Mecanismos elementales del relato policiaco en un cuento de María Elena Bermúdez

El relato policiaco clásico obedece a un esquema muy preciso, el método científico decimonónico. Los elementos del texto construyen un combate de ingenios entre autor y lector en la solución de un crimen. Este mecanismo se manifiesta en Un cuarto en Ámsterdam de María Elena Bermúdez, donde las aparentes transgresiones de la historia confirman la eficacia del pensamiento lógico-deductivo

El soneto adaptado a Borges

El soneto fue una de las formas poéticas más recurridas por Jorge Luis Bor - ges en su producción durante la segunda mitad del siglo XX. Pero en la mayoría de estos poemas hay siempre algún tipo de variación que impide la identificación del escritor argentino con otros autores, lo que lleva a concluir que Borges empleó el sone - to de una manera particular para sus propios fines expresivos, sin apegarse al canon

Non-mandated reporters\u27 attitudes on reporting child abuse

The purpose of this study is to identify what barriers to reporting child abuse may exist within the population of non-mandated reporters. The number of child abuse reports being filed is on the rise and many of these reports are being evaluated out (not needing follow up)

Exploring intercultural sensitivity levels of Chinese and non-Chinese working together in China

Abstract. As societies and individuals from different cultural backgrounds interact, the cultivation of intercultural sensitivity becomes critical for the development of intercultural communication competence. China, and its growing number of crosscultural working environments, specially in the foreign language education sector are ideal for studying intercultural communication. However, and given the existing gap in research regarding intercultural sensitivity in this context, the present study analyzes what levels of intercultural sensitivity exist among Chinese and non-Chinese working together in crosscultural environments across China. At the same time, this study investigates which factors contribute to differentiating intercultural sensitivity levels among respondents. To answer these questions, a number of online surveys were conducted in order to examine background information from a group of Chinese and non-Chinese (N=62) working together in crosscultural environments across China. The Intercultural Sensitivity Scale (ISS) was used to measure intercultural sensitivity levels among respondents. Additionally, six interviews were conducted as complementary to the quantitative data. Results indicated that respondents scored high to very high levels of intercultural sensitivity across the five dimensions of the ISS. Furthermore, factors such as fluency in the host country’s language (Chinese mandarin) and having previous overseas study experience showed a significant impact on the level of intercultural sensitivity of participants. No statistically significant impact was found on factors such as gender, having close international contacts, nationality, and having a language teaching profession. Lastly, important differences were found in the reported experiences of participants in comparison to their IS levels in the areas of Respect for Cultural Differences, Interaction Engagement and Interaction Attentiveness. The findings in this study highlight the significance of having overseas study experience and foreign language ability as factors that contribute to higher levels of IS. Nevertheless, the comparison of quantitative and qualitative results suggest that the Intercultural Sensitivity Scale may require further examination as to how it captures the concept of IS

Predicting Prostate Cancer Aggressiveness through a Nanoparticle Test

Prostate cancer (PCa) is the most common malignancy and the second leading cause of cancer death in American men. Due to the lack of accurate tests to distinguish aggressive cancer from indolent tumor, prostate cancer is often over-treated. Post-surgery pathology analysis revealed that 30% of tumors removed by radical prostatectomy are deemed clinically insignificant and would not have required such invasive treatment.^1^ Over-diagnosis and treatment of low-risk prostate cancer has serious and long-lasting side effect: as high as 70% of the patients who receive radical prostatectomy treatment will suffer a loss of sexual potency that cannot be remedied by drugs such as sildenafil citrate.^2^ We herein report a simple nanoparticle-serum protein adsorption test that not only can distinguish prostate cancer from normal and benign conditions, but also is capable of predicting the aggressiveness of prostate cancer quantitatively. This new test could potentially deliver the long-expected and very much needed solution for better individualization of prostate cancer treatment

PERSPECTIVES ON THE BARRIERS ENCOUNTERED BY FOSTER YOUTH AT THE HIGHER EDUCATION LEVEL

The foster youth is a population in the child welfare arena where social workers continue to work and engage in providing effective and supportive resources. This population already vulnerable due to traumatic experiences, continue to lift the veil and fight against all odds. As change agents, we recognize their perspectives are critical to understanding and creating changes that will grant these youth higher academic success rates. This qualitative research includes thirteen open-ended questions regarding the perspectives of eleven former and current foster youth participants. Participants were provided the opportunity to identify the barriers they have face or are facing while attempted, attending and/or completing higher education. This insight provides an understanding of the views and obstacles that impede foster youths’ academic careers. Researchers distinguished barriers and explored options for these youths to meet higher academic success rates. Foster youths’ voices will be heard and will have a lasting imprint on students moving forward

Complejidad de caso en las diligencias preliminares y el derecho del imputado a ser investigado en un plazo razonable, en la Tercera Fiscalía Provincial de Huancayo, 2019.

El problema general de la presente es: ¿de qué manera la falta de motivación de la declaratoria de complejidad en las diligencias preliminares afecta el derecho al plazo razonable del investigado, en la Tercera Fiscalía Provincial de Huancayo, 2019?, siendo su objetivo general: determinar de qué manera la falta de motivación de la declaratoria de complejidad en las diligencias preliminares afecta el derecho al plazo razonable del investigado, en la Tercera Fiscalía Provincial de Huancayo, 2019. La hipótesis general planteada fue que: la falta de motivación de la declaratoria de complejidad en las diligencias preliminares afecta significativamente el derecho al plazo razonable del investigado, en la Tercera Fiscalía Provincial de Huancayo, 2019. “Los métodos generales que se utilizaron fueron el método inductivo-deductivo, siendo su tipo de investigación la de carácter jurídico dogmático, el nivel de investigación es de tipo explicativo, de diseño de investigación no experimental y de carácter transversal”. Como conclusión de la presente investigación se mencionado la siguiente: se ha determinado que la falta de motivación de la declaratoria de complejidad en las diligencias preliminares afecta significativamente el derecho al plazo razonable del investigado, en la Tercera Fiscalía Provincial de Huancayo, 2019. “La Corte Suprema de nuestro país debe como considerar como vinculante y de obligatoria aplicación, los fundamentos contenidos en la Casación Nro. 144-2012-Ancash, referidos a los plazos de ampliación para las diligencias preliminares, y no sólo a nivel de doctrina jurisprudencial”

β7 Integrin Inhibition Can Increase Intestinal Inflammation by Impairing Homing of CD25hiFoxP3+ Regulatory T Cells.

Background & aimsIntegrin α4β7 mediates lymphocyte trafficking to the gut and gut-associated lymphoid tissues, a process critical for recruitment of effector lymphocytes from the circulation to the gut mucosa in inflammatory bowel disease (IBD) and murine models of intestinal inflammation. Antibody blockade of β7 integrins generally is efficacious in IBD; however, some patients fail to respond, and a few patients can experience exacerbations. This study examined the effects of loss of β7 integrin function in murine models of IBD.MethodsIn a mouse IBD model caused by lack of interleukin 10, a cytokine important in CD25hiFoxP3+ regulatory T cell (Treg) function, genetic deletion of β7 integrin or antibody blockade of α4β7-mucosal addressin cell adhesion molecule-1 interaction paradoxically exacerbated colitis.ResultsLoss of β7 impaired the capacity of Tregs homing to the gut and therefore suppress intestinal inflammation in an adoptive T-cell transfer model; however, the intrinsic suppressive function of β7-deficient Tregs remained intact, indicating that the β7 deficiency selectively impacts gut homing. Deletion of β7 integrin did not worsen colitis in an acute dextran sodium sulfate model in which Treg number and function were normal.ConclusionsIn Integrin subunit beta (Itgb)7-/-Il10-/- mice, loss of β7-dependent Treg homing to gut-associated lymphoid tissues combined with loss of intrinsic Treg function exacerbated intestinal inflammation. These results suggest that IBD patients with reduced CD25hiFoxP3+ Treg numbers or function or lack of interleukin 10 could be at risk for failure of α4β7 blocking therapy

Inversor multinivel con reducción de pérdidas por conmutación

Actualmente en la industria son utilizados dos tipos de inversores, unos con conmutación en baja frecuencia y otros con conmutación en alta frecuencia por medio de PWM. Aquellos que manejan conmutación en baja frecuencia se caracterizan por que eliminan los armónicos más bajos por suma, así mismo eliminan contenido de frecuencia baja por medio de un filtro en la salida que se caracteriza por ser de impedancia alta. Debido a la baja frecuencia que manejan estos inversores en la conmutación, las perdidas asociadas a esta son bajas. Mientras que aquellos inversores que manejan alta frecuencia, eliminan contenido armónico por conmutación, permitiendo que el filtro a la salida sea de menor impedancia, pero generando mayores pérdidas en el inversor, reduciendo su eficiencia se propuso diseñar e implementar una nueva topología de un inversor el cual eliminara cierta cantidad de armónicos por conmutación en baja frecuencia utilizando dos puentes H, y utilizar un tercer puente H el cual al ser conmutado en alta frecuencia eliminaría los armónicos restantes obteniendo a la salida de los tres puentes una señal seno modulada, de la cual obtendríamos el promedio movil tras ser pasada por un filtro pasa bajos, resultando de este modo la señal sinusoidal deseada.Currently in the industry are used two types of investors, low frequency switching and others with high switching frequency using PWM. Those handling low frequency switching are characterized by eliminating the lowest harmonics by summation, also eliminates low frequency content by a filter on the output that is characterized by high impedance . Due to the low frequency handling these investors in the switching losses associated with this are low. While investors who handle high frequency harmonic content removed switched , allowing the filter to the output impedance is smaller , but larger losses in the inverter , reducing its efficiency is proposed to design and implement a new topology of an investor 's which eliminate certain amount of harmonics by switching at low frequencies using two H bridges, and H use a third bridge which to be switched in high frequency harmonics would eliminate remaining obtaining at the outlet of the three bridges sine modulated signal , which would obtain the moving average after being passed through a low pass filter , thus resulting the desired sinusoidal signal.Ingeniero (a) ElectrónicoPregrad