autofluorescence (CUVAF) area, serving as a biomarker for sun exposure, has begun to be utilized in numerous studies. To provide a comprehensive summary of the relevant evidence pertaining to the association between the CUVAF area and myopia across different geographic regions and age groups, a systematic review and meta-analysis were conducted. The search encompassed multiple databases, including MEDLINE, SCIENCE DIRECT, GOOGLE SCHOLAR, WEB OF SCIENCE, and SCOPUS, and utilized specific search terms such as conjunctival ultraviolet autofluorescence, CUVAF, UVAF, objective marker of ocular sun exposure, myopia, degenerative myopia, and high myopia. The bibliographic research included papers published between the years 2006 and 2022. A total of 4051 records were initially identified, and after duplicates were removed, 49 articles underwent full-text review. Nine articles were included in the systematic review. These studies covered myopia and outdoor exposure across different regions (Australia, Europe and India) with a total population of 3615 individuals. They found that myopes generally had smaller CUVAF areas compared to non-myopes. The meta-analysis confirmed this, revealing statistically smaller CUVAF areas in myopic patients, with a mean difference of - 3.30 mm2 (95% CI - 5.53; - 1.06). Additionally, some studies showed a positive correlation between more outdoor exposure and larger CUVAF areas. In terms of outdoor exposure time, myopic patients reported less time outdoors than non-myopic individuals, with a mean difference of - 3.38 h/week (95% CI - 4.66; - 2.09). Overall, these findings highlight the connection between outdoor exposure, CUVAF area and myopia, with regional variations playing a significant role. The results of this meta-analysis validate CUVAF as a quantitative method to objectively measure outdoor exposure in relation with myopia development

Secretion of biologically active interferon-gamma inducible protein-10 (IP-10) by Lactococcus lactis

<p>Abstract</p> <p>Background</p> <p>Chemokines are a large group of chemotactic cytokines that regulate and direct migration of leukocytes, activate inflammatory responses, and are involved in many other functions including regulation of tumor development. Interferon-gamma inducible-protein-10 (IP-10) is a member of the C-X-C subfamily of the chemokine family of cytokines. IP-10 specifically chemoattracts activated T lymphocytes, monocytes, and NK cells. IP-10 has been described also as a modulator of other antitumor cytokines. These properties make IP-10 a novel therapeutic molecule for the treatment of chronic and infectious diseases. Currently there are no suitable live biological systems to produce and secrete IP-10. <it>Lactococcus lactis </it>has been well-characterized over the years as a safe microorganism to produce heterologous proteins and to be used as a safe, live vaccine to deliver antigens and cytokines of interest. Here we report a recombinant strain of <it>L. lactis </it>genetically modified to produce and secrete biologically active IP-10.</p> <p>Results</p> <p>The IP-10 coding region was isolated from human cDNA and cloned into an <it>L. lactis </it>expression plasmid under the regulation of the pNis promoter. By fusion to the usp45 secretion signal, IP-10 was addressed out of the cell. Western blot analysis demonstrated that recombinant strains of <it>L. lactis </it>secrete IP-10 into the culture medium. Neither degradation nor incomplete forms of IP-10 were detected in the cell or supernatant fractions of <it>L. lactis</it>. In addition, we demonstrated that the NICE (nisin-controlled gene expression) system was able to express IP-10 "de novo" even two hours after nisin removal. This human IP-10 protein secreted by <it>L. lactis </it>was biological active as demonstrated by Chemotaxis assay over human CD3+T lymphocytes.</p> <p>Conclusion</p> <p>Expression and secretion of mature IP-10 was efficiently achieved by <it>L. lactis </it>forming an effective system to produce IP-10. This recombinant IP-10 is biologically active as demonstrated by its ability to chemoattract human CD3+ T lymphocytes. This strain of recombinant <it>L. lactis </it>represents a potentially useful tool to be used as a live vaccine <it>in vivo</it>.</p

Un estudio de las propiedades estructurales, magnéticas y eléctricas de los compuestos Ba1-xNaxCoO3(x = 0.25, 0.5, 0.75)

Los materiales de tipo cobaltita que presentan transición metal-aislante tienen relevancia en el mercado de la electrónica de consumo. En este trabajo presentamos las propiedades estructurales, magnéticas y eléctricas de las cobaltitas Ba1-xNaxCoO3 (con x = 0.25, 0.5, 0.75). Todas las muestras se sintetizaron mediante un proceso de reacción en estado sólido y su estructura cristalina se determinó a partir de datos de difracción de rayos X (DRX), mediante el método de Rietveld, el cual indicó que las muestras cristalizan en el grupo espacial ortorrómbico C2221 (N.o 20). La microestructura de las muestras sinterizadas se caracterizó mediante microscopía electrónica de barrido (MEB). Las medidas de susceptibilidad magnética confirmaron un comportamiento paramagnético para x ≥ 0.5 en el rango de temperatura estudiado y un pico amplio alrededor de 33 K en la muestra x = 0.25, lo cual es característico de los comportamientos antiferromagnéticos. Las medidas de resistividad permitieron determinar el comportamiento aislante de muestras con x = 0.5 y x = 0.75, mientras que a bajo contenido de sodio (x = 0.25), se observó una transición metal-aislante con temperatura de transición cercana a 105 K. 105 K.Cobaltite-like materials having metal-insulator transitions are relevant in the consumer electronics market. In this work, we present the structural, magnetic, and electrical properties of Ba1-xNaxCoO3 (with x = 0.25, 0.5, 0.75) cobaltite. All samples were synthesized using a solid-state reaction process. Their crystal structure was determined using X-ray diffraction (XRD) data by the Rietveld method, which showed that all the samples were crystallized in the orthorhombic space group C2221 (N.° 20). The microstructure of the sintered samples was characterized by scanning electron microscopy (SEM). The magnetic susceptibility measurements confirmed a paramagnetic behavior for x ≥ 0.5 in the temperature range that was used. Likewise, a broad peak around 33 K in the sample x = 0.25, and characteristic of antiferromagnetic behaviors were observed. On the other hand, resistivity contributed to determining the insulating behavior of samples where x = 0.5 and x = 0.75. In contrast, at low sodium content (x = 0.25), a metal-insulator transition was observed with transition temperature near 105 K

miRNA profiling during antigen-dependent T cell activation: A role for miR-132-3p

microRNAs (miRNAs) are tightly regulated during T lymphocyte activation to enable the establishment of precise immune responses. Here, we analyzed the changes of the miRNA profiles of T cells in response to activation by cognate interaction with dendritic cells. We also studied mRNA targets common to miRNAs regulated in T cell activation. pik3r1 gene, which encodes the regulatory subunits of PI3K p50, p55 and p85, was identified as target of miRNAs upregulated after T cell activation. Using 3'UTR luciferase reporter-based and biochemical assays, we showed the inhibitory relationship between miR-132-3p upregulation and expression of the pik3r1 gene. Our results indicate that specific miRNAs whose expression is modulated during T cell activation might regulate PI3K signaling in T cells.We thank Miguel Vicente-Manzanares for help with English editing and Almudena R. Ramiro for helpful discussions. We appreciate help from Gloria Martinez del Hoyo on DCs experiments set up. We also thank the CNIC Genomics, Bioinformatics and Cellomics Units for technical support. This work was supported by grants SAF2014-55579R from Ministerio de Economia y Competitividad-Spain, ERC-2011-AdG 294340-GENTRIS, CIBER CARDIOVASCULAR (FEDER and Instituto de Salud Carlos III), PIE-13-00041 and INDISNET S2011-BMD-2332 (F.S.M.). The Centro Nacional de Investigaciones Cardiovasculares (CNIC, Spain) is supported by the Ministerio de Economia y Competitividad-Spain and the Pro-CNIC Foundation.S