856 research outputs found
Detecting and Modeling the Changes of Land Use/Cover for Land Use Planning in Da Nang City, Viet Nam
The geometrical accuracy of georeferenced digital surfacemodels (DTM) obtained fromimages captured bymicro-UAVs and processed by using structure frommotion (SfM) photogrammetry depends on several factors, including flight design, camera quality, camera calibration, SfM algorithms and georeferencing strategy. This paper focusses on the critical role of the number and location of ground control points (GCP) used during the georeferencing stage. A challenging case study involving an area of 1200+ ha, 100+ GCP and 2500+ photos was used. Three thousand, four hundred and sixty-five different combinations of control points were introduced in the bundle adjustment, whilst the accuracy of the model was evaluated using both control points and independent check points. The analysis demonstrates how much the accuracy improves as the number of GCP points increases, as well as the importance of an even distribution, how much the accuracy is overestimated when it is quantified only using control points rather than independent check points, and how the ground sample distance (GSD) of a project relates to the maximum accuracy that can be achieved
Causality and Localization Operators
The evolution of the expectation values of one and two points scalar field
operators and of positive localization operators, generated by an istantaneous
point source is non local. Non locality is attributed either to zero point
vacuum fluctuations, or to non local operations or to the microcausality
principle being no satisfied.Comment: 10 pages; submitted to Physics Letters
A rare case of renal oncocytoma associated with erythrocytosis: case report
BACKGROUND: Oncocytomas are benign tumors of the kidney that are usually diagnosed postoperatively due to differential diagnostic problems from renal cell carcinoma. Although the latter are neoplasms that have been associated with erythrocytosis in 3.5% of cases, there are no reports in the literature about a similar occurrence in oncocytomas. CASE PRESENTATION: In this case report we present a unique case of a right lower pole oncocytoma associated with erythrocytosis. Erythrocytosis subsided after partial nephrectomy. CONCLUSION: Erythrocytosis can sometimes occur in association with renal oncocytomas
Follicular Dendritic Cell Sarcoma of the Tonsil
Follicular dendritic cell sarcoma (FDCS) is unusual, and those with an extranodal origin in the head and neck region are extremely rare. To date, no cases of tumors featuring the characteristics of follicular dendritic cells were reported in Korea. We report a new case of FDCS of the tonsils in a 65-year-old man. A diagnostic tonsillectomy was performed. Based on histopathologic and immunohistochemical findings, the patient was diagnosed with FDCS. Adjuvant radiotherapy was performed due to a high mitotic count. The patient survived with a 2-year disease free period. The differential diagnosis of a tonsillar mass must include FDCS. In cases in which FDCS is suspected on histopathologic examination, an immunohistochemical study is essential for the diagnosi
mRNA transcript quantification in archival samples using multiplexed, color-coded probes
Background: A recently developed probe-based technology, the NanoString nCounter™ gene expression system, has been shown to allow accurate mRNA transcript quantification using low amounts of total RNA. We assessed the ability of this technology for mRNA expression quantification in archived formalin-fixed, paraffin-embedded (FFPE) oral carcinoma samples.
Results: We measured the mRNA transcript abundance of 20 genes (COL3A1, COL4A1, COL5A1, COL5A2, CTHRC1, CXCL1, CXCL13, MMP1, P4HA2, PDPN, PLOD2, POSTN, SDHA, SERPINE1, SERPINE2, SERPINH1, THBS2, TNC, GAPDH, RPS18) in 38 samples (19 paired fresh-frozen and FFPE oral carcinoma tissues, archived from 1997-2008) by both NanoString and SYBR Green I fluorescent dye-based quantitative real-time PCR (RQ-PCR). We compared gene expression data obtained by NanoString vs. RQ-PCR in both fresh-frozen and FFPE samples. Fresh-frozen samples showed a good overall Pearson correlation of 0.78, and FFPE samples showed a lower overall correlation coefficient of 0.59, which is likely due to sample quality. We found a higher correlation coefficient between fresh-frozen and FFPE samples analyzed by NanoString (r = 0.90) compared to fresh-frozen and FFPE samples analyzed by RQ-PCR (r = 0.50). In addition, NanoString data showed a higher mean correlation (r = 0.94) between individual fresh-frozen and FFPE sample pairs compared to RQ-PCR (r = 0.53).
Conclusions: Based on our results, we conclude that both technologies are useful for gene expression quantification in fresh-frozen or FFPE tissues; however, the probe-based NanoString method achieved superior gene expression quantification results when compared to RQ-PCR in archived FFPE samples. We believe that this newly developed technique is optimal for large-scale validation studies using total RNA isolated from archived, FFPE samples
Polymorphous low-grade adenocarcinoma of the tongue: a case report
<p>Abstract</p> <p>Introduction</p> <p>Polymorphous low-grade adenocarcinoma is a distinct neoplasm of the salivary gland composed of luminal and non-luminal tumor cells admixed in varying proportions. Its resemblance to lobular carcinoma of the breast had led to its earlier nomenclature of 'terminal duct carcinoma'. Most patients present with an asymptomatic mass in the hard palate. In rare cases, the mass can also occur in the tongue. We report an unusual case of polymorphous low-grade adenocarcinoma at the base of tongue.</p> <p>Case presentation</p> <p>A 47-year-old Asian Caucasian woman presented with a painless swelling at the right lateral border of the tongue with an intact overlying mucosa. There were no other associated complaints. The lesion was excised and subjected to histopathological examination that revealed an interesting and unusual morphology of polymorphous low-grade adenocarcinoma.</p> <p>Conclusion</p> <p>Polymorphous low-grade adenocarcinoma is a well-defined entity in the minor salivary glands. Its occurrence in the tongue is rare with very few cases reported in the literature. It is a malignant neoplasm with low aggressiveness and it is thus important to identify and treat it accordingly.</p
CT Findings of an Ectopic Pancreas in the Anterior Mediastinum
We report here on a rare case of an ectopic pancreatic tissue in the anterior mediastinum. A 32-year-old woman without any symptoms was transferred to our hospital because of an abnormal large mediastinal shadow on her chest radiograph during a checkup. The computed tomography (CT) scan revealed a giant cystic-solid mass that measured 16 × 13 × 8 cm and it was located in the center of the anterior mediastinum and it symmetrically grew to two sides. On enhanced CT scans, the solid component of the mass showed marked enhancement. We performed total surgical resection of the mass and complete pancreatic tissues were verified on the pathological examination
Old Age Prejudice in Mexican University Students: Comparisons by Gender
The goal of the present research was to compare the profiles of old age prejudice in male and female students from the area of physical activity. The study was conducted from January to October 2016. Participants were recruited from different semesters of the Physical Education and Human Motricity bachelor’s degrees offered at the Faculty of Physical Culture Sciences of the Autonomous University of Chihuahua, Mexico. The sample was obtained through convenience sampling, and included 1652 participants; 828 women and 824 men, mean age was 20.51 ± 1.83 years 20.90 ± 2.03 years respectively. The approach of the study was quantitative with a descriptive survey-like design. All participants completed the Questionnaire on Negative Stereotypes towards Old Age. Results from the Multivariate Analyses of Variance, and the follow-up Univariate Analyses of Variance, show that men report greater levels of prejudice towards old age on the sociomotivational (F = 31.657, p<.001) and character-personality (F = 15.789, p<.001) factors. No differences were found on the health factor (i.e., mental and physical). These results suggest that when designing any type of intervention in which the purpose isto improve the perception of young people towards the elderly, the variable gender should be considered. Future research should replicate these findings in larger samples
Polymorphous low-grade adenocarcinoma of the upper lip: 11 cases of an uncommon diagnosis
ObjectiveThe aim of this case study was to describe an international case series of polymorphous low-grade adenocarcinoma (PLGA) affecting the upper lip.Material and MethodsOver a 30-year-period, the files of five pathology services were reviewed for PLGA affecting the upper lip. Hematoxylin and eosin–stained slides were reviewed by three oral and maxillofacial pathologists, and microscopic features were described. Clinical data were retrieved from patients' medical records.ResultsThe review identified 11 cases of upper lip PLGAs, with a complete set of clinical data available for 5 cases. There was a male predominance (1.2:1), and the mean age was 58.7 years. Most cases presented as small asymptomatic swellings that resembled benign tumors. All patients underwent surgery, and no recurrences or metastases were reported in the 8 cases from which follow-up data were available. Microscopically, the typical polymorphic architectural arrangement of PLGA was seen in all cases, with lobular, trabecular, papillary, and cribriform patterns identified. Perineural invasion, normal gland entrapment, Indian filing, and concentric growth were frequently identified.ConclusionPLGA must be included in the list of differential diagnoses of tumors affecting the upper lip because of its similar clinical presentation to benign entities. The follow-up data available from 8 of 11 cases suggest that these tumors follow a low-grade clinical course, similar to the majority of palatal cases of PLGA
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