348 research outputs found
Entropy and information in neural spike trains: Progress on the sampling problem
The major problem in information theoretic analysis of neural responses and
other biological data is the reliable estimation of entropy--like quantities
from small samples. We apply a recently introduced Bayesian entropy estimator
to synthetic data inspired by experiments, and to real experimental spike
trains. The estimator performs admirably even very deep in the undersampled
regime, where other techniques fail. This opens new possibilities for the
information theoretic analysis of experiments, and may be of general interest
as an example of learning from limited data.Comment: 7 pages, 4 figures; referee suggested changes, accepted versio
Post-AGB stars with hot circumstellar dust: binarity of the low-amplitude pulsators
While the first binary post-AGB stars were serendipitously discovered, the
distinct characteristics of their Spectral Energy Distribution (SED) allowed us
to launch a more systematic search for binaries. We selected post-AGB objects
which show a broad dust excess often starting already at H or K, pointing to
the presence of a gravitationally bound dusty disc in the system. We started a
very extensive multi-wavelength study of those systems and here we report on
our radial velocity and photometric monitoring results for six stars of early F
type, which are pulsators of small amplitude. To determine the radial velocity
of low signal-to-noise time-series, we constructed dedicated auto-correlation
masks. The radial velocity variations were subjected to detailed analysis to
differentiate between pulsational variability and variability due to orbital
motion. Finally orbital minimalisation was performed to constrain the orbital
elements. All of the six objects are binaries, with orbital periods ranging
from 120 to 1800 days. Five systems have non-circular orbits. The mass
functions range from 0.004 to 0.57 solar mass and the companions are likely
unevolved objects of (very) low initial mass. We argue that these binaries must
have been subject to severe binary interaction when the primary was a cool
supergiant. Although the origin of the circumstellar disc is not well
understood, the disc is generally believed to be formed during this strong
interaction phase. The eccentric orbits of these highly evolved objects remain
poorly understood. With the measured orbits and mass functions we conclude that
the circumbinary discs seem to have a major impact on the evolution of a
significant fraction of binary systems.Comment: 13 pages, 15 figures, accepted for Astronomy and Astrophysic
Resolving the compact dusty discs around binary post-AGB stars using N-band interferometry
We present the first mid-IR long baseline interferometric observations of the
circumstellar matter around binary post-AGB stars. Two objects, SX Cen and HD
52961, were observed using the VLTI/MIDI instrument during Science
Demonstration Time. Both objects are known binaries for which a stable
circumbinary disc is proposed to explain the SED characteristics. This is
corroborated by our N-band spectrum showing a crystallinity fraction of more
than 50 % for both objects, pointing to a stable environment where dust
processing can occur. Surprisingly, the dust surrounding SX Cen is not resolved
in the interferometric observations providing an upper limit of 11 mas (or 18
AU at the distance of this object) on the diameter of the dust emission. This
confirms the very compact nature of its circumstellar environment. The dust
emission around HD 52961 originates from a very small but resolved region,
estimated to be ~ 35 mas at 8 micron and ~ 55 mas at 13 micron. These results
confirm the disc interpretation of the SED of both stars. In HD 52961, the dust
is not homogeneous in its chemical composition: the crystallinity is clearly
concentrated in the hotter inner region. Whether this is a result of the
formation process of the disc, or due to annealing during the long storage time
in the disc is not clear.Comment: 12 pages, 10 figures, accepted for publication in A &
Beyond the call of duty: Why customers contribute to firm-hosted commercial online communities
Firm-hosted commercial online communities, in which customers interact to solve each other's service problems, represent a fascinating context to study the motivations of collective action in the form of knowledge contribution to the community. We extend a model of social capital based on Wasko and Faraj (2005) to incorporate and contrast the direct impact of commitment to both the online community and the host firm, as well as reciprocity, on quality and quantity of knowledge contribution. In addition, we examine the moderating influence of three individual attributes that are particularly relevant to the firm-hosted community context: perceived informational value, sportsmanship, and online interaction propensity. We empirically test our framework using self-reported and objective data from 203 members of a firm-hosted technical support community. In addition to several interesting moderating effects, we find that a customer's online interaction propensity, commitment to the community, and the informational value s/he perceives in the community are the strongest drivers of knowledge contribution
Effect of sampling effort and sampling frequency on the composition of the planktonic crustacean assemblage: a case study of the river Danube
Although numerous studies have focused
on the seasonal dynamics of riverine zooplankton,
little is known about its short-term
variation. In order to examine the effects of sampling
frequency and sampling effort, microcrustacean
samples were collected at daily intervals
between 13 June and 21 July of 2007 in a parapotamal
side arm of the river Danube, Hungary.
Samples were also taken at biweekly intervals
from November 2006 to May 2008. After presenting
the community dynamics, the effect of
sampling effort was evaluated with two different
methods; the minimal sample size was also estimated.
We introduced a single index (potential
dynamic information loss; to determine the potential
loss of information when sampling frequency
is reduced. The formula was calculated for the total abundance, densities of the dominant taxa, adult/larva ratios of copepods and for two different diversity measures. Results suggest that abundances may experience notable fluctuations even within 1 week, as do diversities and adult/larva ratios
Imaging the nanoscale organization of peptidoglycan in living Lactococcus lactis cells
Peptidoglycans provide bacterial cell walls with
mechanical strength. The spatial organization of peptidoglycan has previously been difficult
to study. Here, atomic force microscopy, together with cells carrying mutations in cell-wall
polysaccharides, has allowed an in-depth study of these molecules
Analysis of the Peptidoglycan Hydrolase Complement of Lactobacillus casei and Characterization of the Major γ-D-Glutamyl-L-Lysyl-Endopeptidase
Peptidoglycan (PG) is the major component of Gram positive bacteria cell wall and is essential for bacterial integrity and shape. Bacteria synthesize PG hydrolases (PGHs) which are able to cleave bonds in their own PG and play major roles in PG remodelling required for bacterial growth and division. Our aim was to identify the main PGHs in Lactobacillus casei BL23, a lactic acid bacterium with probiotic properties
Consumer Complaints and Company Market Value
Consumer complaints affect company market value and common sense suggests that a negative impact is
expected. However, do complaints always negatively impact company market value? We hypothesize in this
study that complaints may have a non-linear effect on market value. Positive (e.g. avoiding high costs to solve
complaints) and negative (e.g. speedy and intense diffusion) tradeoffs may occur given the level of complaints.
To test our non-linear hypothesis, a panel data was collected from cell phone service providers from 2005 to
2013. The results supported our tradeoff rationale. Low levels of complaints allow for companies to increase
market value, while high levels of complaints cause increasing harm to market value. The sample, model and
period considered in this study, indicates a level of 0.49 complaints per thousand consumers as the threshold for
a shift in tradeoffs. The effects on market value become increasingly negative when trying to make reductions to
move below this level, due to negative tradeoffs
The same ELA class II risk factors confer equine insect bite hypersensitivity in two distinct populations
Insect bite hypersensitivity (IBH) is a chronic allergic dermatitis common in horses. Affected horses mainly react against antigens present in the saliva from the biting midges, Culicoides ssp, and occasionally black flies, Simulium ssp. Because of this insect dependency, the disease is clearly seasonal and prevalence varies between geographical locations. For two distinct horse breeds, we genotyped four microsatellite markers positioned within the MHC class II region and sequenced the highly polymorphic exons two from DRA and DRB3, respectively. Initially, 94 IBH-affected and 93 unaffected Swedish born Icelandic horses were tested for genetic association. These horses had previously been genotyped on the Illumina Equine SNP50 BeadChip, which made it possible to ensure that our study did not suffer from the effects of stratification. The second population consisted of 106 unaffected and 80 IBH-affected Exmoor ponies. We show that variants in the MHC class II region are associated with disease susceptibility (praw = 2.34 × 10−5), with the same allele (COR112:274) associated in two separate populations. In addition, we combined microsatellite and sequencing data in order to investigate the pattern of homozygosity and show that homozygosity across the entire MHC class II region is associated with a higher risk of developing IBH (p = 0.0013). To our knowledge this is the first time in any atopic dermatitis suffering species, including man, where the same risk allele has been identified in two distinct populations
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