5,462 research outputs found

    Three-body structure of low-lying 12Be states

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    We investigate to what extent a description of 12Be as a three-body system made of an inert 10Be-core and two neutrons is able to reproduce the experimental 12Be data. Three-body wave functions are obtained with the hyperspherical adiabatic expansion method. We study the discrete spectrum of 12Be, the structure of the different states, the predominant transition strengths, and the continuum energy spectrum after high energy fragmentation on a light target. Two 0+, one 2+, one 1- and one 0- bound states are found where the first four are known experimentally whereas the 0- is predicted as an isomeric state. An effective neutron charge, reproducing the measured B(E1) transition and the charge rms radius in 11Be, leads to a computed B(E1) transition strength for 12Be in agreement with the experimental value. For the E0 and E2 transitions the contributions from core excitations could be more significant. The experimental 10Be-neutron continuum energy spectrum is also well reproduced except in the energy region corresponding to the 3/2- resonance in 11Be where core excitations contribute.Comment: 16 pages, 9 figures. Accepted for publication in Physical Review

    Self-pulsing dynamics of ultrasound in a magnetoacoustic resonator

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    A theoretical model of parametric magnetostrictive generator of ultrasound is considered, taking into account magnetic and magnetoacoustic nonlinearities. The stability and temporal dynamics of the system is analized with standard techniques revealing that, for a given set of parameters, the model presents a homoclinic or saddle--loop bifurcation, which predicts that the ultrasound is emitted in the form of pulses or spikes with arbitrarily low frequency.Comment: 5 pages, 5 figure

    Excitability in a nonlinear magnetoacoustic resonator

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    We report a nonlinear acoustic system displaying excitability. The considered system is a magnetostrictive material where acoustic waves are parametrically generated. For a set of parameters, the system presents homoclinic and heteroclinic dynamics, whose boundaries define a excitability domain. The excitable behaviour is characterized by analyzing the response of the system to different external stimuli. Single spiking and bursting regimes have been identified.Comment: 4 pages, 5 figure

    The diacylglycerol kinase α/Atypical PKC/β1 integrin pathway in SDF-1α mammary carcinoma invasiveness

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    Diacylglycerol kinase α (DGKα), by phosphorylating diacylglycerol into phosphatidic acid, provides a key signal driving cell migration and matrix invasion. We previously demonstrated that in epithelial cells activation of DGKα activity promotes cytoskeletal remodeling and matrix invasion by recruiting atypical PKC at ruffling sites and by promoting RCP-mediated recycling of α5β1 integrin to the tip of pseudopods. In here we investigate the signaling pathway by which DGKα mediates SDF-1α-induced matrix invasion of MDA-MB-231 invasive breast carcinoma cells. Indeed we showed that, following SDF-1α stimulation, DGKα is activated and localized at cell protrusion, thus promoting their elongation and mediating SDF-1α induced MMP-9 metalloproteinase secretion and matrix invasion. Phosphatidic acid generated by DGKα promotes localization at cell protrusions of atypical PKCs which play an essential role downstream of DGKα by promoting Rac-mediated protrusion elongation and localized recruitment of β1 integrin and MMP-9. We finally demonstrate that activation of DGKα, atypical PKCs signaling and β1 integrin are all essential for MDA-MB-231 invasiveness. These data indicates the existence of a SDF-1α induced DGKα - atypical PKC - β1 integrin signaling pathway, which is essential for matrix invasion of carcinoma cells

    Magnetic properties of permalloy antidot arrayfabricated by interference lithography

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    The interference laser lithography and ion-beam sputtering have been reported. Magneto-optical Kerr effect magnetometry indicated that the sample exhibits four-fold anisotropic behaviour, i.e. different magnetization loops were observed when the external magnetic field was applied along either x-or y-axis, or along the array diagonal. Broadband ferromagnetic resonance measurements revealed a rich variety of different magnetization configurations in the unsaturated state that can be controlled by the orientation of the external magnetic field. Micromagnetic simulations have been performed to explain the observed results. On the contrary, in the saturated regime the system demonstrated almost isotropic magnetic behaviour that improves with external field increase. The obtained results show the potential of interference lithography for the fabrication of large area antidot arrays. (C) 2019 Author(s).The Portuguese team acknowledges the Network of Extreme Conditions Laboratories-NECL and Portuguese Foundation of Science and Technology (FCT) support through the projects NORTE-01-0145-FEDER-022096, MIT-EXPL/IRA/0012/2017, POCI-01-0145-FEDER-031302, EXPL/IF/01191/2013 (D.N.), EXPL/IF/00541/2015 (S.A.B.), EXPL/IF/00981/2013 (G.N.K). D.N., G.N.K., C.R and R.M. acknowledge the support by the European Union Horizon 2020 Research and Innovation Programme under Marie Sklodowska-Curie Grant Agreement EU H2020-MSCA-RISE-2016 (No 734801). The Spanish team acknowledges the support from Spanish MINECO through the grant FIS2016-76058 (AEI/FEDER, UE). A.H.-R. acknowledges the support from European Union's Horizon 2020 research and innovation program under the Marie Sklodowska-Curie Action (reference H2020-MSCA-IF-2016-746958). G.N.K. and O.V.D. acknowledge the support from European Cooperation in Science and Technology (COST) project CA16218 "NANOCOHYBRI.

    Three-body structure of low-lying 18Ne states

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    We investigate to what extent 18Ne can be descibed as a three-body system made of an inert 16O-core and two protons. We compare to experimental data and occasionally to shell model results. We obtain three-body wave functions with the hyperspherical adiabatic expansion method. We study the spectrum of 18Ne, the structure of the different states and the predominant transition strengths. Two 0+, two 2+, and one 4+ bound states are found where they are all known experimentally. Also one 3+ close to threshold is found and several negative parity states, 1-, 3-, 0-, 2-, most of them bound with respect to the 16O excited 3- state. The structures are extracted as partial wave components, as spatial sizes of matter and charge, and as probability distributions. Electromagnetic decay rates are calculated for these states. The dominating decay mode for the bound states is E2 and occasionally also M1.Comment: 17 pages, 5 figures (version to appear in EPJA

    Dissecting the long-term emission behaviour of the BL Lac object Mrk 421

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    We report on long-term multiwavelengthmonitoring of blazar Mrk 421 by the GLAST-AGILE Support Program of the Whole Earth Blazar Telescope (GASP-WEBT) collaboration and Steward Observatory, and by the Swift and Fermi satellites. We study the source behaviour in the period 2007–2015, characterized by several extreme flares. The ratio between the optical, X-ray and γ -ray fluxes is very variable. The γ -ray flux variations show a fair correlation with the optical ones starting from 2012.We analyse spectropolarimetric data and find wavelengthdependence of the polarization degree (P), which is compatible with the presence of the host galaxy, and no wavelength dependence of the electric vector polarization angle (EVPA). Optical polarimetry shows a lack of simple correlation between P and flux and wide rotations of the EVPA.We build broad-band spectral energy distributions with simultaneous near-infrared and optical data from the GASP-WEBT and ultraviolet and X-ray data from the Swift satellite. They show strong variability in both flux and X-ray spectral shape and suggest a shift of the synchrotron peak up to a factor of ∼50 in frequency. The interpretation of the flux and spectral variability is compatible with jet models including at least two emitting regions that can change their orientation with respect to the line of sight.http://10.0.4.69/mnras/stx2185Accepted manuscrip

    Pioglitazone Prevents Capillary Rarefaction in Streptozotocin-Diabetic Rats Independently of Glucose Control and Vascular Endothelial Growth Factor Expression

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    Background/Aims: Reduction of capillary network density occurs early in the development of metabolic syndrome and may be relevant for the precipitation of diabetes. Agonists of the peroxisome proliferator-activated receptor (PPAR)-gamma transcription factor are vasculoprotective, but their capacity for structural preservation of the microcirculation is unclear. Methods: Male Wistar rats were rendered diabetic by streptozotocin and treated with pioglitazone in chow for up to 12 weeks. Capillary density was determined in heart and skeletal muscle after platelet endothelial cell adhesion molecule-1 (PECAM-1) immunostaining. Hallmarks of apoptosis and angiogenesis were determined. Results: Capillary density deteriorated progressively in the presence of hyperglycemia (from 971/mm(2) to 475/mm(2) in quadriceps muscle during 13 weeks). Pioglitazone did not influence plasma glucose, left ventricular weight, or body weight but nearly doubled absolute and relative capillary densities compared to untreated controls (1.2 vs. 0.6 capillaries/myocyte in heart and 1.5 vs. 0.9 capillaries/myocyte in quadriceps muscle) after 13 weeks of diabetes. No antiapoptotic or angiogenic influence of pioglitazone was detected while a reduced expression of hypoxia-inducible factor-3 alpha and PPAR coactivator-1 alpha (PGC-1 alpha) mRNA as well as vascular endothelial growth factor (VEGF) protein possibly occurred as a consequence of improved vascularization. Conclusion: Pioglitazone preserves microvascular structure in diabetes independently of improvements in glycemic control and by a mechanism unrelated to VEGF-mediated angiogenesis. Copyright (C) 2012 S. Karger AG, Base

    Estudo da pollembrionia e crescimento inicial de jamboleiro (syzygium cumini l.).

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    O jamboleiro (Syzygium cumini L.) é uma árvore frondosa que pode alcançar mais de 20 m de altura, pertencente à família Myrtaceae. Tem origem na índia e é popularmente conhecido como jambolão, jamelão, azeitona doce ou jambul (VIZZOTTO; FETTER, 2009). Seu fruto é uma baga elipsóide com uma única semente, apresentando maturação em janeiro e fevereiro
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