Conflito e Triangulação Coparental, Regulação Emocional e Problemas Externalizantes em Adolescentes: Relações diretas e indiretas

Las dificultades en la coparentalidad reverberan en problemas de externalización en adolescentes. Sin embargo, existe una falta de comprensión sobre los mecanismos que median esta relación. La regulación emocional es un posible vínculo entre estos constructos. El objetivo de este estudio fue probar un modelo estructural en el que la desregulación emocional es mediadora entre la coparentalidad y los problemas de externalización en adolescentes. Este es un estudio cuantitativo, transversal y explicativo. Cuenta con una muestra de 229 adolescentes entre 11 y 18 años que viven en el interior de Rio Grande do Sul. Se utilizó el modelo de ecuaciones estructurales para probar la validez empírica del modelo teórico propuesto. Los resultados proporcionaron evidencia para el avance del estudio de las relaciones familiares y los mecanismos explicativos en el desarrollo de problemas de externalización. Algunos dominios de desregulación emocional median la asociación entre las dimensiones negativas de los problemas de coparentalidad y problemas de externalización. Se analizan y discuten las relaciones directas e indirectas entre las variables del modelo.Dificuldades no exercício da coparentalidade reverberam em problemas externalizantes em adolescentes. Entretanto, há escassez no entendimento sobre mecanismos que medeiam essa relação. A regulação emocional apresenta-se como possível ligação entre esses construtos. O objetivo deste estudo foi testar um modelo estrutural no qual a desregulação emocional é mediadora entre coparentalidade e problemas externalizantes em adolescentes. Trata-se de estudo com delineamento quantitativo, transversal, explicativo. Contou com uma amostra de 229 adolescentes entre 11 a 18 anos, residentes no interior do Rio Grande do Sul. Foi utilizada modelagem de equações estruturais para testar a validade empírica do modelo teórico proposto. Os resultados forneceram evidências para o avanço do estudo das relações familiares e mecanismos explicativos no desenvolvimento de problemas externalizantes. Alguns domínios de desregulação emocional são mediadores da associação entre dimensões negativas de coparentalidade e problemas externalizantes. As relações diretas e indiretas entre as variáveis do modelo são analisadas e discutidas.Difficulties in coparenting performance reverberate in externalizing problems in adolescents. However, understanding on the mechanisms mediating this relationship is scarce. Emotion regulation is a possible link between these constructs. This study aims to test a structural model in which emotional dysregulation mediates coparenting and externalizing problems in adolescents. This is a quantitative, cross-sectional, and explanatory study. The sample consisted of 229 adolescents aged between 11 and 18, living in inland cities of Rio Grande do Sul. Structural equation modeling was used to test the empirical validity of the proposed theoretical model. Results provided evidence for the advance of the study on family relationships and explanatory mechanisms in the development of externalizing problems. Some domains of emotion deregulation mediate the association between coparenting negative dimensions and externalizing problems. Direct and indirect relationships between the model variables are analyzed and discussed

Efeito do tratamento prolongado com ácido gálico em animais diabéticos : uma abordagem comportamental e neuroprotetora

Orientadora: Janaina Menezes Zanoveli.Coorientadora: Helen de Morais.Monografia (bacharelado) - Universidade Federal do Paraná. Setor de Ciências Biológicas. Curso de Graduação em Ciências Biológicas

A preservação da informação e a construção de memória nas redes sociais: o caso do arquivo de comunidades do Orkut

As redes sociais na internet são uma crescente realidade no século XXI, onde cada vez mais surgem novos sites, com a proposta de proporcionar diferentes formas de interação entre seus usuários. Deve ser levado em consideração a presença constante das redes sociais na internet na vida de seus usuários e a grande rotatividade que ocorre entre diferentes plataformas e redes sociais na internet, destacando a quantidade imensurável de informações que são compartilhadas, e como a memória do indivíduo está localizada nestas páginas on-line. Com isso, cabe ressaltar a importância e a preocupação sobre a perda destas informações e como a memória do indivíduo é construída e preservada nestas páginas. No presente trabalho, será realizada uma pesquisa descritiva e exploratória a fim de averiguar a importância da preservação da informação nas redes sociais na internet. Será realizado um estudo de caso a respeito da plataforma criada pelo Google e nomeada de Arquivo de Comunidades do Orkut, que tem como pressuposto principal ser uma plataforma responsável por salvaguardar as informações dos usuários que mantinham interações nas “comunidades” da extinta rede social na internet chamada Orkut. Nesta plataforma estariam depositadas todas as trocas informacionais que ocorreram dentro de suas “comunidades” ao longo do tempo de funcionamento do Orkut. Neste trabalho serão analisadas três comunidades encontradas nesta plataforma, sendo elas as comunidades de “Rock in Rio, “F.R.I.E.N.D.S.” e “Livros”. Na análise realizada, chegou-se à conclusão que a plataforma criada pelo Google corresponde a sua intenção inicial de salvaguardar as informações de seus usuários, sendo entendida como uma importante ferramenta de preservação digital. Pretende-se com este estudo reforçar a importância da preservação da informação e a salvaguarda da memória em meio a realidade dos usuários das redes sociais na internet e como indivíduos e instituições precisam de se preocupar a respeito deste tema

Dimensões Negativas da Coparentalidade e Sintomas Internalizantes: A Regulação Emocional como Mediadora

The objective of this study was to test a structural model in which emotional regulation mediates the negative dimensions of coparenting and internalizing symptoms in adolescents. The sample consisted of 229 adolescents aged 11 to 18 years. Structural equations modeling was used to test the empirical validity of the proposed theoretical model. The results indicated that emotional regulation mediates the association between negative dimensions of coparenting and internalizing symptoms in adolescents. In contrast, a direct link between coparenting and internalizing symptoms did not remain significant in the mediation model. It is concluded that emotional regulation plays a determining role in the development of internalizing symptoms in the context of coparental difficulties.O objetivo deste estudo foi testar um modelo estrutural no qual a regulação emocional é mediadora entre dimensões negativas da coparentalidade e sintomas internalizantes em adolescentes. A amostra foi composta de 229 adolescentes entre 11 a 18 anos. Modelagem de equações estruturais foi utilizada para testar a validade empírica do modelo teórico proposto. Os resultados indicaram que regulação emocional é mediadora da associação entre dimensões negativas de coparentalidade e sintomas internalizantes em adolescentes. Em contraste, associação direta entre coparentalidade e sintomas internalizantes não se manteve significativa no modelo com mediação. Conclui-se que a regulação emocional possui papel determinante para o desenvolvimento de sintomas internalizantes no contexto de dificuldades coparentais

Nile tilapia broodfish fed high‐protein diets: Digestive enzymes in eggs and larvae

The aim of this study was to assess the activity of gastric, pancreatic and intestinal digestive enzymes during the embryonic and larval development of Nile tilapia (Oreochromis niloticus) GIFT strain Aqua America® 1 obtained from a broodstock fed two levels of crude protein (CP). A total of 72 females and 24 males, 10 hapas, two CP levels (32% and 38%) and six phases of embryonic (cleavage, blastula, gastrula) and larval (hatching, 7 and 10 days post hatch, dph) stages were used. The eggs were collected in cleavage, blastula and gastrula stages, 300 mg was collected, and kept in cryogenic tubes in liquid nitrogen. For the samples at larval stage, the remaining eggs were separated according to crude protein level and kept in hatcheries and samples were collected on 7 and 10 dph the same way as before. A total of 48 samples were collected: at each protein level (32% and 38% CP), four samples were collected in each phase of embryonic and larval development. Statistical differences were not observed during embryonic development for acid proteases, trypsin, amylase and lipase activity at both levels of crude protein (32 and 38% CP). Differences for acid proteases were noticed on 7 dph; trypsin and amylase on 7 dph and 10 dph. Significant differences on blastula and 7 dph for protease; as for aminopeptidase, there was significant difference on 7 dph. The data indicated early appearance of digestive enzymes in Nile tilapia broodfish receiving 32% CP taking into account the rapid growth and development of this species.info:eu-repo/semantics/acceptedVersio

From Data Mining of Chitinophaga sp. Genome to Enzyme Discovery of a Hyperthermophilic Metallocarboxypeptidase.

For several centuries, microorganisms and enzymes have been used for many different applications. Although many enzymes with industrial applications have already been reported, different screening technologies, methods and approaches are constantly being developed in order to allow the identification of enzymes with even more interesting applications. In our work, we have performed data mining on the Chitinophaga sp. genome, a gram-negative bacterium isolated from a bacterial consortium of sugarcane bagasse isolated from an ethanol plant. The analysis of 8 Mb allowed the identification of the chtcp gene, previously annotated as putative Cht4039. The corresponding codified enzyme, denominated as ChtCP, showed the HEXXH conserved motif of family M32 from thermostable carboxypeptidases. After expression in E. coli, the recombinant enzyme was characterized biochemically. ChtCP showed the highest activity versus benziloxicarbonil Ala-Trp at pH 7.5, suggesting a preference for hydrophobic substrates. Surprisingly, the highest activity of ChtCP observed was between 55 °C and 75 °C, and 62% activity was still displayed at 100 °C. We observed that Ca2+, Ba2+, Mn2+ and Mg2+ ions had a positive effect on the activity of ChtCP, and an increase of 30 °C in the melting temperature was observed in the presence of Co2+. These features together with the structure of ChtCP at 1.2 Å highlight the relevance of ChtCP for further biotechnological applications

Ionic regulation and shell mineralization in the bivalve Anodonta cygnea following heavy metal exposure

Freshwater mussels are one of the most imperiled faunistic groups in the world and environmental exposure to toxic heavy metals, which result in deregulation of calcium absorption and deposition in the laboratory, may be a contributing factor in their decline. To address potential effects of heavy-metal exposure on calcium transport and metabolism in freshwater bivalves, adult Anodonta cygnea (L., 1758) were exposed to a sublethal concentration (1.0 × 10−6 mol/L) of essential (Zn2+ and Cu2+) or nonessential (Pb2+ and Cr3+) metal for 30 days in the laboratory. Inorganic composition of extrapallial, haemolymph, heart, and pericardium fluids, and kidney tissue, as well as shell morphology by scanning electron microscopy, were compared in treated and untreated mussels. Calcium levels in fluids varied after exposure to any of the metals investigated, although the magnitude and threshold of effect were metal- and compartment-specific. Ca2+ levels increased robustly in all fluids following exposure to Zn2+, Cu2+, or Cr3+, whereas levels decreased significantly in heart fluid alone following Pb2+ exposure (p < 0.05). In constrast to exposure to the other metals, Cu2+ revealed an interesting reverse-accumulation pattern, decreasing in the fluids but not in the kidney, where it clearly accumulates for excretion. In addition, whereas essential Cu2+ and Zn2+ are closely regulated, the nonessential metals Pb2+ and Cr3+ increase to very high levels. Drastic alterations in shell morphology, specifically the structure of border and inner pallial regions of the nacreous layer, were observed after Cu2+ or Cr3+ exposure. Collectively, data suggest that prolonged exposure to a sublethal concentration of these heavy metals can adversely affect compartmental calcium availability and shell composition in A. cygnea

Bolton ratios in Portuguese subjects among different malocclusion groups

Several methods have been described to estimate inter-arch tooth size relationship, such as Bolton?s ratios. The aims of this study were to verify the validity of Bolton indexes in a sample of untreated Portuguese subjects based on Angle classification and to evaluate the gender difference. 168 pre-treatment dental casts of orthodontics Portuguese subjects (59 males and 109 females) with different occlusions were used, which were selected randomly from 541 consecutively treated orthodontic patients. The mesiodistal widths from first molar to first molar were measured on each pre-treatment cast to the nearest 0.01 mm using digital caliper, and Bolton?s anterior and overall ratios were calculated. Descriptive statistics as mean, standard deviation and range were calculated. Moreover, the results were compared to Bolton?s ratios and differences based on gender and occlusion groups were evaluated by statistical inference methods. The results reveal that the mean values, standard deviation and range were larger than Bolton?s in normal occlusion group (78.3±3.5% in anterior ratio and 92.1±2.2% in overall ratio) and there were no differences between genders (p >0.05). Class I (anterior and overall ratios, p=0.001 and p<0.001, respectively), Class II/2 (anterior ratio, p=0.032) and Class III (overall ratio, p=0.041) were significantly different from Bolton?s reference data. The results showed no differences between gender and no difference between normal occlusion and malocclusion groups. Moreover, in normal occlusion group, the anterior and overall tooth size ratios was equivalent to the original Bolton?s ratios, although the mean and standard deviation were large