14 research outputs found

    STUDY AND MODIFICATION OF SOOT BLOWER IN SUGAR INDUSTRY

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    Due to the unbalancing of the impeller of soot blower the vibrations are generated which causes the damage to the soot blower and get breakdown after some time period of working

    “I526L” - Growth hormone receptor gene variant and its effect on craniofacial morphology

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    Objectives & Setting: To investigate the influence of GHR (Growth Hormone Receptor) gene variant (I526L) on craniofacial morphology. The department of orthodontics, D.A.P.M.R.V.Dental College and Hospital, Bangalore, India.30 randomly selected subjects, aged 20-30 years who were patients at D.A.P.M.R.V.Dental College & Hospital, Bangalore. Materials and methods DNA was extracted from venous blood samples of all the subjects. The extracted DNA samples were subjected to polymerase chain reaction, where amplification of the selected gene segments was done and later these amplified products were subjected to restriction fragment length polymorphism using HpyCH4V restriction enzyme. Results were documented in specific bands with gel documentation centre. The effects of the gene variant on the 4 craniofacial morphologic parameters of anterior cranial base length, maxillary length, mandibular ramus length/height and mandibular length were obtained from lateral cephalograms and tabulated. Appropriate statistical analysis was carried out. Results The results indicated that the subjects with I526L variant of GHR gene had a significantly greater mandibular ramus height. GHR gene variant I526L could be a genetic marker for mandibular ramus height. Conclusion This study indicates that subjects with I526L variant of GHR gene had a significantly greater mandibular ramus height .GHR gene variant I526L could be a genetic marker for mandibular ramus height. &nbsp

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    Not AvailableAccurate yield estimation has always been a matter of challenge to the scientific community especially so in the recent times due to the heightened risk of climatic variability. This study explored the statistical technique of fixed effect panel regression for estimation of the district-wise wheat yield using weather as well as satellite remote sensing indices. As wheat crop is sensitive to heat, temperature during the reproductive stage was used for modelling. Along with that trend adjusted vegetation condition index (VCITadj), temperature condition index (TCI) and vegetation health index (VHI) during the thermo-sensitive reproductive phase (TSP) was also used for modelling of wheat yield. The results show that, models developed with extreme temperature and remote sensing indices could capture the broad variation in district-wise wheat yield. The error was higher for extreme temperature based model as compared to the remote sensing based models. Among the remote sensing based models, VHI based one outperformed both the TCI and VCITadj based models which may be due to the reason that VHI combines both the information about greenness as well as temperature stress in it. The error in estimated yield varied based on the model but it was below 10% for all the districts for VHI based model. Further, it was seen that the accuracy was good for first year of prediction but it decreases for the second year. It indicates that the model should be used in a rolling mode, updating the parameters in each year before using it for next year.ICAR - National Innovations in Climate Resilient Agriculture (NICRA) ProjectIARI In-house Project Grant IARI:NRM:14:(04

    GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.

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    Carotid artery intima media thickness (cIMT) and carotid plaque are measures of subclinical atherosclerosis associated with ischemic stroke and coronary heart disease (CHD). Here, we undertake meta-analyses of genome-wide association studies (GWAS) in 71,128 individuals for cIMT, and 48,434 individuals for carotid plaque traits. We identify eight novel susceptibility loci for cIMT, one independent association at the previously-identified PINX1 locus, and one novel locus for carotid plaque. Colocalization analysis with nearby vascular expression quantitative loci (cis-eQTLs) derived from arterial wall and metabolic tissues obtained from patients with CHD identifies candidate genes at two potentially additional loci, ADAMTS9 and LOXL4. LD score regression reveals significant genetic correlations between cIMT and plaque traits, and both cIMT and plaque with CHD, any stroke subtype and ischemic stroke. Our study provides insights into genes and tissue-specific regulatory mechanisms linking atherosclerosis both to its functional genomic origins and its clinical consequences in humans

    Nanotechnology: Revolutionizing the Science of Drug Delivery

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    Measurement of the fractional radiation length of a pixel module for the CMS Phase-2 upgrade via the multiple scattering of positrons

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    International audienceHigh-luminosity particle collider experiments such as the ones planned at the High-Luminosity Large Hadron Collider require ever-greater vertexing precision of the tracking detectors, necessitating also reductions in the material budget of the detectors. Traditionally, the fractional radiation length (x/X0x/X_0) of detectors is either estimated using known properties of the constituent materials, or measured in dedicated runs of the final detector. In this paper, we present a method of direct measurement of the material budget of a CMS prototype module designed for the Phase-2 upgrade of the CMS detector using a 40-65 MeV positron beam. A total of 630 million events were collected at the Paul Scherrer Institut PiE1 experimental area using a three-plane telescope consisting of the prototype module as the central plane, surrounded by two MALTA monolithic pixel detectors. Fractional radiation lengths were extracted from scattering angle distributions using the Highland approximation for multiple scattering. A statistical technique recovered runs suffering from trigger desynchronisation, and several corrections were introduced to compensate for local inefficiencies related to geometric and beam shape constraints. An overall average x/X0x/X_0 of (0.84 ±\pm 0.10)% across the surveyed regions was measured, which is compatible with an empirical estimate of 0.825% computed from known material properties. Higher-granularity maps of the fractional radiation length were produced for both rectangular regions and regions of uniform material composition. The results bode well for the CMS Phase-2 upgrade modules, which will play a key role in the minimisation of the material budget of the upgraded detector
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