HbbTV-compliant Platform for Hybrid Media Delivery and Synchronization on Single- and Multi-Device Scenarios

[EN] The combination of broadcast and broadband (hybrid) technologies for delivering TV related media contents can bring fascinating opportunities. It is motivated by the large amount and diversity of media contents, together with the ubiquity and multiple connectivity capabilities of modern consumption devices. This paper presents an end-to-end platform for the preparation, delivery, and synchronized consumption of related hybrid (broadcast/broadband) media contents on a single device and/or on multiple close-by devices (i.e., a multi-device scenario). It is compatible with the latest version of the Hybrid Broadcast Broadband TV (HbbTV) standard (version 2.0.1). Additionally, it provides adaptive and efficient solutions for key issues not specified in that standard, but that are necessary to successfully deploy hybrid and multidevice media services. Moreover, apart from MPEG-DASH and HTML5, which are the broadband technologies adopted by HbbTV, the platform also provides support for using HTTP Live Streaming and Real-time Transport Protocol and its companion RTP Control Protocol broadband technologies. The presented platform can provide support for many hybrid media services. In this paper, in order to evaluate it, the use case of multi-device and multi-view TV service has been selected. The results of both objective and subjective assessments have been very satisfactory, in terms of performance (stability, smooth playout, delays, and sync accuracy), usability of the platform, usefulness of its functionalities, and the awaken interest in these kinds of platforms.This work was supported in part by the "Fondo Europeo de Desarrollo Regional" and in part by the Spanish Ministry of Economy and Competitiveness through R&D&I Support Program under Grant TEC2013-45492-R.Boronat, F.; Marfil-Reguero, D.; Montagud, M.; Pastor Castillo, FJ. (2017). HbbTV-compliant Platform for Hybrid Media Delivery and Synchronization on Single- and Multi-Device Scenarios. IEEE Transactions on Broadcasting. 1-26. https://doi.org/10.1109/TBC.2017.2781124S12

Pedro Miralles Claver's sideboard and dresser Poynton

[EN] Pedro Miralles Claver, Valencian architect and designer, with a brief career in which he managed to leave an extensive legacy, elegant and magnificent designs marked by his strong personality. He found its foundations in the rigor of Neoclassicism, and the formal and material sumptuousness Art Deco. Reflection, the timelessness, the perceived quality of the proportions, the rediscovery of classical types and quality materials are features which define each of his objects. One expression of this thought is the set of sideboard and dresser Poynton, which was designed to be part of the Azimut collection, promoted in 1988 by Artespaña. Taking as reference the aesthetic value of the late nineteenth century, Miralles created a set of furniture, for whose manufacture he specified a high quality materials like oak and ebony macassar, on which applied decorative-based of fine marquetry and inlays of precious materials, all worked using traditional methods, controlling even the most detail, and finished on top with a “trompe-l'oeil” drawing. The whole final design made evident the interest of Pedro to recover the constructive elements from ancient cultures and give them new meanings.[ES] Pedro Miralles Claver, arquitecto y diseñador valenciano, con una breve trayectoria profesional en la que consiguió dejar un amplio legado de diseños llenos de elegancia y sobriedad, marcados por su fuerte personalidad. Encontró sus propios fundamentos en la rigurosidad del neoclasicismo, y en la suntuosidad formal y material del Art Decó. La reflexión, la atemporalidad, la calidad percibida en las proporciones, el redescubrimiento de tipologías clásicas y materiales nobles, son características que definen a cada uno de sus objetos. Una de las expresiones de este pensamiento es el juego de aparador y comodita Poynton, diseñado para formar parte de la colección Azimut, promovida por Artespaña en 1988. Tomando como fuente de referencia el valor de la estética de finales del siglo XIX, Miralles creó un conjunto de muebles, para cuya manufactura precisó de materiales de alta calidad como madera de roble y ébano de macasar, sobre los que aplicó motivos decorativos a base de marquetería fina e incrustaciones de materiales preciosos, todo ello trabajado de manera artesanal, controlando hasta el más mínimo detalle, y rematado en la parte superior con el dibujo de un cruz romana mediante la técnica del trompe-l´oeil. El conjunto del diseño final dejó constancia del interés de Pedro por recuperar los elementos constructivos de antiguas culturas y dotarlos de nuevos significados.Mellado Lluch, MP.; Pastor Castillo, FJ. (2015). Aparador y comodita Poynton, de Pedro Miralles Claver. Res Mobilis: Revista Internacional de Investigación en Mobiliario y Objetos Decorativos. 4(4):156-166. doi:10.17811/rm.4.2015.157-166S1561664

La transición hacia la Universidad: un reto para no caer en el vacío

La importancia que la transición educativa alcanza en el acceso a la Universidad precisa de un trabajo de regulación que en estos momentos no existe. En base a la información previa obtenida de los centros de secundaria sobre la transición primaria – secundaria, y sobre las actividades que se realizan dentro del Plan de Acción Tutorial, se elabora una propuesta sobre la que generar un programa de transición secundaria – universidad. Contamos como recursos, con un centro de secundaria piloto, y el Programa de Acción Tutorial de la Universidad de Alicante. El Programa de Transición Universitaria establece una serie de actividades en coordinación, y recoge además actividades de intervención directa con el alumnado de secundaria. Una de ellas sería plan de intervención integral que incluye, además de los aspectos técnicos necesarios, aspectos personales. Se delimitan los contenidos, la metodología, los recursos, el calendario de aplicación y los responsables, y esta actividad generada desde la Universidad, estará incluida en el Plan de Acción Tutorial del Instituto

Safety and Efficacy of an Oncolytic Adenovirus as an Immunotherapy for Canine Cancer Patients

The use of oncolytic virus is an innovative approach that has shown promising results as a treatment in oncology. Epithelial-derived tumors are the most frequent neoplasms in dogs, but gold standard therapies can be highly invasive procedures. Due to the accessible localization of these tumors, the intratumoral administration is feasible. Therefore, we propose to determine the safety and efficacy of intratumoral administration of oncolytic adenovirus ICOCAV15, in canine patients with epithelial-derived tumors. Eight dogs with carcinoma/adenocarcinoma were intratumorally treated with ICOCAV15. No clinically relevant changes were observed in the blood count, biochemistry and coagulation test analyzed during follow-up. The survival time of the 6/8 dogs exceeded the median survival time with chemotherapy, showing a partial response rate of 25% and 75% of stable disease. ICOCAV15 was detected in the target lesion by qPCR and immunohistochemistry. Also, some of the non-treated metastasis showed an infiltration of ICOCAV15 by immunohistochemistry. The immune populations were evaluated, and an increase of CD8+, MAC387+, CD3+ and CD20+ cells was reported in some of the patients after the inoculation. These results show that intratumoral ICOCAV15 is safe and well tolerated by dogs. Also, they suggest ICOCAV15 could be a new tool in veterinary oncology for accessible carcinomas/adenocarcinomas. The use of oncolytic viruses is an innovative approach to lyse tumor cells and induce antitumor immune responses. Eight dogs diagnosed with carcinoma/adenocarcinoma were intratumorally treated with ICOCAV15, an oncolytic canine adenovirus (CAV). To evaluate the treatment's safety, a blood count, biochemistry, and coagulation test were performed before treatment and during follow-up. Immune populations were analyzed by flow cytometry. Anti-adenovirus antibodies were also determined. The immune infiltration, vascularization, and viral presence in the tumor were determined by CD3, CD4, CD20, CD31 and CAV by immunohistochemistry. All the dogs maintained a good quality of life during follow-up, and some had increased median survival time when compared with dogs treated with chemotherapy. No treatment-related adverse effects were detected. The Response Evaluation Criteria In Solid Tumors criteria were also assessed: two patients showed a partial response and the rest showed stable disease at various times during the study. ICOCAV15 was detected inside the tumor during follow-up, and antiviral antibodies were detected in all patients. Furthermore, the tumor-infiltrating immune cells increased after viral administration. Therefore, we suggest that intratumorally administered ICOCAV15 could represent as a new tool for the treatment of canine carcinoma because it is safe, well-tolerated by dogs, and shows promising results

Club Senior VIP

Este proyecto ha sido elaborado para satisfacer la necesidad de adultos mayores autovalentes, de gozar de un centro de esparcimiento especialmente pensado en desarrollar hobbies y/o actividades inherentes al rango de edad de 60 a 80 años; tales como talleres de memoria, baile, natación, tai chi, entre otros. Esta idea surgió porque según el estudio de mercado realizado, hay muchos adultos mayores con necesidad de obtener un servicio diferenciado y especializado, y los familiares con los que viven - por el día a día -, no pueden satisfacer esa necesidad. La principal fuente de ingresos será la venta de membresías, para pasar el día y participar de las distintas actividades sujetas a cupo, y para además acceder a una residencia temporal que permite llevar una mejor calidad de vida de lunes a viernes en “Club Senior VIP”. Se estima que la inversión será distribuida principalmente en el alquiler e implementación del Centro, la contratación del personal especializado y una agresiva campaña publicitaria. Los impulsadores de este proyecto serán los alumnos de la UPC: Claudia Castro Hinojosa, quien será la responsable de la Jefatura de administración y ventas, 2. Cinthya Gonzalez Gentille, quien será la responsable de la Jefatura de operaciones y gestión de la calidad, 3. Martín Ruiz Pastor Castillo, quien será el responsable de marketing y ventas, y, 4. Evelyn Soto Polo, quien será la responsable de los recursos humanos.This project has been developed to meet the need for self-sufficient older adults, to enjoy a recreation center specially designed to develop hobbies and / or activities inherent in the age range of 60 to 80 years; such as memory workshops, dancing, swimming, tai chi, among others. This idea arose because according to our research, there are many older adults in need of obtaining a differentiated and specialized service, and the relatives who are in charge of them, for the day to day they cannot meet that need. The main source of income will be the sale of memberships, to spend the day and participate in the different activities subject to quota, and also to access a temporary residence that allows to lead a better quality of life from Monday to Friday in “Club Senior VIP”, Valuing the family union. An investment that will be distributed mainly in the rental and implementation of the Center, the hiring of specialized personnel and an advertising campaign. The promoters of this project will be the UPC students: Claudia Castro Hinojosa, who will be responsible for the administrative area. 2. Cinthya Gonzalez Gentille, who will be responsible for the operations and quality area. 3. Martín Ruiz Pastor Castillo, who will be responsible for the marketing and commercial area. 4. Evelyn Soto Polo, who will be responsible for the personnel area.Trabajo de investigació

Estudio comparativo de la evolución de los parámetros de calidad en pimiento verde almacenado a dos condiciones de temperatura

El pimiento (Capsicum annuum L.) es susceptible a desarrollar daños por frío (DPF) a temperaturas inferiores a 7 ºC. El objetivo del estudio es evaluar la evolución de los parámetros de calidad del pimiento verde, tipo ‘Lamuyo’, bajo dos regímenes de temperatura (2 y 7 ºC). Los resultados obtenidos mostraron una mayor pérdida de peso en los pimientos almacenados a 7 ºC. Por otro lado, los pimientos conservados a 2 ºC presentaron valores superiores de firmeza, sólidos solubles totales y acidez total en comparación con los pimientos almacenados a 7 ºC. Por último, los pimientos conservados en frío presentaron una incidencia elevada de DPF. En conclusión, los parámetros evaluados han mostrado que los pimientos almacenados a 2 ºC presentan una mayor calidad durante la conservación postcosecha. Sin embargo, dichos pimientos presentaron la mayor incidencia de DPF, derivando en la búsqueda de nuevas alternativas para la prevención de dicha alteración fisiológica

Superplastic deformation of directionally solidified nanofibrillar Al2O3-Y3Al5O12-ZrO2 eutectics

Nanofibrillar Al2O3–Y3Al5O12–ZrO2 eutectic rods were manufactured by directional solidification from the melt at high growth rates in an inert atmosphere using the laser-heated floating zone method. Under conditions of cooperative growth, the ternary eutectic presented a homogeneous microstructure, formed by bundles of single-crystal c-oriented Al2O3 and Y3Al5O12 (YAG) whiskers of ≈100 nm in width with smaller Y2O3-doped ZrO2 (YSZ) whiskers between them. Owing to the anisotropic fibrillar microstructure, Al2O3–YAG–YSZ ternary eutectics present high strength and toughness at ambient temperature while they exhibit superplastic behavior at 1600 K and above. Careful examination of the deformed samples by transmission electron microscopy did not show any evidence of dislocation activity and superplastic deformation was attributed to mass-transport by diffusion within the nanometric domains. This combination of high strength and toughness at ambient temperature together with the ability to support large deformations without failure above 1600 K is unique and shows a large potential to develop new structural materials for very high temperature structural applications

Tratamiento precosecha para la mejora en la frigo conservación de la granada “Mollar de Elche”

The postharvest storage of ‘Mollar de Elche’ pomegranate fruit during long periods, around 3 months, in optimum conditions (6-9ºC), could increase chilling injury incidence accompanied with quality losses of pomegranate fruits. In this experiment, the effect of methyl jasmonate (MeJa) at 5 mM, such as elicitor, by foliar treatment was study. This treatment was applied in differents plots, safeguarded by Protected Designation in Origin (PDO). The results showed that this preharvest treatment reduced a 40-60 % of chilling injury incidence in the internal and external husk compared to the untreated fruits during postharvest storage. On the other hand, treated fruits showed a greater physical-chemical property than control, leading into a higher fruit acceptability by consumers.A la Generalitat Valenciana (2020/VALORIZA/VSC/020) y a las empresas colaboradoras FRANCISCO OLIVA SL, Hermanos Fuentes C.B., HEBEGU SL y Antonio García Bernabé

Proximidad residencial a industrias y mortalidad por enfermedades cardiovasculares y cáncer en personas mayores: Estudio Seniors-ENRICA

XLI Reunión anual de la Sociedad Española de Epidemiología (SEE) y XVIII Congresso da Associação Portuguesa de Epidemiología (APE). Porto (Portugal), del 5 al 8 de septiembre de 2023.Antecedentes/Objetivos: Las enfermedades cardiovasculares (ECV) y el cáncer son las dos principales causas de muerte en el mundo. Su etiología no es única y, en el caso del cáncer, tiene una parte desconocida, por lo que se necesita seguir evaluando el papel de potenciales factores de riesgo asociados con estas enfermedades. El objetivo fue analizar la asociación entre proximidad residencial a industrias contaminantes y mortalidad por ECV y cáncer, teniendo en cuenta categorías de sectores industriales y contaminantes emitidos en el estudio Seniors-ENRICA. Métodos: Seniors-ENRICA es una cohorte representativa a nivel nacional de población mayor de 60 años no institucionalizada con un seguimiento de 10 años, cuyo objetivo es evaluar factores de riesgo ambientales que afectan a la salud de las personas mayores, incluyendo mortalidad por ECV y cáncer. La cohorte se estableció en 2008-2010 con 3289 individuos que contribuyeron con 8562 visitas bianuales. Se geocodificaron los domicilios de los individuos y las industrias y se calculó la distancia entre ellos. Como medida de efecto se estimó el hazard ratio (HR) y su intervalo de confianza al 95% (IC95%) asociado a la proximidad (distancias desde ≤ 2 km hasta ≤ 5 km) a industrias mediante modelos de regresión de Cox para riesgos competitivos, ajustando por variables sociodemográficas y de estilos de vida a nivel individual, y por índice de privación a nivel de sección censal. Resultados: Durante el seguimiento, se produjeron 136 muertes por ECV y 146 por cáncer. No se encontró asociación entre proximidad a industrias y mortalidad por ECV para ninguna de las distancias analizadas, con HRs oscilando entre 0,89 (≤ 4 km) y 0,99 (≤ 2 km). Para mortalidad por cáncer, se encontraron asociaciones (HR; IC95%) positivas para el conjunto de industrias en todas las distancias analizadas, desde ≤ 2 km (3,16; 1,60-6,26) hasta ≤ 5 km (2,57, 1,37-4,81). Por sectores industriales, destacan los excesos de riesgo (HR; IC95%) de morir por cáncer en el entorno (≤ 5 km) de astilleros (4,38; 1,67-11,48), cementeras (5,31; 1,31-21,49) e instalaciones de galvanizado (4,05; 1,59-10,33). Por contaminantes, los principales excesos de riesgo (HR; IC95%) se encontraron en el entorno (≤ 5 km) de industrias emisoras de antraceno (4,70; 1,71-12,93) antimonio (4,63; 2,01-10,64) y ftalatos (4,20; 1,58-11,14). Conclusiones/Recomendaciones: Los resultados sugieren que vivir cerca de industrias podría ser un factor de riesgo para la mortalidad por cáncer en población > 60 años, pero no para ECV.Financiación: CIBERESP-ESP21PI04.N

Modern Analogue Approach Applied to High-Resolution Varved Sediments-A Synthesis for Lake Montcortès (Central Pyrenees)

In Quaternary paleosciences, the rationale behind analogical inference presupposes that former processes can be explained by causes operating now, although their intensity and rates can vary through time. In this paper we synthesised the results of di erent modern analogue studies performed in a varved lake. We discuss their potential value to obtain best results from high resolution past records. Di erent biogeochemical contemporary processes revealed seasonality and year-to-year variability, e.g., calcite precipitation, lake oxygenation, production and deposition of pollen and phytoplankton growth. Fingerprints of the first two of these processes were clearly evidenced in the varve-sublayers and allow understanding related to past events. Pollen studies suggested the possibility of identifying and characterizing seasonal layers even in the absence of varves. Marker pigments in the water column were tightly associated with phytoplankton groups living today; most of them were identified in the sediment record as well. We observed that 50% of these marker pigments were destroyed between deposition and permanent burying. In another study, seasonality in the production/distribution of branched glycerol dialkyl glycerol tetraethers (brGDGTs) and derived temperature estimates were investigated in catchment soils and particles settling in the lake. The signatures of brGDGTs in depositional environments mainly were representative of stable conditions of soils in the catchment that last over decades; no brGDGTs seemed to be produced within the lake. The main contribution of this review is to show the advantages and limitations of a multiproxy modern-analogue approach in Lake Montcortès as a case study and proposing new working hypotheses for future research