System and Process for agglomeration and processing of carbonaceous fines and dust

A system and process for agglomerating and processing carbonaceous fines is provided. The process comprises powdering the carbonaceous fines, mixing the powdered carbonaceous fines with an organic liquid creating a slurry, adding a predetermined amount of an aqueous electrolyte to the slurry creating agglomerated particles, settling the large agglomerated particles resulting in a settled mixture of agglomerated coal fines and reagent liquor, and separating the agglomerated coal fines from the reagent liquor

Immersive Episodic Memory Assessment with 360\ub0 Videos: The Protocol and a Case Study

Episodic memory has been conceptualized as the memory for personal events with specific spatiotemporal components. The assessment of episodic memory is usually conducted by means of verbal recall tasks, in which the individual is required to repeat what (s)he remembers from a previously presented verbal material (either single words or a brief story). However, the need of a more ecological approach to memory assessment led researchers to investigate the potential use of 360\ub0 videos as a suitable tool to present real life scenes to be remembered. The present study presents the protocol of the assessment of episodic memory employing five 360\ub0 video that represent interpersonal, emotional experiences known to be altered in psychopathological conditions. Furthermore, a case study in which the assessment protocol is applied to a patient with Borderline Personality Disorder is described. The results of the case study seem to indicate that our 360\ub0 videos are able to detect anomalies in remembering the behaviors displayed, the connected emotion together with details regarding the \u201cwhere\u201d and \u201cwhen\u201d components of the episodic recall

Discovery of potent and selective histamine H3 receptor inverse agonists based on the 3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one scaffold

A novel series of potent histamine H(3) receptor inverse agonists based on the 3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one scaffold has been discovered. Several compounds display high selectivity over other histamine receptor subtypes and have favorable physicochemical properties, low potential for CYP450 enzyme inhibition and high metabolic stability in microsomal preparations. (R)-2-Cyclopropylmethyl-8-(1-isopropyl-piperidin-4-yloxy)-3-methyl-3,4-dih ydro-2H-pyrazino[1,2-a]indol-1-one (8t) showed good in vivo efficacy after per os application in an acute rat dipsogenia model of water intake