111 research outputs found

    Understanding the global patterns of Venezuelan migration:determinants of an expanding diaspora

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    The economic, political and humanitarian crisis in Venezuela intensified since 2015 and has led to the largest migration crisis in the region’s modern history. In parallel, the composition of the major destination countries has changed fundamentally. This paper investigates the factors determining the choice of destination country of Venezuelan migrants in the pre- and post-2015 period. Exploiting the United Nations migration dataset (for 230 countries from 1990 to 2017), we apply a Poisson Pseudo-Maximum Likelihood (PPML) estimator to a modified gravity model of migration. The results suggest that Venezuelans were generally choosing a certain destination country based on economic criteria in times of relative stability (1990 to 2015). However, this determinant loses its importance during times of crisis (2015 to 2017), when Venezuelans were primarily immigrating to geographically proximate nations. Consistently for both periods Venezuelans appear to migrate in larger numbers to destinations with an already established network of compatriots.</p

    Minimal versus conventional cardiopulmonary bypass: assessment of intraoperative myocardial damage in coronary bypass surgery

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    Objective: Minimal extracorporeal circulation (mini-ECC) is a new technology, consisting of a centrifugal pump, an oxygenator, and a modified suction system. The main advantage of mini-ECC is the reduction of tubing length (reduction of the priming volume). Additional beneficial effects are a decrease of coagulation cascade and a reduction of blood transfusion in patients undergoing coronary artery bypass grafting (CABG) surgery. We compared the intraoperative and early postoperative myocardial damage and outcome of patients who underwent CABG surgery with conventional cardiopulmonary bypass (CPB) or mini-ECC. Methods: One hundred and thirty-six consecutive patients who underwent isolated CABG surgery at our institution were prospectively studied. Fifty-four patients (39.7%) were operated with mini-ECC. Patient characteristics were similar in both groups. The most interesting intraoperative details as well as in-hospital outcome were assessed. Results: There was no difference in mortality between the two groups. Cross-clamping time was similar in both groups (p = 0.07). Defibrillation was required in one patient in the mini-ECC group (1.9%) and in 38 patients (46.3%) in the CPB group (p < 0.001). In the mini-ECC group, the requirement of inotropic support and incidence of atrial fibrillation was significantly lower than in the CPB group. Postoperative creatine kinase isoenzyme MB (CK-MB) and cardiac Troponin I (cTnI) were significantly lower in the mini-ECC group (p < 0.05). Duration of ventilation, length of stay in the intensive care unit and total hospitalization time were significantly shorter in patients operated with mini-ECC (p < 0.05). Conclusion: Mini-ECC is a safe procedure and is followed by a diminished release of CK-MB and cTnI than after CPB. Postoperative recovery is accelerated following mini-ECC and there is a significantly lower incidence of postoperative atrial fibrillatio

    Successful Treatment of Disseminated Nocardiosis Complicated by Cerebral Abscess with Ceftriaxone and Amikacin: Case Report

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    We report the case of an 85-year-old female patient who suffered from disseminated Nocardia asteroides infection complicated by a cerebral abscess. Treatment with amikacin for 2 weeks and ceftriaxone for 6 weeks led to complete recovery, and there was no recurrence of disease over a follow-up period of 12 months after therapy. The use of ceftriaxone in combination with amikacin might significantly shorten the duration of treatment for patients with disseminated nocardiosis. This combination of antibiotics merits further investigation with use of a larger sample of patient

    Fecal Glucocorticoid Measurements and Their Relation to Rearing, Behavior, and Environmental Factors in the Population of Pileated Gibbons ( Hylobates pileatus ) Held in European Zoos

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    Pileated gibbons (Hylobates pileatus) are rated as endangered according to the International Union of Conservation of Nature (IUCN) Red List. The captive population suffers from poor breeding success and is threatened to become overaged. Although several factors are likely to contribute to the poor breeding success, one in particular may be chronic stress associated with prolonged periods of high glucocorticoid (GC) output. We investigated fecal GC levels of pileated gibbons (Hylobates pileatus) and their relationship to specific life-history variables and environmental factors. After validation of an enzyme immunoassay for the measurement of 5-reduced 3α,11β-dihydroxy cortisol metabolites to assess GC output reliably in pileated gibbons, we collected fecal samples over several days from all 36 European adult pileated gibbons located in 11 institutions and compared GC levels to intrinsic individual parameters, husbandry, behavior, and breeding history. Age, sex, and origin (wild vs. captive born) had no effect on GC levels. However, unnaturally reared gibbons had higher GC levels and showed more behavioral abnormalities than parent-reared individuals. Further, nonreproducing gibbons living in a pair without infants had higher GC concentrations than gibbons living in a family, bachelor group, or as singletons. With respect to environmental factors, a large size of the inside enclosure and the existence of visual protection from visitors was associated with lower fecal GC output. The data indicate that rearing and housing conditions appear to correlate to GC levels in pileated gibbons housed under captive conditions. It is hoped this knowledge will support the future management of the species in captivity and thus lead to a more successful breeding of this endangered primat

    Practice centers - School-based teacher education in a collaborative space between schools and university

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    Mit Praxiszentren erprobt die Pädagogische Hochschule Zürich neue Wege der Zusammenarbeit mit dem Schulfeld in der berufspraktischen Ausbildung von Lehrpersonen für die Volksschule. In diesem Beitrag werden die Ausgangslage, theoretische und empirische Grundlagen und das Konzept der Praxiszentren mit den Funktionen der Ausbildungsbeteiligten beschrieben. Es wird ausgeführt, wie Praxiszentren als kooperative Räume der Lehrpersonenbildung ausgestaltet werden. Am Ende der vierjährigen Projektlaufzeit sind 16 Praxiszentren operativ und beteiligen sich voraussichtlich am Nachfolgemodell. Erfahrungen aus der Projektphase zeigen, dass die intensivere und verbindlichere Zusammenarbeit an den Schulen auf grosse Zustimmung stösst. Auch ist den Beteiligten deutlich bewusst geworden, dass berufspraktische Lehrpersonenbildung als Element der Vorbereitung auf einen erfolgreichen Berufseinstieg nur gemeinsam von Hochschule, Schulfeld und Bildungsverwaltung zu bewältigen ist. Projekterfahrungen und Erkenntnisse aus der Begleitforschung ermöglichen eine Weiterentwicklung der Konzeption der berufspraktischen Ausbildung in Kooperation mit allen relevanten Gruppen von Akteurinnen und Akteuren. (DIPF/Orig.)With practice centers, the Zurich University of Teacher Education was testing new ways of collaboration with schools for the practice-based education of teachers for elementary school. This article presents the background, the theoretical and the empirical foundations, the concept of practice centers, and the roles and functions of the educators involved. We explain how practice centers are designed as individual collaborative spaces for teacher training within clusters of schools. At the end of the four-year project period, 16 practice centers are operational and will participate in a successor model. Experience from the project phase shows that the more intensive and binding continuous collaboration at the schools meets with great approval from all participants. The stakeholders have also become clearly aware that practical teacher training as an element of the preparation for successful career entry can only be provided jointly by the university, the schools, and the education administration. Project experiences and findings from accompanying research form the basis for the further development of the concept in collaboration with relevant stakeholder groups. (DIPF/Orig.

    Praxiszentren – Berufspraktische Lehrpersonenbildung im kooperativen Raum zwischen Schulfeld und Hochschule

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    Mit Praxiszentren erprobt die Pädagogische Hochschule Zürich neue Wege der Zusammenarbeit mit dem Schulfeld in der berufspraktischen Ausbildung von Lehrpersonen für die Volksschule. In diesem Beitrag werden die Ausgangslage, theoretische und empirische Grundlagen und das Konzept der Praxiszentren mit den Funktionen der Ausbildungsbeteiligten beschrieben. Es wird ausgeführt, wie Praxiszentren als kooperative Räume der Lehrpersonenbildung ausgestaltet werden. Am Ende der vierjährigen Projektlaufzeit sind 16 Praxiszentren operativ und beteiligen sich voraussichtlich am Nachfolgemodell. Erfahrungen aus der Projektphase zeigen, dass die intensivere und verbindlichere Zusammenarbeit an den Schulen auf grosse Zustimmung stösst. Auch ist den Beteiligten deutlich bewusst geworden, dass berufspraktische Lehrpersonenbildung als Element der Vorbereitung auf einen erfolgreichen Berufseinstieg nur gemeinsam von Hochschule, Schulfeld und Bildungsverwaltung zu bewältigen ist. Projekterfahrungen und Erkenntnisse aus der Begleitforschung ermöglichen eine Weiterentwicklung der Konzeption der berufspraktischen Ausbildung in Kooperation mit allen relevanten Gruppen von Akteurinnen und Akteuren

    Methodological considerations in the analysis of fecal glucocorticoid metabolites in tufted capuchins (Cebus apella)

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    Analysis of fecal glucocorticoid (GC) metabolites has recently become the standard method to monitor adrenocortical activity in primates noninvasively. However, given variation in the production, metabolism, and excretion of GCs across species and even between sexes, there are no standard methods that are universally applicable. In particular, it is important to validate assays intended to measure GC production, test extraction and storage procedures, and consider the time course of GC metabolite excretion relative to the production and circulation of the native hormones. This study examines these four methodological aspects of fecal GC metabolite analysis in tufted capuchins (Cebus apella). Specifically, we conducted an adrenocorticotrophic hormone (ACTH) challenge on one male and one female capuchin to test the validity of four GC enzyme immunoassays (EIAs) and document the time course characterizing GC me- tabolite excretion in this species. In addition, we compare a common field-friendly technique for extracting fecal GC metabolites to an established laboratory extraction methodology and test for effects of storing “field extracts” for up to 1 yr. Results suggest that a corticosterone EIA is most sensitive to changes in GC production, provides reliable measures when extracted according to the field method, and measures GC metabolites which remain highly stable after even 12 mo of storage. Further, the time course of GC metabolite excretion is shorter than that described yet for any primate taxa. These results provide guidelines for studies of GCs in tufted capuchins, and underscore the importance of validating methods for fecal hormone analysis for each species of interest

    The 24/7 approach to promoting optimal welfare for captive wild animals

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    We have an ethical responsibility to provide captive animals with environments that allow them to experience good welfare. Husbandry activities are often scheduled for the convenience of care staff working within the constraints of the facility, rather than considering the biological and psychological requirements of the animals themselves. The animal welfare 24/7 across the lifespan concept provides a holistic framework to map features of the animal’s life cycle, taking into account their natural history, in relation to variations in the captive environment, across day and night, weekdays, weekends, and seasons. In order for animals to have the opportunity to thrive, we argue the need to consider their lifetime experience, integrated into the environments we provide, and with their perspective in mind. Here, we propose a welfare assessment tool based upon 14 criteria, to allow care staff to determine if their animals’ welfare needs are met. We conclude that animal habitat management will be enhanced with the use of integrated technologies that provide the animals with more opportunities to engineer their own environments, providing them with complexity, choice and control

    Individual, social, and environmental factors affecting salivary and fecal cortisol levels in captive pied tamarins (Saguinus bicolor)

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    This is the peer reviewed version of the following article: Price, E., Coleman, R., Ahsmann, J., Glendewar, G., Hunt, J., Smith, T. & Wormell, D. (2019). Individual, social, and environmental factors affecting salivary and fecal cortisol levels in captive pied tamarins (Saguinus bicolor). American Journal of Primatology, 81(8), which has been published in final form at https://doi.org/10.1002/ajp.23033. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-ArchivingPied tamarins (Saguinus bicolor) are endangered New World primates, and in captivity appear to be very susceptible to stress. We measured cortisol in 214 saliva samples from 36 tamarins and in 227 fecal samples from 27 tamarins, and investigated the effects of age, sex, pregnancy, rearing history, social status, weight, group composition, and enclosure type using generalized linear mixed models. There was no effect of age on either fecal or salivary cortisol levels. Female pied tamarins in late pregnancy had higher fecal cortisol levels than those in early pregnancy, or nonpregnant females, but there was no effect of pregnancy on salivary cortisol. Females had higher salivary cortisol levels than males, but there was no effect of rearing history. However, for fecal cortisol, there was an interaction between sex and rearing history. Hand‐reared tamarins overall had higher fecal cortisol levels, but while male parent‐reared tamarins had higher levels than females who were parent‐ reared, the reverse was true for hand‐reared individuals. There was a trend towards lower fecal cortisol levels in subordinate individuals, but no effect of status on salivary cortisol. Fecal but not salivary cortisol levels declined with increasing weight. We found little effect of group composition on cortisol levels in either saliva or feces, suggesting that as long as tamarins are housed socially, the nature of the group is of less importance. However, animals in off‐show enclosures had higher salivary and fecal cortisol levels than individuals housed on‐show. We suggest that large on‐show enclosures with permanent access to off‐exhibit areas may compensate for the effects of visitor disturbance, and a larger number of tamarins of the same species housed close together may explain the higher cortisol levels found in tamarins living in off‐show accommodation, but further research is needed
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