Present and Future of Parkinson’s Disease in Spain: PARKINSON-2030 Delphi Project

Parkinson's disease (PD) is a chronic progressive and irreversible disease and the second most common neurodegenerative disease worldwide. In Spain, it affects around 120.000-150.000 individuals, and its prevalence is estimated to increase in the future. PD has a great impact on patients' and caregivers' lives and also entails a substantial socioeconomic burden. The aim of the present study was to examine the current situation and the 10-year PD forecast for Spain in order to optimize and design future management strategies. This study was performed using the modified Delphi method to try to obtain a consensus among a panel of movement disorders experts. According to the panel, future PD management will improve diagnostic capacity and follow-up, it will include multidisciplinary teams, and innovative treatments will be developed. The expansion of new technologies and studies on biomarkers will have an impact on future PD management, leading to more accurate diagnoses, prognoses, and individualized therapies. However, the socio-economic impact of the disease will continue to be significant by 2030, especially for patients in advanced stages. This study highlighted the unmet needs in diagnosis and treatment and how crucial it is to establish recommendations for future diagnostic and therapeutic management of PD

COVID-19 outbreaks in a transmission control scenario: challenges posed by social and leisure activities, and for workers in vulnerable conditions, Spain, early summer 2020

Severe acute respiratory syndrome coronavirus 2 community-wide transmission declined in Spain by early May 2020, being replaced by outbreaks and sporadic cases. From mid-June to 2 August, excluding single household outbreaks, 673 outbreaks were notified nationally, 551 active (>6,200 cases) at the time. More than half of these outbreaks and cases coincided with: (i) social (family/friends’ gatherings or leisure venues) and (ii) occupational (mainly involving workers in vulnerable conditions) settings. Control measures were accordingly applied

High Proportion of Male Faeces in Jaguar Populations

Faeces provide relevant biological information which includes, with the application of genetic techniques, the sex and identity of individuals that defecated, thus providing potentially useful data on the behaviour and ecology of individuals, as well as the dynamics and structure of populations. This paper presents estimates of the sex ratio of different felid species (jaguar, Panthera onca; puma, Puma concolor; and ocelot/margay, Leopardus pardalis/Leopardus wiedi) as observed in field collected faeces, and proposes several hypotheses that could explain the strikingly high proportion of faeces from male jaguars. The proportion of male and female faeces was estimated using a non-invasive faecal sampling method in 14 study areas in Mexico and Brazil. Faecal samples were genetically analysed to identify the species, the sex and the individual (the latter only for samples identified as belonging to jaguars). Considering the three species, 72.6% of faeces (n = 493) were from males; however, there were significant differences among them, with the proportion from males being higher for jaguars than for pumas and ocelots/margays. A male-bias was consistently observed in all study areas for jaguar faeces, but not for the other species. For jaguars the trend was the same when considering the number of individuals identified (n = 68), with an average of 4.2±0.56 faeces per male and 2.0±0.36 per female. The observed faecal marking patterns might be related to the behaviour of female jaguars directed toward protecting litters from males, and in both male and female pumas, to prevent interspecific aggressions from male jaguars. The hypothesis that there are effectively more males than females in jaguar populations cannot be discarded, which could be due to the fact that females are territorial and males are not, or a tendency for males to disperse into suboptimal areas for the species. © 2012 Palomares et al

Iberian acid peatlands: types, origin and general trends of development.

The authors thank all researchers who have devoted effort to studying the Iberian peatlands. We are grateful to Christine Francis, native translator, for reviewing and correcting linguistic aspects of this manuscript. Our research has been made possible by the following project grants: INCITE09-200-019-PR (Xunta de Galicia Government); DESIRÈHAR2013-43701-P (Spanish Ministry of Economy and Competitiveness); and Relictflora-P11-RNM7033 (Excellence Research Projects Program from the Andalusian Government)

Present and future of parkinson's disease in Spain : Parkinson-2030 delphi project

Altres ajuts: Zambon S.A.U.Parkinson's disease (PD) is a chronic progressive and irreversible disease and the second most common neurodegenerative disease worldwide. In Spain, it affects around 120.000-150.000 individuals, and its prevalence is estimated to increase in the future. PD has a great impact on pa-tients' and caregivers' lives and also entails a substantial socioeconomic burden. The aim of the present study was to examine the current situation and the 10-year PD forecast for Spain in order to optimize and design future management strategies. This study was performed using the modified Delphi method to try to obtain a consensus among a panel of movement disorders experts. Accord-ing to the panel, future PD management will improve diagnostic capacity and follow-up, it will include multidisciplinary teams, and innovative treatments will be developed. The expansion of new technologies and studies on biomarkers will have an impact on future PD management, leading to more accurate diagnoses, prognoses, and individualized therapies. However, the socio-economic impact of the disease will continue to be significant by 2030, especially for patients in advanced stages. This study highlighted the unmet needs in diagnosis and treatment and how crucial it is to establish recommendations for future diagnostic and therapeutic management of PD

An oasis in the desert:The potential of water sources as camera trap sites in arid environments for surveying a carnivore guild

Discussions regarding the importance of accounting for detection probability have long been present in ecological literature. Various studies have demonstrated the influence of survey design on detection probabilities, and whilst the placement of camera traps along roads is a commonly used survey design, it has shown to be biased towards certain species. In arid environments, water sources have the potential to be efficient sites for camera trap placement. We compared the influence of a water source camera trap survey design on the detection probabilities of a guild of seven carnivore species, in comparison detection probabilities from camera traps along roads, on arid, commercial farmland in southern Namibia. Results showed detection probabilities for all species to be higher at water, with the water source design producing shorter latencies of detections and higher naive occupancy estimates for most species. However, for species with unique markings, the water source design produced lower proportions of images suitable for individual identification. As detection probabilities of all species were influenced in a positive manner, we suggest placing camera traps at water sources in arid environments to be an effective survey design. However, for surveys requiring individual identification, placing camera traps along roads may be more suitable.Nedbank Go Green Fund Namibia, Namdeb Diamond Corporation and Royal Holloway, University of London.http://www.elsevier.com/locate/jaridenv2017-01-31hb2016Centre for Wildlife Managemen

Triplet excited state behavior of naphthalene-based pseudopeptides in the presence of energy donors

In this work, the triplet state behavior of naphthalene-based pseudopeptides with amide-based macrocyclic or lateral chain substructures has been investigated in the presence of benzophenone and/or biphenyl, as suitable energy donating chromophores. Their behavior has been compared with that of 1,4-dimethylnaphthalene as model compound.,,In all the cases,. the triplet-triplet absorption of naphthalene is detected by transient absorption spectroscopy, upon selective excitation of benzophenone at 355 nm. The kinetics of formation and decay of this species is markedly slower in the pseudopeptides, due to retardation of triplet-triplet energy transfer and exciplex formation. Finally, the delayed fluorescence detected in the model naphthalene is absent in the pseudopeptides. The concept can, in principle, be exploited for the study of excited state interactions. in supramolecular systemsFinancial support from the MICINN (Grants CTQ-2010-14882, CTQ2009-14366-C02-01 and FPI contract to P.B.), the Generalitat Valenciana (Prometeo 2008/090), the UPV (PAID 05-11 Program, ref 2766), and Fundacio Caixa Castello-UJI (P1 1B-2009-59) is gratefully acknowledged.Bonancía Roca, P.; Vigara, L.; Galindo, F.; Luis, SV.; Jiménez Molero, MC.; Miranda Alonso, MÁ. (2012). Triplet excited state behavior of naphthalene-based pseudopeptides in the presence of energy donors. Journal of Physical Chemistry B. 116(33):9957-9962. https://doi.org/10.1021/jp304883uS995799621163