8 research outputs found
Effect of Gravel Size and Weir Height on Flow Properties of Gabions
لقد تم دراست العلاقة بين عمق الماء المتجمع امام السداد الحجرية والتصريف القادم من اعالي المجاري المائية في قناة مختبرية. حيث تم دراسة السطح الحر للماء في حالة التدفق الانتقالي وفي حالة الفيضان فوقه. تضمنت الدراسة تأثير ارتفاع جسم السداد الحجرية وخشونة المواد المستخدمه في الانشاء على عمق تدفق المنبع عن طريق اختبار أربعة ارتفاعات مختلفة من الهدارات وأربعة أحجام مختلفة من الحصى. أظهر تحليل النتائج المختبرية أن الانخفاض النسبي في عمق الماء المتجمع امام الهدارات يتراوح ما بين 38٪ و17٪ لنوع الجريان " التدفق خلال " عندما يزداد كل من خشونة المادة والتصريف، وفي نظام "التدفق الانتقالي"، تؤدي زيادة خشونة المواد والتصريف إلى انخفاض متوسط في عمق التدفق النسبي بين 7.6٪ و4.4٪ لارتفاع الهدارات الحجرية 15 سم و30 سم، على التوالي. يبدأ السداد الجرية في العمل كهدار يفيض الماء من فوقه عندما يكون متوسط عمق الماء إلى ارتفاع السداد (H / P) هو 1.19، في حين أن متوسط الزيادة الإجمالية في التصريف نسبة إلى تصريف السد الصلب هو 15 ٪. كما تم أقتراح علاقات تجريبية للتنبؤ بعمق الماء المتجمع أمام السداد الحجرية لكل من أنظمة التدفق الثلاثة. كما تم اقتراح علاقة تجريبية عديمة الابعاد للتنبؤ بمعامل التصريف لهذة السداد وبدقة جيدة.The variation between flow depth generated in front of gabion barrier and flow rate has been studied in open laboratory flume. Flow profiles have been observed for each of "Transition Flow" and "Overflow" regimes. Effects of gabion height and material coarseness on the upstream flow depth are studied by testing four different gabion heights and four different medium aggregate sizes. The analysis of experimental results showed that the relative decrease in flow depth varies between 38% and 17% for "Through Flow" type when material coarseness and discharge increase. In "Transition Flow" regime, increasing material coarseness and discharge causes an average decreases in relative flow depth of 7.6% and 4.4% for gabion heights 15cm and 30cm, respectively. Gabion begins to operate as an overflow weir when the average water depth to the gabion height (H/P) is 1.19. While the overall average increase in discharge relative to solid weir is 15%. Prediction relationships for flow depth upstream the gabion for each of the three flow regimes is suggested. Also, dimensionless relation to predict discharge coefficient are proposed with good accuracy
Properties of Flow through and over Gravel Basket Weir
يؤدي إنشاء هدارات من سلال الحصى في المجاري المائية إلى تراكم المياه أمام هذه المشأت المسامية، ويكون فيها منسوب المياه أقل من تلك التي تتجمع مقدمة الهدارات الصلبة. تتضمن هذه الدراسة، تقديرعمق الماء المتجمع امام هذه الهدارات مع قياس شكل السطح الحر للجريان والتنبؤ بقيمة معامل التصريف من خلال التجارب المختبرية. كما تمت دراسة أربعة أطوال مختلفة من الهدارات (15 ، 20 ، 25 و 30 سم) وأربع خشونات مختلفة من الحصى (1.13 ، 1.58 ، 2.19 و 2.27). وفقًا لذلك، فقد تم اختبارستة عشر نموذجاً في ظروف مختلفة من التدفق الحر. أظهرتحليل نتائج نظام الجريان "التدفق النافذ" أن الزيادة في عرض السد تسبب في زيادة عمق الماء المتجمع امام الهدارات ولجميع درجات الخشونة بنسبة 30٪ بينما تقلل الخشونة من العمق بنسبة 28٪. وفي "التدفق الانتقالي"، يؤدي مضاعفة الطول إلى زيادة عمق التدفق بنسبة 7٪، بينما تؤدي زيادة الخشونة من 1.13 إلى 2.72 سم في انخفاض عمق الجريان بنسبة 7٪. يبدأ نظام "التدفق الفائض" بالظهورعندما تساوي نسبة عمق الماء إلى عرض السد حوالي 0.75 للعرض الكبير و1.54 للعرض القليل. تشير المقارنة بين هدارات سلال الحصى والهدارات الصلبة إلى أن متوسط تقليل عمق الماء هو 7.5٪ للصلابة البالغة 1.13 سم و9٪ للصلابة البالغة 2.72 سم. تم اقتراح نماذج رياضية للتنبؤ بعمق المياه لأنظمة التدفق الثلاثة، أما بالنسبة لنظام "التدفق الفائض"، فقد اقتُرِحَت صيغة تجريبية لتقدير معامل التصريف بدقة مقبولة.Construction of gravel basket weir in waterways causes water accumulation in front of this porous structure less than solid weir. In the present study the upstream flow depth, water surface profile and discharge coefficient are investigated through laboratory experiments. Four different weir lengths (15, 20, 25 and 30 cm) and four different degrees of gravel coarseness (1.13, 1.58, 2.19 and 2.27) are studied. Accordingly, sixteen models are tested under different free flow conditions. Analysis of the results show that in "through flow" regime the increase in weir length raises the generated upstream depth for all coarseness degrees by 30% while coarseness lowers the depth by 28%. In "transition flow", however, doubling the length increases the flow depth by 7%, but increasing coarseness from 1.13 to 2.72 cm mean diameter causes 7% reduction in flow depth. The "overflow" regime begins to appear when the depth to length ratio equals 0.75 for long weir, and about 1.54 for shortest weir. A comparison between gravel basket weir and corresponding solid weir indicates that average depth reduction is 7.5% for coarseness of 1.13 cm and 9% for coarseness of 2.72 cm. Mathematical models for water depth prediction for the three flow regimes are presented. For "overflow" an empirical formula is proposed to estimate the coefficient of discharge with acceptable accuracy
Magnetic resonance imaging of the left wrist: assessment of the bone age in a sample of healthy Iraqi adolescent males
Background: Use of magnetic resonance imaging (MRI) to calculate skeletal age is a novel idea. MRI provides excellent soft-tissue contrast and multiplanar cross-sectional imaging capability. It could be used as an alternative method of skeletal age determination.
Objectives: To study the value of MRI in estimating the age of healthy Iraqi adolescent males and to compare the obtained results with other countries records.
Population and methods: This cross sectional study was applied on 179 healthy adolescent males between the ages of 13 to18 years in MRI unit at radiology institute in medical city, Baghdad – Iraq. This study was carried out from November 2011 to December 2012. Magnetic resonance imaging of the left wrist was performed by using a 1.5Tesla machine with surface coil. The sequence used was coronal T1weighted images (WI). The degree of fusion of the left distal radial physis was determined by a newly developed grading system.
Results: There is high correlation between chronological age and degree of fusion of distal radius within the participant population. Most adolescent boys in the age group between 13 and 14 years presented as grade I and II, while the complete fusion was found at the age of 17and18 years, the mean age of participants was 17.5 years. Degree of fusion of the distal radius in the sample of the study was almost approaching the obtained values in the Algeria and Malaysia as comparative countries.
Conclusion: MRI offers an alternative; non-invasive method of examination of the epiphysial fusion, which eliminates any risk associated with standard radiographic rating. The grading system can accurately identify the variable degrees of epiphysial fusion in an objective teachable manner
Virtual data integration for a clinical decision support systems
Clinical decision support (CDS) supplies clinicians and their patients, and relevant staff with meaningful and timely information intelligently integrated or visualized to enhance health and the health sector. Data is the backbone of decision support systems, especially (clinical) ones. Data integration (either virtual or physical manner) is a powerful technique to manipulate a vast amount of heterogeneous data and prepare it as input for the decision-making process. The difficulties in manipulating data that have a physical data integration technique motivated the decision support developers to tend to data virtualization as a data integration technique. In this paper, a clinical decision support system was developed using the virtual data integration technique. The developed system was evaluated in terms of usability and its capability of providing clinical decision support. The evaluation findings indicate that the proposed system is highly usable and has a positive impact on supporting the clinical decision-making process
Adolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019
Background Globally, transport and unintentional injuries persist as leading preventable causes of mortality and morbidity for adolescents. We sought to report comprehensive trends in injury-related mortality and morbidity for adolescents aged 10-24 years during the past three decades.
Methods Using the Global Burden of Disease, Injuries, and Risk Factors 2019 Study, we analysed mortality and disability-adjusted life-years (DALYs) attributed to transport and unintentional injuries for adolescents in 204 countries. Burden is reported in absolute numbers and age-standardised rates per 100 000 population by sex, age group (10-14, 15-19, and 20-24 years), and sociodemographic index (SDI) with 95% uncertainty intervals (UIs). We report percentage changes in deaths and DALYs between 1990 and 2019.
Findings In 2019, 369 061 deaths (of which 214337 [58%] were transport related) and 31.1 million DALYs (of which 16.2 million [52%] were transport related) among adolescents aged 10-24 years were caused by transport and unintentional injuries combined. If compared with other causes, transport and unintentional injuries combined accounted for 25% of deaths and 14% of DALYs in 2019, and showed little improvement from 1990 when such injuries accounted for 26% of adolescent deaths and 17% of adolescent DALYs. Throughout adolescence, transport and unintentional injury fatality rates increased by age group. The unintentional injury burden was higher among males than females for all injury types, except for injuries related to fire, heat, and hot substances, or to adverse effects of medical treatment. From 1990 to 2019, global mortality rates declined by 34.4% (from 17.5 to 11.5 per 100 000) for transport injuries, and by 47.7% (from 15.9 to 8.3 per 100000) for unintentional injuries. However, in low-SDI nations the absolute number of deaths increased (by 80.5% to 42 774 for transport injuries and by 39.4% to 31 961 for unintentional injuries). In the high-SDI quintile in 2010-19, the rate per 100 000 of transport injury DALYs was reduced by 16.7%, from 838 in 2010 to 699 in 2019. This was a substantially slower pace of reduction compared with the 48.5% reduction between 1990 and 2010, from 1626 per 100 000 in 1990 to 838 per 100 000 in 2010. Between 2010 and 2019, the rate of unintentional injury DALYs per 100 000 also remained largely unchanged in high-SDI countries (555 in 2010 vs 554 in 2019; 0.2% reduction). The number and rate of adolescent deaths and DALYs owing to environmental heat and cold exposure increased for the high-SDI quintile during 2010-19.
Interpretation As other causes of mortality are addressed, inadequate progress in reducing transport and unintentional injury mortality as a proportion of adolescent deaths becomes apparent. The relative shift in the burden of injury from high-SDI countries to low and low-middle-SDI countries necessitates focused action, including global donor, government, and industry investment in injury prevention. The persisting burden of DALYs related to transport and unintentional injuries indicates a need to prioritise innovative measures for the primary prevention of adolescent injury
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Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019
Summary
Background
The global burden of lower respiratory infections (LRIs) and corresponding risk factors in children older than 5 years and adults has not been studied as comprehensively as it has been in children younger than 5 years. We assessed the burden and trends of LRIs and risk factors across all age groups by sex, for 204 countries and territories.
Methods
In this analysis of data for the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we used clinician-diagnosed pneumonia or bronchiolitis as our case definition for LRIs. We included International Classification of Diseases 9th edition codes 079.6, 466–469, 470.0, 480–482.8, 483.0–483.9, 484.1–484.2, 484.6–484.7, and 487–489 and International Classification of Diseases 10th edition codes A48.1, A70, B97.4–B97.6, J09–J15.8, J16–J16.9, J20–J21.9, J91.0, P23.0–P23.4, and U04–U04.9. We used the Cause of Death Ensemble modelling strategy to analyse 23 109 site-years of vital registration data, 825 site-years of sample vital registration data, 1766 site-years of verbal autopsy data, and 681 site-years of mortality surveillance data. We used DisMod-MR 2.1, a Bayesian meta-regression tool, to analyse age–sex-specific incidence and prevalence data identified via systematic reviews of the literature, population-based survey data, and claims and inpatient data. Additionally, we estimated age–sex-specific LRI mortality that is attributable to the independent effects of 14 risk factors.
Findings
Globally, in 2019, we estimated that there were 257 million (95% uncertainty interval [UI] 240–275) LRI incident episodes in males and 232 million (217–248) in females. In the same year, LRIs accounted for 1·30 million (95% UI 1·18–1·42) male deaths and 1·20 million (1·07–1·33) female deaths. Age-standardised incidence and mortality rates were 1·17 times (95% UI 1·16–1·18) and 1·31 times (95% UI 1·23–1·41) greater in males than in females in 2019. Between 1990 and 2019, LRI incidence and mortality rates declined at different rates across age groups and an increase in LRI episodes and deaths was estimated among all adult age groups, with males aged 70 years and older having the highest increase in LRI episodes (126·0% [95% UI 121·4–131·1]) and deaths (100·0% [83·4–115·9]). During the same period, LRI episodes and deaths in children younger than 15 years were estimated to have decreased, and the greatest decline was observed for LRI deaths in males younger than 5 years (–70·7% [–77·2 to –61·8]). The leading risk factors for LRI mortality varied across age groups and sex. More than half of global LRI deaths in children younger than 5 years were attributable to child wasting (population attributable fraction [PAF] 53·0% [95% UI 37·7–61·8] in males and 56·4% [40·7–65·1] in females), and more than a quarter of LRI deaths among those aged 5–14 years were attributable to household air pollution (PAF 26·0% [95% UI 16·6–35·5] for males and PAF 25·8% [16·3–35·4] for females). PAFs of male LRI deaths attributed to smoking were 20·4% (95% UI 15·4–25·2) in those aged 15–49 years, 30·5% (24·1–36·9) in those aged 50–69 years, and 21·9% (16·8–27·3) in those aged 70 years and older. PAFs of female LRI deaths attributed to household air pollution were 21·1% (95% UI 14·5–27·9) in those aged 15–49 years and 18·2% (12·5–24·5) in those aged 50–69 years. For females aged 70 years and older, the leading risk factor, ambient particulate matter, was responsible for 11·7% (95% UI 8·2–15·8) of LRI deaths.
Interpretation
The patterns and progress in reducing the burden of LRIs and key risk factors for mortality varied across age groups and sexes. The progress seen in children younger than 5 years was clearly a result of targeted interventions, such as vaccination and reduction of exposure to risk factors. Similar interventions for other age groups could contribute to the achievement of multiple Sustainable Development Goals targets, including promoting wellbeing at all ages and reducing health inequalities. Interventions, including addressing risk factors such as child wasting, smoking, ambient particulate matter pollution, and household air pollution, would prevent deaths and reduce health disparities
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Global mortality associated with 33 bacterial pathogens in 2019: a systematic analysis for the Global Burden of Disease Study 2019
Summary
Background
Reducing the burden of death due to infection is an urgent global public health priority. Previous studies have estimated the number of deaths associated with drug-resistant infections and sepsis and found that infections remain a leading cause of death globally. Understanding the global burden of common bacterial pathogens (both susceptible and resistant to antimicrobials) is essential to identify the greatest threats to public health. To our knowledge, this is the first study to present global comprehensive estimates of deaths associated with 33 bacterial pathogens across 11 major infectious syndromes.
Methods
We estimated deaths associated with 33 bacterial genera or species across 11 infectious syndromes in 2019 using methods from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, in addition to a subset of the input data described in the Global Burden of Antimicrobial Resistance 2019 study. This study included 343 million individual records or isolates covering 11 361 study-location-years. We used three modelling steps to estimate the number of deaths associated with each pathogen: deaths in which infection had a role, the fraction of deaths due to infection that are attributable to a given infectious syndrome, and the fraction of deaths due to an infectious syndrome that are attributable to a given pathogen. Estimates were produced for all ages and for males and females across 204 countries and territories in 2019. 95% uncertainty intervals (UIs) were calculated for final estimates of deaths and infections associated with the 33 bacterial pathogens following standard GBD methods by taking the 2·5th and 97·5th percentiles across 1000 posterior draws for each quantity of interest.
Findings
From an estimated 13·7 million (95% UI 10·9–17·1) infection-related deaths in 2019, there were 7·7 million deaths (5·7–10·2) associated with the 33 bacterial pathogens (both resistant and susceptible to antimicrobials) across the 11 infectious syndromes estimated in this study. We estimated deaths associated with the 33 bacterial pathogens to comprise 13·6% (10·2–18·1) of all global deaths and 56·2% (52·1–60·1) of all sepsis-related deaths in 2019. Five leading pathogens—Staphylococcus aureus, Escherichia coli, Streptococcus pneumoniae, Klebsiella pneumoniae, and Pseudomonas aeruginosa—were responsible for 54·9% (52·9–56·9) of deaths among the investigated bacteria. The deadliest infectious syndromes and pathogens varied by location and age. The age-standardised mortality rate associated with these bacterial pathogens was highest in the sub-Saharan Africa super-region, with 230 deaths (185–285) per 100 000 population, and lowest in the high-income super-region, with 52·2 deaths (37·4–71·5) per 100 000 population. S aureus was the leading bacterial cause of death in 135 countries and was also associated with the most deaths in individuals older than 15 years, globally. Among children younger than 5 years, S pneumoniae was the pathogen associated with the most deaths. In 2019, more than 6 million deaths occurred as a result of three bacterial infectious syndromes, with lower respiratory infections and bloodstream infections each causing more than 2 million deaths and peritoneal and intra-abdominal infections causing more than 1 million deaths.
Interpretation
The 33 bacterial pathogens that we investigated in this study are a substantial source of health loss globally, with considerable variation in their distribution across infectious syndromes and locations. Compared with GBD Level 3 underlying causes of death, deaths associated with these bacteria would rank as the second leading cause of death globally in 2019; hence, they should be considered an urgent priority for intervention within the global health community. Strategies to address the burden of bacterial infections include infection prevention, optimised use of antibiotics, improved capacity for microbiological analysis, vaccine development, and improved and more pervasive use of available vaccines. These estimates can be used to help set priorities for vaccine need, demand, and development