Participatory design through the CoAnnotation tool in external university internships

Con el objetivo de mejorar la experiencia de la asignatura Prácticas Externas I, del Grado de Pedagogía de la Facultad de Ciencias de la Educación de la Universidad de Sevilla y para cubrir las necesidades sentidas por el profesorado y alumnado, se han llevado a cabo, durante el curso 2020-21, dos propuestas: blog colaborativo y simulaciones-videoconferencia para llevar a cabo un aprendizaje flexible en el aprendizaje de esta asignatura. Tras la creación y publicación de un vídeo en CoAnnotation, los miembros de la RedTicPraxis a través de un diseño participativo realizaron valoraciones de acuerdo con el objetivo planteado. El procedimiento seguido para el análisis de datos recogidos en CoAnnotation ha consistido en un sistema categorial, creado a través de las etiquetas y el software utilizado Atlas.ti versión 8.4. Los resultados demuestran que las categorías más destacadas son Buenas Prácticas, Colaboración y Función. Las dos modalidades, Blog y SimulaciónVideoconferencia, han sido consideradas como buenas prácticas con TIC por el profesorado, estudiantes e instituciones. Estas herramientas les han permitido la recuperación de experiencias debido a la retroalimentación que ofrecen y el fomento de la reflexión sobre sus prácticas y las de sus compañeros/as.With the aim of improving the experience of the course External Internships I, of the Degree in Pedagogy of the Faculty of Education Sciences of the University of Seville and to meet the needs felt by the teaching staff and students, two proposals have been carried out during the 2020-21 academic year: collaborative blog and videoconference simulations to make the flexible learning. After the creation and publication of a video in CoAnnotation, the members of the RedTicPraxis, through a participatory design, carried out evaluations in accordance with the proposed objective. The procedure followed for the analysis of the data collected in CoAnnotation consisted of a categorial system, created using labels and the software Atlas.ti version 8.4. The results show that the most prominent categories are Good Practice, Collaboration and Function. The two modalities, Blog and SimulationVideoconference have been considered as good practices with ICT by teachers, students and institutions. These tools have allowed them to recover experiences due to the feedback they offer and to encourage reflection on their practices and those of their peers

Synthesis of β-Hydroxy α-Amino Acids Through Brønsted Base-Catalyzed syn-Selective Direct Aldol Reaction of Schiff Bases of Glycine o-Nitroanilide

Here we report the highly enantio- and syn-selective synthesis of β-hydroxy α-amino acids from glycine imine derivatives under Brønsted base (BB) catalysis. The key of this approach is the use of benzophenone-derived imine of glycine o-nitroanilide as a pronucleophile, where the o-nitroanilide framework provides an efficient hydrogen-bonding platform that accounts for nucleophile reactivity and diastereoselectivity.Support has been provided by the University of the Basque Country UPV/EHU (UFI QOSYC 11/22), Basque Government (GV grant IT1236-19), and Ministerio de Ciencia e Innovación (MICINN, CTQ2016-78487-C2), Spain. A.V. thanks Basque Government, and I.U. and S.d.P. thank UPV/EHU. We also thank SGIker (UPV/EHU) for providing NMR, HRMS, X-ray, and computational resources

Caracterización de tipologías de productores de plátano (Musa AAB) en los Llanos Orientales de Colombia

The Llanos Orientales has traditionally been one of the most productive plantain regions. However, farmer´s classification has always been as small (1-5 ha), medium (6-15 ha) and big (> 15 ha) according to the planting area, without considering any other technical or economic criteria that would allow to differentiate plantain farmers in this area of the country. A economic, technical and social characterization of plantain producers in the departments of Meta, Casanare and Arauca was done based on a survey in the municipalities of Granada and Fuente de oro in Meta, Yopal and Pore in Casanare, Tame and Saravena in Arauca. The survey addressed all crop technical factors from soil preparation to post-harvest of plantain. Data analysis resulted in the following farmer´s typologies: 1. Producers with high productivity, technology and financial investment; 2. Producers with medium productivity, high technology and intermediate financial investment; 3. Producers with medium to low productivity, low technology and low financial investment and 4. Producers with low productivity, low technology and low financial investment. The results defined critical points for each typology and the facts to design work and research plans required to improve the production system for each type. Los Llanos Orientales ha sido tradicionalmente una de las regiones más productivas del cultivo de plátano. Sin embargo, la clasificación convencionalmente aplicada a los productores ha sido, como pequeño (1-5 ha), mediano (615 ha) y grande (>15 ha), sólo en función al área de siembra establecida, sin considerar ningún criterio técnico ni económico que permita identificar otros factores que logren diferenciar a los platanicultores de esta zona del país. Considerando esto, se realizó una caracterización técnica, económica y social de los tipos de productores de plátano en los departamentos de Meta, Casanare y Arauca con base a la información colectada a través de una encuesta aplicada. Los municipios seleccionados fueron Granada y Fuente de oro en el Meta, Yopal y Pore en Casanare, Tame y Saravena en Arauca. La encuesta abordó los aspectos técnicos del cultivo, permitiendo además obtener información de línea base que permitió el análisis del estado actual en cuanto adopción tecnológica de la región. Con el análisis de los datos obtenidos, se definieron las siguientes tipologías: 1. Productores con alta productividad, alta adopción tecnológica y alta inversión financiera; 2. Productores con mediana productividad, alta adopción tecnológica e inversión financiera intermedia; 3. Productores con mediana a baja productividad, baja adopción tecnológica y baja inversión financiera y 4. Productores con baja productividad, baja adopción tecnológica y baja inversión financiera. Con estos resultados, se definen los puntos críticos en cada tipología y de esta manera, diseñar los planes de trabajo e investigación requeridos para mejorar el sistema productivo para cada una de ellas

JAG1, MEF2C and BDNF polymorphisms associated with bone mineral density in women from Northern México

Introduction: Osteoporosis is characterized by a low bone mineral density. Genetic composition is one of the most influential factors in determining bone mineral density (BMD). There are few studies on genes associated with BMD in the Mexican population. Objective: To investigate the association of eight single nucleotide polymorphisms (SNP) of JAG1, MEF2C and BDNF genes with BMD in women of Northern México. Materials and methods: This study involved 124 unrelated Mexican women between 40 and 80 years old. BMD was determined by dual X-ray absorptiometry. Genotyping was performed using allelic discrimination by real time PCR. We analyzed the SNP of JAG1 (rs6514116, rs2273061, rs2235811 and rs6040061), MEF2C (rs1366594, rs12521522 and rs11951031), and BDNF (rs6265) and the data using linear regression. Results: The JAG1 SNP rs2235811 was associated with the BMD of the total body under the dominant inheritance model (p=0,024). Although the other SNPs were not associated with BMD in any of the inheritance models studied, a trend was observed. Conclusion: Our results suggest that the SNP rs2235811 in the JAG1 gene might contribute to the variation in BMD in women from northern México

Relationship between the folk uses of the granadilla plant (Passiflora ligularis juss) and its phytochemical composition

ABSTRACT: This article reports the common uses of the Passiflora ligularis juss among the farm workers in the department of Huila and the preliminary results of its phytochemical composition. In the first phase of this investigation, an ethnobotany survey distributed among 42 families was consulted to create an inventory of the agricultural uses of the different parts of the plant. This information served as a starting point to select the basic qualitative analysis which allows the identification of biological activity of this species such as the phytochemical analysis, the bromatological analysis, and the mineral analysis. Twenty six common uses were discovered especially for medical and nutritional purposes. Some medicinal uses may be related to the qualitative presence of compositions found in the phytochemical analysis. The use of the grenade’s outer shell for animal nutrition was found to be justified based on the calories and fiber. This study highlights the finding that the pulp of the fruit is a source of magnesium for children younger than a year. Significant differences were found in the composition of the grenade’s pulp of three different areas due to agroecological conditions and the mineral nutrition that the plants receive.RESUMEN: Este artículo reporta los usos populares de la Passiflora ligularis juss entre los campesinos del departamento del Huila y los resultados preliminares sobre su composición fitoquímica. En la primera etapa de esta investigación se hizo un inventario de los usos que los agricultores hacen de distintas partes de la planta con base en una encuesta etnobotánica realizada a 42 familias. Este conocimiento popular sirvió de punto de partida para seleccionar los análisis cualitativos básicos que permitieran identificar la actividad biológica de esta especie como la marcha fitoquímica, el análisis bromatológico y el análisis de minerales. Se encontraron 26 usos populares especialmente medicinales y alimenticios. Algunos usos medicinales podrían estar relacionados con la presencia cualitativa de compuestos hallados en la marcha fitoquímica. El empleo de la cáscara de granadilla para nutrición animal se encontró justificado por su aporte en calorías y en fibra. El estudio destaca el aporte de la pulpa de la fruta como fuente de magnesio para los niños menores de un año. Se encontraron diferencias significativas en la composición de la pulpa de granadilla de tres municipios debido a las condiciones agroecológicas y a la nutrición mineral a las que son sometidas las plantas

Functional and nutritional properties of six species of Passiflora (Passifloraceae) from the department of Huila, Colombia

ABSTRACT: We analyzed the functional and nutritional properties of six species of Passiflora (Passifloraceae) based on the uses reported by 74 farm families of ten municipalities of the Department of Huila in Colombia. The Ethnobotanical study allowed us to record 92 uses, most of which were medicinal, followed by the use of fruits for food. The phytochemical analysis of four species with the largest number of medicinal uses revealed the presence of phenolic compounds, triterpenes, steroids, and flavonoids, which would justify some of the uses reported by farmers. The nutritional analysis indicates that some of the fruits of Passiflora are high in Magnesium and Zinc, low in sodium, and have digestive properties.RESUMEN: Se analizan las propiedades funcionales y nutricionales de seis especies de Passiflora (Passifloraceae) a partir de los usos mencionados por 74 familias campesinas de 10 municipios del departamento del Huila en Colombia. El estudio etnobotánico permitió recoger 92 usos, de los cuales la mayoría son medicinales, seguidos de los usos de la fruta como alimento. El análisis fitoquímico de las cuatro especies con mayor número de usos medicinales evidenció la presencia de compuestos fenólicos, triterpenos, esteroides y flavonoides que justificarían algunos de los usos reportados por los agricultores. El análisis nutricional indica que algunas de las frutas de este género son una fuente importante de magnesio y de zinc, que son bajas en sodio y que tienen propiedades digestivas

Sensibilización a alérgenos alimentarios en pacientes del Servicio de Alergia del Hospital Universitario de la UANL, Monterrey

La alergia a alimentos ocurre en 2% a 8% de la población. La sensibilización a los alérgenos alimentarios puede ser detectada mediante pruebas cutáneas (PC). Objetivo: Evaluar la frecuencia de sensibilización a alérgenos alimentarios, en pacientes menores de 18 años, atendidos en el Servicio de Alergia del Hospital Universitario de Monterrey. ABSTRACT Food allergy occurs between 2%-8% of the population and sensitization to food allergens is detected by skin prick test (SPT). Objective: To assess the frequency of sensitization to food allergens in patients less than 18 years old attended in the Allergy Service of the University Hospital of the UANL in Monterrey

Erratun: G-force induced giant efficiency of nanoparticles internalization into living cells

The original version of this Article contained a typographical error in the spelling of the author Jose Luis F. Cuñado, which was incorrectly given as Jose Luis, F. Cuñad

An Energy-Reduced Mediterranean Diet, Physical Activity, and Body Composition

[ENG]Importance Strategies targeting body composition may help prevent chronic diseases in persons with excess weight, but randomized clinical trials evaluating lifestyle interventions have rarely reported effects on directly quantified body composition. OBJECTIVE To evaluate the effects of a lifestyle weight-loss intervention on changes in overall and regional body composition. DESIGN, SETTING, AND PARTICIPANTS The ongoing Prevención con Dieta Mediterránea-Plus (PREDIMED-Plus) randomized clinical trial is designed to test the effect of the intervention on cardiovascular disease prevention after 8 years of follow-up. The trial is being conducted in 23 Spanish research centers and includes men and women (age 55-75 years) with body mass index between 27 and 40 and metabolic syndrome. The trial reported herein is an interim subgroup analysis of the intermediate outcome body composition after 3-year follow-up, and data analysis was conducted from February 1 to November 30, 2022. Of 6874 total PREDIMED-Plus participants, a subsample of 1521 individuals, coming from centers with access to a dual energy x-ray absorptiometry device, underwent body composition measurements at 3 time points. INTERVENTION Participants were randomly allocated to a multifactorial intervention based on an energy-reduced Mediterranean diet (MedDiet) and increased physical activity (PA) or to a control group based on usual care, with advice to follow an ad libitum MedDiet, but no physical activity promotion. MAIN OUTCOMES AND MEASURES The outcomes (continuous) were 3-year changes in total fat and lean mass (expressed as percentages of body mass) and visceral fat (in grams), tested using multivariable linear mixed-effects models. Clinical relevance of changes in body components (dichotomous) was assessed based on 5% or more improvements in baseline values, using logistic regression. Main analyses were performed in the evaluable population (completers only) and in sensitivity analyses, multiple imputation was performed to include data of participants lost to follow-up (intention-to-treat analyses). RESULTS A total of 1521 individuals were included (mean [SD] age, 65.3 [5.0] years; 52.1% men). In comparison with the control group (n=761), participants in the intervention arm (n=760) showed greater reductions in the percentage of total fat (between group differences after 1-year, −0.94% [95% CI, −1.19 to −0.69]; 3 years, −0.38% [95% CI, −0.64 to −0.12] and visceral fat storage after 1 year, -126 g [95% CI, −179 to −73.3 g]; 3 years, −70.4 g [95% CI, −126 to −15.2 g] and greater increases in the percentage of total lean mass at 1 year, 0.88% [95% CI, 0.63%-1.12%]; 3-years 0.34% [95%CI, 0.09%-0.60%]). The intervention group was more likely to show improvements of 5% or more in baseline body components (absolute risk reduction after 1 year, 13% for total fat mass, 11% for total lean mass, and 14% for visceral fat mass; after 3-years: 6% for total fat mass, 6% for total lean mass, and 8% for visceral fat mass). The number of participants needed to treat was between 12 and 17 to attain at least 1 individual with possibly clinically meaningful improvements in body composition. CONCLUSIONS AND RELEVANCE The findings of this trial suggest a weight-loss lifestyle intervention based on an energy-reduced MedDiet and physical activity significantly reduced total and visceral fat and attenuated age-related losses of lean mass in older adults with overweight or obesity and metabolic syndrome. Continued follow-up is warranted to confirm the long-term consequences of these changes on cardiovascular clinical end points.S