8 research outputs found
AIDS and United States Immigration Policy: Historical Stigmatization Continues With the Latest Loathsome Disease
- Publication venue
- St. John\u27s Law Scholarship Repository
- Publication date
- 04/05/2012
- Field of study
AIDS and United States Immigration Policy: Historical Stigmatization Continues With the Latest Loathsome Disease
- Publication venue
- St. John\u27s Law Scholarship Repository
- Publication date
- 04/05/2012
- Field of study
Phase II study of temozolomide in combination with topotecan (TOTEM) in relapsed or refractory neuroblastoma: A European Innovative Therapies for Children with Cancer-SIOP-European Neuroblastoma study.
- Author
- Angela Di Giannatale
- Annick Devos
- Ariane Boubaker
- Arnaud Verschuur
- Bagatell
- Birgit Geoerger
- Blaney
- Bomgaars
- Brodeur
- Carol
- Caroline Munzer
- Casey
- Christian M. Zwaan
- Daw
- De Sio
- Estlin
- Frederic Courbon
- Friedman
- Garaventa
- Hervé Rubie
- Houghton
- Houghton
- Isabelle Aerts
- Judith Landman-Parker
- Katty Malekzadeh
- Kieran Mc Hugh
- Kushner
- Kushner
- Kushner
- London
- London
- Loredana Amoroso
- Längler
- Marie-Cecile Le Deley
- Maris
- Matthay
- Michela Casanova
- Middlemas
- Mutter
- Nathalie Dias-Gastellier
- Nicholson
- Nitschke
- Park
- Pascal Chastagner
- Pourquier
- Pratt
- Riccardo Riccardi
- Rubie
- Rubie
- Santana
- Simon
- Stéphane Ducassoul
- Tisdale
- Tubergen
- Vassal
- Vassal
- Wagner
- Waud
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2014
- Field of study
PURPOSE: To assess objective response rate (ORR) after two cycles of temozolomide in combination with topotecan (TOTEM) in children with refractory or relapsed neuroblastoma.
PATIENTS AND METHODS: This multicenter, non-randomised, phase II study included children with neuroblastoma according to a two-stage Simon design. Eligibility criteria included relapsed or refractory, measurable or metaiodobenzylguanidine (mIBG) evaluable disease, no more than two lines of prior treatment. Temozolomide was administered orally at 150mg/m(2) followed by topotecan at 0.75mg/m(2) intravenously for five consecutive days every 28days. Tumour response was assessed every two cycles according to International Neuroblastoma Response Criteria (INRC), and reviewed independently.
RESULTS: Thirty-eight patients were enroled and treated in 15 European centres with a median age of 5.4years. Partial tumour response after two cycles was observed in 7 out of 38 evaluable patients [ORR 18%, 95% confidence interval (CI) 8-34%]. The best ORR whatever the time of evaluation was 24% (95% CI, 11-40%) with a median response duration of 8.5months. Tumour control rate (complete response (CR)+partial response (PR)+mixed response (MR)+stable disease (SD)) was 68% (95% CI, 63-90%). The 12-months Progression-Free and Overall Survival were 42% and 58% respectively. Among 213 treatment cycles (median 4, range 1-12 per patient) the most common treatment-related toxicities were haematologic. Grade 3/4 neutropenia occurred in 62% of courses in 89% of patients, grade 3/4 thrombocytopenia in 47% of courses in 71% of patients; three patients (8%) had febrile neutropenia.
CONCLUSION: Temozolomide-Topotecan combination results in very encouraging ORR and tumour control in children with heavily pretreated recurrent and refractory neuroblastoma with favourable toxicity profile
A comprehensive assessment of RNA-seq protocols for degraded and low-quantity samples
- Author
- A McKenna
- A Mortazavi
- Anita Fernandez
- C Wang
- D Degli Esposti
- D Ramskold
- DW Bryant
- EY Kang
- F Cunningham
- Guglielmo Roma
- H Shin
- I Gallego Romero
- J Barretina
- J Halvardson
- J Liang
- J Palacino
- JD McPherson
- Judith Knehr
- L Lin
- M Cieslik
- M Melé
- M Sultan
- M Sultan
- MA Tariq
- Marc Sultan
- MB Clark
- MJ Borad
- P Li
- S Hannedouche
- S Riccardi
- S Schuierer
- S Shanker
- S Zhao
- SA Byron
- SL Faherty
- SM-I Consortium
- Sven Schuierer
- T Hart
- T Junne
- V Costa
- Virginie Petitjean
- W Zhao
- Walter Carbone
- X Adiconis
- YS Niknafs
- Z Wang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Enhanced recycling of organic matter and Os-isotopic evidence for multiple magmatic or meteoritic inputs to the Late Permian Panthalassic Ocean, Opal Creek, Canada
- Author
- Algeo
- Algeo
- Algeo
- Algeo
- Algeo
- Arthur
- Berner
- Berner
- Berner
- Berner
- Bottini
- Brennecka
- Broecker
- Brookfield
- Burdige
- Canfield
- Charles M. Henderson
- Cohen
- Cohen
- Cornford
- Daly
- Dean
- Du Vivier
- D’Hondt
- Erwin
- Espitalié
- Esser
- French
- Georgiev
- Georgiev
- Georgiev
- Gorjan
- Gramlich
- Grasby
- Grice
- Hays
- Henderson
- Hermann
- Holly J. Stein
- Horan
- Hunt
- Isozaki
- Jaminski
- Joachimski
- Jorgensen
- Judith L. Hannah
- Kaiho
- Kaiho
- Kajiwara
- Kendall
- Knoll
- Koeberl
- Kristensen
- Kump
- Kump
- Li
- Luo
- Luo
- Lyons
- Lyons
- Meyer
- Meyer
- Newton
- Pašava
- Pegram
- Pegram
- Peters
- Petsch
- Peucker-Ehrenbrink
- Poulton
- Prahl
- Racki
- Raiswell
- Raiswell
- Raiswell
- Raiswell
- Rampino
- Ravizza
- Ravizza
- Riccardi
- Riccardi
- Romano
- Rooney
- Rothman
- Ryskin
- Schoepfer
- Schoepfer
- Scott
- Selby
- Shen
- Smoliar
- Song
- Song
- Sun
- Svensen
- Svetoslav V. Georgiev
- Takahashi
- Tejada
- Thomas J. Algeo
- Tripathy
- Turekian
- Turgeon
- Wignall
- Wilkin
- Xu
- Xu
- Xu
- Yang
- Zonneveld
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
The Characterisation of Pax3 Expressant Cells in Adult Peripheral Nerve
- Author
- A Theos
- A Tona
- AC LeBlanc
- AN Garratt
- BB Murinson
- C Fernandez-Valle
- C Ide
- C Keller
- C Kioussi
- C Lepper
- C Meier
- C Pritchard
- CE Wong
- CG Crist
- D Lang
- DE Syroid
- DH Gutmann
- DJ Epstein
- E Serra
- F Carlsen
- F Padilla
- F Relaix
- F Relaix
- FC Reeves
- G Sobue
- G Stoll
- G Stoll
- GM Kruger
- H Zheng
- HJ Weinberg
- I Adameyko
- J Ara
- J Djian-Zaouche
- JA Blake
- JB Grinspan
- JL Rutkowski
- JL Salzer
- Judith A. Blake
- JW Griffin
- JW Griffin
- K Cichowski
- K Takahashi
- K Tsukamoto
- KJ Fernandes
- KR Jessen
- L Li
- LM Davids
- M Osawa
- M Pongpudpunth
- M Tassabehji
- MD Goulding
- Melanie R. Ziman
- N Le
- P Kury
- P Murphy
- P Spreyer
- P Topilko
- P Topilko
- RG Pellegrino
- RR Baichwal
- S Chen
- S Masui
- S Medic
- S Ohta
- S Sheela
- SF Cramer
- SJ Venters
- SJ Xia
- SK Gupta
- SS Scherer
- TD Barber
- Thomas H. Gillingwater
- TR Gershon
- V Guenard
- V Salonen
- VA Botchkarev
- VF Gnocchi
- VH Perry
- VM Riccardi
- Y Wakamatsu
- Y Zhu
- Z Dong
- Z Dong
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
1994 Annual Selected Bibliography: Asian American Studies and the Crisis of Practice
- Author
- Abe Jennifer
- Abrahamse Allan F
- Abu-Lughod Janet
- Adler S. R.
- Affons Dyanne D
- Affonso Dyanne D
- Afkhami Mahnaz
- Agbayani-Siewert Pauline
- Agell Charlotte
- Agluca Jacqueline
- Agnew Vijay
- Ahlburg Dennis A
- Airriess Christopher A
- Akerman Harold
- Alan-Williams Gregory
- Aldama Frederick Luis
- Alexander G. R.
- Alexander H. A.
- Alexander Susan H
- Allen Ernest Jr
- Allison Maria T
- Almaguer
- Alston Dana
- Alva S. A.
- America
- Amott Teresa
- Anaya S. James.
- Ancheta Angelo
- Ancheta Angelo N
- Anderson J.
- Anderson Nick
- Anderton Douglas L
- Anh
- Anthias
- Anthias Floya
- Appleby Jerry L
- Archibald C. P.
- Artists
- Asia America
- Asian American Curriculum Project
- Asian American Institute
- Asian American Literature
- Asian American Studies Programs
- Asian and Pacific Islander Center for Census Information and Services.
- Asian Immigrant Women Advocates
- Asian Pacific American Film
- Atkinson D. R.
- Atkinson D. R. A.
- Attinasi John J
- Avanzo Carolyn Erickson
- Averbach Andrew P
- Avery Patricia
- Azar Sandra T
- Azuma Eiichiro
- Azuma Eiichiro
- Bach Robert L
- Badets Jane
- Bakan Abigail B
- Baker Michael
- Balakrishnan T. R.
- Banister Judith
- Bannerji Himani
- Banton Michael
- Barich Bill
- Barry Brian
- Bartik T. J.
- Batchelor Stephen
- Bates Eric
- Bates Timothy
- Bates Timothy
- Beach Charles M
- Beatty Bess
- Beck Roy
- Belkhir Jean
- Bemak Fred
- Benson Janet E
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- Berger Leslie
- Berkeley
- Berman Sanford
- Bernal Marta
- Betancourt H.
- Bhavnani
- Bibby Reginald W
- Bibby Reginald W
- Biegel Stuart
- Bittner Eric
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- Bonacich Edna
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- Calendish Marshall
- California Department of Health Services.
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- Carson California
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- Castles Stephen
- Center for Immigration Studies.
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- Chang Parris
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- Change
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- Chazanov Mathis
- Chen Moon S. Jr.
- Chen Moon S. Jr.
- Chen Zhongming Wang Xiao'ou
- Cheng Imm Tan
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- Cheung Y. W.
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- Chin Frank
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- Chin Jean Lau
- Chin Marilyn
- Chinatown Economic Development Council
- Chinen Joyce
- Chinese American Librarians Association
- Cho Milyoung
- Choi Hyup
- Chong-Gossard J. H.
- Chow Rey
- Choy Philip P
- Christensen Matthew
- Christofides L. N.
- Chu
- Chung Angie
- Chung Hoang Chuong
- Chung Rita
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- Cohen Rina
- Collin Robert W
- Coloma Roland Sintos
- Confucius Plaza
- Congress Elaine P
- Conroy Hilary
- Consul Wilma B
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- Dame Melvina Azar
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- Detroit
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- the United States
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- Tien Liang
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- Villalba
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- Wang Gungwu
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- Wong Deborah
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- Wu Edna
- Wu Jenai
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- Xiong Phua
- Ya Va Thai
- Yamamoto Hisaye
- Yamamoto Joe
- Yamamoto Yasushi
- Yamanaka Keiko
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- Yamato Alexander
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- Publication date
- Field of study
Asian American Religion: A Special Topics Bibliography
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- Christian Oral History Project
- Christian Oral History Project
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- Clark Karen
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- Coleman Graham
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- Communityof Faith
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- Haddad Yvonne Zazbeck
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- Hawaii
- Heifetz JulieAnn
- Ho Phu Xuan
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- Holy Cross
- Hong Peter Y
- Honolulu
- Hori Victor Sogen
- Hsu Chung-Chang
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- Kashima Tetsuden
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- Raphael's Parish
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- School Anniversary
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- Publication venue
- 'UCLA American Indian Studies Center'
- Publication date
- Field of study