206 research outputs found
Three types of shopping precincts. Three different ways to influence the public sphere of neighborhoods
Indexación: Scopus.Considerando que en la teorÃa urbana el mercado y
los espacios públicos están históricamente vinculados,
este artÃculo analiza un mercado, una galerÃa
comercial y un centro comercial (mall). El fin es ilustrar
los factores que son determinantes para que en
Santiago de Chile estas tipologÃas de comercio adquieran
carácter público y puedan contribuir a la esfera
pública de la ciudad, al menos dentro de las limitaciones
que se derivan de su condición privada. Hasta
ahora el debate ha reflexionado extensivamente sobre
estas tres tipologÃas, sin embargo, existen aún pocos
estudios que miran la vida pública que tiene lugar en estas diferentes tipologÃas de manera paralela, considerando
que hoy todas ellas están presentes simultáneamente
en la ciudad y se disputan su espacio en
ella. Esta investigación describe caracterÃsticas fÃsicoespaciales
y de administración de estos tres casos para
aportar a las polÃticas públicas y el diseño urbano. Se
estudia el comercio en relación a la accesibilidad a nivel
metropolitano y en cuanto a los diferentes tipos de
comercio, que pretenden atraer un público diverso y
promueven el carácter público de los espacios.According to urban theory, commerce and public
spaces are historically related to each other.
Based on this premise, this paper analyzes a
market, a shopping center and a mall. The goal
of this research is to identify the key factors that
turn these shopping precincts into public spaces
and contribute to the public sphere in Santiago,
Chile, at least within the context of the limitations
associated with their private nature. To date,
these three typologies have been the focus of
intense debate. However, there are few studies of
the public life that takes place in these spaces, especially when considering that they coexist
simultaneously in the city, claiming a space within
it. This research describes the physical-spatial
and administrative characteristics of these three
cases in order to contribute to the strengthening
of public policies in urban design. Likewise,
commerce is studied in relation to accessibility
patterns at metropolitan level and the types of
markets that aim to attract different users and
promote the public nature of these spaces.https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0718-83582018000100089&lng=en&nrm=iso&tlng=e
Development of coordination and muscular fitness in children and adolescents with parent-reported ADHD in the German longitudinal MoMo Study
This study examined the development of muscular fitness and coordination in children and adolescents with and without attention deficit hyperactivity disorder (ADHD) over a period of 11 years. Data was collected in three measurement waves as part of the longitudinal, representative Motorik-Modul (MoMo) study in Germany (2003–2006, 2009–2012, 2014–2017). The overall sample comprised 2988 participants (253 with ADHD, 65% males; 2735 non-ADHD, 47% males; mean age 9 years). Structural equation modeling was conducted, and the estimated models had a good fit. No differences in muscular fitness were observed between participants with and without ADHD. Participants with ADHD had a lower coordinative performance at first measurement than those without ADHD. The difference in coordinative performance persisted throughout the study period
Structural neural networks subserving oculomotor function in first-episode schizophrenia
BACKGROUND: Smooth pursuit and antisaccade abnormalities are well documented in schizophrenia, but their neuropathological correlates remain unclear.
METHODS: In this study, we used statistical parametric mapping to investigate the relationship between oculomotor abnormalities and brain structure in a sample of first-episode schizophrenia patients (n = 27). In addition to conventional volumetric magnetic resonance imaging, we also used magnetization transfer ratio, a technique that allows more precise tissue characterization.
RESULTS: We found that smooth pursuit abnormalities were associated with reduced magnetization transfer ratio in several regions, predominantly in the right prefrontal cortex. Antisaccade errors correlated with gray matter volume in the right medial superior frontal cortex as measured by conventional magnetic resonance imaging but not with magnetization transfer ratio.
CONCLUSIONS: These preliminary results demonstrate that specific structural abnormalities are associated with abnormal eye movements in schizophrenia
Helium-Induced Early Preconditioning and Postconditioning Are Abolished in Obese Zucker Rats in Vivo
The challenge of comprehensively mapping children's health in a nation-wide health survey: Design of the German KiGGS-Study
<p>Abstract</p> <p>Background</p> <p>From May 2003 to May 2006, the Robert Koch Institute conducted the German Health Interview and Examination Survey for Children and Adolescents (KiGGS). Aim of this first nationwide interview and examination survey was to collect comprehensive data on the health status of children and adolescents aged 0 to 17 years.</p> <p>Methods/Design</p> <p>Participants were enrolled in two steps: first, 167 study locations (sample points) were chosen; second, subjects were randomly selected from the official registers of local residents. The survey involved questionnaires filled in by parents and parallel questionnaires for children aged 11 years and older, physical examinations and tests, and a computer assisted personal interview performed by study physicians. A wide range of blood and urine testing was carried out at central laboratories. A total of 17 641 children and adolescents were surveyed – 8985 boys and 8656 girls. The proportion of sample neutral drop-outs was 5.3%. The response rate was 66.6%.</p> <p>Discussion</p> <p>The response rate showed little variation between age groups and sexes, but marked variation between resident aliens and Germans, between inhabitants of cities with a population of 100 000 or more and sample points with fewer inhabitants, as well as between the old West German states and the former East German states. By analysing the short non-responder questionnaires it was proven that the collected data give comprehensive and nationally representative evidence on the health status of children and adolescents aged 0 to 17 years.</p
Vestibular Facilitation of Optic Flow Parsing
Simultaneous object motion and self-motion give rise to complex patterns of retinal image motion. In order to estimate object motion accurately, the brain must parse this complex retinal motion into self-motion and object motion components. Although this computational problem can be solved, in principle, through purely visual mechanisms, extra-retinal information that arises from the vestibular system during self-motion may also play an important role. Here we investigate whether combining vestibular and visual self-motion information improves the precision of object motion estimates. Subjects were asked to discriminate the direction of object motion in the presence of simultaneous self-motion, depicted either by visual cues alone (i.e. optic flow) or by combined visual/vestibular stimuli. We report a small but significant improvement in object motion discrimination thresholds with the addition of vestibular cues. This improvement was greatest for eccentric heading directions and negligible for forward movement, a finding that could reflect increased relative reliability of vestibular versus visual cues for eccentric heading directions. Overall, these results are consistent with the hypothesis that vestibular inputs can help parse retinal image motion into self-motion and object motion components
Motor Properties of Peripersonal Space in Humans
Background: A stimulus approaching the body requires fast processing and appropriate motor reactions. In monkeys, fronto-parietal networks are involved both in integrating multisensory information within a limited space surrounding the body (i.e. peripersonal space, PPS) and in action planning and execution, suggesting an overlap between sensory representations of space and motor representations of action. In the present study we investigate whether these overlapping representations also exist in the human brain. Methodology/Principal Findings: We recorded from hand muscles motor-evoked potentials (MEPs) induced by single-pulse of transcranial magnetic stimulation (TMS) after presenting an auditory stimulus either near the hand or in far space. MEPs recorded 50 ms after the near-sound onset were enhanced compared to MEPs evoked after far sounds. This near-far modulation faded at longer inter-stimulus intervals, and reversed completely for MEPs recorded 300 ms after the sound onset. At that time point, higher motor excitability was associated with far sounds. Such auditory modulation of hand motor representation was specific to a hand-centred, and not a body-centred reference frame. Conclusions/Significance: This pattern of corticospinal modulation highlights the relation between space and time in the PPS representation: an early facilitation for near stimuli may reflect immediate motor preparation, whereas, at later time intervals, motor preparation relates to distant stimuli potentially approaching the body
Effect of remote ischemic conditioning on atrial fibrillation and outcome after coronary artery bypass grafting (RICO-trial)
Background: Pre- and postconditioning describe mechanisms whereby short ischemic periods protect an organ against a longer period of ischemia. Interestingly, short ischemic periods of a limb, in itself harmless, may increase the ischemia tolerance of remote organs, e.g. the heart (remote conditioning, RC). Although several studies have shown reduced biomarker release by RC, a reduction of complications and improvement of patient outcome still has to be demonstrated. Atrial fibrillation (AF) is one of the most common complications after coronary artery bypass graft surgery (CABG), affecting 27-46% of patients. It is associated with increased mortality, adverse cardiovascular events, and prolonged in-hospital stay. We hypothesize that remote ischemic pre- and/or post-conditioning reduce the incidence of AF following CABG, and improve patient outcome.Methods/design: This study is a randomized, controlled, patient and investigator blinded multicenter trial. Elective CABG patients are randomized to one of the following four groups: 1) control, 2) remote ischemic preconditioning, 3) remote ischemic postconditioning, or 4) remote ischemic pre- and postconditioning. Remote conditio
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