Auroral evidence of radial transport at Jupiter during January 2014

We present Jovian auroral observations from the 2014 January Hubble Space Telescope (HST) campaign and investigate the auroral signatures of radial transport in the magnetosphere alongside contemporaneous radio and Hisaki EUV data. HST FUV auroral observations on day 11 show, for the first time, a significantly superrotating polar spot poleward of the main emission on the dawnside. The spot transitions from the polar to main emission region in the presence of a locally broad, bright dawnside main emission feature and two large equatorward emission features. Such a configuration of the main emission region is also unreported to date. We interpret the signatures as part of a sequence of inward radial transport processes. Hot plasma inflows from tail reconnection are thought to flow planetward and could generate the superrotating spot. The main emission feature could be the result of flow shears from prior hot inflows. Equatorward emissions are observed. These are evidence of hot plasma injections in the inner magnetosphere. The images are thought to be part of a prolonged period of reconnection. Radio emissions measured by Wind suggest that hectometric (HOM) and non-Io decametric (DAM) signatures are associated with the sequence of auroral signatures, which implies a global magnetospheric disturbance. The reconnection and injection interval can continue for several hours

OPEN COMMUNITY HEALTH: WORKSHOP REPORT

This report summarizes key outcomes from a workshop on open community health conducted at the University of Nebraska at Omaha in April 2018. Workshop members represented research and practice communities across Citizen Science, Open Source, and Wikipedia. The outcomes from the workshop include (1) comparisons among these communities, (2) how a shared understanding and assessment of open community health can be developed, and (3) a taxonomical comparison to begin a conversation between these communities that have developed disparate languages

Expressions 1985

PRODUCTION STAFFLOUISE AUSTINDANA Z. BEHRENDSENAMBER HEWITTTOSHIA SOUTHRANDY STANDLEYSHELLY WILSONhttps://openspace.dmacc.edu/expressions/1006/thumbnail.jp

One way or another? Criminal investigators' beliefs regarding the disclosure of evidence in interviews with suspects in England and Wales

The research base concerning interviews with suspects remains to be comprehensively developed. For example, the extant literature provides differing views regarding how best to undertake the important interview task of disclosing evidence. In the current study, using a self-report questionnaire, 224 investigators based in England and Wales were asked as to their own preferred methods. Most respondents advocated a gradual method of disclosing evidence, stating that this approach would better reveal inconsistencies and obtain a complete version of events (similar to the reasoning of those who preferred disclosing evidence later). Those who advocated revealing evidence early stated this approach would more likely elicit confessions. Several respondents would not commit to one single method, arguing that their chosen strategy was contextually dependent. The study’s findings suggest that it remains arguable as to whether there is one best approach to evidence disclosure and/or whether particular circumstances should influence interviewing strategies

International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways.

Primary biliary cirrhosis (PBC) is a classical autoimmune liver disease for which effective immunomodulatory therapy is lacking. Here we perform meta-analyses of discovery data sets from genome-wide association studies of European subjects (n=2,764 cases and 10,475 controls) followed by validation genotyping in an independent cohort (n=3,716 cases and 4,261 controls). We discover and validate six previously unknown risk loci for PBC (Pcombined<5 × 10(-8)) and used pathway analysis to identify JAK-STAT/IL12/IL27 signalling and cytokine-cytokine pathways, for which relevant therapies exist

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead