611 research outputs found

    An acceptor-substrate binding site determining glycosyl transfer emerges from mutant analysis of a plant vacuolar invertase and a fructosyltransferase

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    Glycoside hydrolase family 32 (GH32) harbors hydrolyzing and transglycosylating enzymes that are highly homologous in their primary structure. Eight amino acids dispersed along the sequence correlated with either hydrolase or glycosyltransferase activity. These were mutated in onion vacuolar invertase (acINV) according to the residue in festuca sucrose:sucrose 1-fructosyltransferase (saSST) and vice versa. acINV(W440Y) doubles transferase capacity. Reciprocally, saSST(C223N) and saSST(F362Y) double hydrolysis. SaSST(N425S) shows a hydrolyzing activity three to four times its transferase activity. Interestingly, modeling acINV and saSST according to the 3D structure of crystallized GH32 enzymes indicates that mutations saSST(N425S), acINV(W440Y), and the previously reported acINV(W161Y) reside very close together at the surface in the entrance of the active-site pocket. Residues in- and outside the sucrose-binding box determine hydrolase and transferase capabilities of GH32 enzymes. Modeling suggests that residues dispersed along the sequence identify a location for acceptor-substrate binding in the 3D structure of fructosyltransferases

    Observation of Bs-Bsbar Oscillations

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    We report the observation of Bs-Bsbar oscillations from a time-dependent measurement of the Bs-Bsbar oscillation frequency Delta ms. Using a data sample of 1 fb^-1 of p-pbar collisions at sqrt{s}=1.96 TeV collected with the CDF II detector at the Fermilab Tevatron, we find signals of 5600 fully reconstructed hadronic Bs decays, 3100 partially reconstructed hadronic Bs decays, and 61500 partially reconstructed semileptonic Bs decays. We measure the probability as a function of proper decay time that the Bs decays with the same, or opposite, flavor as the flavor at production, and we find a signal for Bs-Bsbar oscillations. The probability that random fluctuations could produce a comparable signal is 8 X 10^-8, which exceeds 5 sigma significance. We measure Delta ms = 17.77 +- 0.10 (stat) +- 0.07 (syst) ps^-1 and extract |Vtd/Vts| = 0.2060 +- 0.0007 (exp) + 0.0081 - 0.0060 (theor).Comment: 9 pages, 5 figures, submitted to Physical Review Letter

    Limits on Anomalous Triple Gauge Couplings in ppbar Collisions at sqrt{s}=1.96 TeV

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    We present a search for anomalous triple gauge couplings (ATGC) in WW and WZ boson production. The boson pairs are produced in ppbar collisions at sqrt{s}=1.96 TeV, and the data sample corresponds to 350 pb-1 of integrated luminosity collected with the CDF II detector at the Fermilab Tevatron. In this search one W decays to leptons, and the other boson (W or Z) decays hadronically. Combining with a previously published CDF measurement of Wgamma boson production yields ATGC limits of -0.18 < lambda < 0.17 and -0.46 < Delta kappa < 0.39 at the 95% confidence level, using a cut-off scale Lambda=1.5 TeV.Comment: 7 pages, 3 figures. Submitted to Phys. Rev.

    Search for Pair Production of Scalar Top Quarks Decaying to a tau Lepton and a b Quark in ppbar Collisions at sqrt{s}=1.96 TeV

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    We search for pair production of supersymmetric top quarks (~t_1), followed by R-parity violating decay ~t_1 -> tau b with a branching ratio beta, using 322 pb^-1 of ppbar collisions at sqrt{s}=1.96 TeV collected by the CDF II detector at Fermilab. Two candidate events pass our final selection criteria, consistent with the standard model expectation. We set upper limits on the cross section sigma(~t_1 ~tbar_1)*beta^2 as a function of the stop mass m(~t_1). Assuming beta=1, we set a 95% confidence level limit m(~t_1)>153 GeV/c^2. The limits are also applicable to the case of a third generation scalar leptoquark (LQ_3) decaying LQ_3 -> tau b.Comment: 7 pages, 2 eps figure

    Observation and Mass Measurement of the Baryon Ξb\Xi^-_b

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    We report the observation and measurement of the mass of the bottom, strange baryon Ξb\Xi^-_b through the decay chain ΞbJ/ψΞ\Xi^-_b \to J/\psi \Xi^-, where J/ψμ+μJ/\psi \to \mu^+ \mu^-, ΞΛπ\Xi^- \to \Lambda \pi^-, and Λpπ\Lambda \to p \pi^-. Evidence for observation is based on a signal whose probability of arising from the estimated background is 6.6 x 10^{-15}, or 7.7 Gaussian standard deviations. The Ξb\Xi^-_b mass is measured to be 5792.9±2.55792.9\pm 2.5 (stat.) ±1.7\pm 1.7 (syst.) MeV/c2c^2.Comment: Minor text changes for the second version. Accepted by Phys. Rev. Let

    Polarizations of J/psi and psi(2S) Mesons Produced in ppbar Collisions at 1.96 TeV

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    We have measured the polarizations of \jpsi and \psiprime mesons as functions of their transverse momentum \pt when they are produced promptly in the rapidity range y<0.6|y|<0.6 with \pt \geq 5 \pgev. The analysis is performed using a data sample with an integrated luminosity of about 800 \ipb collected by the CDF II detector. For both vector mesons, we find that the polarizations become increasingly longitudinal as \pt increases from 5 to 30 \pgev. These results are compared to the predictions of nonrelativistic quantum chromodynamics and other contemporary models. The effective polarizations of \jpsi and \psiprime mesons from BB-hadron decays are also reported.Comment: 8 pages, 7 figures, published in Physical Review Letter

    Measurement of the Top-Quark Mass in All-Hadronic Decays in p pbar Collisions at CDF II

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    We present a measurement of the top-quark mass, MtopM_{\mathrm{top}}, in the all-hadronic decay channel ttˉW+bWbˉq1qˉ2bq3qˉ4bˉt\bar{t} \to W^+b W^- \bar{b} \to q_1\bar{q}_2 b q_3 \bar{q}_4 \bar{b}. The analysis is performed using 310 pb1^{-1} of s\sqrt{s}=1.96 TeV ppˉp\bar{p} collisions collected with the CDF II detector using a multi-jet trigger. The mass measurement is based on an event-by-event likelihood which depends on both the sample purity and the value of the top-quark mass, using 90 possible jet-to-parton assignments in the six-jet final state. The joint likelihood of 290 selected events yields a value of MtopM_{\mathrm{top}}=177.1 ±\pm 4.9 (stat.) ±\pm 4.7 (syst.) GeV/c2c^2.Comment: 7 pages, 2 figures and 1 table, Submitted to Phys. Rev. Let

    Search for Third Generation Vector Leptoquarks in p anti-p Collisions at sqrt(s) = 1.96 TeV

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    We describe a search for a third generation vector leptoquark (VLQ3) that decays to a b quark and tau lepton using the CDF II detector and 322 pb^(-1) of integrated luminosity from the Fermilab Tevatron. Vector leptoquarks have been proposed in many extensions of the standard model (SM). Observing a number of events in agreement with SM expectations, assuming Yang-Mills (minimal) couplings, we obtain the most stringent upper limit on the VLQ3 pair production cross section of 344 fb (493 fb) and lower limit on the VLQ3 mass of 317 GeV/c^2 (251 GeV/c^2) at 95% C.L.Comment: 7 pages, 2 figures, submitted to PR

    Precise measurement of the top quark mass in the lepton+jets topology at CDF II

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    We present a measurement of the mass of the top quark from proton-antiproton collisions recorded at the CDF experiment in Run II of the Fermilab Tevatron. We analyze events from the single lepton plus jets final state (ttˉW+bWbˉlνbqqˉbˉt\bar t\to W^+bW^-\bar b\to l\nu b q \bar q'\bar b). The top quark mass is extracted using a direct calculation of the probability density that each event corresponds to the ttˉt\bar t final state. The probability is a function of both the mass of the top quark and the energy scale of the calorimeter jets, which is constrained {\it in situ} by the hadronic WW boson mass. Using 167 events observed in 955 pb1^{{-}1} of integrated luminosity, we achieve the single most precise measurement of the top quark mass, 170.8 ±\pm 2.2 (stat.) ±\pm 1.4 (syst.) GeV/c2c^2.Comment: accepted by Phys. Rev. Let

    Analysis of the Quantum Numbers JPCJ^{PC} of the X(3872) Particle

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    We present an analysis of angular distributions and correlations of the X(3872) particle in the exclusive decay mode X(3872)->J/psi pi+ pi- with J/psi->mu+ mu-. We use 780 pb -1 of data from ppbar collisions at sqrt{s} = 1.96 TeV collected with the CDF II detector at the Fermilab Tevatron. We derive constraints on spin, parity, and charge conjugation parity of the X(3872) particle by comparing measured angular distributions of the decay products with predictions for different JPC hypotheses. The assignments JPC = 1++ and 2-+ are the only ones consistent with the data.Comment: update to journal versio
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