Recommendation of a security architecture for data loss prevention

Data and people are the most important assets of any organization. The amount of information that is generated increases exponentially due to the number of new devices that create information. On the other hand, more and more organizations are covered by some type of regulation, such as the General Data Protection Regulation. Organizations implement several security controls, however, they do not focus on protecting the information itself and information leakage is a reality and a growing concern. Based on this problem, there is a need to protect confidential information, such as clinical data, personal information, among others. In this regard, data loss prevention solutions (DLP – Data Loss Prevention) that have the ability to identify, monitor and act on data considered confidential, whether at the endpoint, data repositories or in the network, should be part of the information security strategy of organizations in order to mitigate these risks. This dissertation will study the topic of data loss prevention and evaluate several existing solutions in order to identify the key components of this type of solutions. The contribution of this work will be the recommendation of a security architecture that mitigates the risk of information leakage and that can be easily adaptable to any DLP solution to be implemented by organizations. In order to prove the efficiency of the architecture, it was implemented and tested to mitigate the risk of information leakage in specific proposed scenarios.A informação e as pessoas são os ativos mais importantes de qualquer organização. A quantidade de informação que é gerada aumenta exponencialmente devido à quantidade de novos dispositivos que produzem informação. Por outro lado, cada vez mais organizações são abrangidas por algum tipo de regulamento, como o Regulamento Geral de Proteção de Dados. As organizações implementam vários controlos de segurança, no entanto, não se focam na proteção da informação em si e a fuga da informação é uma realidade e uma preocupação crescente. Com base neste problema, existe a necessidade de proteger a informação confidencial, como dados clínicos, informação pessoal, entre outros. Neste sentido, as soluções de prevenção da fuga de informação (DLP – Data Loss Prevention) que têm a capacidade de identificar, monitorizar e atuar em dados considerados confidenciais, seja ao nível do endpoint, repositório de dados ou na rede, devem fazer parte da estratégia da segurança da informação das organizações por forma a mitigar estes riscos. Esta dissertação vai analisar a temática da prevenção da fuga de informação e avaliar várias soluções existentes com o propósito de identificar as componentes chave deste tipo de soluções. A principal contribuição deste trabalho será a recomendação de uma arquitetura de segurança que mitigue o risco da fuga da informação e que poderá ser facilmente adaptável a qualquer solução de DLP a ser implementada pelas organizações. Por forma a comprovar a eficiência da arquitetura, a mesma foi implementada e testada para mitigar o risco de fuga da informação em cenários específicos que foram definidos

Um estudo exploratório sobre a (in)existência de emoções em fetos no terceiro trimestre de gestação

Dissertação de Mestrado apresentada no ISPA – Instituto Universitário para obtenção de grau de Mestre na especialidade de Psicologia Clínica.Introdução teórica: A existência de uma vida mental pré-natal ou de um psiquismo embriónico é corroborado pelas emoções naturais, várias expressões faciais presentes a partir do 2º semestre de gestação, diferenciação de padrões do discurso emocional e por ter emoções. Objectivo: Pretende-se averiguar a (in)existência de emoções independentes das maternas, a partir das 34 semanas de gestação. Método: Estudo exploratório de delineamento experimental simples de grupos independentes aleatórios, constituído por três grupos experimentais pelos quais 93 participantes foram distribuídos aleatoriamente. Estas têm idades entre 17 e 40 anos, e os seus filhos têm entre 34 a 40 semanas de gestação. Mães e fetos foram expostas a estímulos musicais distintos durante a realização do CTG, após terem preenchido o MHI-5 e o questionário referente a dados demográficos, antecedentes pessoais e familiares. Analisou-se a frequência cardíaca fetal (FCF) e sua variação (VFCF) nos três grupos experimentais. Resultados: Não se observaram diferenças significativas em termos de FCF nos três grupos experimentais, porém constatam-se diferenças significativas ao nível da VFCF. Discussão: Apurou-se que o feto expressa uma independência ligeira da mãe que se poderá dever a uma continuidade mãe-feto veiculada pela placenta e por uma escassa individualidade e autonomia psíquica. Poderão ser usados métodos mais precisos que apreendam a integralidade do comportamento da FCF e da VFCF em estudos futuros. .Theoretical Background: The existence of pre-natal mental life, or an embryonic psyche, is corroborated by: the natural emotions; by the presence in the 2nd half of pregnancy of various facial expressions; by the differentiation of emotional pattern speech; and by fetal emotions. Objective: The aim of this study is to determine the (in) existence of fetal emotion independent of maternal emotions, from 34 weeks of gestation. Method: An exploratory study of 3 randomly assigned independent groups, with a total of 93 subjects. These are aged between 17 and 40 years, and their children are between 34-40 weeks of gestation. Mothers and fetuses were exposed to independant musical stimuli during the performance of a standard CTG reading performed at hospitals. In all three groups the mother listend to a medly of music varying from soft to hard. In one group the fetus had no music, in one the fetus had calm music, and in the third the fetus had the same variable music as the mother. Data was analyzed for heart rate (HR), and heart rate variability (HRV) as an indicator of emotional response, (McCraty studies). Results: The mother's HR and HRV showed no significant difference. The fetus' HRV showed small differences indicating a small degree of variability. Discussion: A slight independence from maternal emotions is found. It may be due to an mother-fetus continuity, where the placenta and an limited psychic individuality and autonomy can have a major role. More accurate mathematical data analysis methods which utilize the raw data files from the CTG machine may be used.

Active whey protein edible films and coatings incorporating lactic acid bacteria for fungi control in cheese

info:eu-repo/semantics/publishedVersio

Phenotypic and genotypic characteristics of shiga toxin-producing Escherichia coli strains isolated from children in São Paulo, Brazil

The biochemical and serological characteristics, virulence properties, and genetic relatedness of Shiga toxin-producing Escherichia coli (STEC) strains isolated in São Paulo, from April 1989 through March 1990, were determined. This is also the first report on clinic findings of human STEC infections in Brazil. The only three STEC strains identified in that period were lysine decarboxylase negative, belonged to serotype O111ac: non-motile, were Stx1 producers, carried the eae and astA genes, and 2 of them also presented the EHEC-hly sequence. The children carrying STEC were all boys, with less than two years old, and had no previous history of hospitalization. None of them presented blood in stools. Vomiting, cough and coryza were the most common clinical manifestations observed. Although the STEC strains were isolated during summer months, and presented similar phenotypic and genotypic characteristics, carbohydrate fermentation patterns and PFGE analysis suggested that these diarrheal episodes were not caused by a single clone.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de Microbiologia, Imunologia e ParasitologiaUSP Hospital das Clínicas Instituto da CriançaUniversidade Estadual do Rio de JaneiroUniversidade Federal Fluminense Departamento de Microbiologia e ParasitologiaUNIFESP, EPM, Depto. de Microbiologia, Imunologia e ParasitologiaSciEL

Intervenções não farmacológicas no controle da incontinência urinária e os instrumentos que permitam o seu diagnóstico: revisão integrativa

Introduction: Urinary incontinence is a major health problem resulting in physical, psychological and social changes with economic repercussions on the health system. Is a multifactorial condition associated with age-related changes and disorders of the genitourinary system, which corroborates the fact that it is the most often recurring geriatric syndrome. Aims: To identify non-pharmacological interventions for adults with urinary incontinence and to identify tools for urinary incontinence diagnosis in adults. Method: An integrative review study design was completed. Two electronic databases was search (MEDLINE and Web of Science). Three independent reviewers searched databases according to a predetermine inclusion and exclusion criteria. Results: Twelve articles were included in the review. Eleven articles mentioned non-pharmacological interventions, such as physical therapies, lifestyle strategies, behavioural therapies and alternative conservative management options. These interventions should be targeted and individualized to the type of incontinence to result in health gains for the population. One article mentioned an assessment tool for urinary incontinence - The Gaudenz-Fragebogen tool. The evaluation tools can help to systematize the diagnostic activity and consequently improve the clinical practice in the field of urinary incontinence. Conclusion: In care conception, nurses should target their interventions to personal data to address individual symptoms and use assessment tools that can help in the differential diagnosis of UI. Then, to advancing the quality and rigor of nursing care, we advocate that providing nurses with skills in attaining a differential diagnosis of UI presents an added value to the improvement of quality of care in a multidisciplinary context.info:eu-repo/semantics/publishedVersio

A Participação Popular na Formação dos Precedentes em Irdr No Cpc/15: Ampliação da Esfera Pública Habermasiana

The study aims, in the light of Habermas's theory, to evaluate the democratic participation in the formation of Incident of Resolution of Repetitive Demands mechanism provided in CCP/15 and able to form precedent to be followed by judges and courts of Brazil. In this sense, it’s clear that the provision of Art. 983, §1 of the CPC / 15, which enables the use of amicus curiae for training of judicial reasoning, materializes the proposal deliberative proposed by Habermas. Thus, complies with democratic development of the decision-making process, especially important when, by means of the decision, form a judicial precedent.O estudo visa, à luz da teoria habermasiana, avaliar a participação democrática na formação do Incidente de Resolução de Demandas Repetitivas, mecanismo previsto no CPC/15 e apto a formar precedente a ser seguido pelos juízes e tribunais do Brasil. Nesse sentido, percebe- se que a previsão do art. 983, §1º do CPC/15, a qual possibilita a utilização do amicus curiae para formação da fundamentação judicial, concretiza a proposta deliberativa proposta por Habermas.  Assim,  coaduna-se  com  a  necessidade  de  desenvolvimento  democrático  do processo decisório, importante principalmente quando se forma, por meio da decisão, um precedente judicial

Heart failure and health related quality of life

Quality of life is a major goal in the context of preventive and therapeutic cardiology. It is important, both as an outcome measure in clinical trials of congestive heart failure (CHF) and as a consideration in individual physicians' therapeutic decisions. In this article, quality of life concepts are reviewed, methods of measurement are explored and clinically significant changes on prognosis are discussed. There is a need for more research which is based on carefully selected measures of quality of life chosen as being of particular importance to patients and to the hypotheses being tested

GESTÃO ACADÊMICA DE CURSOS DE GRADUAÇÃO EM ADMINISTRAÇÃO: COMPARAÇÃO ENTRE UM CURSO PRESENCIAL E OUTRO A DISTÂNCIA

Discute-se o impacto da Educação a Distância (EaD) nos cursos de Administração, em relação aos tradicionais cursos do ensino presencial de Administração. Parte destas mudanças decorrem cada vez mais da utilização intensiva das Tecnologias de Informação e Comunicação (TICs), que alavancadas pela evolução tecnológica, estão potencializando seus usos cada vez mais na Educação. A expansão da EaD no Brasil iniciou-se em 2006, com a criação da Universidade Aberta do Brasil (UAB), que escolheu como projeto de implantação o Curso Piloto de Administração, o que veio a influenciar nas mudanças de cunho acadêmico e de gestão educacional nas universidades públicas brasileiras. Ilustra-se essas implicações pedagógicas e de gestão acadêmica com o estudo de caso de dos cursos de Administração de uma universidade estadual brasileira, onde demostra-se uma melhor performance do curso de Administração na modalidade a distância

MUMAL: multivariate analysis in shotgun proteomics using machine learning techniques.

BACKGROUND: The shotgun strategy (liquid chromatography coupled with tandem mass spectrometry) is widely applied for identification of proteins in complex mixtures. This method gives rise to thousands of spectra in a single run, which are interpreted by computational tools. Such tools normally use a protein database from which peptide sequences are extracted for matching with experimentally derived mass spectral data. After the database search, the correctness of obtained peptide-spectrum matches (PSMs) needs to be evaluated also by algorithms, as a manual curation of these huge datasets would be impractical. The target-decoy database strategy is largely used to perform spectrum evaluation. Nonetheless, this method has been applied without considering sensitivity, i.e., only error estimation is taken into account. A recently proposed method termed MUDE treats the target-decoy analysis as an optimization problem, where sensitivity is maximized. This method demonstrates a significant increase in the retrieved number of PSMs for a fixed error rate. However, the MUDE model is constructed in such a way that linear decision boundaries are established to separate correct from incorrect PSMs. Besides, the described heuristic for solving the optimization problem has to be executed many times to achieve a significant augmentation in sensitivity. RESULTS: Here, we propose a new method, termed MUMAL, for PSM assessment that is based on machine learning techniques. Our method can establish nonlinear decision boundaries, leading to a higher chance to retrieve more true positives. Furthermore, we need few iterations to achieve high sensitivities, strikingly shortening the running time of the whole process. Experiments show that our method achieves a considerably higher number of PSMs compared with standard tools such as MUDE, PeptideProphet, and typical target-decoy approaches. CONCLUSION: Our approach not only enhances the computational performance, and thus the turn around time of MS-based experiments in proteomics, but also improves the information content with benefits of a higher proteome coverage. This improvement, for instance, increases the chance to identify important drug targets or biomarkers for drug development or molecular diagnostics