Collective actions of women´s organizations for peace in Colombia

En la actualidad, Colombia está llevando a cabo un proceso de paz que podría vislumbrar la paz que ansía el país. Una paz que traería el final del conflicto armado pero no sistemáticamente el final de todo tipo de violencia. Para asegurar la participación e incidencia de las mujeres en el proceso, resulta indispensable conocer antes el papel que están desempeñando actualmente las redes de mujeres colombianas que luchan a favor de la paz. Es esto, precisamente, lo que pretende este manuscrito. A través de él, se exploran las principales formas de acción política de las mujeres colombianas que deciden articularse para luchar por la consecución y la construcción de la paz. Para ello, se analizan los principales repertorios de acción colectiva, la estructura organizativa, los marcos discursivos y los impactos de dos redes de mujeres —Ruta Pacífica de las Mujeres y Alianza Iniciativa de Mujeres Colombianas por la Paz—. Este análisis se ha llevado a cabo a través de técnicas cualitativas. Se han realizado, de este modo, tres entrevistas en profundidad con las principales lideresas de cada organización estudiada. Los resultados del análisis exponen, por un lado, cuáles son las diferencias y similitudes entre ambas redes a través de la observación de sus prácticas políticas y de la relación que mantienen con los conceptos paz/conflicto; y, género/feminismo. Mientras para la Ruta el eje articulador será el movimiento feminista, para la IPM lo será el marco institucional. Por otro lado, se identifican las resistencias civiles desarrolladas por las mujeres en los distintos procesos de paz colombianos, los límites encontrados por ellas mismas, las estrategias para superarlos y la salud política de estos movimientos.Currently, Colombia is conducting a peace process that could glimpse the peace the country craves. This peace would bring the end of the armed conflict but not systematically the end of all kind of violence. To ensure the participation and influence of women in this process, it is essential to know the current role performed by the Colombian women’s peace networks. This is the aim of this article. This article explores the main ways of political action undertaken by Colombian women in peacebuilding. In order to do it, we have analyzed the main repertoires of collective action, organizational structure, framing processes and impacts of two women’s networks —Women’s Pacific Route and the Initiative of Colombian Women for Peace—. This analysis was conducted using qualitative techniques. We have made thus three in-depth interviews with the main leaders of each organization studied. Our results present what are the differences and similarities between both women’s networks through the observation of their political practices and their relationship with the concepts peace/conflict; and gender/feminism. While for the Pacific Route the articulating axis is the feminist movement, for the IMP it is the institutional framework. On the other hand, we remarked on identifying civil resistance developed by women in the different Colombia’s peace processes, the limits found by themselves, the strategies to overcome them and the political health of these movements

Role of age and comorbidities in mortality of patients with infective endocarditis

[Purpose]: The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality. [Methods]: Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015.Patients were stratified into three age groups:<65 years,65 to 80 years,and ≥ 80 years.The area under the receiver-operating characteristic (AUROC) curve was calculated to quantify the diagnostic accuracy of the CCI to predict mortality risk. [Results]: A total of 3120 patients with IE (1327 < 65 years;1291 65-80 years;502 ≥ 80 years) were enrolled.Fever and heart failure were the most common presentations of IE, with no differences among age groups.Patients ≥80 years who underwent surgery were significantly lower compared with other age groups (14.3%,65 years; 20.5%,65-79 years; 31.3%,≥80 years). In-hospital mortality was lower in the <65-year group (20.3%,<65 years;30.1%,65-79 years;34.7%,≥80 years;p < 0.001) as well as 1-year mortality (3.2%, <65 years; 5.5%, 65-80 years;7.6%,≥80 years; p = 0.003).Independent predictors of mortality were age ≥ 80 years (hazard ratio [HR]:2.78;95% confidence interval [CI]:2.32–3.34), CCI ≥ 3 (HR:1.62; 95% CI:1.39–1.88),and non-performed surgery (HR:1.64;95% CI:11.16–1.58).When the three age groups were compared,the AUROC curve for CCI was significantly larger for patients aged <65 years(p < 0.001) for both in-hospital and 1-year mortality. [Conclusion]: There were no differences in the clinical presentation of IE between the groups. Age ≥ 80 years, high comorbidity (measured by CCI),and non-performance of surgery were independent predictors of mortality in patients with IE.CCI could help to identify those patients with IE and surgical indication who present a lower risk of in-hospital and 1-year mortality after surgery, especially in the <65-year group

Acciones colectivas de las organizaciones de mujeres por la paz en Colombia

Currently, Colombia is conducting a peace process that could glimpse the peace the country craves. This peace would bring the end of the armed conflict but not systematically the end of all kind of violence. To ensure the participation and influence of women in this process, it is essential to know the current role performed by the Colombian women’s peace networks. This is the aim of this article. This article explores the main ways of political action undertaken by Colombian women in peacebuilding. In order to do it, we have analyzed the main repertoires of collective action, organizational structure, framing processes and impacts of two women’s networks —Women’s Pacific Route and the Initiative of Colombian Women for Peace—. This analysis was conducted using qualitative techniques. We have made thus three in-depth interviews with the main leaders of each organization studied. Our results present what are the differences and similarities between both women’s networks through the observation of their political practices and their relationship with the concepts peace/conflict; and gender/feminism. While for the Pacific Route the articulating axis is the feminist movement, for the IMP it is the institutional framework. On the other hand, we remarked on identifying civil resistance developed by women in the different Colombia’s peace processes, the limits found by themselves, the strategies to overcome them and the political health of these movements.En la actualidad, Colombia está llevando a cabo un proceso de paz que podría vislumbrar la paz que ansía el país. Una paz que traería el final del conflicto armado pero no sistemáticamente el final de todo tipo de violencia. Para asegurar la participación e incidencia de las mujeres en el proceso, resulta indispensable conocer antes el papel que están desempeñando actualmente las redes de mujeres colombianas que luchan a favor de la paz. Es esto, precisamente, lo que pretende este manuscrito. A través de él, se exploran las principales formas de acción política de las mujeres colombianas que deciden articularse para luchar por la consecución y la construcción de la paz. Para ello, se analizan los principales repertorios de acción colectiva, la estructura organizativa, los marcos discursivos y los impactos de dos redes de mujeres —Ruta Pacífica de las Mujeres y Alianza Iniciativa de Mujeres Colombianas por la Paz—. Este análisis se ha llevado a cabo a través de técnicas cualitativas. Se han realizado, de este modo, tres entrevistas en profundidad con las principales lideresas de cada organización estudiada. Los resultados del análisis exponen, por un lado, cuáles son las diferencias y similitudes entre ambas redes a través de la observación de sus prácticas políticas y de la relación que mantienen con los conceptos paz/conflicto; y, género/feminismo. Mientras para la Ruta el eje articulador será el movimiento feminista, para la IPM lo será el marco institucional. Por otro lado, se identifican las resistencias civiles desarrolladas por las mujeres en los distintos procesos de paz colombianos, los límites encontrados por ellas mismas, las estrategias para superarlos y la salud política de estos movimientos

Prosthetic Valve Candida spp. Endocarditis: New Insights Into Long-term Prognosis—The ESCAPE Study

International audienceBackground: Prosthetic valve endocarditis caused by Candida spp. (PVE-C) is rare and devastating, with international guidelines based on expert recommendations supporting the combination of surgery and subsequent azole treatment.Methods: We retrospectively analyzed PVE-C cases collected in Spain and France between 2001 and 2015, with a focus on management and outcome.Results: Forty-six cases were followed up for a median of 9 months. Twenty-two patients (48%) had a history of endocarditis, 30 cases (65%) were nosocomial or healthcare related, and 9 (20%) patients were intravenous drug users. "Induction" therapy consisted mainly of liposomal amphotericin B (L-amB)-based (n = 21) or echinocandin-based therapy (n = 13). Overall, 19 patients (41%) were operated on. Patients <66 years old and without cardiac failure were more likely to undergo cardiac surgery (adjusted odds ratios [aORs], 6.80 [95% confidence interval [CI], 1.59-29.13] and 10.92 [1.15-104.06], respectively). Surgery was not associated with better survival rates at 6 months. Patients who received L-amB alone had a better 6-month survival rate than those who received an echinocandin alone (aOR, 13.52; 95% CI, 1.03-838.10). "Maintenance" fluconazole therapy, prescribed in 21 patients for a median duration of 13 months (range, 2-84 months), led to minor adverse effects.Conclusion: L-amB induction treatment improves survival in patients with PVE-C. Medical treatment followed by long-term maintenance fluconazole may be the best treatment option for frail patients

Contemporary use of cefazolin for MSSA infective endocarditis: analysis of a national prospective cohort

Objectives: This study aimed to assess the real use of cefazolin for methicillin-susceptible Staphylococcus aureus (MSSA) infective endocarditis (IE) in the Spanish National Endocarditis Database (GAMES) and to compare it with antistaphylococcal penicillin (ASP). Methods: Prospective cohort study with retrospective analysis of a cohort of MSSA IE treated with cloxacillin and/or cefazolin. Outcomes assessed were relapse; intra-hospital, overall, and endocarditis-related mortality; and adverse events. Risk of renal toxicity with each treatment was evaluated separately. Results: We included 631 IE episodes caused by MSSA treated with cloxacillin and/or cefazolin. Antibiotic treatment was cloxacillin, cefazolin, or both in 537 (85%), 57 (9%), and 37 (6%) episodes, respectively. Patients treated with cefazolin had significantly higher rates of comorbidities (median Charlson Index 7, P <0.01) and previous renal failure (57.9%, P <0.01). Patients treated with cloxacillin presented higher rates of septic shock (25%, P = 0.033) and new-onset or worsening renal failure (47.3%, P = 0.024) with significantly higher rates of in-hospital mortality (38.5%, P = 0.017). One-year IE-related mortality and rate of relapses were similar between treatment groups. None of the treatments were identified as risk or protective factors. Conclusion: Our results suggest that cefazolin is a valuable option for the treatment of MSSA IE, without differences in 1-year mortality or relapses compared with cloxacillin, and might be considered equally effective

Role of age and comorbidities in mortality of patients with infective endocarditis.

The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality. Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015.Patients were stratified into three age groups: A total of 3120 patients with IE (1327  There were no differences in the clinical presentation of IE between the groups. Age ≥ 80 years, high comorbidity (measured by CCI),and non-performance of surgery were independent predictors of mortality in patients with IE.CCI could help to identify those patients with IE and surgical indication who present a lower risk of in-hospital and 1-year mortality after surgery, especially in th