A Bulk-Parallel Priority Queue in External Memory with STXXL

We propose the design and an implementation of a bulk-parallel external memory priority queue to take advantage of both shared-memory parallelism and high external memory transfer speeds to parallel disks. To achieve higher performance by decoupling item insertions and extractions, we offer two parallelization interfaces: one using "bulk" sequences, the other by defining "limit" items. In the design, we discuss how to parallelize insertions using multiple heaps, and how to calculate a dynamic prediction sequence to prefetch blocks and apply parallel multiway merge for extraction. Our experimental results show that in the selected benchmarks the priority queue reaches 75% of the full parallel I/O bandwidth of rotational disks and and 65% of SSDs, or the speed of sorting in external memory when bounded by computation.Comment: extended version of SEA'15 conference pape

Bioarchaeological and palaeogenomic portrait of two Pompeians that died during the eruption of Vesuvius in 79 AD

The archaeological site of Pompeii is one of the 54 UNESCO World Heritage sites in Italy, thanks to its uniqueness: the town was completely destroyed and buried by a Vesuvius’ eruption in 79 AD. In this work, we present a multidisciplinary approach with bioarchaeological and palaeogenomic analyses of two Pompeian human remains from the Casa del Fabbro. We have been able to characterize the genetic profle of the frst Pompeian’ genome, which has strong afnities with the surrounding central Italian population from the Roman Imperial Age. Our fndings suggest that, despite the extensive connection between Rome and other Mediterranean populations, a noticeable degree of genetic homogeneity exists in the Italian peninsula at that time. Moreover, palaeopathological analyses identifed the presence of spinal tuberculosis and we further investigated the presence of ancient DNA from Mycobacterium tuberculosis. In conclusion, our study demonstrates the power of a combined approach to investigate ancient humans and confrms the possibility to retrieve ancient DNA from Pompeii human remains. Our initial fndings provide a foundation to promote an intensive and extensive paleogenetic analysis in order to reconstruct the genetic history of population from Pompeii, a unique archaeological site

The Political Legacy of Entertainment TV

We study the political impact of commercial television in Italy exploiting the staggered introduction of Berlusconi's private TV network, Mediaset, in the early 1980s. We find that individuals with early access to Mediaset all-entertainment content were more likely to vote for Berlusconi's party in 1994, when he first ran for office. The effect persists for five elections and is driven by heavy TV viewers, namely the very young and the elderly. Regarding possible mechanisms, we find that individuals exposed to entertainment TV as children were less cognitively sophisticated and civic-minded as adults, and ultimately more vulnerable to Berlusconi's populist rhetoric. © 2019 AE

Formación de megacristales de feldespato potásico en el sector sur del batolito Cerro Aspero-Alpa Corral (32°40'S y 64°50'W), Sierras Pampeanas, Córdoba, Argentina

The surrounding rocks of studied area are composed by a metamorphic sequence which includes gneisses, schists, amphibolites, marbles and heterogeneous migmatites in non-conformity intruded by a granitic pluton. All this sequence is dated as having late-Precambric to mid-Paleozoic age.Three facies, mostly of monzogranitic composition, were identified. This study focuses on the porphiric facies; detailed petroestructural studies being performed, the orientation of large microcline crystal and associated microgranular enclaves being measured.Different primary flow directions were determined with track variation of microcline megacrystal and enclaves from subvertical to nearly horizontal positions.These changes have been interpreted as a convective system within the pluton.The presence of a marked planar fabric in microcline megacrystals along with phenomena such a size-variation of crystal, synneusis, crystal trending at the enclave's border and crystal accumulation, proves their early magmatic origin. The enclaves show a cinematic of deformation produced by simple shear.El entorno encajante de la zona estudiada está integrado por una secuencia metamórfica que incluye gneises, esquistos, anfibolitas, calizas cristalinas y migmatitas heterogéneas, intruidas discordantemente por el plutón granítico. A este conjunto puede asignársele una edad precámbrica superior-paleozoica media.Se identificaron tres facies, en su mayoría de composición monzogranítica, diques micrograníticos a aplíticos y enclaves. En este trabajo se pone énfasis en la facies porfiroide efectuándose estudios petroestructurales de detalle, tomando como indicadores la orientación de los grandes cristales de microclina y enclaves microgranulares asociados.Se determinaron distintas direcciones de flujo primario con variaciones en la trayectoria de los megacristales de microclina y enclaves desde posiciones subverticales hasta aproximadamente horizontales. Estos cambios han sido interpretados como un sistema convectivo dentro del plutón.La presencia de una marcada fábrica planar en los megacristales de microclina, conjuntamente con fenómenos de gradaciones en el tamaño de cristales, sineusis, alineaciones en los bordes de enclaves y aglomeraciones de cristales evidencian su origen temprano magmático. Los enclaves muestran una cinemática de deformación producida por cizalla simple

Granitos anatécticos de las Sierras Pampeanas de Córdoba (Argentina): edades U-Pb SHRIMP y estudio LAICP- MS de elementos traza en circón de metamorfismo y cristalización diacrónicos

In this contribution we present new U-Pb SHRIMP ages and in situ LA-ICP-MS trace element geochemistry of zircon crystals from the Río de los Sauces anatectic granite, Córdoba, Argentina. Notable difference in texture and composition allowed us to identify two zircon populations in a single granite sample that are interpreted as reflecting metamorphic and igneous origins. Zircons regarded as restitic crystals entrained during the melt segregation yielded a slightly older concordia age of 537.1 ± 4.8 Ma (2σ) than those interpreted as igneous, dated at 529 ± 6 (2σ) Ma. Inherited metamorphic zircons are interpreted to represent solid-state growth during high temperature metamorphism of the Pampean orogeny at the onset of the anatexis or metamorphic peak. By contrast, igneous zircons would record the crystallization age of Zr within the Río de los Sauces granite. The textural, compositional and geochronological data of both zircon populations suggest that the inception of the anatexis, the melt segregation and crystallization occurred during a short period of time of 8 myEn este trabajo se aportan nuevos datos de edades U-Pb SHRIMP y análisis in situ LA-ICP-MS de elementos traza de circones provenientes del granito Río de los Sauces, Córdoba, Argentina. A partir de marcadas diferencias texturales y composicionales se pudieron identificar dos poblaciones de circones en una misma muestra del granito, las cuales sugieren orígenes metamórficos e ígneos. Las edades concordia obtenidas en los circones metamórficos e ígneos fueron de 537,1 ± 4,8 Ma (2σ) y 529 ± 6 (2σ) Ma, respectivamente. Se interpreta que los circones metamórficos representan el crecimiento en estado sólido durante el metamorfismo de alta temperatura de la orogenia Pampeana, durante el inicio o el clímax de la anatexia. Por su parte, las edades de los circones ígneos representan la edad de cristalización del granito Río de los Sauces. Los datos texturales, composicionales y geocronológicos de ambas poblaciones de circones sugieren que el inicio de la anatexia, la segregación del fundido y la cristalización ocurrieron durante un periodo breve de tiempo de 8 ma

Fate of Salmonella enterica Typhimurium and Listeria monocytogenes in Black Soldier Fly (Hermetia illucens) Larvae Reared on Two Artificial Diets

Ensuring food security is one of the main challenges facing the world over the next 30 years. There is, thus, an urgent need to significantly increase the supply of sustainable protein that can be transformed into animal feed. Proteins from insects offer a valuable alternative. This article presents the results of challenge tests conducted to investigate the dynamics of the microbial load of Salmonella enterica Typhimurium and Listeria monocytogenes in black soldier fly (Hermetia illucens) larvae grown on contaminated substrates. Four separate challenge tests were performed on two substrates: the Gainesville diet and a homemade diet. The challenge test procedure was carried out in accordance with ISO/DIS 20976-2 (under development). The results of this study show that, when grown on contaminated substrates, BSF larvae do not eliminate Salmonella Typhimurium or L. monocytogenes, but can reduce their microbial load. Sanitation processes downstream of the breeding of BSF larvae are, however, required to reduce the microbiological risks of this novel food

Biofortification of selenium in black soldier fly (Hermetia illucens) prepupae reared on seaweed or selenium enriched substrates

Selenium (Se) is an essential trace element for livestock. The element can be supplemented to feed in inorganic or organic Se forms, where the chemical form in the diet affects the accumulation of Se in animal tissues. Insects are known to be natural bioaccumulators of different nutrients, but no studies have so far looked up on the capacity of insects to be biofortified with Se, as a potential future source for Se in feed. In this study, black soldier fly (BSF, Hermetia illucens) larvae were reared on three different substrates: (1) a control substrate (CTR diet) of plant-ingredients (Gainesville diet); (2) Ascophyllum nodosum diet (AN30%), with 30% substitution of the alfalfa meal with the brown algae; and (3) a Se diet, where the CTR diet was fortified with 0.3 mg/kg of Se. All experiments were carried out under dark condition, at 25 °C with 70% relative humidity for two weeks, and the final BSF prepupae were analysed for Se, metals and minerals, and Se species. The mean total Se content in the prepupae reared on Se dietary group was over five times higher compared to the CTR group, whereas lower Se levels were detected in AN30% dietary group. Se speciation analyses showed that organic selenomethionine (SeMet) was the major Se species present, both in CTR and AN30% group. For the Se group, SeMet was accounting for 54% of the total Se. The levels of SeMet were higher in the Se group compared to the CTR group, indicating that BSF prepupae are able to convert inorganic Se to organic Se. The overall results show that the substrates hereby studied affect the total Se and Se species, as well as the levels of other elements, in the BSF prepupae.publishedVersio

Mucosa associated lymphoid tissue lymphoma presenting within a solitary anti-mesenteric dilated segment of ileum: a case report

<p>Abstract</p> <p>Introduction</p> <p>Mucosa associated lymphoid tissue (MALT) lymphoma is the third most common non-Hodgkin's lymphoma subtype. Clinical presentation is often insidious as a low-grade lesion and disease tends to remain localised for a long period of time. Ileal involvement is rare and presentation within an area of focal anti-mesenteric ileal wall dilation simulating a large diverticulum has not been reported.</p> <p>Case presentation</p> <p>A 59-year-old man of Caucasian origin presented to a general surgical outpatients clinic with an 18-month history of intermittent upper abdominal pain following meals. Following normal gastroscopy and abdominal ultrasound, a focally dilated segment of ileum was seen on computed tomography and further clarified by barium investigation. Histology of this segment demonstrated MALT lymphoma of the small bowel.</p> <p>Conclusion</p> <p>A solitary focally dilated segment of ileal wall may be neoplastic in nature and surgical resection needs to be considered.</p

Network sensitivity of systemic risk

A growing body of studies on systemic risk in financial markets has emphasized the key importance of taking into consideration the complex interconnections among financial institutions. Much effort has been put into modeling the contagion dynamics of financial shocks and into assessing the resilience of specific financial markets, either using real network data, reconstruction techniques or simple toy networks. Here, we address the more general problem of how shock propagation dynamics depend on the topological details of the underlying network. To this end, we consider different realistic network topologies, all consistent with balance sheet information obtained from real data on financial institutions. In particular, we consider networks of varying density and with different block structures. In addition, we diversify in the details of the shock propagation dynamics. We confirm that the systemic risk properties of a financial network are extremely sensitive to its network features. Our results can aid in the design of regulatory policies to improve the robustness of financial markets