Powercoaching Program and Oral Discourse Competence of Grade 10 Students

Powercoaching is an intervention program which aims to enhance the oral discourse competence of the students. It highlights various activities that can help students with speaking difficulties. It was conducted among Grade 10 students of New Pangasinan National High School during the School Year 2019-2020. This study dealt to determine the level of effectiveness of the powercoaching program in terms of its content, relevance, instructional quality, and acceptability. Experimental research design was employed to determine the level of oral discourse competence of the students in terms of grammar, pronunciation, spontaneity, substance, organization, and diction. The findings of the study showed that the program was excellent and passed the quality standard set by the validators. The level of oral discourse competence of the students in their onset test were both in approaching proficient. The students were either struggling or have not acquired the knowledge, skills and understanding in public speaking. The difference between the levels of oral discourse competence of the students reveals that among the two groups of students, one group performed better in the outset test. The experimental group significantly increased their performance with proficient level compared to the control group. Moreover, there was a significant difference between the mean gain scores of the control and experimental groups. Students under experimental group have gained higher mean than the control group. Hence, the powercoaching program greatly influenced the students’ oral communicative competence. The developed program is then recommended for teachers’ utilization as part of their intervention strategies

Derecho laboral de los conductores de las empresas de transporte urbano en San Juan de Lurigancho-2018

La presente tesis titulada: “Derechos laboral de los conductores de las empresas de transporte urbano en San Juan de Lurigancho-2018”, tuvo como propósito describir la situación del conductor frente a las empresas de transporte y como tercer actor el Estado. La muestra estuvo conformada por 31 abogados de los diferentes juzgados laborales. Los datos fueron procesados en los programas de Microsoft Excel y Spss, donde se empleó el alfa de crombah como prueba estadística. Cabenellas (1968) nos dice que el derecho laboral es la relación o regulación entre el empleador, el empleado y en forma indirecta el Estado, donde se concluye que esta relación esta sesgada por conveniencia del empresario y no se cumple con otorgar los derechos laborales al conductor. Arévalo (2003) nos dice que la remuneración debe de ser efectuada por el empleador, situación que no se cumple según los resultados. Alonzo (2003) nos dice que la jornada de trabajo se debe realizar cumpliendo las 8 horas o 46 horas semanales, siendo los resultados que el conductor sobre pasa el tiempo de trabajo. Según Arévalo (2005) nos indica que los beneficios laborales son irrenunciables ya que es un derecho fundamental, pero en la realidad el empleador omite este derecho ya que alega que no existe vínculo laboral. El tipo de investigación es básica, de diseño no experimental, transeccional de alcance descriptivo. La población está determinada por los 72 trabajadores de los Juzgados Laborales en San Juan de Lurigancho y la muestra es no probabilística de opinión de expertos que serían los 31 especialistas de los Juzgados Laborales. Se concluye que no existe una relación laboral, la remuneración no es proporcionad por el empleador, la jornada de trabajo es excesivo y no se cumple con los beneficios laborales de los conductores de transporte urbano

Biodiversity of pig breeds from China and Europe estimated from pooled DNA samples: differences in microsatellite variation between two areas of domestication

Microsatellite diversity in European and Chinese pigs was assessed using a pooled sampling method on 52 European and 46 Chinese pig populations. A Neighbor Joining analysis on genetic distances revealed that European breeds were grouped together and showed little evidence for geographic structure, although a southern European and English group could tentatively be assigned. Populations from international breeds formed breed specific clusters. The Chinese breeds formed a second major group, with the Sino-European synthetic Tia Meslan in-between the two large clusters. Within Chinese breeds, in contrast to the European pigs, a large degree of geographic structure was noted, in line with previous classification schemes for Chinese pigs that were based on morphology and geography. The Northern Chinese breeds were most similar to the European breeds. Although some overlap exists, Chinese breeds showed a higher average degree of heterozygosity and genetic distance compared to European ones. Between breed diversity was even more pronounced and was the highest in the Central Chinese pigs, reflecting the geographically central position in China. Comparing correlations between genetic distance and heterozygosity revealed that China and Europe represent different domestication or breed formation processes. A likely cause is a more diverse wild boar population in Asia, but various other possible contributing factors are discussed

Servicios públicos de calidad como determinante de una Gestión Municipal eficiente en la zona de Chuquitanta 2018

La presente investigación titulada “SERVICIOS PÚBLICOS DE CALIDAD COMO DETERMINANTE DE UNA GESTIÓN MUNICIPAL EFICIENTE EN LA ZONA DE CHUQUITANTA 2018” tuvo como objetivo determinar en qué medida el buen funcionamiento de los servicios públicos establece la eficiencia de la gestión municipal en la zona de Chuquitanta del distrito de San Martín de Porres. Se utilizó el tipo investigación básica o teórica, en el nivel explicativo; para realizar la contrastación de la Hipótesis se utilizó los métodos generales; Método inductivodeductivo, método análisis – síntesis; así como métodos particulares como método exegético, método sistemático, método sociológico Con un Diseño No experimental transeccional, con una sola muestra. Para la Recolección de Información se utilizó Encuestas y Análisis Documental; llegándose a la conclusión de que la Municipalidad Distrital de San Martin de Porres tiene que mejorar mucho respecto dela calidad de los servicios públicos (Limpieza Pública, Parques y Jardines y Serenazgo), que brinda a los vecinos de la zona de Chuquitanta, en el actual contexto político y social, necesitan involucrar a las organizaciones vecinales a través de sus dirigentes para mejorar la recaudación, a sus trabajadores para mejorar la calidad del servicio a sus funcionarios que se involucren en resolver los problemas que se generan en dichos servicios a través de una gestión por resultados; ello que permita alcanzar el bienestar y mejorar la calidad de vida de sus vecinos, debemos tener en cuenta que por dichos servicios el contribuyente asume el costo, con el pago de sus arbitrios, Entre los principales resultados Se tiene el nivel promedio de funcionamiento del servicio de limpieza pública es de 53.89% catalogado como intermedio. En relación al nivel promedio de funcionamiento del servicio de mantenimiento de parques y jardines es de 52.61%; presenta el mismo comportamiento. Por otro lado, el nivel promedio de funcionamiento del servicio de seguridad ciudadana es de 53.49%; siguiendo la misma tendencia. En definitiva, el nivel promedio del funcionamiento de los servicios públicos seleccionados es de 53.58%; tomando esta información en consideración, se puede concluir que la percepción de los vecinos de la zona de Chuquitanta del distrito de San Martín de Porres con respecto a la implementación de servicios públicos y la calidad y bienestar es categorizada como de nivel intermedio; logrando de esta manera cumplir el objetivo general de la investigación. Por lo tanto, su gestión no es eficiente

Solution-phase racemization in the presence of an enantiopure solid phase.

Solution-phase racemization drives the evolution of single chirality in the solid phase by the "chiral amnesia" process first described by Viedma. The current investigations lay the basis for a better understanding of the mechanism of the solid-phase deracemization by uncoupling the chemical rate processes associated with the interconversion of enantiomers in the solution phase from the physical processes associated with solution-solid phase transfer via dissolution and reaccretion of molecules onto crystals. In addition, the enantiomer concentration profiles presented in this work, together with an analytical treatment of the racemization process in the presence of excess enantiopure solid, unequivocally reconfirm the validity of the Meyerhoffer double solubility rule for systems under solution racemization conditions

Retinol binding Protein-4 circulating levels were higher in nonalcoholic fatty liver disease vs. histologically normal liver from morbidly obese women.

We aimed to analyze the retinol binding protein-4 (RBP4) messenger RNA (mRNA) expression profiles in adipose tissues and liver of morbidly obese (MO) women with or without nonalcoholic fatty liver disease (NAFLD), and to study the relationships with other pro- and anti-inflammatory adipokines in vivo and in vitro. We performed a cross-sectional analysis of subcutaneous adipose tissue (SAT), visceral adipose tissue (VAT) and liver samples from four lean and 45 MO women with or without NAFLD by enzyme-linked immunosorbent assay and real-time reverse transcription-PCR. We also studied RBP4 expression in HepG2 hepatocytes under various inflammatory stimuli. Circulating RBP4 levels were higher in MO women, and specifically, in MO subjects with NAFLD compared with normal liver controls (lean and MO). RBP4 liver expression was higher in nonalcoholic steatohepatitis (NASH)-moderate/severe than in NASHmild. Overall RBP4 gene expression was higher in liver than in adipose tissues. Among them, the higher expression corresponded to SAT. VAT expression was lower in the MO cohort. In HepG2, RBP4 mRNA expression was reduced by tumor necrosis factor (TNF)-α and increased by adiponectin treatment. In conclusion, the results obtained in MO women with NAFLD, brings up the use of RBP4 and other adipokines as a panel of noninvasive molecular biomarkers when NAFLD is suspected. Further studies are needed with other obesity groups.Fil: Terra, Ximena. Universitat Rovira i Virgil. Departament de Medicina i Cirurgia; EspañaFil: Auguet, Teresa. Universitat Rovira i Virgil. Departament de Medicina i Cirurgia; España. Hospital Universitari Joan XXIII. Servei Medicina Interna,; EspañaFil: Broch, Montserrat. Universitat Rovira i Virgil. Departament de Medicina i Cirurgia; EspañaFil: Sabench, Fátima. Hospital Sant Joan de Reus. Servei de Cirurgia,; EspañaFil: Hernandez, Mercè. Hospital Sant Joan de Reus. Servei de Cirurgia,; EspañaFil: Pastor, Rosa M.. Hospital Universitari Joan XXIII. Laboratori de Bioquímica; EspañaFil: Quesada, Isabel María. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; Argentina. Universitat Rovira i Virgil. Departament de Medicina i Cirurgia; EspañaFil: Lunna, Ana. Universitat Rovira i Virgil. Departament de Medicina i Cirurgia; EspañaFil: Aguilar, Carmen. Universitat Rovira i Virgil. Departament de Medicina i Cirurgia; EspañaFil: Del Castillo, Daniel. Hospital Sant Joan de Reus. Servei de Cirurgia, ; EspañaFil: Richard, Cristobal. Universitat Rovira i Virgil. Departament de Medicina i Cirurgia; España. Hospital Universitari Joan XXIII. Servei Medicina Interna,; Españ

High expression of the MADS-box gene VRT2 increases the number of rudimentary basal spikelets in wheat

Spikelets are the fundamental building blocks of Poaceae inflorescences, and their development and branching patterns determine the various inflorescence architectures and grain yield of grasses. In wheat (Triticum aestivum), the central spikelets produce the most and largest grains, while spikelet size gradually decreases acropetally and basipetally, giving rise to the characteristic lanceolate shape of wheat spikes. The acropetal gradient corresponds with the developmental age of spikelets; however, the basal spikelets are developed first, and the cause of their small size and rudimentary development is unclear. Here, we adapted G&T-seq, a low-input transcriptomics approach, to characterize gene expression profiles within spatial sections of individual spikes before and after the establishment of the lanceolate shape. We observed larger differences in gene expression profiles between the apical, central, and basal sections of a single spike than between any section belonging to consecutive developmental time points. We found that SHORT VEGETATIVE PHASE MADS-box transcription factors, including VEGETATIVE TO REPRODUCTIVE TRANSITION 2 (VRT-A2), are expressed highest in the basal section of the wheat spike and display the opposite expression gradient to flowering E-class SEPALLATA1 genes. Based on multi-year field trials and transgenic lines, we show that higher expression of VRT-A2 in the basal sections of the spike is associated with increased numbers of rudimentary basal spikelets. Our results, supported by computational modeling, suggest that the delayed transition of basal spikelets from vegetative to floral developmental programs results in the lanceolate shape of wheat spikes. This study highlights the value of spatially resolved transcriptomics to gain insights into developmental genetics pathways of grass inflorescences

Биофизика зрительной сенсорной системы человека

Зрительная сенсорная система – это система, которая воспринимает излучение видимого спектра, после чего формируется изображение предметов окружающей среды в виде определенных ощущений (сенсорных чувств)

Guidance on noncorticosteroid systemic immunomodulatory therapy in noninfectious uveitis: fundamentals of care for uveitis (focus) initiative

Topic: An international, expert-led consensus initiative to develop systematic, evidence-based recommendations for the treatment of noninfectious uveitis in the era of biologics. Clinical Relevance: The availability of biologic agents for the treatment of human eye disease has altered practice patterns for the management of noninfectious uveitis. Current guidelines are insufficient to assure optimal use of noncorticosteroid systemic immunomodulatory agents. Methods: An international expert steering committee comprising 9 uveitis specialists (including both ophthalmologists and rheumatologists) identified clinical questions and, together with 6 bibliographic fellows trained in uveitis, conducted a Preferred Reporting Items for Systematic Reviews and Meta-Analyses protocol systematic reviewof the literature (English language studies from January 1996 through June 2016; Medline [OVID], the Central Cochrane library, EMBASE,CINAHL,SCOPUS,BIOSIS, andWeb of Science). Publications included randomized controlled trials, prospective and retrospective studies with sufficient follow-up, case series with 15 cases or more, peer-reviewed articles, and hand-searched conference abstracts from key conferences. The proposed statements were circulated among 130 international uveitis experts for review.Atotal of 44 globally representativegroupmembersmet in late 2016 to refine these guidelines using a modified Delphi technique and assigned Oxford levels of evidence. Results: In total, 10 questions were addressed resulting in 21 evidence-based guidance statements covering the following topics: when to start noncorticosteroid immunomodulatory therapy, including both biologic and nonbiologic agents; what data to collect before treatment; when to modify or withdraw treatment; how to select agents based on individual efficacy and safety profiles; and evidence in specific uveitic conditions. Shared decision-making, communication among providers and safety monitoring also were addressed as part of the recommendations. Pharmacoeconomic considerations were not addressed. Conclusions: Consensus guidelines were developed based on published literature, expert opinion, and practical experience to bridge the gap between clinical needs and medical evidence to support the treatment of patients with noninfectious uveitis with noncorticosteroid immunomodulatory agents