The Alkaline Mercerization of Wool

The mercerization of a plain-woven wool fabric by treatment with 16, 29, 38, and 44 per cent sodium hydroxide for five minutes at l5°C. has been followed by determination of the weight, nitrogen, sulfur, and breaking strength of the residual fabric

The Alkaline Decomposition of Wool Keratin

The alkaline hydrolysis of wool keratin effected in ten hours at 25°, 40°, and 55°C. has been followed by determination of the weight, nitrogen, sulfur, and wet breaking strength of the residual wool fabric. The decrease in weight, nitrogen, sulfur, and wet breaking strength and the ratio of the sulfur of the hydrolysate to that of the residual wool have been shown to be greater, the greater the concentration of alkali or the greater the temperature. The weight of the residual wool has been shown to be a linear function of the alkali concentration, the nitrogen and sulfur to be functions of the form, y = axb. The ratio of sulfur to nitrogen decreased with increasing concentration of alkali or increasing temperature

Chicora research contribution 236

This survey was done to assess the archaeological significance of the site

Dimerization and Heme Binding Are Conserved in Amphibian and Starfish Homologues of the microRNA Processing Protein DGCR8

Human DiGeorge Critical Region 8 (DGCR8) is an essential microRNA (miRNA) processing factor that is activated via direct interaction with Fe(III) heme. In order for DGCR8 to bind heme, it must dimerize using a dimerization domain embedded within its heme-binding domain (HBD). We previously reported a crystal structure of the dimerization domain from human DGCR8, which demonstrated how dimerization results in the formation of a surface important for association with heme. Here, in an attempt to crystallize the HBD, we search for DGCR8 homologues and show that DGCR8 from Patiria miniata (bat star) also binds heme. The extinction coefficients (ε) of DGCR8-heme complexes are determined; these values are useful for biochemical analyses and allow us to estimate the heme occupancy of DGCR8 proteins. Additionally, we present the crystal structure of the Xenopus laevis dimerization domain. The structure is very similar to that of human DGCR8. Our results indicate that dimerization and heme binding are evolutionarily conserved properties of DGCR8 homologues not only in vertebrates, but also in at least some invertebrates

Fathers Are Parents, Too! Widening the Lens on Parenting for Children’s Development

Why do fathers matter? Recent conceptual and theoretical advances regarding father–child relationships have demonstrated that fathers affect children’s outcomes both directly and indirectly. To attain a complete developmental account of the ecologically rich contexts of child development, in this article, we recommend best practices regarding the conceptualization and assessment of father–child relationships that reflect contemporary family life. We also discuss conceptual and measurement issues pertaining to father–child relationships in different family configurations, including those with resident and nonresident fathers. We conclude with recommendations that can help developmental researchers advance our understanding of fathering, parenting, and children’s development.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/145283/1/cdep12275.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/145283/2/cdep12275_am.pd

Do semantic contextual cues facilitate transfer learning from video in toddlers?

Young children typically demonstrate a transfer deficit, learning less from video than live presentations. Semantically meaningful context has been demonstrated to enhance learning in young children. We examined the effect of a semantically meaningful context on toddlers\u27 imitation performance. Two- and 2.5-year-olds participated in a puzzle imitation task to examine learning from either a live or televised model. The model demonstrated how to assemble a three-piece puzzle to make a fish or a boat, with the puzzle demonstration occurring against a semantically meaningful background context (ocean) or a yellow background (no context). Participants in the video condition performed significantly worse than participants in the live condition, demonstrating the typical transfer deficit effect. While the context helped improve overall levels of imitation, especially for the boat puzzle, only individual differences in the ability to self-generate a stimulus label were associated with a reduction in the transfer deficit

Evaluating CollaboRATE in a Clinical Setting: Analysis of Mode Effects on Scores, Response Rates and Costs of Data Collection

Shared decision-making (SDM) has become a policy priority, yet its implementation is not routinely assessed. To address this gap we tested the delivery of CollaboRATE, a 3-item patient reported experience measure of SDM, via multiple survey modes.To assess CollaboRATE response rates and respondent characteristics across different modes of administration, impact of mode and patient characteristics on SDM performance and cost of administration per response in a real-world primary care practice.Observational study design, with repeated assessment of SDM performance using CollaboRATE in a primary care clinic over 15 months of data collection. Different modes of administration were introduced sequentially including paper, patient portal, interactive voice response (IVR) call, text message and tablet computer.Consecutive patients ≥18 years, or parents/guardians of patients \u3c18 years, visiting participating primary care clinicians.CollaboRATE assesses three core SDM tasks: (1) explanation about health issues, (2) elicitation of patient preferences and (3) integration of patient preferences into decisions. Responses to each item range from 0 (no effort was made) to 9 (every effort was made). CollaboRATE scores are calculated as the proportion of participants who report a score of nine on each of the three CollaboRATE questions.Scores were sensitive to mode effects: the paper mode had the highest average score (81%) and IVR had the lowest (61%). However, relative clinician performance rankings were stable across the different data collection modes used. Tablet computers administered by research staff had the highest response rate (41%), although this approach was costly. Clinic staff giving paper surveys to patients as they left the clinic had the lowest response rate (12%).CollaboRATE can be introduced using multiple modes of survey delivery while producing consistent clinician rankings. This may allow routine assessment and benchmarking of clinician and clinic SDM performance

Climatic controls on the equilibrium-line altitudes of Scandinavian cirque glaciers

The equilibrium-line altitudes (ELAs) of reconstructed palaeoglaciers have been widely used to assess palaeoclimatic conditions, yet this concept has rarely been tested using modern glaciers. To address this shortcoming, correlations between the ELAs of 513 modern cirque glaciers and present day climatic and topographic variables across Scandinavia, as well as regional trends in ELA and climate, are analysed. ELAs are calculated using the Area-Altitude-Balance-Ratio method, with a ratio of 1.5 ± 0.4. Results indicate that glacier ELAs are strongly correlated with distance from the coast. This reflects the present-day precipitation pattern of the region (characterised by high precipitation near the sea) and demonstrates a climate dominated by a maritime-continental transition. Temperature explains differences in glacier ELA regional trends as well as ELA changes with latitude. Following standard meteorological convention, Scandinavia is divided into two macro-climate regions and analyses are run within the macro-regions as well as the complete dataset. The strength of correlations between ELA and precipitation increases when the study is divided into northern and southern macro-regions. These results test long held assumptions about relationships between climate and cirque glacier ELA, which is of particular relevance to palaeoclimatic studies based on the reconstruction of former cirque glaciers