3,429 research outputs found

    Multivariate spline space over cross-cut partition

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    AbstractIn this paper, we mainly study the generator bases of the prime module determined by the global conformality condition of multivariate spline over star cross-cut partition. The results can help us to get the dimension and construct the spline bases for multivariate spline space over cross-cut partition, quasi-cross-cut partition, and super-cross-cut partition

    Geographic and Climatic Attributions of Autumn Land Surface Phenology Spatial Patterns in the Temperate Deciduous Broadleaf Forest of China

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    Autumn vegetation phenology plays a critical role in identifying the end of the growing season and its response to climate change. Using the six vegetation indices retrieved from moderate resolution imaging spectroradiometer data, we extracted an end date of the growing season (EOS) in the temperate deciduous broadleaf forest (TDBF) area of China. Then, we validated EOS with the ground-observed leaf fall date (LF) of dominant tree species at 27 sites and selected the best vegetation index. Moreover, we analyzed the spatial pattern of EOS based on the best vegetation index and its dependency on geo-location indicators and seasonal temperature/precipitation. Results show that the plant senescence reflectance index-based EOS agrees most closely with LF. Multi-year averaged EOS display latitudinal, longitudinal and altitudinal gradients. The altitudinal sensitivity of EOS became weaker from 2000 to 2012. Temperature-based spatial phenology modeling indicated that a 1 K spatial shift in seasonal mean temperature can cause a spatial shift of 2.4–3.6 days in EOS. The models explain between 54% and 73% of the variance in the EOS timing. However, the influence of seasonal precipitation on spatial variations of EOS was much weaker. Thus, spatial temperature variation controls the spatial patterns of EOS in TDBF of China, and future temperature increase might lead to more uniform autumn phenology across elevations

    Succinate metabolism: a promising therapeutic target for inflammation, ischemia/reperfusion injury and cancer

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    Succinate serves as an essential circulating metabolite within the tricarboxylic acid (TCA) cycle and functions as a substrate for succinate dehydrogenase (SDH), thereby contributing to energy production in fundamental mitochondrial metabolic pathways. Aberrant changes in succinate concentrations have been associated with pathological states, including chronic inflammation, ischemia/reperfusion (IR) injury, and cancer, resulting from the exaggerated response of specific immune cells, thereby rendering it a central area of investigation. Recent studies have elucidated the pivotal involvement of succinate and SDH in immunity beyond metabolic processes, particularly in the context of cancer. Current scientific endeavors are concentrated on comprehending the functional repercussions of metabolic modifications, specifically pertaining to succinate and SDH, in immune cells operating within a hypoxic milieu. The efficacy of targeting succinate and SDH alterations to manipulate immune cell functions in hypoxia-related diseases have been demonstrated. Consequently, a comprehensive understanding of succinate’s role in metabolism and the regulation of SDH is crucial for effectively targeting succinate and SDH as therapeutic interventions to influence the progression of specific diseases. This review provides a succinct overview of the latest advancements in comprehending the emerging functions of succinate and SDH in metabolic processes. Furthermore, it explores the involvement of succinate, an intermediary of the TCA cycle, in chronic inflammation, IR injury, and cancer, with particular emphasis on the mechanisms underlying succinate accumulation. This review critically assesses the potential of modulating succinate accumulation and metabolism within the hypoxic milieu as a means to combat various diseases. It explores potential targets for therapeutic interventions by focusing on succinate metabolism and the regulation of SDH in hypoxia-related disorders

    China's New-Type Urbanisation Plan (NUP) and the foreseeing challenges for decarbonization of cities: a review

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    The most recent urbanisation plan in China, the New-type Urbanisation Plan (NUP) launched in March 2014, is a national plan proposed for development of a scientific and reasonable urban development model by 2020. NUP aims to connect four major plans of ecological progress, urbanisation quality, expanding domestic demand and rural-urban coordination. After almost two years, several contradictions are already in place. However, there are key challenges for decarbonization of cities in this process. This review paper explores four major challenges and suggests steps forward during and after NUP's lifespan. This study also elaborates on the processes and contradictions for decarbonization of Chinese cities
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