QCD and strongly coupled gauge theories : challenges and perspectives

We highlight the progress, current status, and open challenges of QCD-driven physics, in theory and in experiment. We discuss how the strong interaction is intimately connected to a broad sweep of physical problems, in settings ranging from astrophysics and cosmology to strongly coupled, complex systems in particle and condensed-matter physics, as well as to searches for physics beyond the Standard Model. We also discuss how success in describing the strong interaction impacts other fields, and, in turn, how such subjects can impact studies of the strong interaction. In the course of the work we offer a perspective on the many research streams which flow into and out of QCD, as well as a vision for future developments.Peer reviewe

Comparing pre- and post-pandemic greenhouse gas and noise emissions from road traffic in Rome (Italy): a multi-step approach

This study presents the results of a traffic simulation analysis and emissions (greenhouse gas and noise) assessment comparing pre-pandemic (2019) and post-pandemic (2022) periods. The estimation of road traffic demand is based on conventional data sources and floating car data; next, the traffic simulation procedure was performed providing road network traffic volumes, which are the input for the emission models. The diffusion of teleworking, e-commerce, as well as the digitization of many processes, services and activities, lead to a significant change in urban mobility. Results show a significant though still not complete resumption of commuters travel activity (-10% compared to pre-pandemic period) in the morning peak-hour. This translates into an 11% reduction of greenhouse gas emissions and a 0.1% increase in noise emissions

Early stages of nucleation in the InAs/GaAs(001) heteroepitaxial growth

We have analysed by atomic force microscopy the InAs on GaAs(001) system prepared by molecular beam epitaxy. Subsequent stages of the heteroepitaxial growth have been investigated starting from the initial formation of the strained two-dimensional wetting layer up to the growth of three-dimensional self-assembled quantum dots. In particular, we report on the structural characterization near the critical thickness and discuss the role of different features that influence the morphology of InAs quantum dots

Nrf2-interacting nutrients and COVID-19 : time for research to develop adaptation strategies

There are large between- and within-country variations in COVID-19 death rates. Some very low death rate settings such as Eastern Asia, Central Europe, the Balkans and Africa have a common feature of eating large quantities of fermented foods whose intake is associated with the activation of the Nrf2 (Nuclear factor (erythroid-derived 2)-like 2) anti-oxidant transcription factor. There are many Nrf2-interacting nutrients (berberine, curcumin, epigallocatechin gallate, genistein, quercetin, resveratrol, sulforaphane) that all act similarly to reduce insulin resistance, endothelial damage, lung injury and cytokine storm. They also act on the same mechanisms (mTOR: Mammalian target of rapamycin, PPAR gamma:Peroxisome proliferator-activated receptor, NF kappa B: Nuclear factor kappa B, ERK: Extracellular signal-regulated kinases and eIF2 alpha:Elongation initiation factor 2 alpha). They may as a result be important in mitigating the severity of COVID-19, acting through the endoplasmic reticulum stress or ACE-Angiotensin-II-AT(1)R axis (AT(1)R) pathway. Many Nrf2-interacting nutrients are also interacting with TRPA1 and/or TRPV1. Interestingly, geographical areas with very low COVID-19 mortality are those with the lowest prevalence of obesity (Sub-Saharan Africa and Asia). It is tempting to propose that Nrf2-interacting foods and nutrients can re-balance insulin resistance and have a significant effect on COVID-19 severity. It is therefore possible that the intake of these foods may restore an optimal natural balance for the Nrf2 pathway and may be of interest in the mitigation of COVID-19 severity.Peer reviewe