Adaptive control for wearable robots in human-centered rehabilitation tasks

Robotic rehabilitation therapies have been improving by providing the needed assistance to the patient, in a human-centered environment, and also helping the therapist to choose the necessary procedure. This thesis presents an adaptive "Assistance-as-needed" strategy which adheres to the specific needs of the patient and with the inputs from the therapist, whenever needed. The exertion of assistive and responsive behavior of the lower limb wearable robot is dedicated for the rehabilitation of incomplete spinal cord injury (SCI) patients. The main objective is to propose and evaluate an adaptive control model on a wearable robot, assisting the user and adhering to their needs, with no or less combination of external devices. The adaptation must be more interactive to understand the user needs and their volitional orders. Similarly, by using the existing muscular strength, in incomplete SCI patients, as a motivation to pursue the movement and assist them, only when needed. The adaptive behavior of the wearable robot is proposed by monitoring the interaction and movement of the user. This adaptation is achieved by modulating the stiffness of the exoskeleton in function of joint parameters, such as positions and interaction torques. These joint parameters are measured from the user independently and then used to update the new stiffness value. The adaptive algorithm performs with no need of external sensors, making it simple in terms of usage. In terms of rehabilitation, it is also desirable to be compatible with combination of assistive devices such as muscle stimulation, neural activity (BMI) and body balance (Wii), to deliver a user friendly and effective therapy. Combination of two control approaches has been employed, to improve the efficiency of the adaptive control model and was evaluated using a wearable lower limb exoskeleton device, H1. The control approaches, Hierarchical and Task based approach have been used to assist the patient as needed and simultaneously motivate the patient to pursue the therapy. Hierarchical approach facilitates combination of multiple devices to deliver an effective therapy by categorizing the control architecture in two layers, Low level and High level control. Task-based approaches engage in each task individually and allow the possibility to combine them at any point of time. It is also necessary to provide an interaction based approach to ensure the complete involvement of the user and for an effective therapy. By means of this dissertation, a task based adaptive control is proposed, in function of human-orthosis interaction, which is applied on a hierarchical control scheme. This control scheme is employed in a wearable robot, with the intention to be applied or accommodated to different pathologies, with its adaptive capabilities. The adaptive control model for gait assistance provides a comprehensive solution through a single implementation: Adaptation inside a gait cycle, continuous support through gait training and in real time. The performance of this control model has been evaluated with healthy subjects, as a preliminary study, and with paraplegic patients. Results of the healthy subjects showed a significant change in the pattern of the interaction torques, elucidating a change in the effort and adaptation to the user movement. In case of patients, the adaptation showed a significant improvement in the joint performance (flexion/extension range) and change in interaction torques. The change in interaction torques (positive to negative) reflects the active participation of the patient, which also explained the adaptive performance. The patients also reported that the movement of the exoskeleton is flexible and the walking patterns were similar to their own distinct patterns. The presented work is performed as part of the project HYPER, funded by Ministerio de Ciencia y Innovación, Spain. (CSD2009 - 00067 CONSOLIDER INGENIOLas terapias de rehabilitación robóticas han sido mejoradas gracias a la inclusión de la asistencia bajo demanda, adaptada a las variaciones de las necesidades del paciente, así como a la inclusión de la ayuda al terapeuta en la elección del procedimiento necesario. Esta tesis presenta una estrategia adaptativa de asistencia bajo demanda, la cual se ajusta a las necesidades específicas del paciente junto a las aportaciones del terapeuta siempre que sea necesario. El esfuerzo del comportamiento asistencial y receptivo del robot personal portátil para extremidades inferiores está dedicado a la rehabilitación de pacientes con lesión de la médula espinal (LME) incompleta. El objetivo principal es proponer y evaluar un modelo de control adaptativo en un robot portátil, ayudando al usuario y cumpliendo con sus necesidades, en ausencia o con reducción de dispositivos externos. La adaptación debe ser más interactiva para entender las necesidades del usuario y sus intenciones u órdenes volitivas. De modo similar, usando la fuerza muscular existente (en pacientes con LME incompleta) como motivación para lograr el movimiento y asistirles solo cuando sea necesario. El comportamiento adaptativo del robot portátil se propone mediante la monitorización de la interacción y movimiento del usuario. Esta adaptación conjunta se consigue modulando la rigidez en función de los parámetros de la articulación, tales como posiciones y pares de torsión. Dichos parámetros se miden del usuario de forma independiente y posteriormente se usan para actualizar el nuevo valor de la rigidez. El desempeño del algoritmo adaptativo no requiere de sensores externos, lo que favorece la simplicidad de su uso. Para una adecuada rehabilitación, efectiva y accesible para el usuario, es necesaria la compatibilidad con diversos mecanismos de asistencia tales como estimulación muscular, actividad neuronal y equilibrio corporal. Para mejorar la eficiencia del modelo de control adaptativo se ha empleado una combinación de dos enfoques de control, y para su evaluación se ha utilizado un exoesqueleto robótico H1. Los enfoques de control Jerárquico y de Tarea se han utilizado para ayudar al usuario según sea necesario, y al mismo tiempo motivarle para continuar el tratamiento. Enfoque jerárquico facilita la combinación de múltiples dispositivos para ofrecer un tratamiento eficaz mediante la categorización de la arquitectura de control en dos niveles : el control de bajo nivel y de alto nivel. Los enfoques basados en tareas involucran a la persona en cada tarea individual, y ofrecen la posibilidad de combinarlas en cualquier momento. También es necesario proporcionar un enfoque basado en la interacción con el usuario, para asegurar su participación y lograr así una terapia eficaz. Mediante esta tesis, proponemos un control adaptativo basado en tareas y en función de la interacción persona-ortesis, que se aplica en un esquema de control jerárquico. Este esquema de control se emplea en un robot portátil, con la intención de ser aplicado o acomodado a diferentes patologías, con sus capacidades de adaptación. El modelo de control adaptativo propuesto proporciona una solución integral a través de una única aplicación: adaptación dentro de la marcha y apoyo continúo a través de ejercicios de movilidad en tiempo real. El rendimiento del modelo se ha evaluado en sujetos sanos según un estudio preliminar, y posteriormente también en pacientes parapléjicos. Los resultados en sujetos sanos mostraron un cambio significativo en el patrón de los pares de interacción, elucidando un cambio en la energía y la adaptación al movimiento del usuario. En el caso de los pacientes, la adaptación mostró una mejora significativa en la actuación conjunta (rango de flexión / extensión) y el cambio en pares de interacción. El cambio activo en pares de interacción (positivo a negativo) refleja la participación activa del paciente, lo que también explica el comportamiento adaptativo

Event-based control for sit-to-stand transition using a wearable exoskeleton

Sit-to-stand transition is an essential step in a lower limb rehabilitation therapy, mainly for assisting the patient to transit from wheel chair to the next level of therapy. A mixed stiffness-damping control adaptation is proposed for this task which will help in reaching the final position with a constant velocity. A combination of control model is proposed to ensure the initiation and the final stage of the transition, such as to ensure stability and to maintain the equilibrium. The combined control model helps in reaching the goal position with equal participation from the user. For patient studies, such as with paraplegic patients, a combinational control model with muscle stimulation can be included to provide a complete assistance. The role of muscle stimulation and joint movement assistance is also considered in this control model. Further, final stage of this transition must ensure keeping or helping the user to maintain the upright position.Peer ReviewedPostprint (author's final draft

Adaptive walking assistance based on human-orthosis interaction

An assistive rehabilitation strategy for a lower-limb wearable robot is proposed and evaluated. The control strategy monitors the human-orthosis interaction torques and modifies the orthosis operation mode depending on its evolution with respect to a normal gait pattern. The control algorithm relies on the adaptation of the joints stiffness in function of these interaction torques and to the deviation from the desired trajectory. A walking pattern, an average of recorded gaits, is used as reference input. The human-orthosis interaction torques are used to define the time instant when robot assistance is needed and its degree. The objective of this work is to demonstrate the feasibility of ensuring a dynamic stability by means of an efficient real-time stiffness adaptation for multiple joints and simultaneously maintaining their synchronization. The algorithm has been tested with five healthy subjects showing its efficient behavior in maintaining the equilibrium while walking in presence of external forces. The work is performed as a preliminary study to assist patients suffering from Spinal cord injury and Stroke.Peer ReviewedPostprint (author's final draft

Towards Advanced Robotic Manipulations for Nuclear Decommissioning

Despite enormous remote handling requirements, remarkably very few robots are being used by the nuclear industry. Most of the remote handling tasks are still performed manually, using conventional mechanical master‐slave devices. The few robotic manipulators deployed are directly tele‐operated in rudimentary ways, with almost no autonomy or even a pre‐programmed motion. In addition, majority of these robots are under‐sensored (i.e. with no proprioception), which prevents them to use for automatic tasks. In this context, primarily this chapter discusses the human operator performance in accomplishing heavy‐duty remote handling tasks in hazardous environments such as nuclear decommissioning. Multiple factors are evaluated to analyse the human operators’ performance and workload. Also, direct human tele‐operation is compared against human‐supervised semi‐autonomous control exploiting computer vision. Secondarily, a vision‐guided solution towards enabling advanced control and automating the under‐sensored robots is presented. Maintaining the coherence with real nuclear scenario, the experiments are conducted in the lab environment and results are discussed

Model-free and learning-free grasping by Local Contact Moment matching

This paper addresses the problem of grasping arbitrarily shaped objects, observed as partial point-clouds, without requiring: models of the objects, physics parameters, training data, or other a-priori knowledge. A grasp metric is proposed based on Local Contact Moment (LoCoMo). LoCoMo combines zero-moment shift features, of both hand and object surface patches, to determine local similarity. This metric is then used to search for a set of feasible grasp poses with associated grasp likelihoods. LoCoMo overcomes some limitations of both classical grasp planners and learning-based approaches. Unlike force-closure analysis, LoCoMo does not require knowledge of physical parameters such as friction coefficients, and avoids assumptions about fingertip contacts, instead enabling robust contacts of large areas of hand and object surface. Unlike more recent learning-based approaches, LoCoMo does not require training data, and does not need any prototype grasp configurations to be taught by kinesthetic demonstration. We present results of real-robot experiments grasping 21 different objects, observed by a wrist-mounted depth camera. All objects are grasped successfully when presented to the robot individually. The robot also successfully clears cluttered heaps of objects by sequentially grasping and lifting objects until none remain.</p

Control of an ambulatory exoskeleton with a brain-machine interface for spinal cord injury gait rehabilitation

The closed-loop control of rehabilitative technologies by neural commands has shown a great potential to improve motor recovery in patients suffering from paralysis. Brain-machine interfaces (BMI) can be used as a natural control method for such technologies. BMI provides a continuous association between the brain activity and peripheral stimulation, with the potential to induce plastic changes in the nervous system. Paraplegic patients, and especially the ones with incomplete injuries, constitute a potential target population to be rehabilitated with brain-controlled robotic systems, as they may improve their gait function after the reinforcement of their spared intact neural pathways. This paper proposes a closed-loop BMI system to control an ambulatory exoskeleton-without any weight or balance support-for gait rehabilitation of incomplete spinal cord injury (SCI) patients. The integrated system was validated with three healthy subjects, and its viability in a clinical scenario was tested with four SCI patients. Using a cue-guided paradigm, the electroencephalographic signals of the subjects were used to decode their gait intention and to trigger the movements of the exoskeleton. We designed a protocol with a special emphasis on safety, as patients with poor balance were required to stand and walk. We continuously monitored their fatigue and exertion level, and conducted usability and user-satisfaction tests after the experiments. The results show that, for the three healthy subjects, 84.44 ± 14.56% of the trials were correctly decoded. Three out of four patients performed at least one successful BMI session, with an average performance of 77.6 1 ± 14.72%. The shared control strategy implemented (i.e., the exoskeleton could only move during specific periods of time) was effective in preventing unexpected movements during periods in which patients were asked to relax. On average, 55.22 ± 16.69% and 40.45 ± 16.98% of the trials (for healthy subjects and patients, respectively) would have suffered from unexpected activations (i.e., false positives) without the proposed control strategy. All the patients showed low exertion and fatigue levels during the performance of the experiments. This paper constitutes a proof-of-concept study to validate the feasibility of a BMI to control an ambulatory exoskeleton by patients with incomplete paraplegia (i.e., patients with good prognosis for gait rehabilitation)

Function and differentiation of CD4&quot;+ subsets identified by the monoclonal antibodies WR16 and WR19

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Purification and characterisation of gliadin fractions from wheat flour

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