32 research outputs found
Psicología, directrices curriculares y procesos educativos en la Amazonía: un estudio de la formación de psicólogos
Este estudo objetiva analisar a formação de psicólogos frente às Diretrizes Curriculares Nacionais para os Cursos de Psicologia no que tange aos processos educativos. Realizamos revisão da literatura pertinente ao tema, pesquisa documental e empírica com alunos, professores e coordenador de curso, utilizando questionário, entrevistas e adotando a estratégia de triangulação a partir das categorias: perfil sociocultural; nível de conhecimento acerca das mudanças oriundas das Diretrizes para o curso de Psicologia; percepção na qualidade da prática docente; nível de satisfação com relação à própria formação universitária, tomando como referência os conhecimentos, habilidades e competências adquiridas. Apresenta contribuições para a compreensão da formação de psicólogos no campo da educação na Amazônia no Ensino Superior, centrada na construção de um profissional de pensamento e prática críticos, capaz de analisar as transformações nos vários contextos educacionais e escolares, utilizando referenciais que permitam a compreensão do fenômeno educativo na sua complexidade.In this study we aim at analyzing the psychologist education related to National Curriculum Guidelines (PCN) for the Psychology course when referring to the educational knowledge process. We have anylized the literature related to the theme, as well as we did a documental and empirical research with students, professors, course coordinators, by using questionnaires, interviews and by adopting a triangle strategy, starting from the categories: socio-cultural profile, level of knowledge around the changes coming from the Curriculum guidelines for the course of Psychology; perception of the quality of the teaching practice and level of satisfaction related to the university education considering the knowledge and skills acquired from it. We propose some contributions to the educational psychologist in the field of Education in higher education in the Amazon region. This contribution should be centered on the constructing of a critical thinking and practice, capable of analyzing the transformation, visible in several educational and school contexts, based on concepts that favor the understanding of the complex educative phenomenon.Este estudio tiene el objetivo de analizar la formación de psicólogos frente a las Directrices Curriculares Nacionales para los Cursos de Psicología en lo que dice respecto a los procesos educativos. Realizamos revisión de la literatura pertinente al tema, investigación documental y empírica con alumnos, profesores, coordinador de curso. Se utilizó cuestionario, entrevistas y se adoptó la estrategia de triangulación, a partir de las categorías: perfil sociocultural; nivel de conocimiento acerca de los cambios oriundos de las Directrices para el curso de Psicología; percepción de la calidad de práctica docente; nivel de satisfacción en relación a la propia formación universitaria, tomando como referencia los conocimientos, habilidades y competencias adquiridas. Presentamos contribuciones para la comprensión de la formación de psicólogos en el campo de la educación en la Amazonía en la enseñanza superior, centrada en la construcción de un profesional de pensamiento y práctica críticos, capaz de analizar las transformaciones en los varios contextos educacionales y escolares, utilizando referenciales que permitan la comprensión del fenómeno educativo en su complejidad.CNP
Lean Optimization Techniques for Improvement of Production Flows and Logistics Management: The Case Study of a Fruits Distribution Center
The organizations of horticultural producers and, particularly, those that deal with extremely
perishable endogenous fruits, such as peaches and cherries, have a greater need to optimize
production flows and processes. A particularity of the horticultural industry is the short shelf life
of raw materials and the seasonality of products. In this paper, optimization techniques are used
to improve the production flows and the management of cold storage and distribution in a fruit
central. The application of Lean tools allowed reducing the cycle time by 4.37 min and the lead time
by 7.10 min of the whole process, i.e., a reduction of 35.5% and 10.6% of the cycle time and lead time,
respectively, excluding the cold conservation operation. The study shows that it is possible to reduce,
or even eliminate, waste throughout the process, reduce unnecessary movement, adapt the layout,
maximize workspace, and level stocks, as well as greater supplier involvement in a continuous
improvement approach. This approach can be outlined as a good practice for the optimization of
productive flows and management logistics that may benefit productivity, energy efficiency, human
resources distribution, food quality, and reduce food waste.info:eu-repo/semantics/publishedVersio
As pin-ups contemporâneas
À luz da análise do discurso francesa, na sua interlocução com um referencial teórico ligado, mais especificamente, à moda, analisamos, no presente artigo, produções discursivas extraídas de blogs atuais com temática retrô que foram criados por mulheres brasileiras, a fim de apreender como se elaboram os éthe daquelas que, na contemporaneidade, autodenominam-se “pin-ups modernas”. Por meio do exame dos discursos manifestados em seus blogs, conseguimos vislumbrar pontos de contato e de distanciamento entre as construções ethóticas que elas promovem. Assim, se a referência ao universo retrô é aquilo que as une, cada uma homenageia o passado a partir do bojo de suas vivências, projetando uma imagem singular. Este estudo nos permitiu, portanto, constatar a eficiência da noção de éthos como instrumento de análise capaz de deslindar o universo cultural retrô imbricado nos dizeres das blogueiras
Applying a Genetic Algorithm to a m-TSP: Case Study of a Decision Support System for Optimizing a Beverage Logistics Vehicles Routing Problem
Route optimization has become an increasing problem in the transportation and logistics sector within the development of smart cities. This article aims to demonstrate the implementation of a genetic algorithm adapted to a Vehicle Route Problem (VRP) in a company based in the city of Covilhã (Portugal). Basing the entire approach to this problem on the characteristic assumptions of the Multiple Traveling Salesman Problem (m-TSP) approach, an optimization of the daily routes for the workers assigned to distribution, divided into three zones: North, South and Central, was performed. A critical approach to the returned routes based on the adaptation to the geography of the Zones was performed. From a comparison with the data provided by the company, it is predicted by the application of a genetic algorithm to the m-TSP, that there will be a reduction
of 618 km per week of the total distance traveled. This result has a huge impact in several forms: clients are visited in time, promoting provider-client relations; reduction of the fixed costs with fuel; promotion of environmental sustainability by the reduction of logistic routes. All these improvements and optimizations can be thought of as contributions to foster smart cities.Fundação para a Ciência e a Tecnologia (FCT—MCTES) for its financial support via the project UIDB/00151/2020 (C-MAST).info:eu-repo/semantics/publishedVersio
Mitochondrial dynamics and quality control in Huntington's disease
Huntington's disease (HD) is an inherited neurodegenerative disorder caused by polyglutamine expansion mutations in the huntingtin protein. Despite its ubiquitous distribution, expression of mutant huntingtin (mHtt) is particularly detrimental to medium spiny neurons within the striatum. Mitochondrial dysfunction has been associated with HD pathogenesis. Here we review the current evidence for mHtt-induced abnormalities in mitochondrial dynamics and quality control, with a particular focus on brain and neuronal data pertaining to striatal vulnerability. We address mHtt effects on mitochondrial biogenesis, protein import, complex assembly, fission and fusion, mitochondrial transport, and on the degradation of damaged mitochondria via autophagy (mitophagy). For an integrated perspective on potentially converging pathogenic mechanisms, we also address impaired autophagosomal transport and abnormal mHtt proteostasis in HD
HDAC6 inhibition induces mitochondrial fusion, autophagic flux and reduces diffuse mutant huntingtin in striatal neurons
Striatal neurons are vulnerable to Huntington's disease (HD). Decreased levels of acetylated alpha-tubulin and impaired mitochondrial dynamics, such as reduced motility and excessive fission, are associated with HD; however, it remains unclear whether and how these factors might contribute to the preferential degeneration of striatal neurons. Inhibition of the alpha-tubulin deacetylase HDAC6 has been proposed as a therapeutic strategy for HD, but remains controversial - studies in neurons show improved intracellular transport, whereas studies in cell-lines suggest it may impair autophagosome-lysosome fusion, and reduce clearance of mutant huntingtin (mHtt) and damaged mitochondria (mitophagy). Using primary cultures of rat striatal and cortical neurons, we show that mitochondria are intrinsically less motile and more balanced towards fission in striatal than in cortical neurons. Pharmacological inhibition of the HDAC6 deacetylase activity with tubastatin A (TBA) increased acetylated alpha-tubulin levels, and induced mitochondrial motility and fusion in striatal neurons to levels observed in cortical neurons. Importantly, TBA did not block neuronal autophagosome-lysosome fusion, and did not change mitochondrial DNA levels, suggesting no impairment in autophagy or mitochondrial clearance. Instead, TBA increased autophagic flux and reduced diffuse mHtt in striatal neurons, possibly by promoting transport of initiation factors to sites of autophagosomal biogenesis. This study identifies the pharmacological inhibition of HDAC6 deacetylase activity as a potential strategy to reduce the vulnerability of striatal neurons to HD
Composição e abundância de macrófitas num troço do rio Ovelha
As macrófitas fluviais são um grupo relevante para a avaliação ecológica dos rios. Numa
amostragem realizada num troço de 100 m do rio Ovelha, localizado a 217 m de altitude,
na freguesia de Fornos, Marco de Canaveses, estudou-se a abundância, composição e
distribuição das macrófitas. Verificou-se que o troço estudado é pobre em macrófitas,
apresentando uma riqueza específica baixa, o que poderá estar relacionado, sobretudo, com
o substrato rochoso. Considerando os resultados obtidos é fundamental que, futuramente,
sejam estudadas as macrófitas conjuntamente com outros elementos biológicos, no sentido
de se proceder a uma correta monitorização do estado ecológico do rio Ovelha.info:eu-repo/semantics/publishedVersio
COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study
Background:
The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms.
Methods:
International, prospective observational study of 60 109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms.
Results:
‘Typical’ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (≤ 18 years: 69, 48, 23; 85%), older adults (≥ 70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each P < 0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country.
Interpretation:
This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men
O ensino de Gil Vicente no Ensino Básico e Secundário
Pretendemos, neste trabalho, analisar o estudo de Gil Vicente nos programas e
manuais do ensino básico e secundário.
Sendo ele um autor de grande índole cabe-nos analisar se as suas obras que estão a
ser estudadas corretamente e em que ciclos de estudos. Cabe-nos também analisar os
manuais de 9º ano e 10º ano de literatura, pois são os únicos onde encontramos Gil Vicente. É
importante perceber quais as obras que são escolhidas e também o porquê, já que muitas
vezes são escolhidas por influência do manual.
Para além disso, incluímos ainda na presente dissertação, como, de resto, não podia
deixar de ser, o relatório de estágio pedagógico, que reflete toda a experiência vivida na
Escola Secundária do Fundão, dando, por conseguinte, conta de aspetos como a
caracterização da escola, as aulas assistidas e atividades extracurriculares.Nos proponemos en este trabajo para analizar el estudio de Gil Vicente en los
programas y libros en la enseñanza primaria y secundaria.
Siendo un autor de gran carácter nos corresponde examinar si sus obras se están
abordando adecuadamente y en qué ciclos. Nos corresponde también analizar los manuales de
3º de eso y 1º de bachillerato de literatura, ya que son los únicos en los que encontramos a
Gil Vicente. Es importante darse cuenta de qué tipo de obras se eligen y también por qué, ya
que a menudo son elegidas por influencias del manual.
Además, hemos incluido en la presente disertación una compilación de todo lo
realizado en las prácticas pedagógicas, que reflete toda la experiencia vivida en la Escola
Secundária do Fundão, refiriendo, por eso aspectos como la caracterización de la escuela, las
clases y actividades extracurriculares
Estratégias para estimulação cognitiva das pessoas idosas com demência
info:eu-repo/semantics/publishedVersio