A new dryland development paradigm grounded in empirical analysis of dryland systems science

Global drylands face a host of urgent human and environmental challenges with far-reaching impacts. Improving smallholder agriculture remains a key development pathway to tackle these challenges. The Dryland Development Paradigm (DDP), introduced in 2007, presented a highly influential framework for dryland development based on systems research. This paper empirically derives a new, updated DDP. It assesses recent, cutting-edge dryland science, combining literature review with qualitative and quantitative analysis of research published by the world's largest dryland science and development research initiative. The new DDP comprises eight characteristics that are distilled into three integrative principles: Unpack, Traverse and Share. The new DDP is applied and tested to identify key dryland knowledge and development gaps. A future research agenda is then elucidated, grounded in a research in development approach, in which research anchored in the three integrative principles is embedded within the context it seeks to improve. Supported by greater transdisciplinarity and knowledge co-production, operationalization of the new DDP can deliver both novel scientific insights and development impact in line with the aspirations of the 2030 Sustainable Development Goals

How to keep it adequate: A protocol for ensuring validity in agent-based simulation

There has so far been no shared understanding of validity in agent-based simulation. We here conceptualise validation as systematically substantiating the premises on which conclusions from simulation analysis for a particular modelling context are built. Given such a systematic perspective, validity of agent-based models cannot be ensured if validation is merely understood as an isolated step in the modelling process. Rather, valid conclusions from simulation analysis require context-adequate method choices at all steps of the simulation analysis including model construction, model and parameter inference, uncertainty analysis and simulation. We present a twelve-step protocol to highlight the (often hidden) premises for methodological choices and their link to the modelling context. It is designed to aid modelers in understanding their context and in choosing and documenting context-adequate and mutually consistent methods throughout the modelling process. Its purpose is to assist reviewers and the community as a whole in assessing and discussing context-adequacy

RQM description of the charge form factor of the pion and its asymptotic behavior

The pion charge and scalar form factors, $F_1(Q^2)$ and $F_0(Q^2)$, are first calculated in different forms of relativistic quantum mechanics. This is done using the solution of a mass operator that contains both confinement and one-gluon-exchange interactions. Results of calculations, based on a one-body current, are compared to experiment for the first one. As it could be expected, those point-form, and instant and front-form ones in a parallel momentum configuration fail to reproduce experiment. The other results corresponding to a perpendicular momentum configuration (instant form in the Breit frame and front form with $q^+=0$) do much better. The comparison of charge and scalar form factors shows that the spin-1/2 nature of the constituents plays an important role. Taking into account that only the last set of results represents a reasonable basis for improving the description of the charge form factor, this one is then discussed with regard to the asymptotic QCD-power-law behavior $Q^{-2}$. The contribution of two-body currents in achieving the right power law is considered while the scalar form factor, $F_0(Q^2)$, is shown to have the right power-law behavior in any case. The low-$Q^2$ behavior of the charge form factor and the pion-decay constant are also discussed.}Comment: 30 pages, 10 figure

Global Retinoblastoma Presentation and Analysis by National Income Level

Importance: Early diagnosis of retinoblastoma, the most common intraocular cancer, can save both a child's life and vision. However, anecdotal evidence suggests that many children across the world are diagnosed late. To our knowledge, the clinical presentation of retinoblastoma has never been assessed on a global scale. Objectives: To report the retinoblastoma stage at diagnosis in patients across the world during a single year, to investigate associations between clinical variables and national income level, and to investigate risk factors for advanced disease at diagnosis. Design, Setting, and Participants: A total of 278 retinoblastoma treatment centers were recruited from June 2017 through December 2018 to participate in a cross-sectional analysis of treatment-naive patients with retinoblastoma who were diagnosed in 2017. Main Outcomes and Measures: Age at presentation, proportion of familial history of retinoblastoma, and tumor stage and metastasis. Results: The cohort included 4351 new patients from 153 countries; the median age at diagnosis was 30.5 (interquartile range, 18.3-45.9) months, and 1976 patients (45.4) were female. Most patients (n = 3685 84.7%) were from low-and middle-income countries (LMICs). Globally, the most common indication for referral was leukocoria (n = 2638 62.8%), followed by strabismus (n = 429 10.2%) and proptosis (n = 309 7.4%). Patients from high-income countries (HICs) were diagnosed at a median age of 14.1 months, with 656 of 666 (98.5%) patients having intraocular retinoblastoma and 2 (0.3%) having metastasis. Patients from low-income countries were diagnosed at a median age of 30.5 months, with 256 of 521 (49.1%) having extraocular retinoblastoma and 94 of 498 (18.9%) having metastasis. Lower national income level was associated with older presentation age, higher proportion of locally advanced disease and distant metastasis, and smaller proportion of familial history of retinoblastoma. Advanced disease at diagnosis was more common in LMICs even after adjusting for age (odds ratio for low-income countries vs upper-middle-income countries and HICs, 17.92 95% CI, 12.94-24.80, and for lower-middle-income countries vs upper-middle-income countries and HICs, 5.74 95% CI, 4.30-7.68). Conclusions and Relevance: This study is estimated to have included more than half of all new retinoblastoma cases worldwide in 2017. Children from LMICs, where the main global retinoblastoma burden lies, presented at an older age with more advanced disease and demonstrated a smaller proportion of familial history of retinoblastoma, likely because many do not reach a childbearing age. Given that retinoblastoma is curable, these data are concerning and mandate intervention at national and international levels. Further studies are needed to investigate factors, other than age at presentation, that may be associated with advanced disease in LMICs. © 2020 American Medical Association. All rights reserved

The extent and cost of land degradation

Non-PRIFPRI4; CRP5EPTDCGIAR Research Program on Water, Land and Ecosystems (WLE); CGIAR Research Program on Dryland System

Biodiversity in rubber agroforests, carbon emissions, and rural livelihoods: An agent-based model of land-use dynamics in lowland Sumatra

Rubber agroforests in the mostly deforested lowlands of Sumatra, Indonesia are threatened by conversion into monoculture rubber or oil palm plantations. We applied an agent-based model to explore the potential effectiveness of a payment for ecosystem services (PES) design through a biodiversity rich rubber eco-certification scheme. We integrated conditionality, where compliance with biodiversity performance indicators is prerequisite for awarding incentives. We compared a PES policy scenario to ‘business-as-usual’ and ‘subsidized land use change’ scenarios to explore potential trade-offs between ecosystem services delivery and rural income. Results indicated that a rubber agroforest eco-certification scheme could reduce carbon emissions and species loss better than alternative scenarios. However, the suggested premiums were too low to compete with income from other land uses. Nevertheless, integrating our understanding of household agent behavior through a spatially explicit and agent-specific assessment of the trade-offs can help refine the design of conservation initiatives such as PES

Recycled cellulose aerogels from paper waste for a heat insulation design of canteen bottles

10.3390/fluids4030174Fluids4