Voltammetric investigations of functional dyspepsia drug acotiamide at pencil graphite electrode: An eco-friendly and cost effective stripping detection method

First time, the electro-oxidative behaviour and determination of acotiamide at a pencil graphite electrode have been investigated under different experimental conditions using cyclic voltammetry (CV), differential pulse anodic stripping voltammetry (DPASV), and square wave anodic stripping voltammetric (SWASV) techniques. The voltammetric responses of acotiamide have been analyzed at different scan rates, pH and concentrations. Oxidation of acotiamide at the surface of pencil graphite electrode gave two well defined irreversible peaks in the voltammograms in BR buffer of pH 7.0. The oxidation process is completely diffusion controlled. A linear response of peak current has been obtained between 15.5 to 124 μM in non-aqueous media for all the voltammetric techniques. The proposed DPASV and SWASV techniques show limit of detection at 18.58 and 13.36 μM, respectively

Concomitant sutureless scleral fixation of intraocular lens with keratoplasty: Review of surgical techniques

Sutureless scleral fixation of intraocular lens (sSFIOL) is a commonly employed method of optical rehabilitation of aphakic patients with deficient capsular support, and corneal transplant surgeries can be simultaneously combined with sSFIOL to handle aphakic corneal opacities. A single-stage procedure circumvents the need for repeat intraocular procedures and carries lower risk of graft endothelial damage, endophthalmitis, and macular edema associated with sequential surgeries. However, it mandates surgical expertise and increases the chances of postoperative inflammation. A basket of options is available with the corneal surgeons regarding the manner of host and donor preparation as well as the approaches to scleral fixation and certain intraoperative modifications along with postoperative vigilance may enhance the surgical outcomes. Most of the studies pertaining to keratoplasty with sSFIOL categorize to case reports/series, surgical techniques, and retrospective studies with very limited prospective data available currently. The purpose of the present review is to consolidate all available literature on concomitant sSFIOLs and keratoplasty procedures

Voltammetric investigations of functional dyspepsia drug acotiamide at pencil graphite electrode: An eco-friendly and cost effective stripping detection method

124-130First time, the electro-oxidative behaviour and determination of acotiamide at a pencil graphite electrode have been investigated under different experimental conditions using cyclic voltammetry (CV), differential pulse anodic stripping voltammetry (DPASV), and square wave anodic stripping voltammetric (SWASV) techniques. The voltammetric responses of acotiamide have been analyzed at different scan rates, pH and concentrations. Oxidation of acotiamide at the surface of pencil graphite electrode gave two well defined irreversible peaks in the voltammograms in BR buffer of pH 7.0. The oxidation process is completely diffusion controlled. A linear response of peak current has been obtained between 15.5 to 124 μM in non-aqueous media for all the voltammetric techniques. The proposed DPASV and SWASV techniques show limit of detection at 18.58 and 13.36 μM, respectively