48 research outputs found

    Significados construidos da práticas em simulação clínica por estudantes de enfermagem

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    Objective: To describe the meanings that nursing students have built from clinical simulation experience to meet their learning needs. Methodology: The descriptive qualitative study from a hermeneutic paradigm. The design corresponds to an instrumental case study. A focus group and in-depth interviews were applied to 5th year students of the nursing career of Universidad Mayor Temuco, Chile, 2015. Data reduction was done from Atlas Ti software, version 7.0. The transcription of verbal data was developed from Jefferson transcription convention, which allowed the development of codification processes and analysis of narratives. Results: 4 categories emerged: Characteristics of clinical simulation, training expectations of clinical simulation, mobilized competencies and the importance of simulation for clinical practice. Within the observed results, students recognize that clinical simulation provides a safe and risk-free environment, they can integrate what they have learned in theory, into practice, without fear of causing harm to patients, being able to make mistakes, therefore,achieving meaningful learning. In addition, it allows the development of competencies such as teamwork, effective communication, problem solving, stress management and leadership. All this improves the confidence and safety of the student when facing real patients, promoting the delivery of quality nursing care, safeguarding the safety of users. Conclusion: Students value clinical simulation from a technical and personal perspective as a learning methodology that facilitates integration between theory and practice, promoting patient safety, self-confidence and security in the student.Objetivo: Describir los significados que han construido los estudiantes de enfermería a partir de la experiencia en simulación clínica para satisfacer sus necesidades de aprendizaje. Metodología: La metodología es cualitativa descriptiva, desde un paradigma hermenéutico. El diseño corresponde a un estudio de casos de tipo instrumental. Se aplicó un grupo focal y entrevistas en profundidad a estudiantes de 5° año de la carrera de enfermería de la Universidad Mayor Temuco, Chile, año 2015. La reducción de datos se hizo desde el software Atlas Ti, versión 7.0. La transcripción de la data verbal se desarrolló a partir del convencionalismo de Jefferson, lo que permitió el desarrollar procesos de codificación y análisis de narrativas. Resultados: Surgieron 4 categorías: Características de la simulación clínica, expectativas formativas simulación clínica, competencias movilizadas e importancia de la simulación para la práctica clínica. Dentro de los resultados observados, los estudiantes reconocen que la simulación clínica proporciona un entorno seguro y libre de riesgos, pueden integrar lo aprendido en la teoría a la práctica, sin temor de causar daño a los pacientes, pudiendo cometer errores, logrando así un aprendizaje significativo. Además, permite el desarrollo de competencias como trabajo en equipo, comunicación efectiva, resolución de problemas, manejo del estrés y liderazgo. Todo esto mejora la confianza y seguridad del estudiante al momento de enfrentarse al paciente real, promoviendo la entrega de cuidados enfermeros de calidad, resguardando la seguridad de los usuarios. Conclusión: Los estudiantes valoran desde una perspectiva técnica y personal la simulación clínica como una metodología de aprendizaje que facilita la integración entre teoría y práctica, promoviendo la seguridad del paciente, la autoconfianza y seguridad en el estudiante.Objetivo: Descrever os significados que os estudantes de enfermagem construíram a partir da experiência em simulação clínica para atender as suas necessidades de aprendizagem. Metodologia: Estudo descritivo qualitativo a partir de um paradigma hermenéutico. O design corresponde a um estudo de caso do tipo instrumental. Um grupo focal e entrevistas em profundidade foram aplicados aos alunos do quinto ano da carreira de enfermagem na Universidad Mayor Temuco, Chile, 2015. A redução de dados foi feita a partir do software Atlas Ti, versão 7.0. A transcrição de dados verbais foi desenvolvida a partir do convencionalismo de Jefferson, o que permitiu o desenvolvimento de processos de codificação e análise de narrativas. Resultados: Emergiram quatro categorias: Características da simulação clínica, expectativas formativas, simulação clínica, competências mobilizadas e importância da simulação para a prática clínica. Dentro dos resultados observados, os estudantes reconhecem que a simulação clínica proporciona um ambiente seguro e livre de riscos, eles podem integrar o que aprenderam na teoria à prática, sem medo de causar danos aos pacientes, sendo capazes de cometer erros, alcançando assim a aprendizagem. significativo Também permite o desenvolvimento de habilidades como trabalho em equipe, comunicação eficaz, resolução de problemas, gerenciamento de estresse e liderança. Tudo isso melhora a confiança e a segurança do aluno frente ao paciente real, promovendo a entrega de cuidados de enfermagem de qualidade, resguardando a segurança dos usuários. Conclusão: Os estudantes valorizam, de uma perspectiva técnica e pessoal, a simulação clínica como metodologia de aprendizagem que facilita a integração entre teoria e prática, promovendo a segurança do doente, a autoconfiança e a segurança no estudante

    Design of a low-cost equipment for optical hyperthermia

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    [EN] A laser equipment is presented which has been specifically designed for optical hyperthermia. Such specificity in the design has allowed implementation at costs significantly lower than other options currently available in the market. The developed equipment includes a 808 nm laser whose output power is up to 500 mW. It also incorporates additional devices that help the user in calibrating the system and supervising it while functioning. The performance of a prototype is tested by running two hyperthermia experiments: one involving gold nanorods, and the other using gold nanostars. The specific set-up of this prototype has allowed laser irradiation with radiated power densities up to 4W/cm(2). (C) 2016 Elsevier B.V. All rights reserved.This work has been carried out in the context of project "Development of electronic devices and equipment for detection and actuation based on new electronic technologies. Applications in the field of biomedicine" (grant number: MAT2015-64139-C4-3-R) and in coordination with project number MAT2015-64139-C4-1-R, both of them financed by the Spanish Ministry for Economy and Competitiveness in the framework of the Plan Estatal de Investigacion Cientifica y Tecnica y de Innovacion 2013-2016. Financial support from the Generalitat Valenciana (PROMETEOII/2014/047) and from the UPV (Erasmus Mundus EuroInkaNet project, 2013 call) are gratefully acknowledged too.Montes-Robles, R.; Hernández-Montoto, A.; Ibáñez Civera, FJ.; Masot Peris, R.; De La Torre-Paredes, C.; Martínez-Máñez, R.; Garcia-Breijo, E.... (2017). Design of a low-cost equipment for optical hyperthermia. Sensors and Actuators A Physical. 255:61-70. https://doi.org/10.1016/j.sna.2016.12.018S617025

    Tailoring basic and acidic properties of MgAl hydrotalcite by fluoride anions: Effect on glycerol oligomerisation

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    In this work, two families of catalysts based on mixed metal oxides derived from MgAl hydrotalcites were synthesized with a Mg/Al molar ratio of 3. On the one hand, in the first family, the fluoride anion was incorporated in the interlayer space by using ammonium fluoride, exploiting the “memory effect” characteristic of hydrotalcites. In the second family, fluoride anions substituted oxides anions in the layer, incorporating directly them during the precipitation of hydroxides, by using cryolite as a precursor for both fluorine and aluminium. The hydrotalcites were transformed into mixed metal oxides by thermal treatment and tested in the glycerol etherification reaction at 230 ºC, in a batch reactor at atmospheric pressure. The hydrotalcites and the corresponding mixed metal oxides were characterized by different experimental techniques, such as X-ray diffraction (XRD), elemental analysis (CHF), N2 sorption at -196ºC, thermogravimetric analysis (ATD-TG), X-ray photoelectron spectroscopy (XPS), temperature-programmed desorption of CO2 and NH3 (CO2-TPD and NH3-DTP) and solid state nuclear magnetic resonace (ssNMR) of 19F. It was found that the mixed metal oxides prepared from hydrotalcites, where fluorine was incorporated in the synthesis step using cryolite, achieved the maximum conversion values and complete selectivity towards diglycerol. Diglycerols were the unique detected products and, in some cases, the formation of triglycerols was also detected.Funding for open access charge: Universidad de Málaga / CBU

    Autosomal dominant polycystic kidney disease in young adults

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    Background The clinical manifestations of autosomal dominant polycystic kidney disease (ADPKD) usually appear in adulthood, however pediatric series report a high morbidity. The objective of the study was to analyze the clinical characteristics of ADPKD in young adults. Methods Family history, hypertension, albuminuria, estimated glomerular filtration rate (eGFR) and imaging tests were examined in 346 young adults (18-30 years old) out of 2521 patients in the Spanish ADPKD registry (REPQRAD). A literature review searched for reports on hypertension in series with more than 50 young (age <30 years) ADPKD patients. Results The mean age of this young adult cohort was 25.24 (SD 3.72) years. The mean age at diagnosis of hypertension was 21.15 (SD 4.62) years, while in the overall REPQRAD population was aged 37.6 years. The prevalence of hypertension was 28.03% and increased with age (18-24 years, 16.8%; 25-30 years, 36.8%). Although prevalence was lower in women than in men, the age at onset of hypertension (21 years) was similar in both sexes. Mean eGFR was 108 (SD 21) mL/min/1.73 m(2), 38.0% had liver cysts and 3.45% of those studied had intracranial aneurysms. In multivariate analyses, hematuria episodes and kidney length were independent predictors of hypertension (area under the curve 0.75). The prevalence of hypertension in 22 pediatric cohorts was 20%-40%, but no literature reports on hypertension in young ADPKD adults were found. Conclusions Young adults present non-negligible ADPKD-related morbidity. This supports the need for a thorough assessment of young adults at risk of ADPKD that allows early diagnosis and treatment of hypertension. Lay Summary Impairment of renal function usually develops from the fourth decade of life in autosomal dominant polycystic kidney disease (ADPKD). However, hypertension precedes the onset of renal insufficiency. In published pediatric series, the prevalence of hypertension is 20%-40%. However, clinical information on young adults with ADPKD is scarce. We present the largest cohort of young adults (age 18-30 years) with ADPKD published to date. Prevalence of hypertension is 28% and increases with age, reaching 36.8% in the subgroup aged 25-30 years, despite normal glomerular filtration rate and albuminuria. The prevalence of hypertension is higher in males, but the mean age at diagnosis (21 years) was similar in both sexes. Young adults present non-negligible ADPKD-related morbidity. This supports the need for a thorough assessment that allows early diagnosis and treatment of hypertension, before decline of estimated glomerular filtration rate. Ambulatory blood pressure monitoring may be especially useful in this regard.11 página

    Robust association between vascular habitats and patient prognosis in glioblastoma: an international retrospective multicenter study

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    This is the peer reviewed version of the following article: del Mar Álvarez-Torres, M., Juan-Albarracín, J., Fuster-Garcia, E., Bellvís-Bataller, F., Lorente, D., Reynés, G., Font de Mora, J., Aparici-Robles, F., Botella, C., Muñoz-Langa, J., Faubel, R., Asensio-Cuesta, S., García-Ferrando, G.A., Chelebian, E., Auger, C., Pineda, J., Rovira, A., Oleaga, L., Mollà-Olmos, E., Revert, A.J., Tshibanda, L., Crisi, G., Emblem, K.E., Martin, D., Due-Tønnessen, P., Meling, T.R., Filice, S., Sáez, C. and García-Gómez, J.M. (2020), Robust association between vascular habitats and patient prognosis in glioblastoma: An international multicenter study. J Magn Reson Imaging, 51: 1478-1486, which has been published in final form at https://doi.org/10.1002/jmri.26958. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.[EN] Background Glioblastoma (GBM) is the most aggressive primary brain tumor, characterized by a heterogeneous and abnormal vascularity. Subtypes of vascular habitats within the tumor and edema can be distinguished: high angiogenic tumor (HAT), low angiogenic tumor (LAT), infiltrated peripheral edema (IPE), and vasogenic peripheral edema (VPE). Purpose To validate the association between hemodynamic markers from vascular habitats and overall survival (OS) in glioblastoma patients, considering the intercenter variability of acquisition protocols. Study Type Multicenter retrospective study. Population In all, 184 glioblastoma patients from seven European centers participating in the NCT03439332 clinical study. Field Strength/Sequence 1.5T (for 54 patients) or 3.0T (for 130 patients). Pregadolinium and postgadolinium-based contrast agent-enhanced T-1-weighted MRI, T-2- and FLAIR T-2-weighted, and dynamic susceptibility contrast (DSC) T-2* perfusion. Assessment We analyzed preoperative MRIs to establish the association between the maximum relative cerebral blood volume (rCBV(max)) at each habitat with OS. Moreover, the stratification capabilities of the markers to divide patients into "vascular" groups were tested. The variability in the markers between individual centers was also assessed. Statistical Tests Uniparametric Cox regression; Kaplan-Meier test; Mann-Whitney test. Results The rCBV(max) derived from the HAT, LAT, and IPE habitats were significantly associated with patient OS (P < 0.05; hazard ratio [HR]: 1.05, 1.11, 1.28, respectively). Moreover, these markers can stratify patients into "moderate-" and "high-vascular" groups (P < 0.05). The Mann-Whitney test did not find significant differences among most of the centers in markers (HAT: P = 0.02-0.685; LAT: P = 0.010-0.769; IPE: P = 0.093-0.939; VPE: P = 0.016-1.000). Data Conclusion The rCBV(max) calculated in HAT, LAT, and IPE habitats have been validated as clinically relevant prognostic biomarkers for glioblastoma patients in the pretreatment stage. This study demonstrates the robustness of the hemodynamic tissue signature (HTS) habitats to assess the GBM vascular heterogeneity and their association with patient prognosis independently of intercenter variability. Technical Efficacy Stage: 2 J. Magn. Reson. Imaging 2019.This work was partially supported by: MTS4up project (National Plan for Scientific and Technical Research and Innovation 2013-2016, No. DPI2016-80054-R) (to J.M.G.G.); H2020-SC1-2016-CNECT Project (No. 727560) (to J.M.G.G.) and H2020-SC1-BHC-2018-2020 (No. 825750) (to J.M.G.G.); M.A.T was supported by DPI2016-80054-R (Programa Estatal de Promocion del Talento y su Empleabilidad en I + D + i). The data acquisition and curation of the Oslo University Hospital was supported by: the European Research Council (ERC) under the European Union's Horizon 2020 (Grant Agreement No. 758657), the South-Eastern Norway Regional Health Authority Grants 2017073 and 2013069, and the Research Council of Norway Grants 261984 (to K.E.E.). We gratefully acknowledge the support of NVIDIA Corporation with the donation of the Titan V GPU used for this research. E.F.G. was supported by the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No. 844646. Figure 1 was designed by the Science Artist Elena Poritskaya.Álvarez-Torres, MDM.; Juan-Albarracín, J.; Fuster García, E.; Bellvís-Bataller, F.; Lorente, D.; Reynés, G.; Font De Mora, J.... (2020). Robust association between vascular habitats and patient prognosis in glioblastoma: an international retrospective multicenter study. Journal of Magnetic Resonance Imaging. 51(5):1478-1486. https://doi.org/10.1002/jmri.2695814781486515Louis, D. N., Perry, A., Reifenberger, G., von Deimling, A., Figarella-Branger, D., Cavenee, W. K., … Ellison, D. W. (2016). The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary. Acta Neuropathologica, 131(6), 803-820. doi:10.1007/s00401-016-1545-1Gately, L., McLachlan, S., Dowling, A., & Philip, J. (2017). Life beyond a diagnosis of glioblastoma: a systematic review of the literature. Journal of Cancer Survivorship, 11(4), 447-452. doi:10.1007/s11764-017-0602-7Bae, S., Choi, Y. S., Ahn, S. S., Chang, J. H., Kang, S.-G., Kim, E. H., … Lee, S.-K. (2018). Radiomic MRI Phenotyping of Glioblastoma: Improving Survival Prediction. Radiology, 289(3), 797-806. doi:10.1148/radiol.2018180200Akbari, H., Macyszyn, L., Da, X., Wolf, R. L., Bilello, M., Verma, R., … Davatzikos, C. (2014). Pattern Analysis of Dynamic Susceptibility Contrast-enhanced MR Imaging Demonstrates Peritumoral Tissue Heterogeneity. Radiology, 273(2), 502-510. doi:10.1148/radiol.14132458Weis, S. M., & Cheresh, D. A. (2011). Tumor angiogenesis: molecular pathways and therapeutic targets. Nature Medicine, 17(11), 1359-1370. doi:10.1038/nm.2537De Palma, M., Biziato, D., & Petrova, T. V. (2017). Microenvironmental regulation of tumour angiogenesis. Nature Reviews Cancer, 17(8), 457-474. doi:10.1038/nrc.2017.51Jain, R., Poisson, L. M., Gutman, D., Scarpace, L., Hwang, S. N., Holder, C. A., … Flanders, A. (2014). Outcome Prediction in Patients with Glioblastoma by Using Imaging, Clinical, and Genomic Biomarkers: Focus on the Nonenhancing Component of the Tumor. Radiology, 272(2), 484-493. doi:10.1148/radiol.14131691Jensen, R. L., Mumert, M. L., Gillespie, D. L., Kinney, A. Y., Schabel, M. C., & Salzman, K. L. (2013). Preoperative dynamic contrast-enhanced MRI correlates with molecular markers of hypoxia and vascularity in specific areas of intratumoral microenvironment and is predictive of patient outcome. Neuro-Oncology, 16(2), 280-291. doi:10.1093/neuonc/not148Jena, A., Taneja, S., Gambhir, A., Mishra, A. K., D’souza, M. M., Verma, S. M., … Sogani, S. K. (2016). Glioma Recurrence Versus Radiation Necrosis. Clinical Nuclear Medicine, 41(5), e228-e236. doi:10.1097/rlu.0000000000001152Price, S. J., Young, A. M. H., Scotton, W. J., Ching, J., Mohsen, L. A., Boonzaier, N. R., … Larkin, T. J. (2015). Multimodal MRI can identify perfusion and metabolic changes in the invasive margin of glioblastomas. Journal of Magnetic Resonance Imaging, 43(2), 487-494. doi:10.1002/jmri.24996Chang, Y.-C. C., Ackerstaff, E., Tschudi, Y., Jimenez, B., Foltz, W., Fisher, C., … Stoyanova, R. (2017). Delineation of Tumor Habitats based on Dynamic Contrast Enhanced MRI. Scientific Reports, 7(1). doi:10.1038/s41598-017-09932-5Cui, Y., Tha, K. K., Terasaka, S., Yamaguchi, S., Wang, J., Kudo, K., … Li, R. (2016). Prognostic Imaging Biomarkers in Glioblastoma: Development and Independent Validation on the Basis of Multiregion and Quantitative Analysis of MR Images. Radiology, 278(2), 546-553. doi:10.1148/radiol.2015150358Juan-Albarracín, J., Fuster-Garcia, E., Pérez-Girbés, A., Aparici-Robles, F., Alberich-Bayarri, Á., Revert-Ventura, A., … García-Gómez, J. M. (2018). Glioblastoma: Vascular Habitats Detected at Preoperative Dynamic Susceptibility-weighted Contrast-enhanced Perfusion MR Imaging Predict Survival. Radiology, 287(3), 944-954. doi:10.1148/radiol.2017170845Fuster-Garcia, E., Juan-Albarracín, J., García-Ferrando, G. A., Martí-Bonmatí, L., Aparici-Robles, F., & García-Gómez, J. M. (2018). Improving the estimation of prognosis for glioblastoma patients by MR based hemodynamic tissue signatures. NMR in Biomedicine, 31(12), e4006. doi:10.1002/nbm.4006Abramson, R. G., Burton, K. R., Yu, J.-P. J., Scalzetti, E. M., Yankeelov, T. E., Rosenkrantz, A. B., … Subramaniam, R. M. (2015). Methods and Challenges in Quantitative Imaging Biomarker Development. Academic Radiology, 22(1), 25-32. doi:10.1016/j.acra.2014.09.001Stupp, R., Mason, W. P., van den Bent, M. J., Weller, M., Fisher, B., Taphoorn, M. J. B., … Mirimanoff, R. O. (2005). Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma. 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Journal of Cerebral Blood Flow & Metabolism, 36(8), 1319-1337. doi:10.1177/0271678x16647396Hirai, T., Murakami, R., Nakamura, H., Kitajima, M., Fukuoka, H., Sasao, A., … Yamashita, Y. (2008). Prognostic Value of Perfusion MR Imaging of High-Grade Astrocytomas: Long-Term Follow-Up Study. American Journal of Neuroradiology, 29(8), 1505-1510. doi:10.3174/ajnr.a1121Sawlani, R. N., Raizer, J., Horowitz, S. W., Shin, W., Grimm, S. A., Chandler, J. P., … Carroll, T. J. (2010). Glioblastoma: A Method for Predicting Response to Antiangiogenic Chemotherapy by Using MR Perfusion Imaging—Pilot Study. Radiology, 255(2), 622-628. doi:10.1148/radiol.10091341Hambardzumyan, D., & Bergers, G. (2015). Glioblastoma: Defining Tumor Niches. Trends in Cancer, 1(4), 252-265. doi:10.1016/j.trecan.2015.10.009Artzi, M., Bokstein, F., Blumenthal, D. T., Aizenstein, O., Liberman, G., Corn, B. W., & Ben Bashat, D. (2014). Differentiation between vasogenic-edema versus tumor-infiltrative area in patients with glioblastoma during bevacizumab therapy: A longitudinal MRI study. European Journal of Radiology, 83(7), 1250-1256. doi:10.1016/j.ejrad.2014.03.02

    Surgical treatment for colorectal cancer: Analysis of the influence of an enhanced recovery programme on long-term oncological outcomes-a study protocol for a prospective, multicentre, observational cohort study

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    Introduction The evidence currently available from enhanced recovery after surgery (ERAS) programmes concerns their benefits in the immediate postoperative period, but there is still very little evidence as to whether their correct implementation benefits patients in the long term. The working hypothesis here is that, due to the lower response to surgical aggression and lower rates of postoperative complications, ERAS protocols can reduce colorectal cancer-related mortality. The main objective of this study is to analyse the impact of an ERAS programme for colorectal cancer on 5-year survival. As secondary objectives, we propose to analyse the weight of each of the predefined items in the oncological results as well as the quality of life. Methods and analysis A multicentre prospective cohort study was conducted in patients older than 18 years of age who are scheduled to undergo surgery for colorectal cancer. The study involved 12 hospitals with an implemented enhanced recovery protocol according to the guidelines published by the Spanish National Health Service. The intervention group includes patients with a minimum implementation level of 70%, and the control group includes those who fail to reach this level. Compliance will be studied using 18 key performance indicators, and the results will be analysed using cancer survival indicators, including overall survival, cancer-specific survival and relapse-free survival. The time to recurrence, perioperative morbidity and mortality, hospital stay and quality of life will also be studied, the latter using the validated EuroQol Five questionnaire. The propensity index method will be used to create comparable treatment and control groups, and a multivariate regression will be used to study each variable. The Kaplan-Meier estimator will be used to estimate survival and the log-rank test to make comparisons. A p value of less than 0.05 (two-tailed) will be considered to be significant. Ethics and dissemination Ethical approval for this study was obtained from the Aragon Ethical Committee (C.P.-C.I. PI20/086) on 4 March 2020. The findings of this study will be submitted to peer-reviewed journals (BMJ Open, JAMA Surgery, Annals of Surgery, British Journal of Surgery). Abstracts will be submitted to relevant national and international meetings.The present research study was awarded a Ministerio de Ciencia e Innovación health research project grant (PI19/00291) from the Carlos III Institute of the Spanish National Health Service as part of the 2019 call for Strategic Action in Health

    Reflexiones desde el Desarrollo Regional

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    Capítulo 1: Rescatando el patrimonio cultural regional. Contenido: "Divulgación de las prácticas socioculturales relacionadas con la conservación, reproducción y usos que se da al cohombro (sicana odorifera) en diferentes comunidades de la Región de Occidente, Costa Rica" de Anyerline Marín Alfaro; "La fotografía como recurso documental para la reconstrucción visual de espacios históricos de San Ramón, Alajuela de 1890 a 1924" de María Verónica Solano Araya y Gustavo Fernández Jiménez. Capítulo 2: Estudios literarios reginales. Contenido: "Leolinda Daltro: Mujer, educadora e indigenista del siglo XIX" de Khellen Cristina Pires Correia Soares y Beleni Salete Grando; "Paratextualidad y discursos en 'Un viaje con Margareth'" de Yordan Arroyo Carvajal. Capítulo 3: Retos para el desarrollo desde lo regional. Contenido: "Estado de la situación de las microempresas en tres distritos del cantón de San Ramón, Alajuela" de Jeannette Morales Zumbado; "Capacidades de gobernanza e institucionalidad en los Consejos Cantonales de Coordinación Institucional" de Raúl Fonseca Hernández, Ana Cristina Quesada Monge y Ginnette Espinoza Palma; "Teorización de la propuesta de Desarrollo Humano Sostenible Local" de Ana Cristina Quesada Monge, Raúl Fonseca Hernández y María Fernanda Cortés Víquez. Capítulo 4: Medio ambiente y desarrollo. Contenido: "Gestión integrada del recurso hídrico (GIRH) y cambio climático en la parte alta de la microcuenca del río Poás, Alajuela (2019-2020)" de María José Chassoul Acosta, Ana Lorena Salmerón Alpízar y Rolando Alberto Marín León; "Estado de situación de las Organizaciones Comunitarias de Servicios de Agua y Saneamiento (OCSAS) en el cantón de San Ramón, Alajuela" de Adriana Muñoz Amores, Ana Carolina Méndez Montero y Jéssica Alejandra Mora Moya. Capítulo 5: Realidades socioeducativas. Contenido: "Competencias culturales en docentes y éxito académico en colegiales de diferentes orígenes étnico-culturales" de Carlos Yurán Chavarría Carranza; "Narrativas sexistas en el trap latinoamericano: Lenguaje, representaciones y apropiación" de Keylor Robles Murillo. Capítulo 6: En busca del bienestar de la población adulta mayor. Contenido: "La protección constitucional brasileña de la persona adulta mayor" de Juliana Mara Nespolo, Rodrigo Bordin y Maria de Lourdes Bernartt; "Danza, escritura y autobiografía en personas adultas mayores" de Andrea Molina Ovares y Damián Herrera González.El Centro de Investigaciones sobre Diversidad Cultural y Estudios Regionales busca, por medio de actividades académicas como coloquios internacionales, reunir a personas investigadoras de las sedes regionales de la Universidad de Costa Rica y de otras instituciones de educación superior a nivel nacional, regional e internacional, con el fin de propiciar encuentros de saberes que permitan compartir experiencias académicas e investigativas relacionadas con diversidad cultural y estudios regionales. Asimismo, gracias a su compromiso de contribuir en la comprensión y visibilización de los procesos culturales y los imaginarios regionales desde perspectivas inter, trans y multidisciplinarias para aportar al desarrollo integral de los distintos grupos humanos que conforman las sociedades actuales, realiza la divulgación de los hallazgos de este tipo de investigaciones, a través de publicaciones especiales. Es así como la presente publicación, derivada del VI Coloquio Internacional sobre Diversidad Cultural y Estudios Regionales desarrollado por el CIDICER en septiembre de 2021, compila trece artículos y ensayos, los cuales están organizados en seis capítulos que responden a diferentes áreas temáticasUniversidad de Costa Rica/[836-C0-723]/UCR/Costa RicaUCR::Sedes Regionales::Sede de Occidente::Recinto San Ramón::Centro de Investigaciones sobre Diversidad Cultural y Estudios Regionales (CIDICER
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