11 research outputs found

    Benthic-pelagic coupling in the Greenland-Norwegian Sea and its effect on the geological record

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    The sedimentation pattern of organic material in the Greenland-Norwegian Sea is reflected in the surface sediments, although less than 0.5% of the organic matter is buried in the sediment. Maximum fluxes and benthic responses are observed during June and/or August/September, following the pattern of export production in the pelagial zone. The annual remineralization rate on the Vøring Plateau is 3.0 g C m−2 a −1 Freshly settled phytodetritus, as detected by chlorophyll measurements, is rapidly mixed into the sediment and decomposed. It stimulates the activity of benthic organisms, especially foraminifera. The mixing coefficient for this material is D b=0.2 cm2 d−1, which is two to three orders of magnitude higher than that estimated from radiotracer methods. The effect on the geological record, however, is likely to be small. Chlorophyll-containing particles are at first very evenly distributed on the seafloor. After partial decomposition and resuspension, a secondary redistribution of particles occurs which can result in the formation of a high accumulation area, with an up to 80-fold increase in the sedimentation rate by lateral advection. This is mainly due to physical processes, because biodeposition mediated by benthic animals increases sedimentation by only a factor of two or three

    Glossaire illustré sur les formes d’altération de la pierre

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    The ICOMOS International Scientific Committee for Stone (ISCS) is providing a forum for the interchange of experience, ideas, and knowledge in the field of stone conservation. ISCS aims at facilitating the publication, dissemination and presentation of state of the art reviews on pre-identified issues. Simplification and demystification of scientific information for practitioners are also part of the main goals of the group. In studies on stone deterioration and conservation, terminological confusions lead to major communication problems between scientists, conservators and practitioners. In this context, it is of primary importance to set up a common language; if degradation patterns can be shown, named and described, then they can be recognised and compared with similar ones in a more accurate way in further investigations. The ISCS glossary constitutes an important tool for scientific discussions on decay phenomena and processes. It is also an excellent basis for tutorials on stone deterioration. It is based on the careful examination of pre-existing glossaries of English terms. It does not aim at replacing these glossaries, often set up originally in a language other than English, and for most of them done to a high standard. As President of ICOMOS I would like to congratulate the International Scientific Committee for Stone and its President Véronique Verges-Belmin for the results of years of research presented in this publication. Stone conservation is a crucial topic in monument conservation and many of our National Committees all over the world hope for advice and help from the specialists familiar with traditional and modern methods of conservation. The Illustrated Glossary on Stone Deterioration Patterns offers a wide range of suggestions and practical advice. Probably, after the English-French version becomes available the Glossary will also be translated into other languages. In view of the accelerating decay of our stone monuments worldwide this is an exemplary contribution which will promote the international cooperation so important in this field.peer-reviewe

    Drug treatment is superior to allografting as first-line therapy in chronic myeloid leukemia

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    Early allogeneic hematopoietic stem cell transplantation (HSCT) has been proposed as primary treatment modality for patients with chronic myeloid leukemia (CML). This concept has been challenged by transplantation mortality and improved drug therapy. In a randomized study, primary HSCT and best available drug treatment (IFN based) were compared in newly diagnosed chronic phase CML patients. Assignment to treatment strategy was by genetic randomization according to availability of a matched related donor. Evaluation followed the intention-to-treat principle. Six hundred and twenty one patients with chronic phase CML were stratified for eligibility for HSCT. Three hundred and fifty four patients (62% male; median age, 40 years; range, 11-59 years) were eligible and randomized. One hundred and thirty five patients (38%) had a matched related donor, of whom 123 (91%) received a transplant within a median of 10 months (range, 2-106 months) from diagnosis. Two hundred and nineteen patients (62%) had no related donor and received best available drug treatment. With an observation time up to 11.2 years (median, 8.9 years), survival was superior for patients with drug treatment (P = .049), superiority being most pronounced in low-risk patients (P = .032). The general recommendation of HSCT as first-line treatment option in chronic phase CML can no longer be maintained. It should be replaced by a trial with modern drug treatment first
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