Primary Cutaneous Large B-Cell Lymphoma, Leg Type, Localized on the Dorsum

Primary cutaneous large B-cell lymphoma, leg-type (PCLBCL-LT), is a large B-cell lymphoma primarily involving the skin. It is distinguished from the other 3 subsets of this lymphoproliferative disorder by its immunohistopathological features, configuring confluent sheets of medium-sized to large B lymphocytes with round nuclei provided with evident nucleoli, resembling centroblasts or immunoblasts, which express Bcl-6, Bcl-2. Prevalently appearing on the lower limbs, as a single or multicentric and frequently ulcerated skin nodule or plaque, PCLBCL-LT has a worse prognosis than the other large B-cell lymphomas. Moreover, the age of onset is delayed (7th decade) compared to those of the other 3 subtypes (6th decade); it presents a slight female predominance (2:1), and a higher percentage of positivity to Bcl-2. We present a 52-year-old man who showed a 2-year standing, non-ulcerated, round, 4 cm in diameter, red plaque, medially located on the dorsum. After biopsy the diagnosis of PCLBCL-LT was made on histopathological and immunohistochemical studies, the latter showing positivity to CD20, Bcl-2, and Bcl-6. After treatment with radiotherapy the patient has shown a 4.4-year follow-up free of disease

Evaluation HPDC Lubricant Spraying for Improved Cooling and Die Protection

This study tries to find out a better cooling and temperature homogenization as well as better die protection on high-pressure die-casting (HPDC) spray lubrication. Test procedures have been set up to study the Leidenfrost point (LFP), contact angle (CA), film thickness and protection from die soldering of lubricants typically applied into the die surfaces during HPDC process. Five different lubricants have been studied as well as the influence in different controllable process parameters (type of die material, oxidation of the surface, temperature, roughness, droplet diameter, water hardness and lubricant concentration). The increase of the LFP, avoiding film boiling regime, and a reduced CA, improve the cooling and film ability of die surface during spraying. The best chemistry exhibits high LFP, shows an increased thickness of the formed film and is more effective preventing the sticking of the aluminum part to the die surface. Thermogravimetric analysis shows better thermal properties for lubricants with anti-sticking performance. The study performed and the test protocols set up result in a better insight of the involved phenomena and allow selecting the most favorable operating window for HPDC lubrication

WARM UP LUBE SYSTEM (WULS) RELATION BETWEEN A NEW APPROACH TO LUBRICATION DURING START-UP PHASES AND THE THERMAL SHOCK ON THE DIE SURFACE AND SCRAP REDUCTION

The continuous research for efficiency, associated with higher and higher quality standards in the different industrial production processes, has led, in the last few years, to further and more exhaustive analysis of the various machine cycle phases in the light alloy diecasting sector. The result of these studies was the development of new interdisciplinary technologies, which have firstly highlighted, and then solved “chronic” inefficiencies during the start-up phases. Today, the WULS system is able to optimize the Warm Up phase, being based on the die surface temperature value (thanks to the C.T.C. - acquisition module) and retroacting on the lubrication equipment. In this paper the authors present the WULS technology and highlight the existing relation between the Warm Up phase and the thermal shock generated on the die surface, emphasizing its high level of influence. It has been well shown by means of several tests in an Italian foundry that WULS technology, together with a specific warm-up phase lubricant, ensure: - decreasing thermal shock (approx. 66% of reduction in temperature drop) - reduction of scrap pieces during production starting (approx. - 50%)

Molossus rufus: distribuição geográfica e primeiro registro para Sergipe, nordeste do Brasil

Distributed throughout the world, Molossidae family consists of 18 genera and more than 100 species, 31 of which are found in Brazil. In this country, most of the records of Molossus rufus were taken in the southeast of the Atlantic Forest, with few records in the Cerrado and Caatinga. This study reports the first record of Molossus rufus for the state of Sergipe, northeastern Brazil. One lactating female was captured by mist nets, near buildings, in the Ibura National Forest (FLONA Ibura), in the beginning of the rainy season. This is the third species of molossid recorded to the state of Sergipe; the other two (Molossus molossus and Cynomops planirostris) were also recorded in human buildings.Keywords: Atlantic Forest, bats, Molossidae.Distribuída em todo o mundo, a família Molossidae consiste em 18 gêneros e mais de 100 species, 31 delas encontradas no Brasil. Nesse país, a maioria dos registros de Molossus rufus foi realizada no sudeste da Mata Atlântica, com poucos registros no Cerrado e Caatinga. Este estudo relata o primeiro registro de Molossus rufus para o estado de Sergipe, nordeste do Brasil. Uma fêmea lactante foi capturada com redes de neblina, próximo a edificações, na Floresta Nacional do Ibura (FLONA Ibura), no início da estação chuvosa. Esta é a terceira espécie de molossídeo registrada no estado de Sergipe, sendo que as outras duas (Molossus molossus e Cynomops planirostris) também foram registradas em construções humanas.Palavras-chave: Mata Atlântica, morcegos, Molossidae

ATLANTIC-PRIMATES: a dataset of communities and occurrences of primates in the Atlantic Forests of South America

Primates play an important role in ecosystem functioning and offer critical insights into human evolution, biology, behavior, and emerging infectious diseases. There are 26 primate species in the Atlantic Forests of South America, 19 of them endemic. We compiled a dataset of 5,472 georeferenced locations of 26 native and 1 introduced primate species, as hybrids in the genera Callithrix and Alouatta. The dataset includes 700 primate communities, 8,121 single species occurrences and 714 estimates of primate population sizes, covering most natural forest types of the tropical and subtropical Atlantic Forest of Brazil, Paraguay and Argentina and some other biomes. On average, primate communities of the Atlantic Forest harbor 2 ± 1 species (range = 1–6). However, about 40% of primate communities contain only one species. Alouatta guariba (N = 2,188 records) and Sapajus nigritus (N = 1,127) were the species with the most records. Callicebus barbarabrownae (N = 35), Leontopithecus caissara (N = 38), and Sapajus libidinosus (N = 41) were the species with the least records. Recorded primate densities varied from 0.004 individuals/km 2 (Alouatta guariba at Fragmento do Bugre, Paraná, Brazil) to 400 individuals/km 2 (Alouatta caraya in Santiago, Rio Grande do Sul, Brazil). Our dataset reflects disparity between the numerous primate census conducted in the Atlantic Forest, in contrast to the scarcity of estimates of population sizes and densities. With these data, researchers can develop different macroecological and regional level studies, focusing on communities, populations, species co-occurrence and distribution patterns. Moreover, the data can also be used to assess the consequences of fragmentation, defaunation, and disease outbreaks on different ecological processes, such as trophic cascades, species invasion or extinction, and community dynamics. There are no copyright restrictions. Please cite this Data Paper when the data are used in publications. We also request that researchers and teachers inform us of how they are using the data. © 2018 by the The Authors. Ecology © 2018 The Ecological Society of Americ

Terapia della dermatite atopica in base all'"Evidence Based Medicine".

TesisCuando un recién nacido por alguna patología es hospitalizado en la unidad de cuidados intensivos neonatales la familia se enfrenta a nuevas vivencias que amenazan la supervivencia familiar surgiendo en ellos sentimientos, emociones y reacciones; planteándose la interrogante: ¿Cómo son las vivencias de padres de recién nacidos hospitalizados en la Unidad de Cuidados Intensivos Neonatales del Hospital Nacional Almanzor Aguinaga Asenjo – EsSalud, Chiclayo 2016?, el objetivo comprender vivencias de padres de recién nacidos. La investigación fue cualitativa con enfoque estudio de caso. La muestra por saturación y redundancia; se utilizó entrevista semiestructurada a profundidad, generándose categorías: vivenciando sentimientos negativos ante la hospitalización de mi hijo: manifestando tristeza ante el sufrimiento de mi hijo, sintiendo culpa por la enfermedad de mi hijo;Teniendo fe y esperanza en la recuperación de mi hijo: teniendo fe en Dios, teniendo esperanza en la recuperación de mi hijo; Emergiendo emociones negativas frente a la hospitalización de mi hijo: miedo por la evolución de la enfermedad, angustia y ansiedad ante la enfermedad de mi hijo. La hospitalización: disminución del vínculo afectivo; Impacto emocional del padre frente a la hospitalización como apoyo conyugal y expresando agradecimiento con el personal de salud encargado del cuidado de mi hijo recien nacido. Concluyendo que los padres presentaron más sentimientos negativos que otra emoción o reacción

Intra-community coalitionary lethal attack of an adult male southern muriqui (Brachyteles arachnoides)

We report on the first evidence of intra-community coalitionary lethal aggression in muriquis (Brachyteles). The event occurred in southern muriquis (Brachyteles arachnoides) during a long-term study (>15 years) of two social groups inhabiting mostly pristine Atlantic forest habitat in the Parque Estadual Carlos Botelho, southern Sa˜o Paulo State, Brazil. The attack took place deep in the core area of the Group Caeteˆ home range. Tense agonistic behaviors and vocalizations preceded the lethal coalitionary attack, and the tension increased over a 36–48 hr period. One adult female and two unidentified individuals also took part in a coalition led by six adult males. The members of the coalition collectively approached, embraced, immobilized and repeatedly bit the entire body of an adult male, resulting in severe bleeding injuries and the victim’s death in less than 1 hr after the attack commenced. Combined ecological, behavioral and spatial data related to the event indicate that this was an intra-community attack and suggest social tensions related to mating competition as the proximate trigger of the coalitionary killing. The attack resembled those reported for chimpanzees, with clear numeric superiority and a low risk of injury to aggressors, resulting in the death of a lone conspecific victim. This observation (n=1) is suggestive of a capacity for escalated aggression in muriquis and reinforces arguments for the potential adaptive significance of intra-community aggression in male philopatric societies, as reported for spider monkeys and chimpanzees. These characteristics challenge the view of the muriquis as a peaceful primate and support the general hypothesis that imbalances of power contribute to intra-specific killing in primates, such as chimpanzees and humans