Building a bridge from Early Childhood Education to Primary Education

Este Trabajo de Fin de Grado (TFG) tratará sobre algo tan relevante como es favorecer la atención a la diversidad, desde el modelo de la inclusión y a través de la propuesta de una palanca como es la transición educativa de la Educación Infantil a la Educación Primaria. Cuando no se tiene en cuenta el gran cambio que supone para sus estudiantes y familiares el paso de una etapa a otra, podemos decir que se van construyendo una serie de barreras delante de ellos, con esto, quiero hacer llegar al lector y posibilitar la utilización de unas palancas, es decir, actuaciones o proyectos que faciliten el proceso de la escuela para favorecer la atención a la diversidad de su alumnado y así hacer ese cambio más amable, más delicado y bonito.This Final Degree Project will deal with something as relevant as favoring attention to diversity, from the model of inclusion and through the proposal of a lever such as the educational transition from Early Childhood Education to Primary Education. When the great change that the passage from one stage to another implies for their students and relatives is not taken into account, we can say that a series of barriers are being built in front of them, with this, I want to reach reader and enable the use of some levers, that is, actions or proyects that facilite the process of the school to favor attention to the diversity of its students and thus make that change more friendy, more delicate and beautiful.Grado en Magisterio en Educación Infanti

Relaciones entre el nivel de actividad física, experiencia deportiva e inteligencia emocional en alumnos de Grado de la Comunidad Madrid: estudio de protocolo.

A pesar de la variedad de enfoques ante el constructo de inteligencia emocional y la actividad física, se sigue investigando en esta área focalizando la atención en los deportistas actuales y en su rendimiento y no en las relaciones que estas actividades puedan tener con los diferentes niveles de las dimensiones de la inteligencia emocional. El objetivo principal de la investigación es estudiar las relaciones entre actividad física, experiencia deportiva a lo largo de la vida e inteligencia emocional en los alumnos universitarios. Se contactará con 1301 alumnos de Grado de la Comunidad de Madrid que contestarán a través de Google Forms a las siguientes herramientas: GPAQv2, encuesta ad hoc. de experiencia deportiva y TMMS-24. Se emplearán pruebas descriptivas, se llevará a cabo correlación bivariada de Pearson y se emplearán modelos de regresión múltiple por pasos. Los resultados ayudarán a enmarcar las investigaciones futuras dotando de importancia al deporte y a la actividad física como elementos fundamentales para el desarrollo y entrenamiento de forma transversal de las destrezas emocionales, encontrando y analizando las relaciones que existen entre el nivel de actividad física, la experiencia deportiva a lo largo de la vida de las personas y la inteligencia emocional en alumnos universitarios de Grado de la Comunidad de Madrid. Esta investigación pretende abrir una vía más en la que el deporte y la actividad física, vuelvan a ser el contexto idóneo para la solución de necesidades intrapersonales e interpersonales.post-print136 K

Resilience in Sports: Sport Type, Gender, Age and Sport Level Differences.

There seems to be a broad consensus that there is a positive correlation between resilience and sport performance. However, different studies show divergent results on the role played by certain variables in this relationship. This study aimed to analyze the possible relationships between resilience levels and the practiced sport according to gender, age, and competitive level of the athletes in 1047 competitive athletes from five different sports (handball, basketball, volleyball, athletics, and judo). Resilience was assessed with the Spanish version of the Brief Resilience Scale (BRS). Results of independent samples t-tests or analysis of variance (ANOVA) showed no significant differences on the level of resilience according to the practiced sport or the competitive level. However, the analyses of covariance (ANCOVA) showed that they were related to the gender and age of the athletes, being higher in males than in females, and there was a positive correlation with age. These results seem to suggest the convenience of using differentiated strategies, according to gender and age, when working on all those protective factors that could allow the athlete to perform better when facing adversity in the competitive environmentpost-print384 K

Emotional Intelligence of Undergraduate Athletes: The Role of Sports Experience.

Sport is an emotional experience. Studies have shown that high emotional intelligence (EI) is associated with better sports performance, though different aspects of sports experience and their relationship with EI are still unclear. This study examined the possible relationships between sports experience and EI dimensions of undergraduate athletes. Likewise, according to the differences described in the literature between men and women, the secondary aim was to identify the possible relationship between EI and sports experience in both subgroups. A total of 1784 [712 men (39.9%), 1072 women (60.1%); mean age = 21.3 years, SD = 4.2)] undergraduate athletes completed the Trait Meta Mood Scale and a sports experience questionnaire. Comparisons between groups were performed using Mann–Whitney-U and H-Kruskal–Wallis tests and correlations between variables were analyzed using Spearman correlation. We found that the number of different sports practiced and the number of years practicing sports were positively associated with emotional repair (ER). However, the number of years practicing sports was negatively associated with emotional attention (EA). Male athletes who trained more and had a higher competitive level were more likely to show higher ER. In any case, it is necessary to take into account that all the associations were weak. Our study suggested that athletes tend to attend to and value their feelings and use positive thinking to repair their negative moods.post-print196 K

Shortage of dNTPs underlies altered replication dynamics and DNA breakage in the absence of the APC/C cofactor Cdh1

This research was funded by grants from the Spanish Ministry of Economy and Competitiveness MINECO (CSD2007-0015, BFU2011-28274 and BFU2014-55439) and Junta de Castilla y León (CSI151U13 and CSI084U16), the Swedish Cancer Society, the Knut and Alice Wallenberg Foundation and the Swedish Research Council (A.C.). I.G.H is supported by Fundación Científica de la Asociación Española contra el Cáncer (AECC). J.G. and R.R were recipients of CSIC JAE and FPU predoctoral fellowships (MINECO)Peer reviewedPostprin

Emotional Intelligence in Physical Activity, Sports and Judo: A Global Approach.

Emotional intelligence (EI) has been studied in relation to health and physical activity (PA) or in a sport-specific approach. EI is related to sports performance; however, combat sports seem to show characteristics of their own that involve better control of emotions than other sports. This study aimed to analyse whether there are differences in EI dimensions between those who do not achieve World Health Organization (WHO) PA recommendations, those who meet WHO PA recommendations, those who meet WHO PA recommendations practising sports, and judokas of different levels. A descriptive and cross-sectional study was conducted. The sample comprised 2938 undergraduate students from Madrid and 487 active Spanish judokas. PA was measured by the Global Physical Activity Questionnaire (GPAQ). EI was assessed by the Trait Meta-Mood Scale (TMMS-24). Three different one-way ANOVA and ANCOVA (controlling for gender and age) were conducted to compare the effect of type of group studied on the EI dimensions. Significant differences in EI dimensions were found between those who do not meet PA recommendations, those who meet PA recommendations, those who meet PA recommendations practising sports, and judo athletes of different levels. However, when controlling for gender and age, these differences remained specifically in emotional attention and in emotional repair. Judo athletes and high-performance judo athletes showed better EI than the rest of the studied groups.post-print375 K

Physical Activity and Mental Health in Undergraduate Students

[EN] Most research support positive relationships between physical activity and mental health. However, possible moderating variables of these relationships have also been identified, such as age, gender, level of physical activity, and the scope of physical activity. This study aimed to analyze the relationships between physical activity and mental health levels in undergraduate students, assessing whether these associations can change depending on the level of physical activity (low, medium, or high) and the setting (occupational, commuting, or leisure time physical activity) in which it was performed. A descriptive and cross-sectional study was conducted. The sample comprised 847 undergraduate students. Physical activity and mental health were measured by the Global Physical Activity Questionnaire (GPAQv2) and the General Health Questionnaire (GHQ-12). We found relationships between students’ physical activity level and their mental health status. The higher the total physical activity, the better their mental health scores. High levels of commuting and leisure time physical activity is also associated with better mental health, while only moderate levels of occupational physical activity are associated with better mental health status. Regarding the possible associations between physical activity and vulnerability to mental health problems, with the fully adjusted regression model, leisure time and occupational physical activity remain protective of a poor state of mental health. Leisure time physical activity, performed at a high level, and moderate occupational physical activity seems to be the best combination of physical activity to reduce students’ vulnerability to potential mental health problems.SIUniversidad Francisco de Vitori

USP37 deubiquitinates Cdt1 and contributes to regulate DNA replication

DNA replication control is a key process in maintaining genomic integrity. Monitoring DNA replication initiation is particularly important as it needs to be coordinated with other cellular events and should occur only once per cell cycle. Crucial players in the initiation of DNA replication are the ORC protein complex, marking the origin of replication, and the Cdt1 and Cdc6 proteins, that license these origins to replicate by recruiting the MCM2-7 helicase. To accurately achieve its functions, Cdt1 is tightly regulated. Cdt1 levels are high from metaphase and during G1 and low in S/G2 phases of the cell cycle. This control is achieved, among other processes, by ubiquitination and proteasomal degradation. In an overexpression screen for Cdt1 deubiquitinating enzymes, we isolated USP37, to date the first ubiquitin hydrolase controlling Cdt1. USP37 overexpression stabilizes Cdt1, most likely a phosphorylated form of the protein. In contrast, USP37 knock down destabilizes Cdt1, predominantly during G1 and G1/S phases of the cell cycle. USP37 interacts with Cdt1 and is able to de-ubiquitinate Cdt1 in vivo and, USP37 is able to regulate the loading of MCM complexes onto the chromatin. In addition, downregulation of USP37 reduces DNA replication fork speed. Taken together, here we show that the deubiquitinase USP37 plays an important role in the regulation of DNA replication. Whether this is achieved via Cdt1, a central protein in this process, which we have shown to be stabilized by USP37, or via additional factors, remains to be tested.The authors are grateful to V. Smits for careful reading of the manuscript. This work was supported by grants from the Spanish Ministry of Economy and Competitiveness (SAF2013-49149-R, BFU2014-51672-REDC), Instituto de Salud Carlos III (BA15/00092) and Fundacion CajaCanarias (AP2015/008) to RF.S

PDS5 proteins are required for proper cohesin dynamics and participate in replication fork protection.

Cohesin is a chromatin-bound complex that mediates sister chromatid cohesion and facilitates long-range interactions through DNA looping. How the transcription and replication machineries deal with the presence of cohesin on chromatin remains unclear. The dynamic association of cohesin with chromatin depends on WAPL cohesin release factor (WAPL) and on PDS5 cohesin-associated factor (PDS5), which exists in two versions in vertebrate cells, PDS5A and PDS5B. Using genetic deletion in mouse embryo fibroblasts and a combination of CRISPR-mediated gene editing and RNAi-mediated gene silencing in human cells, here we analyzed the consequences of PDS5 depletion for DNA replication. We found that either PDS5A or PDS5B is sufficient for proper cohesin dynamics and that their simultaneous removal increases cohesin's residence time on chromatin and slows down DNA replication. A similar phenotype was observed in WAPL-depleted cells. Cohesin down-regulation restored normal replication fork rates in PDS5-deficient cells, suggesting that chromatin-bound cohesin hinders the advance of the replisome. We further show that PDS5 proteins are required to recruit WRN helicase-interacting protein 1 (WRNIP1), RAD51 recombinase (RAD51), and BRCA2 DNA repair associated (BRCA2) to stalled forks and that in their absence, nascent DNA strands at unprotected forks are degraded by MRE11 homolog double-strand break repair nuclease (MRE11). These findings indicate that PDS5 proteins participate in replication fork protection and also provide insights into how cohesin and its regulators contribute to the response to replication stress, a common feature of cancer cells.This work was supported by the Spanish Ministry of Economy and Competitiveness and FEDER Grants BFU2013-48481-R and BFU2016-79841-R (to A. L.) and BFU2016-80402-R (to J. M.) and by FPI "Severo Ochoa" fellowships (to C. M. and M. R.-T.). This work was also supported by funding from Boehringer Ingelheim Fonds (to M. R.-T.). The authors declare that they have no conflicts of interest with the contents of this article.S