Bridging cultural heritage and communities through digital technologies: Understanding perspectives and challenges

We present and discuss the results of a qualitative study aimed at identifying what role interactive digital technologies could play in facilitating the participation of communities at risk of exclusion (particularly migrants and refugees) in cultural and heritage-related activities. Culture and heritage are known to be key factors in fostering social inclusion, and this has the potential for contributing to both the wellbeing of these communities and to cultural institutions themselves. Through surveys and interviews with two cohorts of participants (cultural heritage professionals and community facilitators), we gathered insights about their perspectives on how ICT tools could support their work with and for communities, as well as the challenges they face. This work sheds light on the opportunities and barriers surrounding the use of digital technologies for participation in the cultural heritage sector, which is timely due to the increasing focus on grassroots and community-led heritage initiatives and to the growing body of work on participatory ICT in disciplines such as human-computer interaction and community informatics

How effective is low vision service provision? A systematic review

Visual impairment is a large and growing socioeconomic problem. Good evidence on rehabilitation outcomes is required to guide service development and improve the lives of people with sight loss. Of the 478 potentially relevant articles identified, only 58 studies met our liberal inclusion criteria, and of these only 7 were randomized controlled trials. Although the literature is sufficient to confirm that rehabilitation services result in improved clinical and functional ability outcomes, the effects on mood, vision-related quality of life (QoL) and health-related QoL are less clear. There are some good data on the performance of particular types of intervention, but almost no useful data about outcomes in children, those of working age, and other groups. There were no reports on cost effectiveness. Overall, the number of well-designed and adequately reported studies is pitifully small; visual rehabilitation research needs higher quality research. We highlight study design and reporting considerations and suggest a future research agenda

The Molecular Origin and Taxonomy of Mucinous Ovarian Carcinoma

Mucinous ovarian carcinoma (MOC) is a unique subtype of ovarian cancer with an uncertain etiology, including whether it genuinely arises at the ovary or is metastatic disease from other organs. In addition, the molecular drivers of invasive progression, high-grade and metastatic disease are poorly defined. We perform genetic analysis of MOC across all histological grades, including benign and borderline mucinous ovarian tumors, and compare these to tumors from other potential extra-ovarian sites of origin. Here we show that MOC is distinct from tumors from other sites and supports a progressive model of evolution from borderline precursors to high-grade invasive MOC. Key drivers of progression identified are TP53 mutation and copy number aberrations, including a notable amplicon on 9p13. High copy number aberration burden is associated with worse prognosis in MOC. Our data conclusively demonstrate that MOC arise from benign and borderline precursors at the ovary and are not extra-ovarian metastases

Search for eccentric black hole coalescences during the third observing run of LIGO and Virgo

Despite the growing number of confident binary black hole coalescences observed through gravitational waves so far, the astrophysical origin of these binaries remains uncertain. Orbital eccentricity is one of the clearest tracers of binary formation channels. Identifying binary eccentricity, however, remains challenging due to the limited availability of gravitational waveforms that include effects of eccentricity. Here, we present observational results for a waveform-independent search sensitive to eccentric black hole coalescences, covering the third observing run (O3) of the LIGO and Virgo detectors. We identified no new high-significance candidates beyond those that were already identified with searches focusing on quasi-circular binaries. We determine the sensitivity of our search to high-mass (total mass M>70 M⊙) binaries covering eccentricities up to 0.3 at 15 Hz orbital frequency, and use this to compare model predictions to search results. Assuming all detections are indeed quasi-circular, for our fiducial population model, we place an upper limit for the merger rate density of high-mass binaries with eccentricities 0<e≤0.3 at 0.33 Gpc−3 yr−1 at 90\% confidence level

Lineage and Society in Precolonial Uganda

This article examines the changing nature of patrilineality in east-central Uganda from the sixth century. While traditional anthropological models of lineality have been largely dismissed in recent scholarship, the problem remains that patrilineages and patriclans have played important roles in the lives of the Ganda, Gwere, Soga and their North Nyanza ancestors. By carefully examining changes and continuities in the form and content of patrilineality it becomes possible to understand it as historically contingent. In North Nyanza, patrilineal descent was the norm for inheritance and for household formation, but relationships formed through mothers were also crucial in the creation of new communities and in the legitimation of political power. This was not static: as communities negotiated their changing circumstances, so they adapted the form of their particular patrilineality to serve their needs

Lineage and Society in Precolonial Uganda

This article examines the changing nature of patrilineality in east-central Uganda from the sixth century. While traditional anthropological models of lineality have been largely dismissed in recent scholarship, the problem remains that patrilineages and patriclans have played important roles in the lives of the Ganda, Gwere, Soga and their North Nyanza ancestors. By carefully examining changes and continuities in the form and content of patrilineality it becomes possible to understand it as historically contingent. In North Nyanza, patrilineal descent was the norm for inheritance and for household formation, but relationships formed through mothers were also crucial in the creation of new communities and in the legitimation of political power. This was not static: as communities negotiated their changing circumstances, so they adapted the form of their particular patrilineality to serve their needs