Cibercrimen e informática forense : introducción y análisis en El Salvador

En este artículo se explica la situación de cibercrimen e informática forense, la importancia e interés dado por los gobiernos alrededor del mundo a este tema y un breve análisis enfocado en El Salvador a raíz de las medidas que abarcan leyes y políticas públicas referentes a ello. Finalmente se emite una crítica y conclusiones acerca del curso de la ciberseguridad en el país

How to interweave accessibility with didactic and technological quality of digital educational materials

Accessibility is a quality requirement for digital educational materials (or contents) in interactive learning environments. It ensures that students with disabilities do not face barriers when using such content. However, guaranteeing the accessibility of these materials is no easy task, at least for a significant part of the producers, evaluators, and users of educational materials, such as teachers. Proof of this can be found in the results of the case studies on the usability and reliability of technological accessibility evaluation standards conducted by Spanish Association for Standardisation (UNE) during the development of the Spanish Standard for the Quality of Digital Educational Materials UNE 71362. The results obtained show the difficulty of ensuring a good level of accessibility to digital educational materials, concluding that most creators and evaluators did not apply the guidelines due to either ignorance or difficulties. In order to minimise this problem, a new research approach has been taken based on unifying and abstracting the technology accessibility indicators from the regulations in force and integrating them, according to their applicability, transversally in the teaching and technological criteria of the new standard. This paper presents, explains and justifies this new approach in which the accessibility criteria are not isolated.Peer Reviewe

Herramienta de gestión de Modelos Ontológicos aplicados a la Mejora de Procesos Software

Resumen: Actualmente el software representa un componente principal en el desarrollo de las actividades dentro de las organizaciones. Este hecho hace que la calidad del software sea uno de los principales factores claves a los que se dedica mucho esfuerzo. La calidad del software permite de manera implícita la creación de valor agregado al software durante su desarrollo, resultando en un factor de competitividad en estas organizaciones. Éste trabajo propone una solución inteligente mediante el uso de gestión del conocimiento, con el fin de hacer que la aplicación de teorías de ingeniería de software, modelos y estándares de mejora de procesos sea de fácil implementación y a un menor costo. Específicamente, en este trabajo se presenta el desarrollo de un modelo ontológico basado el Cuerpo de Conocimientos de la Ingeniería de Software (SWEBOK por las siglas en inglés de Software Engineering Body of Knowledge) así como su aplicación práctica mediante un sistema software. Finalmente se presentan los resultados de la implementación de técnicas, métricas y actividades correspondientes al área de conocimiento de pruebas de software de SWEBOK. Así mismo se presentan resultados de la integración del marco base de datos de lenguaje ontológico web (OWLDB por las siglas en ingles ontology web language data base), con el objetivo de almacenar datos de manera persistente durante la aplicación. Palabras clave: Ontología, Cuerpo de Conocimientos de la Ingeniería de Software, SWEBOK, OWLDB, Bases de Datos, Mejora de procesos de software

Association of retinol binding protein4 (RBP4) and ghrelin plasma levels with insulin resistance and disease severity in non-diabetic patients with hidradenitis suppurativa

Hidradenitis suppurativa (HS) is a chronic inflammatory disease associated with insulin resistance (IR). Retinol binding protein 4 (RBP4) and ghrelin are two bioactive proteins that have been involved in glucose metabolism and IR, but also in the regulation of immune and inflammatory processes. The aim of this study was to determine the serum levels of RBP4 and ghrelin in patients with HS, and to assess the possible relationship between these levels and IR, disease severity and HS risk. A total of 137 subjects (77 HS patients and 60 controls) without diabetes mellitus were enrolled in this cross-sectional study. Patients with HS had significantly higher RBP4 but lower ghrelin plasma levels than controls, independently of body mass index (BMI). Serum RBP4 levels were positively correlated to disease severity and IR in HS patients. However, we found no association between ghrelin levels and any clinical or laboratory parameters. Moreover, high serum RBP4 and low ghrelin levels were associated with an increased risk for HS. Our results suggest that high RBP4 levels may be a surrogate biomarker for IR in patients with HS. Moreover, increased RBP4 and decreased ghrelin levels could also be independent risk factors for the development of HS

Evaluation of serum omentin-1 and apelin concentrations in patients with hidradenitis suppurativa

Introduction: Recent studies suggest a role of adipokines in the pathogenesis of hidradenitis suppurativa (HS). Omentin-1 and apelin are two recently identified adipokines that have been involved in the regulation of metabolic and inflammatory responses. Aim: To investigate serum omentin-1 and apelin levels in patients with HS and to assess their associations with metabolic parameters, disease severity and HS risk. Material and methods: This case-control study included 139 non-diabetic individuals (78 HS patients and 61 ageand sex-matched controls). Serum concentrations of omentin-1 and apelin and the homeostasis model assessment of insulin resistance (HOMA-IR) were measured in all participants. Results: Serum omentin-1 concentrations were significantly higher in HS patients compared to controls, whereas apelin serum levels did not significantly differ between both groups. These differences in omentin-1 concentrations remained significant even after adjusting for age, sex, and body mass index (BMI). The results of logistic regression analysis showed that increased omentin-1 plasma levels were an independent risk factor for HS. However, we found no association between serum levels of both omentin-1 and apelin with HS severity. Conclusions: Our results show that patients with HS have raised omentin-1 serum levels, which are associated with HS risk

Relative Risk Chart Score for the Assessment of the Cardiovascular Risk in Young Patients with Ankylosing Spondylitis

Objective. To determine if the use of the relative risk (RR) chart score may help to identify young ankylosing spondylitis (AS) patients at high risk of cardiovascular (CV) disease. Methods. 73 AS patients younger than 50 years were assessed. CV risk was calculated according to the total cholesterol systematic coronary risk evaluation (TC-SCORE) and the RR chart score. C-reactive protein (CRP) value at disease diagnosis and carotid ultrasound data were also analyzed. Results. Twenty (27.4%) patients exhibited carotid plaques being classified into the category of very highCVrisk.None of them was found to have a high/very high TC-SCORE. CRP > 3mg/L at disease diagnosis was associated with the presence of carotid plaques (odds ratio 5.66, \u1d45d� = 0.03).Whereas only 5 (14.2%) of the 35 patients with RR = 1 had carotid plaques, 15 (39.5%) of 38 with RR > 1 showed plaques. A model that included the performance of carotid US in patients with RR > 1 who hadCRP> 3mg/L allowed us to identify 60% of very high risk patients, with a specificity of 77.4%. Conclusions. RR chart score assessment may help to identify young AS patients at high risk of CV disease

Non-Native Plant Invasion along Elevation and Canopy Closure Gradients in a Middle Rocky Mountain Ecosystem

Mountain environments are currently among the ecosystems least invaded by non-native species; however, mountains are increasingly under threat of non-native plant invasion. The slow pace of exotic plant invasions in mountain ecosystems is likely due to a combination of low anthropogenic disturbances, low propagule supply, and extreme/steep environmental gradients. The importance of any one of these factors is debated and likely ecosystem dependent.We evaluated the importance of various correlates of plant invasions in the Wallowa Mountain Range of northeastern Oregon and explored whether non-native species distributions differed from native species along an elevation gradient. Vascular plant communities were sampled in summer 2012 along three mountain roads. Transects (n = 20) were evenly stratified by elevation (~70 m intervals) along each road. Vascular plant species abundances and environmental parameters were measured. We used indicator species analysis to identify habitat affinities for non-native species. Plots were ordinated in species space, joint plots and non-parametric multiplicative regression were used to relate species and community variation to environmental variables. Nonnative species richness decreased continuously with increasing elevation. In contrast, native species richness displayed a unimodal distribution with maximum richness occurring at mid–elevations. Species composition was strongly related to elevation and canopy openness. Overlays of trait and environmental factors onto non-metric multidimensional ordinations identified the montane-subalpine community transition and over-story canopy closure exceeding 60% as potential barriers to non-native species establishment. Unlike native species, non-native species showed little evidence for high-elevation or closed-canopy specialization. These data suggest that non-native plants currently found in the Wallowa Mountains are dependent on open canopies and disturbance for establishment in low and mid elevations. Current management objectives including restoration to more open canopies in dry Rocky Mountain forests, may increase immigration pressure of non-native plants from lower elevations into the montane and subalpine zones

"Tertius gaudens" : germplasm exchange networks and agroecological knowledge among home gardeners in the Iberian Peninsula

Background: The idea that knowledge flows through social networks is implicit in research on traditional knowledge, but researchers have paid scant attention to the role of social networks in shaping its distribution. We bridge those two bodies of research and investigate a) the structure of network of exchange of plant propagation material (germplasm) and b) the relation between a person's centrality in such network and his/her agroecological knowledge. Methods: We study 10 networks of germplasm exchange (n = 363) in mountain regions of the Iberian Peninsula. Data were collected through participant observation, semi-structured interviews, and a survey. Results: The networks display some structural characteristics (i.e., decentralization, presence of external actors) that could enhance the flow of knowledge and germplasm but also some characteristics that do not favor such flow (i.e., low density and fragmentation). We also find that a measure that captures the number of contacts of an individual in the germplasm exchange network is associated with the person's agroecological knowledge. Conclusion: Our findings highlight the importance of social relations in the construction of traditional knowledge

Henoch-Schönlein purpura in northern Spain: clinical spectrum of the disease in 417 patients from a single center

The severity of clinical features and the outcomes in previous series of patients reported with Henoch-Schönlein purpura (HSP) vary greatly, probably due to selection bias. To establish the actual clinical spectrum of HSP in all age groups using an unselected and wide series of patients diagnosed at a single center, we performed a retrospective review of 417 patients classified as having HSP according to the criteria proposed by Michel et al. Of 417 patients, 240 were male and 177 female, with a median age at the time of disease diagnosis of 7.5 years (interquartile range [IQR], 5.3-20.1 yr). Three-quarters of the patients were children or young people aged 20 years or younger (n = 315), and one-quarter were adults (n = 102). The most frequent precipitating events were a previous infection (38%), usually an upper respiratory tract infection, and/or drug intake (18.5%) shortly before the onset of the vasculitis. At disease onset the most common manifestations were skin lesions (55.9%), nephropathy (24%), gastrointestinal involvement (13.7%), joint symptoms (9.1%), and fever (6.2%). Cutaneous involvement occurring in all patients, mainly purpuric skin lesion, was the most common manifestation when the vasculitis was fully established, followed by gastrointestinal (64.5%), joint (63.1%), and renal involvement (41.2%). The main laboratory findings were leukocytosis (36.7%), anemia (8.9%), and increased serum IgA levels (31.7%). The most frequent therapies used were corticosteroids (35%), nonsteroidal antiinflammatory drugs (14%), and cytotoxic agents (5%). After a median follow-up of 12 months (IQR, 2-38 mo), complete recovery was observed in most cases (n = 346; 83.2%), while persistent, usually mild, nephropathy was observed in only 32 (7.7%) cases. Relapses were observed in almost a third of patients (n = 133; 31.9%).In conclusion, although HSP is a typical vasculitis affecting children and young people, it is not uncommon in adults. The prognosis is favorable in most cases, depending largely on renal involvement

La universidad y la promoción del cambio social

Aunque pensar en la universidad no es cosa nueva, y mucho menos pensar en el cambio social, sí resulta actual y necesaria la revisión de los esfuerzos universitarios modernos, traducidos en hechos concretos, porque forman parte de la dinámica de transformación social que se desarrolla en su entorno; cuestión que, en ocasiones, se desenvuelve frente a nosotros aún sin que podamos simplemente reconocerla. Para superar este estado de puro reconocimiento, múltiples universidades en el país han desarrollado modalidades diversas de participación en los grandes y pequeños procesos de cambio social intencionado. Ello ha cuestionado, en cierta medida, el ser y el quehacer de la propia universidad.ITESO, A.C.Fundación Friedrich NaumannPraxi