327 research outputs found

    A thematic analysis exploring the psychological well-being of adults born with esophageal atresia

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    Background: Living with a rare and chronic health condition can have a significant impact on psychological well-being and mental health. There is a growing understanding that Esophageal Atresia (EA), a rare birth defect often accompanied by a Trachea-Esophageal Fistula (TEF), is a complex health condition that requires lifelong medical attention beyond pediatric care into adulthood. Given the reciprocal relationship between one's physical and psychological well-being, the aim of this study was to develop a better understanding of the mental health of adults born with EA/TEF. Methods: An international online survey was designed and disseminated in collaboration with an EA/TEF patient charity. The qualitative data was analyzed using a reflexive and inductive Thematic Analysis to explore the research question “How can being born with EA/TEF affect psychological well-being in adulthood?” Results: A total of 92 adults born with EA/TEF completed the online survey from 11 different counties. Five themes were generated during the analysis: ‘Negative Experience with Healthcare Professionals’, ‘The Perception of Surgical Scars’, ‘The Psychosocial Consequences of Dysphagia’, ‘The Legacy of Medical Trauma’, and ‘Resilience in the Face of Adversity’. Conclusion: The results indicated that adults born with EA/TEF might face emotional challenges that can negatively affect their psychological well-being and mental health. It was also found that some adults born with EA/TEF demonstrate resilience through positive reappraisal of adverse experiences. The current study suggests that a multidisciplinary approach to the care of adults born with EA/TEF is necessary and directions for future research are discussed.</p

    Traceability Approaches for Marine Genetic Resources Under the Proposed Ocean (BBNJ) Treaty

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    FUNDING The open access fee was funded by the Griffith University Queensland. ACKNOWLEDGMENTS We wish to thank Aurélie Lécolier and Sylvia Colliec Jouault at IFREMER for information on Deepsane; Marjo Vierros for providing information hydrothermal vent patents from ABNJ, and Charles Lawson for providing comments on the manuscript. The cartoon figures used in Figures 1, 6 are from the Noun Project (DNA by Vectors Point, coral by Nook Fulloption, liquid by Smalllike, database by Flatart, third party by Priyanka, drug by Adindar, label by AB Designs, certificate by Libertetstudio, aeroplane by Deepz, car by Adrien Coquet, dolly by Vectorstall, box by IconMark, factory by Iconsphere, and barcode by Adned Kadri).Peer reviewedPublisher PD

    Praziquantel coverage in schools and communities targeted for the elimination of urogenital schistosomiasis in Zanzibar: a cross-sectional survey

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    © 2015 Knopp et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. The attached file is the published version of the article

    Abyssal fauna of polymetallic nodule exploration areas, eastern Clarion-Clipperton Zone, central Pacific Ocean: Annelida: Spionidae and Poecilochaetidae

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    This paper represents a continuation of taxonomic publications on the benthic fauna of polymetallic nodule fields in the eastern Clarion-Clipperton Zone (CCZ) using material collected during baseline environmental survey work targeting two exploration contract areas (“UK-1” and “OMS”) and one Area of Particular Environmental Interest, “APEI-6.” Families Poecilochaetidae Hannerz, 1956 and Spionidae Grube, 1850 of the annelid suborder Spioniformia were studied here. Taxonomic data are presented for 25 species from 98 records as identified by a combination of morphological and genetic approaches. Although sub-optimal morphological condition can prevent new species being formally described, it is essential that morphological, molecular, and voucher data are made available for future surveys. Descriptions of two new species—Poecilochaetus brenkei sp. nov. and Laonice shulseae sp. nov.—increase the number of formally described new annelid species from the areas targeted in this study to 15 and CCZ-wide to 46. We also discuss the commonly reported “cosmopolitan” deep-sea spionid Aurospio dibranchiata Maciolek, 1981, which we show represents several genetically distinct species (three of these from CCZ area alone) but without reliable morphological characters to separate them. Molecular data provide evidence that 15 out of 25 species reported here have a wide distribution within the eastern CCZ and that Aurospio sp. “NHM_2186” and the known species Prionospio amarsupiata Neal & Altamira in Paterson et al. 2016 may be cosmopolitan. Lastly, the molecular data provide insights into relationships within Spioniformia, suggesting that both Poecilochaetidae and Trochochaetidae belong within Spionidae.publishedVersio

    Hg-supported phospholipid monolayer as rapid screening device for low molecular weight narcotic compounds in water

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    This study positions the fabricated Pt/Hg-supported phospholipid sensor element in the context of more conventional biomembrane-based screening platforms. The technology has been used together with immobilised artificial membrane (IAM) chromatography and COSMOmic simulation methods to screen the interaction of a series of low molecular weight narcotic organic compounds in water with phosphatidylcholine (PC) membranes. For these chemicals it is shown that toxicity to aquatic species is related to compound hydrophobicity which is associated with compound accumulation in the phospholipid membrane as modelled by IAM chromatography measurements and COSMOmic simulations. In contrast, the Hg-supported dioleoyl phosphatidylcholine (DOPC) sensor element records membrane damage/modification which is indirectly related to general toxicity and directly related to compound structure. Electrochemical limit of detection (LoD) values depend on molecular structure and range from 20â€ŻÎŒmolL−1 for substituted phenols to 23 mmolL−1 for aliphatics. Rapid cyclic voltammetry (RCV) “fingerprints” showed that the major structural classes of compounds: alkyl/chlorobenzenes, substituted phenols, quaternary ammonium compounds and neutral amines interacted distinctively with the DOPC on Hg and that these observations correlated with and supported those predicted by the COSMOmic simulations of the compound/DMPC association. In addition, the compatibility of the electrochemical and COSMOmic methods validates the electrochemical device as a meaningful high throughput technology to screen compounds in water and report on the mechanistic details of their interaction with phospholipid layers

    Abyssal fauna of the UK-1 polymetallic nodule exploration area, Clarion-Clipperton Zone, central Pacific Ocean: Mollusca

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    The file attached is the Published/publisher’s pdf version of the article. This is an OpenAccess article.Copyright Helena Wiklund et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
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